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Eric S. Schafer
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Journal Articles

Understanding the Associations between High-Dose Methotrexate Pharmacokinetics and the Risk of Adverse Events in Children and Adolescents with Down Syndrome Associated High-Risk Acute Lymphoblastic Leukemia

Kate D. Westmoreland, Zachary L Taylor, Tamara P. Miller, Ashley Chavana, Karen R Rabin, Austin L Brown, Melanie Brooke Bernhardt, Eric S. Schafer, Maureen M. O'Brien, Sharon M. Castellino, Laura B. Ramsey
Journal: Blood
Blood (2024) 144 (Supplement 1): 1438.
https://doi.org/10.1182/blood-2024-211870
Published: 2024
Journal Articles

Retrospective Cohort Analysis of Response and Survival of Children, Adolescents, and Young Adults (CAYA) with Relapsed and/or Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-ALL) and Lymphoma (T-LL) Treated with Curative Intent: A TACL Consortium Study

Melinda G Pauly, Yueh-Yun Chi, Jemily Malvar, Roy Leong, Susan Colace, Nathan Gossai, Nobuko Hijiya, Chintan Parekh, Susan R Rheingold, Anupam Verma, Bill H Chang, Todd M Cooper, Andrew Doan, Yamilet Huerta, Kelly Elizabeth Faulk, Diane Hanna, Kenneth Matthew Heym, Mallorie M. Heneghan, Joel Kaplan, Luciano Dalla-Pozza, Seth E. Karol, Andrew E. Place, Jenna Rossoff, Eric S. Schafer, Tamra Slone, Michelle L. Hermiston, Maria Luisa Sulis
Journal: Blood
Blood (2024) 144 (Supplement 1): 4187.
https://doi.org/10.1182/blood-2024-209138
Published: 2024
Journal Articles

MRD at the end of induction and EFS in T-cell lymphoblastic lymphoma: Children’s Oncology Group trial AALL1231

CME Clinical Trials & Observations Brief Report
Robert J. Hayashi, Michelle L. Hermiston, Brent L. Wood, David T. Teachey, Meenakshi Devidas, Zhiguo Chen, Robert D. Annett, Barbara L. Asselin, Keith August, Steve Cho, Kimberly P. Dunsmore, Jason Lawrence Freedman, Paul J. Galardy, Paul Harker-Murray, Terzah M. Horton, Alok Jaju, Allison Lam, Yoav H. Messinger, Rodney R. Miles, Maki Okada, Samir Patel, Eric S. Schafer, Tal Schechter, Kristin A. Shimano, Neelam Singh, Amii Steele, Maria L. Sulis, Sarah L. Vargas, Stuart S. Winter, Charlotte Wood, Patrick A. Zweidler-McKay, Mignon L. Loh, Stephen P. Hunger, Elizabeth A. Raetz, Catherine M. Bollard, Carl E. Allen
Journal: Blood
Blood (2024) 143 (20): 2053–2058.
https://doi.org/10.1182/blood.2023021184
Published: 2024
Includes: Supplemental data
Journal Articles

Results from the Phase 1 Portion of a Trial of Oral Ixazomib Combined with Chemotherapy in Relapsed/Refractory Acute Lymphoblastic Leukemia or Lymphoma in Children, Adolescents and Young Adults: A Report from the Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) Consortium

Eric S. Schafer, Yueh-Yun Chi, Jemily Malvar, Teresa Rushing, Andrew Doan, Holly L. Pacenta, Reuven J. Schore, Richard Sposto, Roy Leong, Paul S. Gaynon, Jeffrey E. Rubnitz, Julio C. Barredo, Tamra Slone, Melinda Pauly, Alan S. Wayne, Deepa Bhojwani, Terzah M. Horton
Journal: Blood
Blood (2023) 142 (Supplement 1): 2872.
https://doi.org/10.1182/blood-2023-180414
Published: 2023
Journal Articles

Correlation of Minimal Residual Disease (MRD) at the End of Induction (EOI) and Event Free Survival (EFS) in T-Cell Lymphoblastic Lymphoma (T-LL), a Report from the Children's Oncology Group (COG) Trial AALL1231

Robert J. Hayashi, Michelle L. Hermiston, David T. Teachey, Meenakshi Devidas, Brent L. Wood, Zhiguo Chen, Robert D Annett, Barbara L Asselin, Keith J August, Steve Y Cho, Kimberly P. Dunsmore, Jason L. Freedman, Paul J. Galardy, Paul Harker-Murray, Terzah M. Horton, Alok I Jaju, Allison Lam, Yoav H. Messinger, Rodney R. Miles, Maki Okada, Samir I Patel, Eric S Schafer, Tal Schechter-Finkelstein, Kristin A. Shimano, Neelam Singh, Amii C. Steele, Maria Luisa Sulis, Sarah L Vargas, Stuart S. Winter, Charlotte Wood, Patrick A Zweidler-McKay, Mignon L. Loh, Stephen P. Hunger, Elizabeth A. Raetz, Catherine M Bollard, Carl Allen
Journal: Blood
Blood (2022) 140 (Supplement 1): 6387–6389.
https://doi.org/10.1182/blood-2022-159694
Published: 2022
Journal Articles

Severe Adverse Events Associated with Concentrations of High Dose Methotrexate in Pediatric Acute Lymphoblastic Leukemia Patients

Tamara P. Miller, Nicholas P. DeGroote, Zachary Taylor, Lauren Pommert, Oluwafunbi Awoniyi, Sarah Board, Ngozi Ugboh, Vivek Joshi, Allison Weisnicht, Nicholas Ambrosino, Melanie Brooke Bernhardt, Eric S Schafer, Maureen M. O'Brien, Sharon M. Castellino, Laura B. Ramsey
Journal: Blood
Blood (2022) 140 (Supplement 1): 2185–2186.
https://doi.org/10.1182/blood-2022-169741
Published: 2022
Journal Articles

Vincristine Sulfate Liposome Injection (VSLI, Marqibo®) in Combination with UK ALL-R3 Induction Chemotherapy for Children, Adolescents and Young Adults with Relapsed Acute Lymphoblastic Leukemia (ALL): A Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) Consortium Trial

Nirali N. Shah, Eric S Schafer, Kenneth Matthew Heym, Andrew E. Place, Melissa A. Burns, Nathan Gossai, Peter Shaw, Michael J. Burke, Bill H. Chang, Michelle L. Hermiston, Reuven J Schore, Teresa Rushing, Paul F Jarosinski, Richard Sposto, Ellynore Florendo, Jemily Malvar, Yueh-Yun Chi, James A. Whitlock, Lewis B. Silverman, Deepa Bhojwani, Alan S. Wayne
Journal: Blood
Blood (2021) 138 (Supplement 1): 3402.
https://doi.org/10.1182/blood-2021-149365
Published: 2021
Journal Articles

Intensification of Chemotherapy Using a Modified BFM Backbone for Children, Adolescents and Young Adults with T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL) Identifies Highly Chemorefractory Patients Who Benefit from Allogeneic Hematopoietic Stem Cell Transplantation

Paul Harker-Murray, Brent L. Wood, Meenakshi Devidas, Zhiguo Chen, Tal Schechter-Finkelstein, Robert J. Hayashi, Keith J August, Kimberly P. Dunsmore, Michelle L. Hermiston, Terzah M. Horton, Yoav H. Messinger, Sarah L Vargas, Eric S Schafer, Maria Luisa Sulis, Stuart S. Winter, Charlotte Wood, Catherine M Bollard, Mignon L. Loh, Stephen P Hunger, Elizabeth A. Raetz, David T. Teachey
Journal: Blood
Blood (2021) 138 (Supplement 1): 3487.
https://doi.org/10.1182/blood-2021-151837
Published: 2021
Journal Articles

Comparison of Severe Toxicities Following High Dose Methotrexate Administration By Demographics and over Time in Pediatric Patients with Acute Lymphoblastic Leukemia

Tamara P. Miller, Nicholas P. DeGroote, Lauren Pommert, Oluwafunbi Awoniyi, Sarah Board, Ngozi Ugboh, Vivek Joshi, Nicholas Ambrosino, Allison Weisnicht, Heidi Hsiao, Melanie Brooke Bernhardt, Eric S Schafer, Maureen M. O'Brien, Sharon M. Castellino, Laura B. Ramsey
Journal: Blood
Blood (2021) 138 (Supplement 1): 1970.
https://doi.org/10.1182/blood-2021-151081
Published: 2021
Journal Articles

Cranial Radiation Can be Eliminated in Most Children with T-Cell Acute Lymphoblastic Leukemia (T-ALL) and Bortezomib Potentially Improves Survival in Children with T-Cell Lymphoblastic Lymphoma (T-LL): Results of Children's Oncology Group (COG) Trial AALL1231

David T. Teachey, MD, Meenakshi Devidas, PhD, Brent L Wood, MD PhD, Zhiguo Chen, MS, Robert James Hayashi, MD, Robert D Annett, PhD, Barbara L Asselin, MD, Keith J August, MDMS, Steve Y Cho, MD, Kimberly P. Dunsmore, MD, Brian T. Fisher, DO, MSCE, Jason L. Freedman, MD, Paul J. Galardy, MD, Paul Harker-Murray, MD PhD, Michelle L. Hermiston, MD PhD, Terzah M Horton, MD PhD, Alok I Jaju, MD, Allison Lam, BCPS, Yoav H. Messinger, MD, Rodney R. Miles, MD PhD, Maki Okada, RN, Samir I Patel, MD, Eric S. Schafer, MD MHS, Tal Schechter-Finkelstein, MD, Kristin A. Shimano, MD, Neelam Singh, PhD, Amii C. Steele, PhD, Maria L. Sulis, MD, Sarah L Vargas, PhD, Stuart S. Winter, MD, Charlotte Wood, CCRP, Patrick Zweider McKay, MDPhD, Catherine M. Bollard, MD MBChB, Mignon L. Loh, MD, Stephen P. Hunger, MD, Elizabeth A. Raetz, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–12.
https://doi.org/10.1182/blood-2020-134730
Published: 2020
Journal Articles

Pharmacogenomic Association with Neurotoxicity in Hispanic Children with Acute Lymphoblastic Leukemia (ALL)

Claire A McClain, PharmD, M Brooke Bernhardt, PharmD, MS, Amanda Berger, PharmD, Ryan Winslow, BS, Michael E Scheurer, PhD MPH, Eric S. Schafer, MD MHS
Journal: Blood
Blood (2016) 128 (22): 3962.
https://doi.org/10.1182/blood.V128.22.3962.3962
Published: 2016
Journal Articles

Pcft Is Silenced By DNA Methylation In Pediatric Acute Lymphoblastic Leukemia Resulting In Decreased Methotrexate Uptake

Calvin K. Lee, MD, Weijie Poh, Megan Healey, PhD, Eric S Schafer, MD, Patrick Brown, MD, James G. Herman, MD
Journal: Blood
Blood (2013) 122 (21): 3768.
https://doi.org/10.1182/blood.V122.21.3768.3768
Published: 2013
Journal Articles

Lineage, Fusion Partner and Age Differences in the Methylome of MLL-r Leukemias

Eric S Schafer, MD, Rumen Kostadinov, PhD, Peter Murakami, MSc, Sandeep S. Negi, PhD, Maria E Figueroa, MD, Ari Melnick, MD, Patrick Brown, MD
Journal: Blood
Blood (2012) 120 (21): 3506.
https://doi.org/10.1182/blood.V120.21.3506.3506
Published: 2012
Journal Articles

Histone Profiling of Normal B-Precursors and Primary Pre-B Acute Lymphoblastic Leukemia Reveals Distinct Aberrant Histone Codes In MLL-Rearranged Vs. Wild Type MLL Leukemias That Correlate with Differential Expression of Key MLL Target Genes

Sandeep S. Negi, PhD, Eric S. Schafer, MD, Donald Small, MD, PhD, Patrick Brown, MD
Journal: Blood
Blood (2010) 116 (21): 2503.
https://doi.org/10.1182/blood.V116.21.2503.2503
Published: 2010
Journal Articles

Promoter Hypermethylation in MLL-r Leukemia: Biology and Therapeutic Targeting.

Eric S. Schafer, MD, Rafael Irizarry, Sandeep Negi, PhD, Emily McIntyre, Donald Small, MD, PhD, Maria E Figueroa, MD, Ari Melnick, Patrick Brown, MD
Journal: Blood
Blood (2009) 114 (22): 3472.
https://doi.org/10.1182/blood.V114.22.3472.3472
Published: 2009