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Jacob Piehler
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Journal Articles

Modulating G-CSFR Signaling Using De Novo Designed Cytokines

Timo Ullrich, Birte Hernandez Alvarez, Christoph Pollmann, Malte Ulrich Ritter, Jérémy Haaf, Narges Aghaallaei, Jacob Piehler, Ivan Tesakov, Maya El-Riz, Kateryna Maksymenko, Valeriia Hatskovska, Sergey Kandabarau, Maksim Klimiankou, Claudia Lengerke, Karl Welte, Andrei Lupas, Julia Skokowa, Mohammad ElGamacy
Journal: Blood
Blood (2024) 144 (Supplement 1): 4967.
https://doi.org/10.1182/blood-2024-209668
Published: 2024
Journal Articles

Preclinical Evaluation of INCB160058 - a Novel and Potentially Disease-Modifying Therapy for JAK2V617F Mutant Myeloproliferative Neoplasms

Matthew C. Stubbs, Hamza Celik, Yanran Ai, Xin He, Hong Chang, Angela Lei, Mark Rupar, Brittney Wass, Melody Diamond, Xiaoming Wen, Jun Li, Nina Zolotarjova, Alex Margulis, Gaurang Trivedi, Angelo B.A. Laranjeira, Cooper A. Taylor, Jennifer Rocha, Christoph Pollmann, Jacob Piehler, Bianca L. Ferreira, Ian Hitchcock, Ricardo Macarrón, Eddy W. Yue, Sunkyu Kim
Journal: Blood
Blood (2023) 142 (Supplement 1): 860.
https://doi.org/10.1182/blood-2023-179369
Published: 2023
Journal Articles

New Paradigms for the Mechanisms of Thrombopoietin Receptor Activation and Dysregulation By the JAK2 V617F Mutation

Stephan Wilmes, PhD, Maximillian Hafer, BSc, Tess A Stanly, Ignacio Moraga, PhD, Joni Vuorio, PhD, Chetan Poojari, PhD, Vivek Sharma, PhD, Sara Löchte, PhD, Katiuska Pulgar Prieto, BSc, Julie A Tucker, PhD, Stevan R Hubbard, PhD, K.Christopher Garcia, PhD, Ilpo Vattulainen, PhD, Ian Hitchcock, PhD, Jacob Piehler, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2962.
https://doi.org/10.1182/blood-2019-129234
Published: 2019
Journal Articles

Discovery of the First Pathogenic Human EPO Mutation Provides Mechanistic Insight into Cytokine Signaling

Ah Ram Kim, PhD, Jacob C Ulirsch, Stephan Wilmes, Ekrem Unal, Ignacio Moraga, Musa Karakukcu, Daniel Yuan, Shideh Kazerounian, Namrata Gupta, Stacey B Gabriel, PhD, Eric S Lander, PhD, Turkan Patiroglu, Alper Ozcan, Mehmet Ozdemir, Christopher Garcia, Jacob Piehler, Hanna Gazda, MD PhD, Daryl Klein, Vijay G Sankaran, MD PhD
Journal: Blood
Blood (2016) 128 (22): 331.
https://doi.org/10.1182/blood.V128.22.331.331
Published: 2016