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Issue Archive

Volume 6, Issue 14
July 26 2022
Issue Cover

Table of Contents

STIMULUS REPORTS

A 3-decade multicenter European experience with cladribine as upfront treatment in 384 patients with hairy cell leukemia
Clinical Trials & Observations
Alessandro Broccoli,Lisa Argnani,Matthew Cross,Agnieszka Janus,Elsa Maitre,Xavier Troussard,Tadeusz Robak,Claire Dearden,Monica Else,Daniel Catovsky,Pier Luigi Zinzani
View Articletitled, A 3-decade multicenter European experience with cladribine as upfront treatment in 384 patients with hairy cell leukemia
Supplemental data
Allelic complexity of KMT2A partial tandem duplications in acute myeloid leukemia and myelodysplastic syndromes
Harrison K. Tsai,Christopher J. Gibson,H. Moses Murdock,Phani Davineni,Marian H. Harris,Eunice S. Wang,Lukasz P. Gondek,Annette S. Kim,Valentina Nardi,R. Coleman Lindsley
View Articletitled, Allelic complexity of <em>KMT2A</em> partial tandem duplications in acute myeloid leukemia and myelodysplastic syndromes
Supplemental data
Real-world use of tisagenlecleucel in infant acute lymphoblastic leukemia
Amy Moskop,Lauren Pommert,Christina Baggott,Snehit Prabhu,Holly L. Pacenta,Christine L. Phillips,Jenna Rossoff,Heather E. Stefanski,Julie-An Talano,Steve P. Margossian,Michael R. Verneris,G. Doug Myers,Nicole A. Karras,Patrick A. Brown,Muna Qayed,Michelle L. Hermiston,Prakash Satwani,Christa Krupski,Amy K. Keating,Rachel Wilcox,Cara A. Rabik,Vanessa A. Fabrizio,Vasant Chinnabhandar,A. Yasemin Goksenin,Kevin J. Curran,Crystal L. Mackall,Theodore W. Laetsch,Erin M. Guest,Erin H. Breese,Liora M. Schultz
View Articletitled, Real-world use of tisagenlecleucel in infant acute lymphoblastic leukemia
Fatal thrombotic microangiopathy case following adeno-associated viral SMN gene therapy
Julia Guillou,Alice de Pellegars,Florence Porcheret,Véronique Frémeaux-Bacchi,Emma Allain-Launay,Camille Debord,Manon Denis,Yann Péréon,Christine Barnérias,Isabelle Desguerre,Gwenaëlle Roussey,Sandra Mercier
View Articletitled, Fatal thrombotic microangiopathy case following adeno-associated viral <em>SMN</em> gene therapy

CLINICAL TRIALS AND OBSERVATIONS

Disparities in trial enrollment and outcomes of Hispanic adolescent and young adult acute lymphoblastic leukemia
Clinical Trials & Observations
Lori Muffly,Jun Yin,Sawyer Jacobson,Anna Wall,Elisa Quiroz,Anjali S. Advani,Selina M. Luger,Martin S. Tallman,Mark R. Litzow,Matthew C. Foster,Harry P. Erba,Frederick R. Appelbaum,Richard A. Larson,Theresa H.M. Keegan,Wendy Stock
View Articletitled, Disparities in trial enrollment and outcomes of Hispanic adolescent and young adult acute lymphoblastic leukemia
Supplemental data
Total marrow and lymphoid irradiation as conditioning in haploidentical transplant with posttransplant cyclophosphamide
Clinical Trials & Observations
Monzr M. Al Malki,Joycelynne Palmer,Ni-Chun Tsai,Sally Mokhtari,Susanta Hui,Weimin Tsai,Ibrahim Aldoss,Haris Ali,Ahmed Aribi,Thai Cao,Mathew Mei,Karamjeet S. Sandhu,Tanya Siddiqi,Stephen J. Forman,Ryotaro Nakamura,Guido Marcucci,Anthony Stein,Jeffrey Y. C. Wong,Joseph Rosenthal
View Articletitled, Total marrow and lymphoid irradiation as conditioning in haploidentical transplant with posttransplant cyclophosphamide
Supplemental data
Idasanutlin plus cytarabine in relapsed or refractory acute myeloid leukemia: results of the MIRROS trial
Clinical Trials & Observations
Marina Y. Konopleva,Christoph Röllig,Jamie Cavenagh,Dries Deeren,Larisa Girshova,Jürgen Krauter,Giovanni Martinelli,Pau Montesinos,Jonas A. Schäfer,Oliver Ottmann,Mario Petrini,Arnaud Pigneux,Alessandro Rambaldi,Christian Recher,Rebeca Rodriguez-Veiga,David Taussig,Norbert Vey,Sung-Soo Yoon,Marion Ott,Susanne Muehlbauer,Benjamin M. Beckermann,Olivier Catalani,Magali Genevray,Kirsten Mundt,Candice Jamois,Pierre Fenaux,Andrew H. Wei
View Articletitled, Idasanutlin plus cytarabine in relapsed or refractory acute myeloid leukemia: results of the MIRROS trial
Supplemental data
Depletion of CLL cells by venetoclax treatment reverses oxidative stress and impaired glycolysis in CD4 T cells
Clinical Trials & Observations
J. A. C. van Bruggen,G. J. W. van der Windt,M. Hoogendoorn,J. Dubois,Arnon P. Kater,F. S. Peters
View Articletitled, Depletion of CLL cells by venetoclax treatment reverses oxidative stress and impaired glycolysis in CD4 T cells
Supplemental data
Relative hypercoagulation induced by suppressed fibrinolysis after tisagenlecleucel infusion in malignant lymphoma
Clinical Trials & Observations
Makiko Yamasaki-Morita,Yasuyuki Arai,Takashi Ishihara,Tomoko Onishi,Hanako Shimo,Kayoko Nakanishi,Yukiko Nishiyama,Tomoyasu Jo,Hidefumi Hiramatsu,Takaya Mitsuyoshi,Chisaki Mizumoto,Junya Kanda,Momoko Nishikori,Toshio Kitawaki,Keiji Nogami,Akifumi Takaori-Kondo,Miki Nagao,Souichi Adachi
View Articletitled, Relative hypercoagulation induced by suppressed fibrinolysis after tisagenlecleucel infusion in malignant lymphoma
Supplemental data
A real-world study of combined modality therapy for early-stage Hodgkin lymphoma: too little treatment impacts outcome
Clinical Trials & Observations
Karan L. Chohan,Jason R. Young,Scott Lester,Muhamad Alhaj Moustafa,Allison Rosenthal,Han W. Tun,Bradford S. Hoppe,Patrick B. Johnston,Ivana N. Micallef,Thomas M. Habermann,Stephen M. Ansell
View Articletitled, A real-world study of combined modality therapy for early-stage Hodgkin lymphoma: too little treatment impacts outcome
Supplemental data
Development and performance of a hereditary hemorrhagic telangiectasia-specific quality-of-life instrument
Clinical Trials & Observations
Raj S. Kasthuri,Shruti Chaturvedi,Sonia Thomas,Nathan Vandergrift,Carla Bann,Nicole Schaefer,Marianne S. Clancy,Reed Pyeritz,Keith R. McCrae
View Articletitled, Development and performance of a hereditary hemorrhagic telangiectasia-specific quality-of-life instrument
Supplemental data

HEALTH SERVICES AND OUTCOMES

Code status transitions in patients with high-risk acute myeloid leukemia
Hannah R. Abrams,Ryan D. Nipp,Lara Traeger,Mitchell W. Lavoie,Matthew J. Reynolds,Nneka N. Ufere,Annie C. Wang,Kofi Boateng,Thomas W. LeBlanc,Areej El-Jawahri
View Articletitled, Code status transitions in patients with high-risk acute myeloid leukemia

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Unmasking the suppressed immunopeptidome of EZH2-mutated diffuse large B-cell lymphomas through combination drug treatment
Christopher M. Bourne,Sung Soo Mun,Tao Dao,Zita E. H. Aretz,Zaki Molvi,Ron S. Gejman,Andrew Daman,Katsuyoshi Takata,Christian Steidl,Martin G. Klatt,David A. Scheinberg
View Articletitled, Unmasking the suppressed immunopeptidome of EZH2-mutated diffuse large B-cell lymphomas through combination drug treatment
Supplemental data

LYMPHOID NEOPLASIA

Evaluating real-world treatment patterns and outcomes of mantle cell lymphoma
Mayur Narkhede,Gaurav Goyal,Lauren Shea,Amit Mehta,Smith Giri
View Articletitled, Evaluating real-world treatment patterns and outcomes of mantle cell lymphoma
Latent membrane proteins from EBV differentially target cellular pathways to accelerate MYC-induced lymphomagenesis
Masato Ikeda,Cooper K. Hayes,Samantha J. Schaller,Richard Longnecker
View Articletitled, Latent membrane proteins from EBV differentially target cellular pathways to accelerate MYC-induced lymphomagenesis
Supplemental data

MYELOID NEOPLASIA

Monocytosis and its association with clonal hematopoiesis in community-dwelling individuals
Isabelle A. van Zeventer,Aniek O. de Graaf,Theresia N. Koorenhof-Scheele,Bert A. van der Reijden,Melanie M. van der Klauw,Avinash G. Dinmohamed,Arjan Diepstra,Jan Jacob Schuringa,Luca Malcovati,Gerwin Huls,Joop H. Jansen
View Articletitled, Monocytosis and its association with clonal hematopoiesis in community-dwelling individuals
Supplemental data

PLATELETS AND THROMBOPOIESIS

Genome-wide association study of platelet factor 4/heparin antibodies in heparin-induced thrombocytopenia
Jason B. Giles,Heidi E. Steiner,Jerome Rollin,Christian M. Shaffer,Yukihide Momozawa,Taisei Mushiroda,Chihiro Inai,Kathleen Selleng,Thomas Thiele,Claire Pouplard,Nancy M. Heddle,Michiaki Kubo,Elise C. Miller,Kiana L. Martinez,Elizabeth J. Phillips,Theodore E. Warkentin,Yves Gruel,Andreas Greinacher,Dan M. Roden,Jason H. Karnes
View Articletitled, Genome-wide association study of platelet factor 4/heparin antibodies in heparin-induced thrombocytopenia
Supplemental data
GPVI expression is linked to platelet size, age, and reactivity
Alicia Veninga,Stefan Handtke,Konstanze Aurich,Bibian M. E. Tullemans,Sanne L. N. Brouns,Silas L. Schwarz,Floor C. J. I. Heubel-Moenen,Andreas Greinacher,Johan W. M. Heemskerk,Paola E. J. van der Meijden,Thomas Thiele
View Articletitled, GPVI expression is linked to platelet size, age, and reactivity
Supplemental data

THROMBOSIS AND HEMOSTASIS

The clinical and laboratory diagnosis of vaccine-induced immune thrombotic thrombocytopenia
Anna-Lise Bissola,Mercy Daka,Donald M. Arnold,James W. Smith,Jane C. Moore,Rumi Clare,Nikola Ivetic,John G. Kelton,Ishac Nazy
View Articletitled, The clinical and laboratory diagnosis of vaccine-induced immune thrombotic thrombocytopenia
The bleeding phenotype in people with nonsevere hemophilia
Fabienne R. Kloosterman,Anne-Fleur Zwagemaker,Catherine N. Bagot,Erik A. M. Beckers,Giancarlo Castaman,Marjon H. Cnossen,Peter W. Collins,Charles Hay,Michel Hof,Britta Laros-van Gorkom,Frank W. G. Leebeek,Christoph Male,Karina Meijer,Ingrid Pabinger,Susan Shapiro,Michiel Coppens,Karin Fijnvandraat,Samantha C. Gouw,,on behalf of the DYNAMO study group
View Articletitled, The bleeding phenotype in people with nonsevere hemophilia
Supplemental data
Influence of N-glycosylation in the A and C domains on the immunogenicity of factor VIII
Amber Vander Kooi,Shuaishuai Wang,Meng-Ni Fan,Alex Chen,Junping Zhang,Chun-Yu Chen,Xiaohe Cai,Barbara A. Konkle,Weidong Xiao,Lei Li,Carol H. Miao
View Articletitled, Influence of N-glycosylation in the A and C domains on the immunogenicity of factor VIII
Supplemental data
Developing and validating a mortality prediction model for ICH in ITP: a nationwide representative multicenter study
Shan Chong,Peng Zhao,Rui-Bin Huang,Hu Zhou,Jia-Ning Zhang,Ming Hou,Yi Liu,Hong-Xia Yao,Ting Niu,Jun Peng,Ming Jiang,Yan-Qiu Han,Jian-Da Hu,Ze-Ping Zhou,Lin Qiu,Lian-Sheng Zhang,Xin Wang,Hua-Quan Wang,Ru Feng,Lin-Hua Yang,Liang-Ming Ma,Shun-Qing Wang,Pei-Yan Kong,Wen-Sheng Wang,Hui-Ping Sun,Jing Sun,He-Bing Zhou,Tie-Nan Zhu,Li-Ru Wang,Jing-Yu Zhang,Qiu-Sha Huang,Hai-Xia Fu,Ye-Jun Wu,Yue-Ying Li,Qian-Fei Wang,Qian Jiang,Hao Jiang,Jin Lu,Xiao-Jun Huang,Xiao-Hui Zhang
View Articletitled, Developing and validating a mortality prediction model for ICH in ITP: a nationwide representative multicenter study
Supplemental data

TRANSPLANTATION

The ISHLT chronic lung allograft dysfunction consensus criteria are applicable to pulmonary chronic graft-versus-host disease
Yifan Pang,Ananth V. Charya,Michael B. Keller,Arlene Sirajuddin,Yi-Ping Fu,Noa G. Holtzman,Steven Z. Pavletic,Sean Agbor-Enoh
View Articletitled, The ISHLT chronic lung allograft dysfunction consensus criteria are applicable to pulmonary chronic graft-versus-host disease
Supplemental data
HLA-matching with PTCy: a reanalysis of a CIBMTR dataset with propensity score matching and donor age
Clinical Trials & Observations
Alexander Ambinder,Tania Jain,Hua-Ling Tsai,Mary M. Horowitz,Richard J. Jones,Ravi Varadhan
View Articletitled, HLA-matching with PTCy: a reanalysis of a CIBMTR dataset with propensity score matching and donor age
Supplemental data
Long-term patient-reported neurocognitive outcomes in adult survivors of hematopoietic cell transplant
Natalie L. Wu,Amanda I. Phipps,Kevin R. Krull,Karen L. Syrjala,Paul A. Carpenter,Laura S. Connelly-Smith,Mary E. Flowers,Elizabeth F. Krakow,Masumi Ueda Oshima,Stephanie J. Lee,Eric J. Chow
View Articletitled, Long-term patient-reported neurocognitive outcomes in adult survivors of hematopoietic cell transplant
Supplemental data

VASCULAR BIOLOGY

Cerebral vascular injury in transplant-associated thrombotic microangiopathy
Anthony Sabulski,Grace Arcuri,Sara Szabo,Marguerite M. Care,Christopher E. Dandoy,Stella M. Davies,Sonata Jodele
View Articletitled, Cerebral vascular injury in transplant-associated thrombotic microangiopathy

RESEARCH LETTERS

ALLSorts: an RNA-Seq subtype classifier for B-cell acute lymphoblastic leukemia
Breon Schmidt,Lauren M. Brown,Georgina L. Ryland,Andrew Lonsdale,Hansen J. Kosasih,Louise E. Ludlow,Ian J. Majewski,Piers Blombery,Paul G. Ekert,Nadia M. Davidson,Alicia Oshlack
View Articletitled, ALLSorts: an RNA-Seq subtype classifier for B-cell acute lymphoblastic leukemia
Supplemental data
Epigenome-wide association study of acute lymphoblastic leukemia in children with Down syndrome
Shaobo Li,Pagna Sok,Keren Xu,Ivo S. Muskens,Natalina Elliott,Swe Swe Myint,Priyatama Pandey,Helen M. Hansen,Libby M. Morimoto,Alice Y. Kang,Catherine Metayer,Xiaomei Ma,Beth A. Mueller,Anindita Roy,Irene Roberts,Karen R. Rabin,Austin L. Brown,Philip J. Lupo,Joseph L. Wiemels,Adam J. de Smith
View Articletitled, Epigenome-wide association study of acute lymphoblastic leukemia in children with Down syndrome
Supplemental data
Inhibition of casein kinase 1δ disrupts translation initiation and exerts potent antilymphoma activity
Ipsita Pal,Andre M. Sardinha Grilo,Alec Gaspary,Sohani Das Sharma,Luigi Scotto,Owen A. O'Connor,Marko Jovanovic,Changchun Deng,Luke E. Berchowitz
View Articletitled, Inhibition of casein kinase 1δ disrupts translation initiation and exerts potent antilymphoma activity
Supplemental data
Pediatric patient with fibrinogen Villeurbanne II presenting with an unprovoked portal vein thrombosis
Brenton J. Francisco,Bal Krishan Sharma,Hannah M. Russell,Leah Rosenfeldt,A. Phillip Owens, III,Matthew J. Flick,Eric S. Mullins,Joseph Palumbo
View Articletitled, Pediatric patient with fibrinogen Villeurbanne II presenting with an unprovoked portal vein thrombosis
An R307H substitution in GATA1 that prevents Ser310 phosphorylation causes severe fetal anemia
Benjamin Hetzer,Andreas Meryk,Gabriele Kropshofer,Caroline Bargehr,Raul Jimenez-Heredia,Kaan Boztug,Beatrix E. Mühlegger,Michael Dworzak,Thomas Gruber,Roman Crazzolara
View Articletitled, An R307H substitution in GATA1 that prevents Ser310 phosphorylation causes severe fetal anemia
Supplemental data
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