Annemiek Broyl,for the Dutch-Belgian HOVON group and the German GMMG Group,Rowan Kuiper,for the Dutch-Belgian HOVON group and the German GMMG Group,Mark van Duin,for the Dutch-Belgian HOVON group and the German GMMG Group,Bronno van der Holt,for the Dutch-Belgian HOVON group and the German GMMG Group,Laila el Jarari,for the Dutch-Belgian HOVON group and the German GMMG Group,Uta Bertsch,for the Dutch-Belgian HOVON group and the German GMMG Group,Sonja Zweegman,for the Dutch-Belgian HOVON group and the German GMMG Group,Arjan Buijs,for the Dutch-Belgian HOVON group and the German GMMG Group,Dirk Hose,for the Dutch-Belgian HOVON group and the German GMMG Group,Henk M. Lokhorst,for the Dutch-Belgian HOVON group and the German GMMG Group,Hartmut Goldschmidt,for the Dutch-Belgian HOVON group and the German GMMG Group,Pieter Sonneveld,for the Dutch-Belgian HOVON group and the German GMMG Group

View Articletitled, High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance

Supplemental data

SPIB, a novel immunohistochemical marker for human blastic plasmacytoid dendritic cell neoplasms: characterization of its expression in major hematolymphoid neoplasms
Brief Report

Santiago Montes-Moreno,Rocio Ramos-Medina,Azahara Martínez-López,Carlos Barrionuevo Cornejo,Alejandro Parra Cubillos,Shirley Quintana-Truyenque,Socorro María Rodriguez Pinilla,Raquel Pajares,Lydia Sanchez-Verde,Jorge Martinez-Torrecuadrada,Giovanna Roncador,Miguel Angel Piris

View Articletitled, SPIB, a novel immunohistochemical marker for human blastic plasmacytoid dendritic cell neoplasms: characterization of its expression in major hematolymphoid neoplasms

Supplemental data

Myeloid Neoplasia

The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia

Athina Giannoudis,Lihui Wang,Andrea L. Jorgensen,George Xinarianos,Andrea Davies,Sudeep Pushpakom,Triantafilos Liloglou,Jieying-Eunice Zhang,Gemma Austin,Tessa L. Holyoake,Letizia Foroni,Panagiotis D. Kottaridis,Martin C. Müller,Munir Pirmohamed,Richard E. Clark

View Articletitled, The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia

Supplemental data

The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis
Brief Report

Yasuhiko Kamikubo,R. Katherine Hyde,Ling Zhao,Lemlem Alemu,Cecilia Rivas,Lisa J. Garrett,P. Paul Liu

View Articletitled, The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis

Supplemental data

Platelets and Thrombopoiesis

Impaired thrombin-induced platelet activation and thrombus formation in mice lacking the Ca²⁺-dependent tyrosine kinase Pyk2

Ilaria Canobbio,Lina Cipolla,Alessandra Consonni,Stefania Momi,Gianni Guidetti,Barbara Oliviero,Marco Falasca,Mitsuhiko Okigaki,Cesare Balduini,Paolo Gresele,Mauro Torti

View Articletitled, Impaired thrombin-induced platelet activation and thrombus formation in mice lacking the Ca<sup>2+</sup>-dependent tyrosine kinase Pyk2

Red Cells, Iron, and Erythropoiesis

JAK2V617F activates Lu/BCAM-mediated red cell adhesion in polycythemia vera through an EpoR-independent Rap1/Akt pathway

Maria De Grandis,Marie Cambot,Marie-Paule Wautier,Bruno Cassinat,Christine Chomienne,Yves Colin,Jean-Luc Wautier,Caroline Le Van Kim,Wassim El Nemer

View Articletitled, JAK2V617F activates Lu/BCAM-mediated red cell adhesion in polycythemia vera through an EpoR-independent Rap1/Akt pathway

Supplemental data

EKLF-driven PIT1 expression is critical for mouse erythroid maturation in vivo and in vitro

Anne Forand,Laurent Beck,Christine Leroy,Alice Rousseau,Valérie Boitez,Isabelle Cohen,Geneviève Courtois,Olivier Hermine,Gérard Friedlander

View Articletitled, EKLF-driven <em>PIT1</em> expression is critical for mouse erythroid maturation in vivo and in vitro

Supplemental data

Thrombosis and Hemostasis

Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

Christoph Kleinschnitz,Peter Kraft,Angela Dreykluft,Ina Hagedorn,Kerstin Göbel,Michael K. Schuhmann,Friederike Langhauser,Xavier Helluy,Tobias Schwarz,Stefan Bittner,Christian T. Mayer,Marc Brede,Csanad Varallyay,Mirko Pham,Martin Bendszus,Peter Jakob,Tim Magnus,Sven G. Meuth,Yoichiro Iwakura,Alma Zernecke,Tim Sparwasser,Bernhard Nieswandt,Guido Stoll,Heinz Wiendl

View Articletitled, Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

Supplemental data

Vascular Gas6 contributes to thrombogenesis and promotes tissue factor up-regulation after vessel injury in mice

Richard S. Robins,Catherine A. Lemarié,Sandrine Laurance,Meghedi N. Aghourian,Jianqiu Wu,Mark D. Blostein

View Articletitled, Vascular Gas6 contributes to thrombogenesis and promotes tissue factor up-regulation after vessel injury in mice

Supplemental data

Structural framework of c-Src activation by integrin β3

Run Xiao,Xiao-Dong Xi,Zhu Chen,Sai-Juan Chen,Guoyu Meng

View Articletitled, Structural framework of c-Src activation by integrin β3

Supplemental data

Vascular Biology

Transcriptional repression of VEGF by ZNF24: mechanistic studies and vascular consequences in vivo

Di Jia,Sean M. Hasso,Joanne Chan,Domenic Filingeri,Patricia A. D'Amore,Lori Rice,Christine Pampo,Dietmar W. Siemann,David Zurakowski,Scott J. Rodig,Marsha A. Moses

View Articletitled, Transcriptional repression of VEGF by ZNF24: mechanistic studies and vascular consequences in vivo

Supplemental data

Cover Image

Cover Image

Transgenic zebrafish embryo harboring an endothelial cell–specific fluorescent reporter (Fli1:EGFP) reveals the normal vasculature at 30 hours after fertilization (top). Expression of ZNF24 leads to defects in intersegmental vessel formation (bottom) and abnormal formation of the caudal vascular plexus (bottom, boxed). See the article by Jia et al on page 707.
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Licking the wound with procoagulant vesicles

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Table of Contents

Inside Blood

Moving T memory stem cells to the clinic

Surprisingly variable “dangers, toils, and snares” faced by humans and mice

Gas6 gains entry into the coagulation cascade

Blood Work

Acquired elliptocytosis of myelodysplastic syndrome

Plenary Paper

IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors

Review Article

Discovery and validation of graft-versus-host disease biomarkers

Immunobiology

Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1, RAB27A, and STX11

Hemophagocytic lymphohistiocytosis in syntaxin-11–deficient mice: T-cell exhaustion limits fatal disease

Human iNKT and MAIT cells exhibit a PLZF-dependent proapoptotic propensity that is counterbalanced by XIAP

Lymphoid Neoplasia

High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance
Brief Report

SPIB, a novel immunohistochemical marker for human blastic plasmacytoid dendritic cell neoplasms: characterization of its expression in major hematolymphoid neoplasms
Brief Report

Myeloid Neoplasia

The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia

The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis
Brief Report

Platelets and Thrombopoiesis

Impaired thrombin-induced platelet activation and thrombus formation in mice lacking the Ca²⁺-dependent tyrosine kinase Pyk2

Red Cells, Iron, and Erythropoiesis

JAK2V617F activates Lu/BCAM-mediated red cell adhesion in polycythemia vera through an EpoR-independent Rap1/Akt pathway

EKLF-driven PIT1 expression is critical for mouse erythroid maturation in vivo and in vitro

Thrombosis and Hemostasis

Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

Vascular Gas6 contributes to thrombogenesis and promotes tissue factor up-regulation after vessel injury in mice

Structural framework of c-Src activation by integrin β3

Vascular Biology

Transcriptional repression of VEGF by ZNF24: mechanistic studies and vascular consequences in vivo

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American Society of Hematology

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Table of Contents

Inside Blood

Blood Work

Plenary Paper

Review Article

Immunobiology

Lymphoid Neoplasia

High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance Brief Report

SPIB, a novel immunohistochemical marker for human blastic plasmacytoid dendritic cell neoplasms: characterization of its expression in major hematolymphoid neoplasms Brief Report

Myeloid Neoplasia

The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis Brief Report

Platelets and Thrombopoiesis

Red Cells, Iron, and Erythropoiesis

Thrombosis and Hemostasis

Vascular Biology

Cover Image

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ASH Publications

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High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance
Brief Report

SPIB, a novel immunohistochemical marker for human blastic plasmacytoid dendritic cell neoplasms: characterization of its expression in major hematolymphoid neoplasms
Brief Report

The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis
Brief Report