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Bortezomib-thalidomide-dexamethasone is superior to thalidomide-dexamethasone as consolidation therapy after autologous hematopoietic stem cell transplantation in patients with newly diagnosed multiple myeloma
Management of bleeding in acquired hemophilia A: results from the European Acquired Haemophilia (EACH2) Registry
Immunosuppression for acquired hemophilia A: results from the European Acquired Haemophilia Registry (EACH2)
Long-term outcomes after autologous stem cell transplantation for patients with POEMS syndrome (osteosclerotic myeloma): a single-center experience
Issue Archive
July 5 2012
Table of Contents
Inside Blood
Blood Work
Plenary Paper
PLENARY PAPER
Bortezomib-thalidomide-dexamethasone is superior to thalidomide-dexamethasone as consolidation therapy after autologous hematopoietic stem cell transplantation in patients with newly diagnosed multiple myeloma
Clinical Trials & Observations
Michele Cavo,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Lucia Pantani,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Maria Teresa Petrucci,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Francesca Patriarca,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Elena Zamagni,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Daniela Donnarumma,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Claudia Crippa,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Mario Boccadoro,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Giulia Perrone,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Antonietta Falcone,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Chiara Nozzoli,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Renato Zambello,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Luciano Masini,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Anna Furlan,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Annamaria Brioli,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Daniele Derudas,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Stelvio Ballanti,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Maria Laura Dessanti,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Valerio De Stefano,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Angelo Michele Carella,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Magda Marcatti,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Andrea Nozza,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Felicetto Ferrara,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Vincenzo Callea,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Catello Califano,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Annalisa Pezzi,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Anna Baraldi,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Mariella Grasso,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Pellegrino Musto,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network,Antonio Palumbo,for the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto) Italian Myeloma Network
Perspectives
Review Article
Hematopoiesis and Stem Cells
Immunobiology
SAP expression in invariant NKT cells is required for cognate help to support B-cell responses
Cynthia Detre,Marton Keszei,Natividad Garrido-Mesa,Katalin Kis-Toth,Wilson Castro,Amma F. Agyemang,Natacha Veerapen,Gurdyal S. Besra,Michael C. Carroll,George C. Tsokos,Ninghai Wang,Elizabeth A. Leadbetter,Cox Terhorst
Lymphoid Neoplasia
Myeloid Neoplasia
Survivin is highly expressed in CD34+38− leukemic stem/progenitor cells and predicts poor clinical outcomes in AML
Bing Z. Carter,Yihua Qiu,Xuelin Huang,Lixia Diao,Nianxiang Zhang,Kevin R. Coombes,Duncan H. Mak,Marina Konopleva,Jorge Cortes,Hagop M. Kantarjian,Gordon B. Mills,Michael Andreeff,Steven M. Kornblau
Phagocytes, Granulocytes, and Myelopoiesis
WHIM syndrome caused by a single amino acid substitution in the carboxy-tail of chemokine receptor CXCR4
Qian Liu,Haoqian Chen,Teresa Ojode,Xiangxi Gao,Sandra Anaya-O'Brien,Nicholas A. Turner,Jean Ulrick,Rosamma DeCastro,Corin Kelly,Adela R. Cardones,Stuart H. Gold,Eugene I. Hwang,Daniel S. Wechsler,Harry L. Malech,Philip M. Murphy,David H. McDermott
Platelets and Thrombopoiesis
Thrombosis and Hemostasis
Management of bleeding in acquired hemophilia A: results from the European Acquired Haemophilia (EACH2) Registry
Clinical Trials & Observations
Francesco Baudo,on behalf of the EACH2 registry contributors,Peter Collins,on behalf of the EACH2 registry contributors,Angela Huth-Kühne,on behalf of the EACH2 registry contributors,Hervé Lévesque,on behalf of the EACH2 registry contributors,Pascual Marco,on behalf of the EACH2 registry contributors,László Nemes,on behalf of the EACH2 registry contributors,Fabio Pellegrini,on behalf of the EACH2 registry contributors,Lilian Tengborn,on behalf of the EACH2 registry contributors,Paul Knoebl,on behalf of the EACH2 registry contributors
Immunosuppression for acquired hemophilia A: results from the European Acquired Haemophilia Registry (EACH2)
Clinical Trials & Observations
Peter Collins,on behalf of the EACH2 registry collaborators,Francesco Baudo,on behalf of the EACH2 registry collaborators,Paul Knoebl,on behalf of the EACH2 registry collaborators,Hervé Lévesque,on behalf of the EACH2 registry collaborators,László Nemes,on behalf of the EACH2 registry collaborators,Fabio Pellegrini,on behalf of the EACH2 registry collaborators,Pascual Marco,on behalf of the EACH2 registry collaborators,Lilian Tengborn,on behalf of the EACH2 registry collaborators,Angela Huth-Kühne,on behalf of the EACH2 registry collaborators
Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia
Rafael H. Jácomo,Barbara A. Santana-Lemos,Ana Silvia G. Lima,Patricia A. Assis,Ana Paula A. Lange,Lorena L. Figueiredo-Pontes,Luciana O. Oliveira,Sarah C. Bassi,Mariana T. L. Benício,Márcia S. Baggio,Aglair B. Garcia,Roberto P. Falcão,Eduardo M. Rego
Transplantation
Long-term outcomes after autologous stem cell transplantation for patients with POEMS syndrome (osteosclerotic myeloma): a single-center experience
Clinical Trials & Observations
Anita D'Souza,Martha Lacy,Morie Gertz,Shaji Kumar,Francis Buadi,Suzanne Hayman,David Dingli,Steven Zeldenrust,Robert Kyle,Stephen Ansell,David Inwards,Patrick Johnston,Ivana Micallef,Luis Porrata,Mark Litzow,Dennis Gastineau,William Hogan,Angela Dispenzieri
Graft-versus-host disease disrupts intestinal microbial ecology by inhibiting Paneth cell production of α-defensins
Yoshihiro Eriguchi,Shuichiro Takashima,Hideyo Oka,Sonoko Shimoji,Kiminori Nakamura,Hidetaka Uryu,Shinji Shimoda,Hiromi Iwasaki,Nobuyuki Shimono,Tokiyoshi Ayabe,Koichi Akashi,Takanori Teshima
Vascular Biology
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Cover Image
Cover Image
Computer simulation of a plume of ADP (top) and thromboxane (middle) released from platelets depositing on collagen under hemodynamic conditions (flow streamlines and shear rate indicated in bottom panel). The intracellular calcium state of the platelets ranges from resting (black) to full activation (white) and is based upon a personalized model obtained for a single blood donor. See the article by Flamm et al on page 190.
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