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Journal Articles

Babesiosis and sickle red blood cells: loss of deformability, altered osmotic fragility, and hypervesiculation

Divya Beri, Marilis Rodriguez, Manpreet Singh, Daniel McLaughlin, Yunfeng Liu, Hui Zhong, Avital Mendelson, Xiuli An, Deepa Manwani, Karina Yazdanbakhsh, Cheryl A. Lobo

Blood (2025) 145 (19): 2202–2213.

https://doi.org/10.1182/blood.2024027602

Published: 2025

Includes: Supplemental data

Journal Articles

Novel, potent, and orally bioavailable LSD1 inhibitors induce fetal hemoglobin synthesis in a sickle cell disease mouse model

Yu Wang, Lei Yu, Kaiwen Deng, Mathivanan Packiarajan, Angelo Aguilar, Sojin An, Greggory Myers, Hoon Oh, Sharon A. Singh, Uhn-soo Cho, Shaomeng Wang, Yuanfang Guan, Andrew White, Rami Khoriaty, James Douglas Engel

Blood blood.2024028006.

https://doi.org/10.1182/blood.2024028006

Published: 2025

Includes: Supplemental data

Journal Articles

A Novel Mouse Model of Hemoglobin SC Disease Reveals Mechanisms Underlying Beneficial Effects of Hydroxyurea

Tahereh Setayesh, Mengna Chi, Zachery Oestreicher, Masahide Sakabe, Katie Giger Seu, Zhenqi Zhu, Harsimran Kaur, Anifat Tijani, Mei Xin, Amy Shova, Kenneth D Greis, Tim M. Townes, Jozsef Balla, Katherine VandenHeuvel, Yueh-Chiang Hu, Punam Malik

Blood blood.2024028136.

https://doi.org/10.1182/blood.2024028136

Published: 2025

Includes: Supplemental data

Journal Articles

17( R )-Resolvin D1 protects against sickle cell–related inflammatory cardiomyopathy in humanized mice

Enrica Federti, Domenico Mattoscio, Antonio Recchiuti, Alessandro Matte, Maria Monti, Flora Cozzolino, Manuela Iezzi, Martina Ceci, Alessandra Ghigo, Emanuela Tolosano, Angela Siciliano, Jacopo Ceolan, Veronica Riccardi, Elisa Gremese, Carlo Brugnara, Lucia De Franceschi

Blood (2025) 145 (17): 1915–1928.

https://doi.org/10.1182/blood.2024024768

Published: 2025

Includes: Supplemental data

Journal Articles

How I treat anemia in myelofibrosis

Akriti G. Jain, Aaron T. Gerds

Blood (2025) 145 (16): 1738–1746.

https://doi.org/10.1182/blood.2023022414

Published: 2025

Journal Articles

The evolving landscape of hereditary stomatocytosis

Immacolata Andolfo, Achille Iolascon, Roberta Russo

Blood blood.2024024294.

https://doi.org/10.1182/blood.2024024294

Published: 2025

Journal Articles

Maternal Tmprss6 is required for hepcidin suppression and fetal health

Katherine Louise Fielding, Cavan Bennett, Anne Pettikiriarachchi, Naomi Jones, Rebecca Harding, Alistair R.D. McLean, Louise M Randall, Ute Schaeper, Alberto Martinez, PhD, Ricardo Ataide, Sant-Rayn Pasricha

Blood blood.2024027563.

https://doi.org/10.1182/blood.2024027563

Published: 2025

Includes: Supplemental data

Journal Articles

Breakthrough hemolysis in paroxysmal nocturnal hemoglobinuria throughout clinical trials: from definition to clinical practice

Bruno Fattizzo, Francesco Versino, Wilma Barcellini

Blood blood.2024027574.

https://doi.org/10.1182/blood.2024027574

Published: 2025

Includes: Supplemental data

Journal Articles

Paraspinal mass and lower extremity weakness in a patient with thalassemia

Chad Zik, William B. Ershler

Blood (2025) 145 (15): 1702.

https://doi.org/10.1182/blood.2024028049

Published: 2025

Journal Articles

How I manage patients with unexplained cytopenia

Luca Malcovati, Mario Cazzola

Blood (2025) 145 (15): 1610–1620.

https://doi.org/10.1182/blood.2024025771

Published: 2025

Journal Articles

X-linked sideroblastic anemia in females

Sarah Ducamp, Dean R. Campagna, Anoop K. Sendamarai, Paul J. Schmidt, Harrison K. Tsai, Matthew M. Heeney, Sylvia S. Bottomley, Mark D. Fleming

Blood (2025) 145 (14): 1583–1587.

https://doi.org/10.1182/blood.2024024475

Published: 2025

Includes: Supplemental data

Journal Articles

Iron overload in HFE-related hemochromatosis severely impairs Vδ2 γδ T-cell homeostasis

Derya Erdogdu, Ina Becoku, Valerie Huber, Yao Wang, Matthias Eyrich, Hisayoshi Hashimoto, Michaela Döring, Johannes H. Schulte, Karin Schilbach

Blood blood.2024025345.

https://doi.org/10.1182/blood.2024025345

Published: 2025

Includes: Supplemental data

Journal Articles

Sickle cell trait does not cause “sickle cell crisis” leading to exertion-related death: a systematic review

Lachelle D. Weeks, Allecia M. Wilson, Rakhi P. Naik, Yvonne Efebera, M. Hassan Murad, Anjlee Mahajan, Patrick T. McGann, Madeleine Verhovsek, Angela C. Weyand, Ahmar U. Zaidi, Michael R. DeBaun, Chancellor Donald, Roger A. Mitchell

Blood (2025) 145 (13): 1345–1352.

https://doi.org/10.1182/blood.2024026899

Published: 2025

Includes: Supplemental data

Journal Articles

Diabetes Mellitus and APOL1 Genotype Increase the Risk for Chronic Kidney Disease Progression in Sickle Cell Disease

Ryan Sun, Anand Srivastava, Joseph L Zapater, Franklin Njoku, Jin Han, Zalaya K Ivy, Marwah W. Farooqui, Insia Rizvi, Brian T Layden, Robert Molokie, Victor R Gordeuk, Santosh L Saraf

Blood blood.2024027839.

https://doi.org/10.1182/blood.2024027839

Published: 2025

Includes: Supplemental data

Journal Articles

Mutations in AMBRA1 aggravate β-thalassemia by impairing autophagy-mediated clearance of free α-globin

Blood (2025) 145 (10): 1074–1088.

https://doi.org/10.1182/blood.2023022688

Published: 2025

Includes: Supplemental data

Journal Articles

Inflammation-driven NF-κB signaling represses ferroportin transcription in macrophages via HDAC1 and HDAC3

Oriana Marques, Natalie K. Horvat, Laura Zechner, Silvia Colucci, Richard Sparla, Stefan Zimmermann, Christopher J. Neufeldt, Sandro Altamura, Ruiyue Qiu, Katja Müdder, Günter Weiss, Matthias W. Hentze, Martina U. Muckenthaler

Blood (2025) 145 (8): 866–880.

https://doi.org/10.1182/blood.2023023417

Published: 2025

Includes: Supplemental data

Journal Articles

Long-term efficacy and safety of danicopan as add-on therapy to ravulizumab or eculizumab in PNH with significant EVH

Austin Kulasekararaj, Morag Griffin, Caroline Piatek, Jamile Shammo, Jun-ichi Nishimura, Christopher Patriquin, Hubert Schrezenmeier, Wilma Barcellini, Jens Panse, Anna Gaya, Yogesh Patel, Peng Liu, Gleb Filippov, Flore Sicre de Fontbrune, Antonio Risitano, Jong Wook Lee

Blood (2025) 145 (8): 811–822.

https://doi.org/10.1182/blood.2024026299

Published: 2025

Includes: Supplemental data

Journal Articles

Ferroptosis regulates hemolysis in stored murine and human red blood cells

Blood (2025) 145 (7): 765–783.

https://doi.org/10.1182/blood.2024026109

Published: 2025

Includes: Supplemental data

Journal Articles

β-Thalassemia minor is associated with high rates of worsening anemia in pregnancy

Arielle L. Langer, Brynn B. Goggins, Erica B. Esrick, Geoffrey Fell, Nancy Berliner, Katherine E. Economy

Blood (2025) 145 (6): 648–651.

https://doi.org/10.1182/blood.2024026736

Published: 2025

Includes: Supplemental data

Journal Articles

The hepcidin-ferroportin axis modulates liver endothelial cell BMP expression to influence iron homeostasis in mice

Allison L. Fisher, Sydney Phillips, Chia-Yu Wang, Joao A. Paulo, Xia Xiao, Yang Xu, Gillian A. Moschetta, Yongqiang Xue, Joseph D. Mancias, Jodie L. Babitt

Blood (2025) 145 (6): 625–634.

https://doi.org/10.1182/blood.2024024795

Published: 2025

Includes: Supplemental data

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Babesiosis and sickle red blood cells: loss of deformability, altered osmotic fragility, and hypervesiculation

Novel, potent, and orally bioavailable LSD1 inhibitors induce fetal hemoglobin synthesis in a sickle cell disease mouse model

A Novel Mouse Model of Hemoglobin SC Disease Reveals Mechanisms Underlying Beneficial Effects of Hydroxyurea

17( R )-Resolvin D1 protects against sickle cell–related inflammatory cardiomyopathy in humanized mice

How I treat anemia in myelofibrosis

The evolving landscape of hereditary stomatocytosis

Maternal Tmprss6 is required for hepcidin suppression and fetal health

Breakthrough hemolysis in paroxysmal nocturnal hemoglobinuria throughout clinical trials: from definition to clinical practice

Paraspinal mass and lower extremity weakness in a patient with thalassemia

How I manage patients with unexplained cytopenia

X-linked sideroblastic anemia in females

Iron overload in HFE-related hemochromatosis severely impairs Vδ2 γδ T-cell homeostasis

Sickle cell trait does not cause “sickle cell crisis” leading to exertion-related death: a systematic review

Diabetes Mellitus and APOL1 Genotype Increase the Risk for Chronic Kidney Disease Progression in Sickle Cell Disease

Mutations in AMBRA1 aggravate β-thalassemia by impairing autophagy-mediated clearance of free α-globin

Inflammation-driven NF-κB signaling represses ferroportin transcription in macrophages via HDAC1 and HDAC3

Long-term efficacy and safety of danicopan as add-on therapy to ravulizumab or eculizumab in PNH with significant EVH

Ferroptosis regulates hemolysis in stored murine and human red blood cells

β-Thalassemia minor is associated with high rates of worsening anemia in pregnancy

The hepcidin-ferroportin axis modulates liver endothelial cell BMP expression to influence iron homeostasis in mice

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