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Issue Archive

Volume 133, Issue 10
March 7 2019
Issue Cover

Table of Contents

EDITORIAL

Introduction to a review series on myelodysplastic syndromes
Clinical Trials & Observations
Bob Löwenberg
View Articletitled, Introduction to a review series on myelodysplastic syndromes

BLOOD COMMENTARIES

CLINICAL TRIALS AND OBSERVATIONS
Targeting CD20 takes the backseat in CLL
Clinical Trials & Observations
John C. Byrd
View Articletitled, Targeting CD20 takes the backseat in CLL
Lymphoid Neoplasia
Genetic susceptibility to breast cancer in lymphoma survivors
James M. Allan
View Articletitled, Genetic susceptibility to breast cancer in lymphoma survivors
MYELOID NEOPLASIA
More than a fusion gene: the RUNX1-RUNX1T1 AML
Torsten Haferlach,Manja Meggendorfer
View Articletitled, More than a fusion gene: the <em>RUNX1</em>-<em>RUNX1T1</em> AML
THROMBOSIS AND HEMOSTASIS
Heavy chain of FXII: not an innocent bystander!
Helen Philippou
View Articletitled, Heavy chain of FXII: not an innocent bystander!

PLENARY PAPER

CLINICAL TRIALS AND OBSERVATIONS
Randomized trial of ibrutinib vs ibrutinib plus rituximab in patients with chronic lymphocytic leukemia
Clinical Trials & Observations
Jan A. Burger,Mariela Sivina,Nitin Jain,Ekaterina Kim,Tapan Kadia,Zeev Estrov,Graciela M. Nogueras-Gonzalez,Xuelin Huang,Jeffrey Jorgensen,Jianling Li,Mei Cheng,Fong Clow,Maro Ohanian,Michael Andreeff,Thomas Mathew,Philip Thompson,Hagop Kantarjian,Susan O’Brien,William G. Wierda,Alessandra Ferrajoli,Michael J. Keating

There is a Blood Commentary on this article in this issue.

View Articletitled, Randomized trial of ibrutinib vs ibrutinib plus rituximab in patients with chronic lymphocytic leukemia
Supplemental data

SPECIAL REPORT

Proposals for revised IWG 2018 hematological response criteria in patients with MDS included in clinical trials
Clinical Trials & Observations
U. Platzbecker,P. Fenaux,L. Adès,A. Giagounidis,V. Santini,A. A. van de Loosdrecht,D. Bowen,T. de Witte,G. Garcia-Manero,E. Hellström-Lindberg,U. Germing,R. Stauder,L. Malcovati,Mikkael A. Sekeres,David P. Steensma,S. Gloaguen
View Articletitled, Proposals for revised IWG 2018 hematological response criteria in patients with MDS included in clinical trials

REVIEW SERIES

The mesenchymal niche in MDS
Eline Pronk,Marc H. G. P. Raaijmakers
View Articletitled, The mesenchymal niche in MDS
The central role of inflammatory signaling in the pathogenesis of myelodysplastic syndromes
David A. Sallman,Alan List
View Articletitled, The central role of inflammatory signaling in the pathogenesis of myelodysplastic syndromes
Genetics of MDS
Clinical Trials & Observations
Seishi Ogawa
View Articletitled, Genetics of MDS
Juvenile myelomonocytic leukemia: who’s the driver at the wheel?
Clinical Trials & Observations
Charlotte M. Niemeyer,Christian Flotho
View Articletitled, Juvenile myelomonocytic leukemia: who’s the driver at the wheel?
Genetic predisposition to MDS: clinical features and clonal evolution
Clinical Trials & Observations
Alyssa L. Kennedy,Akiko Shimamura
View Articletitled, Genetic predisposition to MDS: clinical features and clonal evolution
MDS overlap disorders and diagnostic boundaries
Clinical Trials & Observations
Tiffany N. Tanaka,Rafael Bejar
View Articletitled, MDS overlap disorders and diagnostic boundaries
Treatment of MDS
Clinical Trials & Observations
Uwe Platzbecker
View Articletitled, Treatment of MDS

HEMATOPOIESIS AND STEM CELLS

MHC class II cell-autonomously regulates self-renewal and differentiation of normal and malignant B cells
Julia Merkenschlager,Urszula Eksmond,Luca Danelli,Jan Attig,George R. Young,Carla Nowosad,Pavel Tolar,George Kassiotis
View Articletitled, MHC class II cell-autonomously regulates self-renewal and differentiation of normal and malignant B cells
Supplemental data

LYMPHOID NEOPLASIA

Single-cell RNA-Seq of follicular lymphoma reveals malignant B-cell types and coexpression of T-cell immune checkpoints
Noemi Andor,Erin F. Simonds,Debra K. Czerwinski,Jiamin Chen,Susan M. Grimes,Christina Wood-Bouwens,Grace X. Y. Zheng,Matthew A. Kubit,Stephanie Greer,William A. Weiss,Ronald Levy,Hanlee P. Ji
View Articletitled, Single-cell RNA-Seq of follicular lymphoma reveals malignant B-cell types and coexpression of T-cell immune checkpoints
Supplemental data
Genetic susceptibility to radiation-induced breast cancer after Hodgkin lymphoma
Annemieke W. J. Opstal-van Winden,Hugoline G. de Haan,Michael Hauptmann,Marjanka K. Schmidt,Annegien Broeks,Nicola S. Russell,Cécile P. M. Janus,Augustinus D. G. Krol,Frederieke H. van der Baan,Marie L. De Bruin,Anna M. van Eggermond,Joe Dennis,Hoda Anton-Culver,Christopher A. Haiman,Elinor J. Sawyer,Angela Cox,Peter Devilee,Maartje J. Hooning,Julian Peto,Fergus J. Couch,Paul Pharoah,Nick Orr,Douglas F. Easton,Berthe M. P. Aleman,Louise C. Strong,Smita Bhatia,Rosie Cooke,Leslie L. Robison,Anthony J. Swerdlow,Flora E. van Leeuwen

There is a Blood Commentary on this article in this issue.

View Articletitled, Genetic susceptibility to radiation-induced breast cancer after Hodgkin lymphoma
Supplemental data

MYELOID NEOPLASIA

Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients
Friederike Christen,Kaja Hoyer,Kenichi Yoshida,Hsin-An Hou,Nils Waldhueter,Michael Heuser,Robert K. Hills,Willy Chan,Raphael Hablesreiter,Olga Blau,Yotaro Ochi,Piroska Klement,Wen-Chien Chou,Igor-Wolfgang Blau,Jih-Luh Tang,Tomasz Zemojtel,Yuichi Shiraishi,Yusuke Shiozawa,Felicitas Thol,Arnold Ganser,Bob Löwenberg,David C. Linch,Lars Bullinger,Peter J. M. Valk,Hwei-Fang Tien,Rosemary E. Gale,Seishi Ogawa,Frederik Damm
View Articletitled, Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients
Supplemental data

THROMBOSIS AND HEMOSTASIS

A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain
Ivan Ivanov,Anton Matafonov,Mao-fu Sun,Bassem M. Mohammed,Qiufang Cheng,S. Kent Dickeson,Suman Kundu,Ingrid M. Verhamme,Andras Gruber,Keith McCrae,David Gailani
View Articletitled, A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain
Supplemental data

BLOOD WORK

Nuclear protrusion in dysplastic micromegakaryocytes
Laura Pérez-Ortega,Rosario M. Morales-Camacho
View Articletitled, Nuclear protrusion in dysplastic micromegakaryocytes
Lamotrigine-associated hemophagocytic lymphohistiocytosis
Christie L. Hancock,Angel Gálvez
View Articletitled, Lamotrigine-associated hemophagocytic lymphohistiocytosis
All Issues

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Data mining for second malignancies after CAR-T
Silva A, Almeida ARM, Cachucho A, et al. Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma. Blood. 2021;138(12):1040-1052.
MRD and EFS in pediatric T-lymphoblastic lymphoma
Outcomes of younger patients with mantle-cell lymphoma experiencing late relapse (>24 months): the LATE-POD study
Mutational profile of previously treated chronic lymphocytic leukemia patients progressing on acalabrutinib or ibrutinib

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