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Philippe Kastner
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Journal Articles

β-Catenin activation synergizes with Pten loss and Myc overexpression in Notch-independent T-ALL

Deepika Kaveri, Philippe Kastner, Doulaye Dembélé, Claus Nerlov, Susan Chan, Peggy Kirstetter
Journal: Blood
Blood (2013) 122 (5): 694–704.
https://doi.org/10.1182/blood-2012-12-471904
Published: 2013
Includes: Supplemental data
Journal Articles

Pivotal role of plasmacytoid dendritic cells in inflammation and NK-cell responses after TLR9 triggering in mice

Camille Guillerey, Juliette Mouriès, Giulia Polo, Noelle Doyen, Helen K. W. Law, Susan Chan, Philippe Kastner, Claude Leclerc, Gilles Dadaglio
Journal: Blood
Blood (2012) 120 (1): 90–99.
https://doi.org/10.1182/blood-2012-02-410936
Published: 2012
Includes: Supplemental data
Journal Articles

Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL

Robin Jeannet, Jérôme Mastio, Alejandra Macias-Garcia, Attila Oravecz, Todd Ashworth, Anne-Solen Geimer Le Lay, Bernard Jost, Stéphanie Le Gras, Jacques Ghysdael, Thomas Gridley, Tasuku Honjo, Freddy Radtke, Jon C. Aster, Susan Chan, Philippe Kastner
Journal: Blood
Blood (2010) 116 (25): 5443–5454.
https://doi.org/10.1182/blood-2010-05-286658
Published: 2010
Includes: Supplemental data
Journal Articles

Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1

Todd D. Ashworth, Warren S. Pear, Mark Y. Chiang, Stephen C. Blacklow, Jérôme Mastio, Lanwei Xu, Michelle Kelliher, Philippe Kastner, Susan Chan, Jon C. Aster
Journal: Blood
Blood (2010) 116 (25): 5455–5464.
https://doi.org/10.1182/blood-2010-05-286328
Published: 2010
Includes: Supplemental data
Journal Articles

Deletion-Based Mechanisms of Notch1 Activation In T-ALL: Key Roles for RAG Recombinase and A Conserved Internal Translational Start Site In Notch1 .

Jon C Aster, MD, PhD, Todd D Ashworth, Mark Chiang, MD, PhD, Warren S. Pear, MD, PhD, Stephen Blacklow, Michelle Kelliher, Philippe Kastner, Susan Chan
Journal: Blood
Blood (2010) 116 (21): 3367.
https://doi.org/10.1182/blood.V116.21.3367.3367
Published: 2010
Journal Articles

Reciprocal Activation of GATA-1 and PU.1 Marks Initial Specification of Hematopoietic Stem Cells into Myelo-Erythroid and Myelo-Lymphoid Lineages.

Yojiro Arinobu, MD, PhD, Shin-ichi Mizuno, M.D., Ph.D., Yong Chong, M.D., Ph.D., Hirokazu Shigematsu, M.D., Ph.D., Tadafumi Iino, M.D., Hiromi Iwasaki, M.D., Ph.D., Thomas Graf, Ph.D., Robin Mayfield, Ph.D., Susan Chan, Ph.D., Philippe Kastner, Ph.D., Koichi Akashi, M.D., Ph.D.
Journal: Blood
Blood (2007) 110 (11): 1228.
https://doi.org/10.1182/blood.V110.11.1228.1228
Published: 2007
Journal Articles

Ikaros is required for plasmacytoid dendritic cell differentiation

David Allman, Marc Dalod, Carine Asselin-Paturel, Thomas Delale, Scott H. Robbins, Giorgio Trinchieri, Christine A. Biron, Philippe Kastner, Susan Chan
Journal: Blood
Blood (2006) 108 (13): 4025–4034.
https://doi.org/10.1182/blood-2006-03-007757
Published: 2006
Includes: Supplemental data
Journal Articles

Delineation of the Common Developmental Pathway for Granulocyte/Monocyte and Lymphoid Lineages by Using an Expression Reporter for PU.1.

Yojiro Arinobu, MD, PhD, Shin-ichi Mizuno, M.D. Ph.D., Hirokazu Shigematsu, M.D. Ph.D., Hidetoshi Ozawa, Yong Chong, M.D. Ph.D, Hiromi Iwasaki, M.D. Ph.D., Philippe Kastner, Ph.D., Susan Chan, Ph.D., Koichi Akashi, M.D. Ph.D.
Journal: Blood
Blood (2006) 108 (11): 1656.
https://doi.org/10.1182/blood.V108.11.1656.1656
Published: 2006
Journal Articles

Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation

Hiromi Iwasaki, Chamorro Somoza, Hirokazu Shigematsu, Estelle A. Duprez, Junko Iwasaki-Arai, Shin-ichi Mizuno, Yojiro Arinobu, Kristin Geary, Pu Zhang, Tajhal Dayaram, Maris L. Fenyus, Shannon Elf, Susan Chan, Philippe Kastner, Claudia S. Huettner, Richard Murray, Daniel G. Tenen, Koichi Akashi
Journal: Blood
Blood (2005) 106 (5): 1590–1600.
https://doi.org/10.1182/blood-2005-03-0860
Published: 2005
Includes: Supplemental data
Journal Articles

PU.1 determines the self-renewal capacity of erythroid progenitor cells

Jonathan Back, Andrée Dierich, Corinne Bronn, Philippe Kastner, Susan Chan
Journal: Blood
Blood (2004) 103 (10): 3615–3623.
https://doi.org/10.1182/blood-2003-11-4089
Published: 2004
Includes: Supplemental data
Journal Articles

Ikaros regulates neutrophil differentiation

Alexis Dumortier, Peggy Kirstetter, Philippe Kastner, Susan Chan
Journal: Blood
Blood (2003) 101 (6): 2219–2226.
https://doi.org/10.1182/blood-2002-05-1336
Published: 2003
Journal Articles

Positive and negative regulation of granulopoiesis by endogenous RARα

Philippe Kastner, H. Jeffrey Lawrence, Caroline Waltzinger, Norbert B. Ghyselinck, Pierre Chambon, Susan Chan
Journal: Blood
Blood (2001) 97 (5): 1314–1320.
https://doi.org/10.1182/blood.V97.5.1314
Published: 2001