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Journal Articles

A Novel Mouse Model of Hemoglobin-SC Disease: Bridging the Knowledge Gap in Sickle Cell Disease

Tahereh Setayesh, Mengna Chi, Zachery Oestreicher, Masahide Sakabe, Xin Mei, Katherine Vandenheuvel, Tim M. Townes, Yueh-Chiang Hu, Punam Malik

Blood (2024) 144 (Supplement 1): 620.

https://doi.org/10.1182/blood-2024-206241

Published: 2024

Journal Articles

A novel therapeutic strategy for β-thalassemia

Tim M. Townes

Blood (2019) 133 (21): 2245–2246.

https://doi.org/10.1182/blood-2019-02-900464

Published: 2019

Journal Articles

Regulation of Hematopoietic Stem Cell Function By the Histone H2A Deubiquitinase Usp16

Yue Gu, MS, Wei Yang, PhD, Amanda Jones, PhD, Shanrun Liu, MD PhD, Qian Dai, MD PhD, C Scott Swindle, PhD, Thomas Ryan, PhD, Tim M. Townes, PhD, Christopher Klug, PhD, Hengbin Wang, PhD

Blood (2015) 126 (23): 1177.

https://doi.org/10.1182/blood.V126.23.1177.1177

Published: 2015

Journal Articles

Suppression of Antioxidant Responses in Dyskeratosis Congenita Cells

Erik Westin, PhD, Larisa Pereboeva, MD PhD, Divya Devadasan, MS, Tim M. Townes, PhD, Frederick D Goldman, MD

Blood (2015) 126 (23): 2412.

https://doi.org/10.1182/blood.V126.23.2412.2412

Published: 2015

Journal Articles

Modified IPS Cells for Hemoglobinopathies

Tim M. Townes, PhD, Lei Ding, Chia-Wei Chang, Yi-Shin Lai, Joe Sun, Kevin Pawlik

Blood (2015) 126 (23): SCI-17.

https://doi.org/10.1182/blood.V126.23.SCI-17.SCI-17

Published: 2015

Journal Articles

Crispr Modification of Induced Pluripotent Stem Derived from Diamond-Blackfan Anemia Fibroblasts

Erik Westin, PhD, Divya Devadasan, MA, Chao Li, Lei Ding, PhD, Tim M. Townes, PhD, Frederick D Goldman, MD

Blood (2014) 124 (21): 4804.

https://doi.org/10.1182/blood.V124.21.4804.4804

Published: 2014

Journal Articles

Transcription Activation of an Antisense Long Noncoding RNA (lnc-Mega1) of RBM15 By RUNX1 Enhances Megakaryocyte Differentiation

Xinyang Zhao, PhD, Ngoc-Tung Tran, PhD, Dewang Zhou, Hairui Su, Li Zhang, Tim M. Townes, PhD

Blood (2014) 124 (21): 4305.

https://doi.org/10.1182/blood.V124.21.4305.4305

Published: 2014

Journal Articles

Targeting KLF1 for the Treatment of Sickle Cell Disease Using Antisense Oligonucleotides

Raechel Peralta, MS, Audrey Low, Sheri Booten, Dewang Zhou, Aneeza Kim, Sue Freier, Shuling Guo, PhD, Sue Murray, Tim M. Townes, PhD, Gene Hung

Blood (2014) 124 (21): 4038.

https://doi.org/10.1182/blood.V124.21.4038.4038

Published: 2014

Journal Articles

Targeting BCL11A and KLF1 For The Treatment Of Sickle Cell Disease and β-Thalassemia In Vitro using Antisense Oligonucleotides

Raechel Peralta, Audrey Low, Aneeza Kim, Sue Murray, Shuling Guo, PhD, Sue Freier, Tim M. Townes, PhD, Gene Hung

Blood (2013) 122 (21): 1022.

https://doi.org/10.1182/blood.V122.21.1022.1022

Published: 2013

Journal Articles

Role Of Dpy30/MLL Complexes In Regulating Hematopoietic Progenitor Cell Maintenance and Differentiation

Zhenhua Yang, PhD, Jonathan Augustin, BA, Jing Hu, PhD, Chia-Wei Chang, PhD, Tim M. Townes, PhD, Hao Jiang, PhD

Blood (2013) 122 (21): 2424.

https://doi.org/10.1182/blood.V122.21.2424.2424

Published: 2013

Journal Articles

Heme-regulated eIF2α kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis

Rajasekhar N. V. S. Suragani, Roshini S. Zachariah, Jason G. Velazquez, Sijin Liu, Chiao-Wang Sun, Tim M. Townes, Jane-Jane Chen

Blood (2012) 119 (22): 5276–5284.

https://doi.org/10.1182/blood-2011-10-388132

Published: 2012

Includes: Supplemental data

Journal Articles

Preclinical Studies for Sickle Cell Disease Gene Therapy Using Bone Marrow CD34+ Cells Modified with a βAS3-Globin Lentiviral Vector

Fabrizia Urbinati, Ph.D, Zulema Romero Garcia, Ph.D, Sabine Geiger, Rafael Ruiz de Assin, Ph.D, Gabriela Kuftinec, Roger P. Hollis, PhD, Satiro N. De Oliveira, MD, Jennifer Wherley, Aaron Cooper, Tim M. Townes, PhD, Gay M. Crooks, MBBS, Elizabeth J Read, MD, Mark C. Walters, MD, Herbert J. Meiselman, ScD, Thomas D. Coates, MD, Victor J. Marder, M.D., Donald B. Kohn, MD

Blood (2011) 118 (21): 3119.

https://doi.org/10.1182/blood.V118.21.3119.3119

Published: 2011

Journal Articles

Genome-Wide Analysis of EKLF Occupancy in Erythroid Chromatin Reveals 5′, 3′ and Intragenic Binding Sites in EKLF Target Genes

Andre M. Pilon, MS, Elliott H. Margulies, PhD, Hatice Ozel Abaan, Amy Werner- Allen, Tim M. Townes, PhD, Abbie M. Frederick, Dewang Zhou, PhD, Patrick G. Gallagher, MD, David M. Bodine, PhD

Blood (2008) 112 (11): 283.

https://doi.org/10.1182/blood.V112.11.283.283

Published: 2008

Journal Articles

Correction of sickle cell disease by homologous recombination in embryonic stem cells

Li-Chen Wu, Chiao-Wang Sun, Thomas M. Ryan, Kevin M. Pawlik, Jinxiang Ren, Tim M. Townes

Blood (2006) 108 (4): 1183–1188.

https://doi.org/10.1182/blood-2006-02-004812

Published: 2006

Journal Articles

Correction of β Thalassemia by Homologous Recombination in Embryonic Stem Cells.

Thomas M. Ryan, Ph.D., Chiao-Wang Sun, Ph.D., Li-Chen Wu, Jin-Xiang Ren, Tim M. Townes, Ph.D.

Blood (2004) 104 (11): 373.

https://doi.org/10.1182/blood.V104.11.373.373

Published: 2004

Journal Articles

Correction of a mouse model of sickle cell disease: lentiviral/antisickling β-globin gene transduction of unmobilized, purified hematopoietic stem cells

Dana N. Levasseur, Thomas M. Ryan, Kevin M. Pawlik, Tim M. Townes

Blood (2003) 102 (13): 4312–4319.

https://doi.org/10.1182/blood-2003-04-1251

Published: 2003

Includes: Supplemental data

Journal Articles

Targeted disruption of the activating transcription factor 4 gene results in severe fetal anemia in mice

Howard C. Masuoka, Tim M. Townes

Blood (2002) 99 (3): 736–745.

https://doi.org/10.1182/blood.V99.3.736

Published: 2002

NARROW

A Novel Mouse Model of Hemoglobin-SC Disease: Bridging the Knowledge Gap in Sickle Cell Disease

A novel therapeutic strategy for β-thalassemia

Regulation of Hematopoietic Stem Cell Function By the Histone H2A Deubiquitinase Usp16

Suppression of Antioxidant Responses in Dyskeratosis Congenita Cells

Modified IPS Cells for Hemoglobinopathies

Crispr Modification of Induced Pluripotent Stem Derived from Diamond-Blackfan Anemia Fibroblasts

Transcription Activation of an Antisense Long Noncoding RNA (lnc-Mega1) of RBM15 By RUNX1 Enhances Megakaryocyte Differentiation

Targeting KLF1 for the Treatment of Sickle Cell Disease Using Antisense Oligonucleotides

Targeting BCL11A and KLF1 For The Treatment Of Sickle Cell Disease and β-Thalassemia In Vitro using Antisense Oligonucleotides

Role Of Dpy30/MLL Complexes In Regulating Hematopoietic Progenitor Cell Maintenance and Differentiation

Heme-regulated eIF2α kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis

Preclinical Studies for Sickle Cell Disease Gene Therapy Using Bone Marrow CD34+ Cells Modified with a βAS3-Globin Lentiviral Vector

Genome-Wide Analysis of EKLF Occupancy in Erythroid Chromatin Reveals 5′, 3′ and Intragenic Binding Sites in EKLF Target Genes

Correction of sickle cell disease by homologous recombination in embryonic stem cells

Correction of β Thalassemia by Homologous Recombination in Embryonic Stem Cells.

Correction of a mouse model of sickle cell disease: lentiviral/antisickling β-globin gene transduction of unmobilized, purified hematopoietic stem cells

Targeted disruption of the activating transcription factor 4 gene results in severe fetal anemia in mice

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American Society of Hematology

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ASH Publications

American Society of Hematology

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