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Transgenic zebrafish embryo harboring an endothelial cell–specific fluorescent reporter (Fli1:EGFP) reveals the normal vasculature at 30 hours after fertilization (top). Expression of ZNF24 leads to defects in intersegmental vessel formation (bottom) and abnormal formation of the caudal vascular plexus (bottom, boxed). See the article by Jia et al on page 707.
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Cardiac complete response in AL amyloidosis has similar survival to matched general population

Randomized Bendamustine-Rituximab(R) + Bortezomib Induction and R + Lenalidomide Maintenance for Mantle Cell Lymphoma

Heme induced loss of renovascular endothelial protein C receptor promotes chronic kidney disease in sickle mice

Interleukin-1 mediated hyperinflammation in XIAP-deficiency is associated with defective autophagy.

NOVEL THERAPEUTIC APPROACHES IN THALASSEMIAS, SICKLE CELL DISEASE AND OTHER RED CELL DISORDERS

Table of Contents

Inside Blood

Moving T memory stem cells to the clinic

Surprisingly variable “dangers, toils, and snares” faced by humans and mice

Gas6 gains entry into the coagulation cascade

Blood Work

Acquired elliptocytosis of myelodysplastic syndrome

Plenary Paper

IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors

Review Article

Discovery and validation of graft-versus-host disease biomarkers

Immunobiology

Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1, RAB27A, and STX11

Hemophagocytic lymphohistiocytosis in syntaxin-11–deficient mice: T-cell exhaustion limits fatal disease

Human iNKT and MAIT cells exhibit a PLZF-dependent proapoptotic propensity that is counterbalanced by XIAP

Lymphoid Neoplasia

High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance
Brief Report

SPIB, a novel immunohistochemical marker for human blastic plasmacytoid dendritic cell neoplasms: characterization of its expression in major hematolymphoid neoplasms
Brief Report

Myeloid Neoplasia

The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia

The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis
Brief Report

Platelets and Thrombopoiesis

Impaired thrombin-induced platelet activation and thrombus formation in mice lacking the Ca²⁺-dependent tyrosine kinase Pyk2

Red Cells, Iron, and Erythropoiesis

JAK2V617F activates Lu/BCAM-mediated red cell adhesion in polycythemia vera through an EpoR-independent Rap1/Akt pathway

EKLF-driven PIT1 expression is critical for mouse erythroid maturation in vivo and in vitro

Thrombosis and Hemostasis

Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

Vascular Gas6 contributes to thrombogenesis and promotes tissue factor up-regulation after vessel injury in mice

Structural framework of c-Src activation by integrin β3

Vascular Biology

Transcriptional repression of VEGF by ZNF24: mechanistic studies and vascular consequences in vivo

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ASH Publications

American Society of Hematology

Issue Archive

Table of Contents

Inside Blood

Blood Work

Plenary Paper

Review Article

Immunobiology

Lymphoid Neoplasia

High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance Brief Report

SPIB, a novel immunohistochemical marker for human blastic plasmacytoid dendritic cell neoplasms: characterization of its expression in major hematolymphoid neoplasms Brief Report

Myeloid Neoplasia

The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis Brief Report

Platelets and Thrombopoiesis

Red Cells, Iron, and Erythropoiesis

Thrombosis and Hemostasis

Vascular Biology

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ASH Publications

American Society of Hematology

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High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance
Brief Report

SPIB, a novel immunohistochemical marker for human blastic plasmacytoid dendritic cell neoplasms: characterization of its expression in major hematolymphoid neoplasms
Brief Report

The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis
Brief Report