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Journal Articles

Array genotyping of transfusion-relevant blood cell antigens in 6946 ancestrally diverse study participants

Blood (2025) 146 (12): 1511–1524.

https://doi.org/10.1182/blood.2025028902

Published: 2025

Includes: Supplemental data

Journal Articles

Rbm38 Deficiency Impairs Erythroid Heme Biosynthesis and Induces Porphyria via Reduced Ferrochelatase Expression

Blood blood.2025028783.

https://doi.org/10.1182/blood.2025028783

Published: 2025

Includes: Supplemental data

Journal Articles

Intestinal hepcidin overexpression promotes iron deficiency anemia and counteracts iron overload via DMT1 downregulation

Marion Falabrègue, Candice Aurrand, Léa Cazaulon, Nadia Boussetta, Sara Zumerle, Zoubida Karim, Nouzha Djebrani-Oussedik, Joel POUPON, Sandra Guilmeau, Emeric Dupe, Anne Aucouturier, Philippe Langella, Luis G Bermudez-Humaran, Sophie Vaulont, Carole Peyssonnaux

Blood blood.2025028370.

https://doi.org/10.1182/blood.2025028370

Published: 2025

Includes: Supplemental data

Journal Articles

TNFα signaling restores steady-state hematopoiesis in a TNFαKO mouse model of anemia of inflammation

Amaliris Guerra, Vania Lo Presti, Ding-Wen Chen, Ana Catarina Martins, Ariel Rivera, Nolan Hamilton, Pankja Sharma, Yelena Z. Ginzburg, Carlo Castruccio Castracani, Carla Casu, Ritama Gupta, Raffaella Gozzelino, Edward M. Behrens, Laura F. Bennett, Robert F. Paulson, Peter Kurre, Stefano Rivella

Blood (2025) 146 (8): 984–997.

https://doi.org/10.1182/blood.2025029352

Published: 2025

Includes: Supplemental data

Journal Articles

Gene Therapy for HbSC Disease and other Compound Heterozygous Sickle Hemoglobinopathies: A Time for Inclusion

Andrew Wilks, Martin H Steinberg, Haydar Frangoul

Blood blood.2025029964.

https://doi.org/10.1182/blood.2025029964

Published: 2025

Journal Articles

Reactivation of developmentally silenced globin genes through forced linear recruitment of remote enhancers

Anna-Karina Felder, Sjoerd J. D. Tjalsma, Han J. M. P. Verhagen, Rezin Majied, Marjon J. A. M. Verstegen, Thijs C. J. Verheul, Jeffrey van Haren, Rebecca Mohnani, Richard Gremmen, Peter H. L. Krijger, Sjaak Philipsen, Emile van den Akker, Wouter de Laat

Blood (2025) 146 (6): 732–744.

https://doi.org/10.1182/blood.2024028128

Published: 2025

Includes: Supplemental data

Journal Articles

Breakthrough hemolysis in paroxysmal nocturnal hemoglobinuria throughout clinical trials: from definition to clinical practice

Bruno Fattizzo, Francesco Versino, Wilma Barcellini

Blood (2025) 146 (4): 411–421.

https://doi.org/10.1182/blood.2024027574

Published: 2025

Includes: Supplemental data

Journal Articles

Novel, potent, and orally bioavailable LSD1 inhibitors induce fetal hemoglobin synthesis in a sickle cell disease mouse model

Yu Wang, Lei Yu, Kaiwen Deng, Mathivanan Packiarajan, Angelo Aguilar, Sojin An, Xiaofang Liu, Greggory Myers, Hoon Oh, Sharon A. Singh, Uhn-soo Cho, Shaomeng Wang, Yuanfang Guan, Andrew D. White, Rami Khoriaty, James Douglas Engel

Blood (2025) 146 (3): 356–368.

https://doi.org/10.1182/blood.2024028006

Published: 2025

Includes: Supplemental data

Journal Articles

Unveiling the truth: different names, same antigen

Nelson H. Tsuno, Daisuke Takahashi

Blood (2025) 146 (2): 141–143.

https://doi.org/10.1182/blood.2025028939

Published: 2025

Journal Articles

Iron overload impacts TCR γδ cell immunity

José Pedro Loureiro, M. Fátima Macedo

Blood (2025) 146 (2): 139–140.

https://doi.org/10.1182/blood.2025029261

Published: 2025

Journal Articles

The neutrophil antigen 3a/b polymorphism in SLC44A2 unexpectedly encodes the Cs a /Cs b red cell antigens

Blood (2025) 146 (2): 247–253.

https://doi.org/10.1182/blood.2024026285

Published: 2025

Includes: Supplemental data

Journal Articles

Iron overload in HFE-related hemochromatosis severely impairs Vδ2 + γδ T-cell homeostasis

Derya Erdogdu, Ina Becoku, Valerie Huber, Yao Wang, Matthias Eyrich, Hisayoshi Hashimoto, Michaela Döring, Johannes Schulte, Karin Schilbach

Blood (2025) 146 (2): 219–232.

https://doi.org/10.1182/blood.2024025345

Published: 2025

Includes: Supplemental data

Journal Articles

A novel mouse model of hemoglobin SC disease reveals mechanisms underlying beneficial effects of hydroxyurea

Tahereh Setayesh, Mengna Chi, Zachery Oestreicher, Masahide Sakabe, Katie Seu, Zhenqi Zhu, Harsimran Kaur, Anifat Tijani, Mei Xin, Amy Shova, Kenneth D. Greis, Tim M. Townes, József Balla, Katherine VandenHeuvel, Yueh-Chiang Hu, Punam Malik

Blood (2025) 146 (1): 13–28.

https://doi.org/10.1182/blood.2024028136

Published: 2025

Includes: Supplemental data

Journal Articles

A controlled trial for preventing priapism in sickle cell anemia: hydroxyurea plus placebo vs hydroxyurea plus tadalafil

Ibrahim M. Idris, Aminu A. Yusuf, Ismail I. Ismail, Awwal M. Borodo, Mustapha S. Hikima, Shehu A. Kana, Tukur Aliyu, Kabiru Musangedu, Atiku Umar Jibrilla, Sani A. Aji, Aisha Kuliya-Gwarzo, Kabir Mohammad, Jamil A. Galadanci, Rukayya Alkassim, Mohammad A. Suwaid, Nafiu Hussaini, Mark Rodeghier, Arthur L. Burnett, Michael R. DeBaun

Blood (2025) 145 (26): 3101–3112.

https://doi.org/10.1182/blood.2024027898

Published: 2025

Includes: Supplemental data

Journal Articles

The evolving landscape of hereditary stomatocytosis

Immacolata Andolfo, Achille Iolascon, Roberta Russo

Blood (2025) 145 (26): 3089–3100.

https://doi.org/10.1182/blood.2024024294

Published: 2025

Journal Articles

The endothelial mTORC2-Foxo1 axis serves as an iron-responsive sensor governing systemic iron homeostasis

Blood blood.2025028454.

https://doi.org/10.1182/blood.2025028454

Published: 2025

Includes: Supplemental data

Journal Articles

Maternal Tmprss6 is required for hepcidin suppression and fetal health

Katherine L. Fielding, Cavan Bennett, Anne Pettikiriarachchi, Naomi Jones, Rebecca Harding, Alistair R. D. McLean, Louise Randall, Ute Schaeper, Alberto Martinez, Ricardo Ataíde, Sant-Rayn Pasricha

Blood (2025) 145 (25): 3056–3059.

https://doi.org/10.1182/blood.2024027563

Published: 2025

Includes: Supplemental data

Journal Articles

Severe oxidant hemolysis in a child with G6PD deficiency and Hb C trait

Connor Cocke, Weijie Li

Blood (2025) 145 (25): 3060.

https://doi.org/10.1182/blood.2025029037

Published: 2025

Journal Articles

Diabetes mellitus and APOL1 genotype increase the risk for chronic kidney disease progression in sickle cell disease

Ryan Sun, Anand Srivastava, Joseph L. Zapater, Franklin Njoku, Jin Han, Zalaya Ivy, Marwah Farooqui, Insia Rizvi, Brian Layden, Robert E. Molokie, Victor R. Gordeuk, Santosh L. Saraf

Blood (2025) 145 (24): 2927–2930.

https://doi.org/10.1182/blood.2024027839

Published: 2025

Includes: Supplemental data

Journal Articles

Impact of HLA alloimmunization in gene-modified autologous stem cell transplant for transfusion-dependent thalassemia

Nora M. Gibson, Eugene Khandros, Caitlin W. Elgarten, Elizabeth Worster, Dimitrios S. Monos, Alexis A. Thompson, Janet L. Kwiatkowski, Timothy S. Olson

Blood (2025) 145 (22): 2666–2670.

https://doi.org/10.1182/blood.2024027034

Published: 2025

Includes: Supplemental data

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Array genotyping of transfusion-relevant blood cell antigens in 6946 ancestrally diverse study participants

Rbm38 Deficiency Impairs Erythroid Heme Biosynthesis and Induces Porphyria via Reduced Ferrochelatase Expression

Intestinal hepcidin overexpression promotes iron deficiency anemia and counteracts iron overload via DMT1 downregulation

TNFα signaling restores steady-state hematopoiesis in a TNFαKO mouse model of anemia of inflammation

Gene Therapy for HbSC Disease and other Compound Heterozygous Sickle Hemoglobinopathies: A Time for Inclusion

Reactivation of developmentally silenced globin genes through forced linear recruitment of remote enhancers

Breakthrough hemolysis in paroxysmal nocturnal hemoglobinuria throughout clinical trials: from definition to clinical practice

Novel, potent, and orally bioavailable LSD1 inhibitors induce fetal hemoglobin synthesis in a sickle cell disease mouse model

Unveiling the truth: different names, same antigen

Iron overload impacts TCR γδ cell immunity

The neutrophil antigen 3a/b polymorphism in SLC44A2 unexpectedly encodes the Cs a /Cs b red cell antigens

Iron overload in HFE-related hemochromatosis severely impairs Vδ2 + γδ T-cell homeostasis

A novel mouse model of hemoglobin SC disease reveals mechanisms underlying beneficial effects of hydroxyurea

A controlled trial for preventing priapism in sickle cell anemia: hydroxyurea plus placebo vs hydroxyurea plus tadalafil

The evolving landscape of hereditary stomatocytosis

The endothelial mTORC2-Foxo1 axis serves as an iron-responsive sensor governing systemic iron homeostasis

Maternal Tmprss6 is required for hepcidin suppression and fetal health

Severe oxidant hemolysis in a child with G6PD deficiency and Hb C trait

Diabetes mellitus and APOL1 genotype increase the risk for chronic kidney disease progression in sickle cell disease

Impact of HLA alloimmunization in gene-modified autologous stem cell transplant for transfusion-dependent thalassemia

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American Society of Hematology

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