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Journal Articles

Feasibility and utility of unmatched whole-genome sequencing (uWGS) for pediatric acute leukemias: An analysis of leukemia precision-based therapy (LEAP) study samples

Blood (2025) 146 (Supplement 1): 2561.

https://doi.org/10.1182/blood-2025-2561

Published: 2025

Journal Articles

Asciminib pediatric formulation shows a tolerable safety profile in pediatric patients with chronic myeloid leukemia in chronic phase (CML-CP): Second interim analysis from the ASC4KIDS study

Jessica Pollard, Hiroyuki Shimada, Shruti Kapoor, Matthias Hoch, Vishal Dhamal, Nithya Agrawal, Christine Rosko, Ana Paula Cardoso, Masakatsu Yanagimachi, Ho Joon Im, Markus Metzler, Nobuko Hijiya

Blood (2025) 146 (Supplement 1): 7312.

https://doi.org/10.1182/blood-2025-7312

Published: 2025

Journal Articles

Outcome of children and adolescents with newly diagnosed T-cell acute lymphoblastic leukemia: Results of DFCI ALL consortium protocol 16-001

Melissa Burns, Yael Flamand, Lynda Vrooman, Victoria Koch, Sarah Cronholm, Sarah Hunt, Marian Harris, Peter Cole, Lisa Gennarini, Nobuko Hijiya, Justine Kahn, Kara Kelly, Bruno Michon, Donna Neuberg, Andrew Place, Thai Tran, Jennifer Welch, Stephen Sallan, Lewis Silverman

Blood (2025) 146 (Supplement 1): 644.

https://doi.org/10.1182/blood-2025-644

Published: 2025

Journal Articles

Identifying barriers to clinical trial enrollment for children with relapsed or refractory hematologic malignancies

Blood (2025) 146 (Supplement 1): 4404.

https://doi.org/10.1182/blood-2025-4404

Published: 2025

Journal Articles

How I treat chronic myeloid leukemia in children and adolescents

Jing Chen, Meinolf Suttorp, Nobuko Hijiya

Blood blood.2024026514.

https://doi.org/10.1182/blood.2024026514

Published: 2025

Journal Articles

Retrospective Cohort Analysis of Response and Survival of Children, Adolescents, and Young Adults (CAYA) with Relapsed and/or Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-ALL) and Lymphoma (T-LL) Treated with Curative Intent: A TACL Consortium Study

Blood (2024) 144 (Supplement 1): 4187.

https://doi.org/10.1182/blood-2024-209138

Published: 2024

Journal Articles

Efficacy and Toxicity of Fixed Dose Versus Reduced/PK-Adjusted Dose Pegaspargase in Pediatric Patients with Newly Diagnosed Acute Lymphoblastic Leukemia: Results of DFCI ALL Consortium Protocol 16-001

Melissa A. Burns, Yael Flamand, Lynda M. Vrooman, Victoria B. Koch, Yves Theoret, Sarah M. Cronholm, Sarah K. Hunt, Peter D. Cole, Lisa M. Gennarini, Nobuko Hijiya, Justine M. Kahn, Kara M. Kelly, Bruno Michon, Donna S. Neuberg, Andrew E. Place, Thai Hoa Tran, Jennifer J.G. Welch, Stephen E. Sallan, Lewis B. Silverman

Blood (2024) 144 (Supplement 1): 307.

https://doi.org/10.1182/blood-2024-207273

Published: 2024

Journal Articles

Feasibility of Adjusting Risk Group and Risk Group-Based Therapy during Induction in the Treatment of B-Cell Acute Lymphoblastic Leukemia: Results from DFCI ALL Consortium Protocol 16-001

Lynda M. Vrooman, Yael Flamand, Melissa A. Burns, Victoria B. Koch, Sarah M. Cronholm, Sarah K. Hunt, Peter D. Cole, Lisa M. Gennarini, Marian H. Harris, Nobuko Hijiya, Justine M. Kahn, Kara M. Kelly, Bruno Michon, Andrew E. Place, Thai Hoa Tran, Jennifer J.G. Welch, Stephen E. Sallan, Lewis B. Silverman

Blood (2024) 144 (Supplement 1): 311.

https://doi.org/10.1182/blood-2024-208605

Published: 2024

Journal Articles

ASC4KIDS: A Multicenter, Open-Label, Phase Ib/II Study to Determine the Dose and Safety of Asciminib in Pediatric Patients with Chronic Myeloid Leukemia in the Chronic Phase

Nobuko Hijiya, Shruti Kapoor, Matthias Hoch, Laurence Descamps, Vishal Dhamal, Ana Paula Torres Cardoso

Blood (2023) 142 (Supplement 1): 6387.

https://doi.org/10.1182/blood-2023-185535

Published: 2023

Journal Articles

Antigen Directed Therapy Pre-Transplant Confers Superior Post-Transplant Survival Outcome Compared to Conventional Chemotherapy in Pediatric Patients with Relapsed and Refractory B-ALL

Blood (2022) 140 (Supplement 1): 7763–7765.

https://doi.org/10.1182/blood-2022-160272

Published: 2022

Journal Articles

ASC4KIDS: A Multicenter, Open-Label, Phase Ib/II Study to Determine the Dose and Safety of Asciminib in Pediatric Patients with Chronic Myeloid Leukemia in Chronic Phase

Nobuko Hijiya, Shruti Kapoor, Matthias Hoch, Laurence Descamps, Kohinoor Dasgupta, Nicholas Ramscar

Blood (2022) 140 (Supplement 1): 12204–12205.

https://doi.org/10.1182/blood-2022-162451

Published: 2022

Journal Articles

High-dose AraC is essential for the treatment of ML-DS independent of postinduction MRD: results of the COG AAML1531 trial

Blood (2021) 138 (23): 2337–2346.

https://doi.org/10.1182/blood.2021012206

Published: 2021

Includes: Supplemental data

Journal Articles

Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) in Pediatric Patients with Tagraxofusp, a CD123-Targeted Therapy

Naveen Pemmaraju, Branko Cuglievan, Joseph L Lasky, III, Albert Kheradpour, Nobuko Hijiya, Anthony S. Stein, Anna B Pawlowska

Blood (2021) 138 (Supplement 1): 2317.

https://doi.org/10.1182/blood-2021-150393

Published: 2021

Journal Articles

Trial in Progress: A Multicenter, Open-Label, Phase Ib/II Study to Determine the Dose and Safety of Asciminib in Pediatric Patients with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase Treated with ≥1 Prior Tyrosine Kinase Inhibitor

Nobuko Hijiya, Shruti Kapoor, Laurence Descamps, Mohamed Amine Bayar, Nicholas Ramscar

Blood (2021) 138 (Supplement 1): 2561.

https://doi.org/10.1182/blood-2021-151198

Published: 2021

Journal Articles

A Phase I/II Study of Bosutinib in Pediatric Patients with Resistant/Intolerant or Newly Diagnosed Philadelphia Chromosome-Positive Chronic Myeloid Leukemia, Study ITCC (Innovative Therapies for Children with Cancer European Consortium) 054 and COG (Children's Oncology Group Consortium) AAML1921: Results from the Phase I Trial in Resistant/Intolerant Patients

Blood (2021) 138 (Supplement 1): 2558.

https://doi.org/10.1182/blood-2021-145709

Published: 2021

Journal Articles

Gene Expression Analysis of CML Patients across the Age Spectrum

Blood (2021) 138 (Supplement 1): 1473.

https://doi.org/10.1182/blood-2021-148701

Published: 2021

Journal Articles

Distinct Genetic Pathways Define Leukemia Predisposition Versus Adaptive Clonal Hematopoiesis in Shwachman-Diamond Syndrome

Alyssa L. Kennedy, MDPhD, Kasiani C. Myers, MD, James Bowman, PhD, Christopher J. Gibson, MD, Gwen M. Muscato, Robert Klein, Kaitlyn Ballotti, Nicholas Camarda, Elissa M. Furutani, MD, Chad E. Harris, MS, Shanshan Liu, PhD, Ashley Galvin, Maggie Malsch, MSN, RN, David C. Dale, MD, John M Gansner, MD PhD, Taizo A. Nakano, MD, Alison A. Bertuch, MD, Adrianna Vlachos, MD, Jeff H. Lipton, MD PhD, Paul Castillo, MD, James Connelly, John Edwards, MD, Nobuko Hijiya, MD, Richard Ho, MD, Inga Hofmann, MD, James N Huang, MD, Sioban B. Keel, MD, Adam J. Lamble, MD, Bonnie W Lau, MD PhD, Kelly J. Walkovich, MD, Maxim Norkin, MD, Wendy Stock, MD, Steffen Boettcher, Christian Brendel, PhD, Elliot Stieglitz, MD, Mark D. Fleming, MD DPhil, Stella M. Davies, PhD MBBS, MRCP, Edie A. Weller, Chris Bahl, PhD, Scott L. Carter, PhD, Akiko Shimamura, MD PhD, R. Coleman Lindsley, MD PhD

Blood (2020) 136 (Supplement 1): 35–36.

https://doi.org/10.1182/blood-2020-137125

Published: 2020

Journal Articles

Comparison of the Transcriptomic Signatures in Pediatric and Adult CML

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-142270

Published: 2020

Journal Articles

Phase 2 study of nilotinib in pediatric patients with Philadelphia chromosome–positive chronic myeloid leukemia

Blood (2019) 134 (23): 2036–2045.

https://doi.org/10.1182/blood.2019000069

Published: 2019

Includes: Supplemental data

Journal Articles

How I treat chronic myeloid leukemia in children and adolescents

Nobuko Hijiya, Meinolf Suttorp

Blood (2019) 133 (22): 2374–2384.

https://doi.org/10.1182/blood.2018882233

Published: 2019

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Feasibility and utility of unmatched whole-genome sequencing (uWGS) for pediatric acute leukemias: An analysis of leukemia precision-based therapy (LEAP) study samples

Asciminib pediatric formulation shows a tolerable safety profile in pediatric patients with chronic myeloid leukemia in chronic phase (CML-CP): Second interim analysis from the ASC4KIDS study

Outcome of children and adolescents with newly diagnosed T-cell acute lymphoblastic leukemia: Results of DFCI ALL consortium protocol 16-001

Identifying barriers to clinical trial enrollment for children with relapsed or refractory hematologic malignancies

How I treat chronic myeloid leukemia in children and adolescents

Retrospective Cohort Analysis of Response and Survival of Children, Adolescents, and Young Adults (CAYA) with Relapsed and/or Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-ALL) and Lymphoma (T-LL) Treated with Curative Intent: A TACL Consortium Study

Efficacy and Toxicity of Fixed Dose Versus Reduced/PK-Adjusted Dose Pegaspargase in Pediatric Patients with Newly Diagnosed Acute Lymphoblastic Leukemia: Results of DFCI ALL Consortium Protocol 16-001

Feasibility of Adjusting Risk Group and Risk Group-Based Therapy during Induction in the Treatment of B-Cell Acute Lymphoblastic Leukemia: Results from DFCI ALL Consortium Protocol 16-001

ASC4KIDS: A Multicenter, Open-Label, Phase Ib/II Study to Determine the Dose and Safety of Asciminib in Pediatric Patients with Chronic Myeloid Leukemia in the Chronic Phase

Antigen Directed Therapy Pre-Transplant Confers Superior Post-Transplant Survival Outcome Compared to Conventional Chemotherapy in Pediatric Patients with Relapsed and Refractory B-ALL

ASC4KIDS: A Multicenter, Open-Label, Phase Ib/II Study to Determine the Dose and Safety of Asciminib in Pediatric Patients with Chronic Myeloid Leukemia in Chronic Phase

High-dose AraC is essential for the treatment of ML-DS independent of postinduction MRD: results of the COG AAML1531 trial

Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) in Pediatric Patients with Tagraxofusp, a CD123-Targeted Therapy

Trial in Progress: A Multicenter, Open-Label, Phase Ib/II Study to Determine the Dose and Safety of Asciminib in Pediatric Patients with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase Treated with ≥1 Prior Tyrosine Kinase Inhibitor

Gene Expression Analysis of CML Patients across the Age Spectrum

Distinct Genetic Pathways Define Leukemia Predisposition Versus Adaptive Clonal Hematopoiesis in Shwachman-Diamond Syndrome

Comparison of the Transcriptomic Signatures in Pediatric and Adult CML

Phase 2 study of nilotinib in pediatric patients with Philadelphia chromosome–positive chronic myeloid leukemia

How I treat chronic myeloid leukemia in children and adolescents

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