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Issue Archive

Volume 124, Issue 3
July 17 2014
Issue Cover

Table of Contents

EDITORIAL

Introduction to the Review Series on “Advances in Hematopoietic Cell Transplantation”
Robert S. Negrin
View Articletitled, Introduction to the Review Series on “Advances in Hematopoietic Cell Transplantation”

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
Triple jeopardy for Hodgkin lymphoma survivors?
Lindsay M. Morton
View Articletitled, Triple jeopardy for Hodgkin lymphoma survivors?
INSIDE BLOOD COMMENTARY
Targeted diphtheria toxin to treat BPDCN
Clinical Trials & Observations
David J. FitzGerald
View Articletitled, Targeted diphtheria toxin to treat BPDCN
INSIDE BLOOD COMMENTARY
Pearson syndrome in a Diamond-Blackfan anemia cohort
Blanche P. Alter
View Articletitled, Pearson syndrome in a Diamond-Blackfan anemia cohort
INSIDE BLOOD COMMENTARY
FVIII stabilization: VWF D′D3 will do
Laura L. Swystun,David Lillicrap
View Articletitled, FVIII stabilization: VWF D′D3 will do

BLOOD WORK

Spontaneous splenic rupture in mantle cell lymphoma with leukemic variant
Shahzad Raza,Donald C. Doll
View Articletitled, Spontaneous splenic rupture in mantle cell lymphoma with leukemic variant
Magic mirror in my hand, which is the lineage in the end? A case of acute leukemia with hand-mirror cells
Alex Freire Sandes,Edgar Gil Rizzatti
View Articletitled, Magic mirror in my hand, which is the lineage in the end? A case of acute leukemia with hand-mirror cells

PLENARY PAPER

Risk of multiple primary malignancies following treatment of Hodgkin lymphoma
CME
Anna M. van Eggermond,Michael Schaapveld,Pieternella J. Lugtenburg,Augustinus D. G. Krol,Jan Paul de Boer,Josée M. Zijlstra,John M. M. Raemaekers,Leontien C. M. Kremer,Judith M. Roesink,Marieke W. J. Louwman,Berthe M. P. Aleman,Flora E. van Leeuwen
View Articletitled, Risk of multiple primary malignancies following treatment of Hodgkin lymphoma
Supplemental data

BLOOD SPOTLIGHT

The future of autologous stem cell transplantation in myeloma
Clinical Trials & Observations
Frits van Rhee,Sergio Giralt,Bart Barlogie
View Articletitled, The future of autologous stem cell transplantation in myeloma

REVIEW SERIES

Hematopoietic stem cell transplantation donor sources in the 21st century: choosing the ideal donor when a perfect match does not exist
Natasha Kekre,Joseph H. Antin
View Articletitled, Hematopoietic stem cell transplantation donor sources in the 21st century: choosing the ideal donor when a perfect match does not exist

REVIEW SERIES

Conditioning regimens for hematopoietic cell transplantation: one size does not fit all
Boglarka Gyurkocza,Brenda M. Sandmaier
View Articletitled, Conditioning regimens for hematopoietic cell transplantation: one size does not fit all

REVIEW SERIES

The biology of graft-versus-host disease: experimental systems instructing clinical practice
Kate A. Markey,Kelli P. A. MacDonald,Geoffrey R. Hill
View Articletitled, The biology of graft-versus-host disease: experimental systems instructing clinical practice

REVIEW SERIES

Acute graft-versus-host disease: a bench-to-bedside update
Shernan G. Holtan,Marcelo Pasquini,Daniel J. Weisdorf
View Articletitled, Acute graft-versus-host disease: a bench-to-bedside update

REVIEW SERIES

Current issues in chronic graft-versus-host disease
Gérard Socié,Jerome Ritz
View Articletitled, Current issues in chronic graft-versus-host disease

CLINICAL TRIALS AND OBSERVATIONS

Activity of SL-401, a targeted therapy directed to interleukin-3 receptor, in blastic plasmacytoid dendritic cell neoplasm patients
Clinical Trials & Observations
Arthur E. Frankel,Jung H. Woo,Chul Ahn,Naveen Pemmaraju,Bruno C. Medeiros,Hetty E. Carraway,Olga Frankfurt,Stephen J. Forman,Xuezhong A. Yang,Marina Konopleva,Francine Garnache-Ottou,Fanny Angelot-Delettre,Christopher Brooks,Michael Szarek,Eric Rowinsky
View Articletitled, Activity of SL-401, a targeted therapy directed to interleukin-3 receptor, in blastic plasmacytoid dendritic cell neoplasm patients

HEMATOPOIESIS AND STEM CELLS

BMP signaling balances murine myeloid potential through SMAD-independent p38MAPK and NOTCH pathways
Brandoch D. Cook,Todd Evans
View Articletitled, BMP signaling balances murine myeloid potential through SMAD-independent p38MAPK and NOTCH pathways
Supplemental data

IMMUNOBIOLOGY

Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation
Shiguo Zhu,Prasad V. Phatarpekar,Cecele J. Denman,Vladimir V. Senyukov,Srinivas S. Somanchi,Hoainam T. Nguyen-Jackson,Emily M. Mace,Alexandra F. Freeman,Stephanie S. Watowich,Jordan S. Orange,Steven M. Holland,Dean A. Lee
View Articletitled, Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation

LYMPHOID NEOPLASIA

B-cell prolymphocytic leukemia: a specific subgroup of mantle cell lymphoma
Vincent H. J. van der Velden,Patricia G. Hoogeveen,Dick de Ridder,Magdalena Schindler-van der Struijk,Menno C. van Zelm,Mathijs Sanders,Dennis Karsch,H. Berna Beverloo,King Lam,Alberto Orfao,Pieternella J. Lugtenburg,Sebastian Böttcher,Jacques J. M. van Dongen,Anton W. Langerak,Mies Kappers-Klunne,Kirsten van Lom
View Articletitled, B-cell prolymphocytic leukemia: a specific subgroup of mantle cell lymphoma
Supplemental data
PTK2 expression and immunochemotherapy outcome in chronic lymphocytic leukemia
Martin Weisser,Ru-Fang Yeh,Guillemette Duchateau-Nguyen,Giuseppe Palermo,Tri Quang Nguyen,Xiaoyan Shi,Susanna Y. Stinson,Nancy Yu,Annika Dufour,Tadeusz Robak,Galina N. Salogub,Anna Dmoszynska,Philippe Solal-Celigny,Krzysztof Warzocha,Javier Loscertales,John Catalano,Loree Larratt,Viktor A. Rossiev,Isabelle Bence-Bruckler,Christian H. Geisler,Marco Montillo,Kirsten Fischer,Anna-Maria Fink,Michael Hallek,Johannes Bloehdorn,Raymonde Busch,Axel Benner,Hartmut Döhner,Nancy Valente,Michael K. Wenger,Stephan Stilgenbauer,David Dornan
View Articletitled, <em>PTK2</em> expression and immunochemotherapy outcome in chronic lymphocytic leukemia
Supplemental data

MYELOID NEOPLASIA

NrasG12D oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis
Liting Xue,John A. Pulikkan,Peter J. M. Valk,Lucio H. Castilla
View Articletitled, Nras<sup>G12D</sup> oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Pearson marrow pancreas syndrome in patients suspected to have Diamond-Blackfan anemia
Brief Report
Katelyn E. Gagne,Roxanne Ghazvinian,Daniel Yuan,Rebecca L. Zon,Kelsie Storm,Magdalena Mazur-Popinska,Laura Andolina,Halina Bubala,Sydonia Golebiowska,Meghan A. Higman,Krzysztof Kalwak,Peter Kurre,Michal Matysiak,Edyta Niewiadomska,Salley Pels,Mary Jane Petruzzi,Aneta Pobudejska-Pieniazek,Tomasz Szczepanski,Mark D. Fleming,Hanna T. Gazda,Suneet Agarwal
View Articletitled, Pearson marrow pancreas syndrome in patients suspected to have Diamond-Blackfan anemia
Supplemental data
Matriptase-2 is essential for hepcidin repression during fetal life and postnatal development in mice to maintain iron homeostasis
Brief Report
Alexandra Willemetz,Anne Lenoir,Jean-Christophe Deschemin,Carlos Lopez-Otin,Andrew J. Ramsay,Sophie Vaulont,Gaël Nicolas
View Articletitled, Matriptase-2 is essential for hepcidin repression during fetal life and postnatal development in mice to maintain iron homeostasis
Supplemental data

THROMBOSIS AND HEMOSTASIS

A von Willebrand factor fragment containing the D′D3 domains is sufficient to stabilize coagulation factor VIII in mice
Andrew Yee,Robert D. Gildersleeve,Shufang Gu,Colin A. Kretz,Beth M. McGee,Keisha M. Carr,Steven W. Pipe,David Ginsburg
View Articletitled, A von Willebrand factor fragment containing the D′D3 domains is sufficient to stabilize coagulation factor VIII in mice
Supplemental data

TRANSPLANTATION

Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia
Mohini Rajasagi,Sachet A. Shukla,Edward F. Fritsch,Derin B. Keskin,David DeLuca,Ellese Carmona,Wandi Zhang,Carrie Sougnez,Kristian Cibulskis,John Sidney,Kristen Stevenson,Jerome Ritz,Donna Neuberg,Vladimir Brusic,Stacey Gabriel,Eric S. Lander,Gad Getz,Nir Hacohen,Catherine J. Wu
View Articletitled, Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia
Supplemental data

ERRATA

Zonios DI, Falloon J, Bennett JE, et al. Idiopathic CD4+ lymphocytopenia: natural history and prognostic factors. Blood. 2008;112(2):287-294.
View Articletitled, Zonios DI, Falloon J, Bennett JE, et al. Idiopathic CD4<sup>+</sup> lymphocytopenia: natural history and prognostic factors. <em>Blood</em>. 2008;112(2):<span class="related-article">287-294</span>.
Buglio D, Palakurthi S, Byth K, et al. Essential role of TAK1 in regulating mantle cell lymphoma survival. Blood. 2012;120(2):347-355.
View Articletitled, Buglio D, Palakurthi S, Byth K, et al. Essential role of TAK1 in regulating mantle cell lymphoma survival. <em>Blood.</em> 2012;120(2):<span class="related-article">347-355</span>.
Buglio D, Khaskhely NM, Voo KS, Martinez-Valdez H, Liu Y-J, Younes A. HDAC11 plays an essential role in regulating OX40 ligand expression in Hodgkin lymphoma. Blood. 2011;117(10):2910-2917.
View Articletitled, Buglio D, Khaskhely NM, Voo KS, Martinez-Valdez H, Liu Y-J, Younes A. HDAC11 plays an essential role in regulating OX40 ligand expression in Hodgkin lymphoma. <em>Blood</em>. 2011;117(10):<span class="related-article">2910-2917</span>.

CONTINUING MEDICAL EDUCATION (CME) QUESTIONS

Multiple malignancies after Hodgkin lymphoma
CME
View Articletitled, Multiple malignancies after Hodgkin lymphoma
  • Cover Image

    Cover Image

    issue cover

    Fluorescence in situ hybridization of mitochondrial DNA (mtDNA) in fibroblasts from a patient with Pearson syndrome. A green probe corresponding to the intact region of the mtDNA and a red probe corresponding to the deleted region of mtDNA are simultaneously hybridized. The image shows heterogeneity of signals in the population, reflecting heteroplasmy, and also reveals the striking example of a cell containing almost entirely deleted mtDNA. See the article by Gagne et al on page 437.

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