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Journal Articles

Reprogramming glutamine metabolism enhances BCMA -CAR T-cell fitness and therapeutic efficacy in multiple myeloma

Blood (2025) 146 (24): 2931–2944.

https://doi.org/10.1182/blood.2024027496

Published: 2025

Includes: Supplemental data

Journal Articles

Innovative sdab-based CAR-T cells targeting BCMA outperform current CAR-T therapies for multiple myeloma

Vianca Ibarra-Garcia, Maria Erendira Calleja-Cervantes, Eva Molina, Franco Bernasconi-Bisio, Federica Rochira, Iñigo Azagra-Barber, Ines Ibañez-Sala, Saray Rodriguez-Diaz, Rebeca Martinez-Turrillas, Lucia Vanrell, Juan Lasarte, Ana Alfonso-Pierola, Paula Rodriguez-Otero, Jesus San-Miguel, Juan Roberto Rodriguez-Madoz, Antonio Pineda-Lucena, Felipe Prosper

Blood (2025) 146 (Supplement 1): 4072.

https://doi.org/10.1182/blood-2025-4072

Published: 2025

Journal Articles

Ending the undetermined significance of monoclonal gammopathies (MGUS): First results of the nomoremgus study

Marta Lasa, Esperanza Martin-Sanchez, Aintzane Zabaleta, Diego Alignani, Carmen Gonzalez, Noemi Puig, Elena Alejo, Jorge Labrador, Maria Casanova Espinosa, Laura Rosiñol Dachs, Sebastián Garzón, Enrique Ocio, Albert Pérez-Montaña, Irene Romera, Carmen Couto, Sunil Lakhwani, Felipe Prosper, Adrian Alegre, Elena Cabezudo, Itziar Carro, Cristina Motlló, Montserrat Cortes, Isabel Maria Garcia Cabrera, Marta Romera, Javier de la Rubia, Andrea Manubens, Alexia Suarez Cabrera, Fernando Escalante Barrigón, Carlos Aguilar-Franco, Raquel Del Campo, Maria Esther Clavero Sanchez, Joaquin Martinez-Lopez, Valentin Cabanas Perianes, María-Jesús Blanchard, Ana Lopez-Guia, Diana Sanchez Arguello, Albert Oriol, Marta Reinoso -Segura, María Lourdes Amador Barciela, Celina Benavente Cuesta, Jose Maria Arguiñano PEREZ, Beatriz Ordoñez, Francisco Taboada, Joan Batista Blade Creixenti, María-Victoria Mateos, Juan-Jose Lahuerta Palacios, Jesus San-Miguel, Bruno Paiva

Blood (2025) 146 (Supplement 1): 578.

https://doi.org/10.1182/blood-2025-578

Published: 2025

Journal Articles

Single-cell transcriptomics reveal long non-coding RNA dysregulation in PPP1R15B-EIF2A axis impairing erythroid maturation in myelodysplastic syndromes

Francisco Beas, Enrique Goñi, Aintzane Diaz-Mazkiaran, Teresa Ezponda, Ana Alfonso-Pierola, Andres Jerez, Felipe Prosper, David Valcarcel, Mikel Hernáez Arrazola

Blood (2025) 146 (Supplement 1): 2056.

https://doi.org/10.1182/blood-2025-2056

Published: 2025

Journal Articles

Transcriptional stratification reveals distinct molecular subtypes with treatment-specific outcomes in multiple myeloma patients from the GEM2017FIT trial

Blood (2025) 146 (Supplement 1): 496.

https://doi.org/10.1182/blood-2025-496

Published: 2025

Journal Articles

Circulating tumor cells (CTCs) for dynamic risk assessment of patients (Pts) with smoldering multiple myeloma (SMM)

Blood (2025) 146 (Supplement 1): 493.

https://doi.org/10.1182/blood-2025-493

Published: 2025

Journal Articles

FAM46C/Tent5c inactivation accelerates multiple myeloma progression from early stages and remodels the bone marrow immune microenvironment in preclinical models

Blood (2025) 146 (Supplement 1): 1027.

https://doi.org/10.1182/blood-2025-1027

Published: 2025

Journal Articles

Single-cell DNA profiling unveils clonal evolution and identifies mechanisms of therapeutic resistance and progression in monoclonal gammopathies

Beñat Ariceta, Paula Aguirre-Ruiz, Andrea Castro, Diego Alignani, Saioa Vicente, Aitziber Lopez, Ana Alfonso-Pierola, Luis-Esteban Tamariz-Amador, Jesus San-Miguel, Paula Rodriguez-Otero, Felipe Prosper

Blood (2025) 146 (Supplement 1): 7445.

https://doi.org/10.1182/blood-2025-7445

Published: 2025

Journal Articles

Targeted long-read sequencing with adaptive sampling in multiple myeloma: A pilot study toward a unified diagnostic platform

Beñat Ariceta, Paula Aguirre-Ruiz, Andrea Castro, Patxi San Martin-Uriz, Saioa Vicente, Maria Jose Larrayoz, Luis-Esteban Tamariz-Amador, Ana Alfonso-Pierola, Jesus San-Miguel, Maria Calasanz, Paula Rodriguez-Otero, Felipe Prosper

Blood (2025) 146 (Supplement 1): 6121.

https://doi.org/10.1182/blood-2025-6121

Published: 2025

Journal Articles

Absence of circulating tumor cells (CTCs) defines a subtype of multiple myeloma (MM) patients (Pts) with unique clinical and biological features

Blood (2025) 146 (Supplement 1): 366.

https://doi.org/10.1182/blood-2025-366

Published: 2025

Journal Articles

The point-of-care network with the BCMA-directed CART ARI0002h (Cesnicabtagene Autoleucel) in patients with relapsed/refractory multiple myeloma maintains efficacy and safety in real-world data

Blood (2025) 146 (Supplement 1): 135.

https://doi.org/10.1182/blood-2025-135

Published: 2025

Journal Articles

Single-cell multiomic dissection of human hematopoietic stem cells reveals novel transcriptional fingerprints and regulatory programs in bone marrow and mobilized peripheral blood

Blood (2025) 146 (Supplement 1): 1377.

https://doi.org/10.1182/blood-2025-1377

Published: 2025

Journal Articles

A functional CAR-T cell atlas to unravel regulatory mechanisms of CAR-T therapies

Sergio Camara-Peña, Paula Rodriguez Marquez, Nuria Planell, Maria Erendira Calleja-Cervantes, Lorea Jordana-Urriza, Giacomo Cinnirella, Shlomit Reich-Zeliger, Nir Yosef, Idoia Ochoa, Juan Roberto Rodriguez-Madoz, Mikel Hernáez Arrazola, Felipe Prosper

Blood (2025) 146 (Supplement 1): 5889.

https://doi.org/10.1182/blood-2025-5889

Published: 2025

Journal Articles

Integrated single-cell and spatial analysis identifies T cell exhaustion and adhesion signatures in early follicular lymphoma transformation

Blood (2025) 146 (Supplement 1): 3539.

https://doi.org/10.1182/blood-2025-3539

Published: 2025

Journal Articles

Virma epitranscriptomically regulates cell proliferation, apoptosis, and mitochondrial function via m6A in multiple myeloma

Estibaliz Urizar Compains, Naroa Barrena, Theodore Maximilian Nelson, Leire Garate, Estibaliz Miranda Elizalde, Juan Antonio Romero Torrecilla, Luis Vitores Valcárcel García, Marta Kulis, Elisa Garbayo Atienza, Maria José Blanco Prieto, Paula Rodriguez-Otero, Jose Martin-Subero, Christopher Mason, Edurne San José Enériz, Felipe Prosper, Xabier Agirre

Blood (2025) 146 (Supplement 1): 3255.

https://doi.org/10.1182/blood-2025-3255

Published: 2025

Journal Articles

“Linc-ing” RNA isoforms to function in multiple myeloma

Xabier Agirre, Felipe Prósper

Blood (2025) 146 (7): 773–774.

https://doi.org/10.1182/blood.2025029743

Published: 2025

Journal Articles

Forimtamig, a novel GPRC5D-targeting T-cell bispecific antibody with a 2+1 format, for the treatment of multiple myeloma

Blood (2025) 145 (2): 202–219.

https://doi.org/10.1182/blood.2024025987

Published: 2025

Includes: Supplemental data

Journal Articles

Single-Cell Multiomics Data-Driven Measurable Residual Disease (MRD) Assessment Using Multidimensional Flow Cytometry (MFC) in Acute Myeloid Leukemia (AML)

Blood (2024) 144 (Supplement 1): 4328.

https://doi.org/10.1182/blood-2024-203076

Published: 2024

Journal Articles

An IFNγ-Mediated Immune Inflamed Microenvironment State in Multiple Myeloma with TP53 Loss That Can be Therapeutically Exploited

Blood (2024) 144 (Supplement 1): 670.

https://doi.org/10.1182/blood-2024-194041

Published: 2024

Journal Articles

Identification and Evaluation of Novel Sdab-Based CAR-T Cells Against BCMA with Improved Therapeutic Efficacy for Multiple Myeloma

Vianca Ibarra-Garcia, Eva Molina, Franco Bernasconi-Bisio, Federica Rochira, Saray Rodríguez Diaz, Rebeca Martínez Turrillas, Paula Rodriguez-Marquez, Patricia Jauregui, Lucia Vanrell, Sara Villar, Paula Rodríguez-Otero, Juan J Lasarte, Juan Roberto Rodriguez-Madoz, Felipe Prosper, Antonio Pineda-Lucena

Blood (2024) 144 (Supplement 1): 7155.

https://doi.org/10.1182/blood-2024-208103

Published: 2024

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Reprogramming glutamine metabolism enhances BCMA -CAR T-cell fitness and therapeutic efficacy in multiple myeloma

Innovative sdab-based CAR-T cells targeting BCMA outperform current CAR-T therapies for multiple myeloma

Ending the undetermined significance of monoclonal gammopathies (MGUS): First results of the nomoremgus study

Single-cell transcriptomics reveal long non-coding RNA dysregulation in PPP1R15B-EIF2A axis impairing erythroid maturation in myelodysplastic syndromes

Transcriptional stratification reveals distinct molecular subtypes with treatment-specific outcomes in multiple myeloma patients from the GEM2017FIT trial

Circulating tumor cells (CTCs) for dynamic risk assessment of patients (Pts) with smoldering multiple myeloma (SMM)

FAM46C/Tent5c inactivation accelerates multiple myeloma progression from early stages and remodels the bone marrow immune microenvironment in preclinical models

Single-cell DNA profiling unveils clonal evolution and identifies mechanisms of therapeutic resistance and progression in monoclonal gammopathies

Targeted long-read sequencing with adaptive sampling in multiple myeloma: A pilot study toward a unified diagnostic platform

Absence of circulating tumor cells (CTCs) defines a subtype of multiple myeloma (MM) patients (Pts) with unique clinical and biological features

The point-of-care network with the BCMA-directed CART ARI0002h (Cesnicabtagene Autoleucel) in patients with relapsed/refractory multiple myeloma maintains efficacy and safety in real-world data

Single-cell multiomic dissection of human hematopoietic stem cells reveals novel transcriptional fingerprints and regulatory programs in bone marrow and mobilized peripheral blood

A functional CAR-T cell atlas to unravel regulatory mechanisms of CAR-T therapies

Integrated single-cell and spatial analysis identifies T cell exhaustion and adhesion signatures in early follicular lymphoma transformation

Virma epitranscriptomically regulates cell proliferation, apoptosis, and mitochondrial function via m6A in multiple myeloma

“Linc-ing” RNA isoforms to function in multiple myeloma

Forimtamig, a novel GPRC5D-targeting T-cell bispecific antibody with a 2+1 format, for the treatment of multiple myeloma

Single-Cell Multiomics Data-Driven Measurable Residual Disease (MRD) Assessment Using Multidimensional Flow Cytometry (MFC) in Acute Myeloid Leukemia (AML)

An IFNγ-Mediated Immune Inflamed Microenvironment State in Multiple Myeloma with TP53 Loss That Can be Therapeutically Exploited

Identification and Evaluation of Novel Sdab-Based CAR-T Cells Against BCMA with Improved Therapeutic Efficacy for Multiple Myeloma

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