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Journal Articles

RG6234, a GPRC5DxCD3 T-Cell Engaging Bispecific Antibody, Is Highly Active in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM): Updated Intravenous (IV) and First Subcutaneous (SC) Results from a Phase I Dose-Escalation Study

Carmelo Carlo-Stella, Rita Mazza, Salomon Manier, Thierry Facon, Sung-Soo Yoon, Youngil Koh, Simon J Harrison, Jeremy Er, Antonio Pinto, Francesco Volzone, Giulia Perrone, Paolo Corradini, Titouan Cazaubiel, Cyrille Hulin, Cyrille Touzeau, Philippe Moreau, Enrique M. Ocio, Carmen Maria Montes Gaisan, Rakesh Popat, Sarah Leong, Fritz Offner, Paula Rodriguez Otero, Ana Alfonso-Pierola, Ann-Marie E Bröske, Iryna Dekhtiarenko, Hans-Joachim Helms, Sara Belli, Eva Rossmann, Tanja Fauti, Jan Eckmann, Tom Moore, Meike Schneider, Wolfgang Jacob, Martin Weisser, Martin Hutchings, Caroline Hasselbalch Riley
Journal: Blood
Blood (2022) 140 (Supplement 1): 397–399.
https://doi.org/10.1182/blood-2022-157988
Published: 2022
Journal Articles

RG6234: A Novel 2:1 GPRC5D T Cell Bispecific Antibody Exhibits Best in Class Potential for the Treatment of Multiple Myeloma As a Monotherapy and in Combination

Jan Eckmann, Tanja Fauti, Aintzane Zabaleta, Laura Blanco, Sahar Kassem, Nadege Carrié, Stefan Lorenz, Alejandro Carpy, Tony Christopeit, Georg Fertig, Luise Bernasconi, Marlene Biehl, Sarah Diggelmann, Melanie Knobloch, Maud Mayoux, Charles Dumontet, Bruno Paiva, Ludovic Martinet, Stéphane Leclair, Wei Xu, Christian Klein, Pablo Umaña
Journal: Blood
Blood (2022) 140 (Supplement 1): 2091–2092.
https://doi.org/10.1182/blood-2022-157485
Published: 2022
Journal Articles

A New Class of T-Cell Bispecific Antibodies for the Treatment of Multiple Myeloma, Binding to B Cell Maturation Antigen and CD3 and Showing Potent, Specific Antitumor Activity in Myeloma Cells and Long Duration of Action in Cynomolgus Monkeys

Minh Diem Vu, PhD, Samuel Moser, MSc, Camille Delon, MSc, Melanie Latzko, MSc, Reto Gianotti, MSc, Remo Lüoend, BSc, Chloé Friang, MSc, Ramona Murr, MSc, Lydia Jasmin Duerner, PhD, Tina Weinzierl, PhD, Tanja Fauti, PhD, Marina Bacac, PhD, Oliver Ast, PhD, Anne Freimoser-Grundschober, PhD, Tea Rodriguez Diaz, MSc, Jörg Zielonka, PhD, Erwin van Puijenbroek, PhD, Ralf Hosse, PhD, Peter Bruenker, PhD, Ekkehard Mössner, PhD, Christian Klein, PhD, Pablo Umaña, PhD, Klaus Strein, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2998.
https://doi.org/10.1182/blood.V126.23.2998.2998
Published: 2015