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Theodore W. Laetsch
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Journal Articles

HLH-like toxicities predict poor survival after the use of tisagenlecleucel in children and young adults with B-ALL

Clinical Trials & Observations
Kevin O. McNerney, Stephanie J. Si Lim, Kyle Ishikawa, Alexandra Dreyzin, Anant Vatsayan, John J. Chen, Christina Baggott, Snehit Prabhu, Holly L. Pacenta, Christine Philips, Jenna Rossoff, Heather E. Stefanski, Julie-An Talano, Amy Moskop, Michael Verneris, Doug Myers, Nicole A. Karras, Patrick Brown, Challice L. Bonifant, Muna Qayed, Michelle Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Susanne H. C. Baumeister, Vanessa A. Fabrizio, Vasant Chinnabhandar, Emily Egeler, Sharon Mavroukakis, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Liora M. Schultz
Journal: Blood Advances
Blood Adv (2023) 7 (12): 2758–2771.
https://doi.org/10.1182/bloodadvances.2022008893
Published: 2023
Includes: Supplemental data
Journal Articles

Preinfusion factors impacting relapse immunophenotype following CD19 CAR T cells

Adam J. Lamble, Regina M. Myers, Agne Taraseviciute, Samuel John, Bonnie Yates, Seth M. Steinberg, Jennifer Sheppard, Alexandra E. Kovach, Brent Wood, Michael J. Borowitz, Maryalice Stetler-Stevenson, Constance M. Yuan, Vinodh Pillai, Toni Foley, Perry Chung, Lee Chen, Daniel W. Lee, Colleen Annesley, Amanda DiNofia, Stephan A. Grupp, Michael R. Verneris, Lia Gore, Theodore W. Laetsch, Deepa Bhojwani, Patrick A. Brown, Michael A. Pulsipher, Susan R. Rheingold, Rebecca A. Gardner, Nirali N. Shah
Journal: Blood Advances
Blood Adv (2023) 7 (4): 575–585.
https://doi.org/10.1182/bloodadvances.2022007423
Published: 2023
Includes: Supplemental data
Journal Articles

Higher doses of tisagenlecleucel are associated with improved outcomes: a report from the pediatric real-world CAR consortium

Heather E. Stefanski, Anne Eaton, Christina Baggott, Jenna Rossoff, Michael R. Verneris, Snehit Prabhu, Holly L. Pacenta, Christine L. Phillips, Julie-An Talano, Amy Moskop, Steven P. Margossian, Gary Douglas Myers, Nicole A. Karras, Patrick A. Brown, Muna Qayed, Michelle Hermiston, Prakash Satwani, M. Christa Krupski, Amy K. Keating, Rachel Wilcox, Cara A. Rabik, Vanessa A. Fabrizio, Vasant Chinnabhandar, A. Yasemin Goksenin, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Liora M. Schultz
Journal: Blood Advances
Blood Adv (2023) 7 (4): 541–548.
https://doi.org/10.1182/bloodadvances.2022007246
Published: 2023
Includes: Supplemental data
Journal Articles

Low rate of subsequent malignant neoplasms after CD19 CAR T-cell therapy

Emily M. Hsieh, Regina M. Myers, Bonnie Yates, Colleen Annesley, Samuel John, Agne Taraseviciute, Seth M. Steinberg, Jennifer Sheppard, Perry Chung, Lee Chen, Daniel W. Lee, Amanda DiNofia, Stephan A. Grupp, Michael R. Verneris, Theodore W. Laetsch, Deepa Bhojwani, Patrick A. Brown, Michael A. Pulsipher, Susan R. Rheingold, Rebecca A. Gardner, Lia Gore, Nirali N. Shah, Adam J. Lamble
Journal: Blood Advances
Blood Adv (2022) 6 (17): 5222–5226.
https://doi.org/10.1182/bloodadvances.2022008093
Published: 2022
Journal Articles

Real-world use of tisagenlecleucel in infant acute lymphoblastic leukemia

Amy Moskop, Lauren Pommert, Christina Baggott, Snehit Prabhu, Holly L. Pacenta, Christine L. Phillips, Jenna Rossoff, Heather E. Stefanski, Julie-An Talano, Steve P. Margossian, Michael R. Verneris, G. Doug Myers, Nicole A. Karras, Patrick A. Brown, Muna Qayed, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Rachel Wilcox, Cara A. Rabik, Vanessa A. Fabrizio, Vasant Chinnabhandar, A. Yasemin Goksenin, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Erin M. Guest, Erin H. Breese, Liora M. Schultz
Journal: Blood Advances
Blood Adv (2022) 6 (14): 4251–4255.
https://doi.org/10.1182/bloodadvances.2021006393
Published: 2022
Journal Articles

Optimal fludarabine lymphodepletion is associated with improved outcomes after CAR T-cell therapy

Clinical Trials & Observations
Vanessa A. Fabrizio, Jaap Jan Boelens, Audrey Mauguen, Christina Baggott, Snehit Prabhu, Emily Egeler, Sharon Mavroukakis, Holly Pacenta, Christine L. Phillips, Jenna Rossoff, Heather E. Stefanski, Julie-An Talano, Amy Moskop, Steven P. Margossian, Michael R. Verneris, Gary Douglas Myers, Nicole A. Karras, Patrick A. Brown, Muna Qayed, Michelle Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Rachel Wilcox, Cara A. Rabik, Vasant Chinnabhandar, Michael Kunicki, A. Yasemin Goksenin, Crystal L. Mackall, Theodore W. Laetsch, Liora M. Schultz, Kevin J. Curran
Journal: Blood Advances
Blood Adv (2022) 6 (7): 1961–1968.
https://doi.org/10.1182/bloodadvances.2021006418
Published: 2022
Includes: Supplemental data
Journal Articles

Tisagenlecleucel outcomes in relapsed/refractory extramedullary ALL: a Pediatric Real World CAR Consortium Report

Clinical Trials & Observations
Vanessa A. Fabrizio, Christine L. Phillips, Adam Lane, Christina Baggott, Snehit Prabhu, Emily Egeler, Sharon Mavroukakis, Holly Pacenta, Jenna Rossoff, Heather E. Stefanski, Julie-An Talano, Amy Moskop, Steven P. Margossian, Michael R. Verneris, Gary Douglas Myers, Nicole A. Karras, Patrick A. Brown, Muna Qayed, Michelle Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Rachel Wilcox, Cara A. Rabik, Vasant Chinnabhandar, Michael Kunicki, A. Yasemin Goksenin, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Liora M. Schultz
Journal: Blood Advances
Blood Adv (2022) 6 (2): 600–610.
https://doi.org/10.1182/bloodadvances.2021005564
Published: 2022
Journal Articles

Tisagenlecleucel immunogenicity in relapsed/refractory acute lymphoblastic leukemia and diffuse large B-cell lymphoma

Clinical Trials & Observations
Karen Thudium Mueller, Stephan A. Grupp, Shannon L. Maude, John E. Levine, Michael A. Pulsipher, Michael W. Boyer, Keith J. August, G. Doug Myers, Constantine S. Tam, Ulrich Jaeger, Stephen Ronan Foley, Peter Borchmann, Stephen J. Schuster, Edmund K. Waller, Rakesh Awasthi, Bernd Potthoff, Andy Warren, Edward R. Waldron, Fraser McBlane, Andrea Chassot-Agostinho, Theodore W. Laetsch
Journal: Blood Advances
Blood Adv (2021) 5 (23): 4980–4991.
https://doi.org/10.1182/bloodadvances.2020003844
Published: 2021
Includes: Supplemental data
Journal Articles

Practical guidelines for monitoring and management of coagulopathy following tisagenlecleucel CAR T-cell therapy

Jochen Buechner, Stephan A. Grupp, Hidefumi Hiramatsu, David T. Teachey, Susana Rives, Theodore W. Laetsch, Gregory A. Yanik, Patricia Wood, Rakesh Awasthi, Lan Yi, Andrea Chassot-Agostinho, Lamis K. Eldjerou, Barbara De Moerloose
Journal: Blood Advances
Blood Adv (2021) 5 (2): 593–601.
https://doi.org/10.1182/bloodadvances.2020002757
Published: 2021
Includes: Supplemental data