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Martin H Steinberg
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Journal Articles

Mean Corpuscular Hemoglobin Is an Important Modulator of HbF/F-Cell and Response to Gene Therapy and Hydroxyurea in Sickle Cell Disease

Martin H. Steinberg, Carlo Brugnara, Abdullah Kutlar, Paola Sebastiani
Journal: Blood
Blood (2024) 144 (Supplement 1): 5274.
https://doi.org/10.1182/blood-2024-205808
Published: 2024
Journal Articles

Durable Clinical Benefits with Exagamglogene Autotemcel for Severe Sickle Cell Disease

Haydar Frangoul, Franco Locatelli, Akshay Sharma, Monica Bhatia, Markus Y Mapara, Robert I. Liem, Donna Wall, Lyndsay Molinari, Laurence Dedeken, Kevin H.M. Kuo, Paul Telfer, Ami J. Shah, Marina Cavazzana, Selim Corbacioglu, Michael J. Eckrich, Damiano Rondelli, Roland Meisel, Stephan Lobitz, Mariane De Montalembert, Martin H. Steinberg, Mark C. Walters, Laura Bower, Suzan Imren, Tina Liu, Weiyu Zhou, William Hobbs, Stephan A. Grupp
Journal: Blood
Blood (2024) 144 (Supplement 1): 4954.
https://doi.org/10.1182/blood-2024-204001
Published: 2024
Journal Articles

Single Cell Hemoglobin Quantification Reveals HbF and HbS Increases in Sickle Erythrocytes from Patients Treated with Hydroxyurea

Laura Bencheikh, Laura Matabishi-Bibi, Gabriela Luszczewska, Meghan Perkins, Nicolas Hebert, Nagamy Rose Balli, Yosr Zaouali, Vincent Malcor Deydier De Pierrefeu, Fatima Bensiradj, Caroline Barau, France Pirenne, Carlo Brugnara, Martin H. Steinberg, Haydar Frangoul, Marie Cambot, Pablo Bartolucci
Journal: Blood
Blood (2024) 144 (Supplement 1): 1105.
https://doi.org/10.1182/blood-2024-209868
Published: 2024
Journal Articles

Exagamglogene Autotemcel for Severe Sickle Cell Disease

Haydar Frangoul, Franco Locatelli, Akshay Sharma, Monica Bhatia, Markus Mapara, Lyndsay Molinari, Donna Wall, Robert I. Liem, Paul Telfer, Ami J. Shah, Marina Cavazzana, Selim Corbacioglu, Damiano Rondelli, Roland Meisel, Laurence Dedeken, Stephan Lobitz, Mariane de Montalembert, Martin H. Steinberg, Mark C. Walters, Laura Bower, Suzan Imren, Christopher Simard, Fengjuan Xuan, Weiyu Zhou, Phuong Khanh Morrow, William Hobbs, Stephan Grupp
Journal: Blood
Blood (2023) 142 (Supplement 1): 1052.
https://doi.org/10.1182/blood-2023-190139
Published: 2023
Journal Articles

SR-18292 Induces Fetal Hemoglobin Synthesis and Reduces Disease Pathology in Sickle Cell Mice

Yanan Sun, Hajar Benmhammed, Alawi Habara, Martin H. Steinberg, Shuaiying Cui
Journal: Blood
Blood (2023) 142 (Supplement 1): 5258.
https://doi.org/10.1182/blood-2023-186314
Published: 2023
Journal Articles

Fetal hemoglobin in sickle cell anemia

Martin H. Steinberg
Journal: Blood
Blood (2020) 136 (21): 2392–2400.
https://doi.org/10.1182/blood.2020007645
Published: 2020
Journal Articles

Safety and Efficacy of CTX001 in Patients with Transfusion-Dependent β-Thalassemia and Sickle Cell Disease: Early Results from the Climb THAL-111 and Climb SCD-121 Studies of Autologous CRISPR-CAS9-Modified CD34+ Hematopoietic Stem and Progenitor Cells

Haydar Frangoul, MD, Yael Bobruff, PhD, Maria Domenica Cappellini, Selim Corbacioglu, MD, Christine Marie Fernandez, RN,MSN, Josu de la Fuente, Stephan A Grupp, MD PhD, Rupert Handgretinger, MD, Tony W. Ho, MD, Suzan Imren, MD, Antonis Kattamis, Julie Lekstrom-Himes, MD, Franco Locatelli, MD PhD, Yimeng Lu, PhD, Markus Y Mapara, MD PhD, Mariane de Montalembert, MD PhD, Sarah D. Mulcahey, MS, Damiano Rondelli, MD, Niraj Shanbhag, MD PhD, Sujit Sheth, MD, Sandeep Soni, MBBS, Martin H. Steinberg, MD, Michael J. Weinstein, John K. Wu, MBBS, FRCPC, MS, Donna Wall, MDCCPE
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
https://doi.org/10.1182/blood-2020-139575
Published: 2020
Journal Articles

Targeting Transcriptional Co-Activator PGC-1a for the Treatment of Sickle Cell Disease

Alawi Habara, MBBS, MSc, Cuong LE, PhD, David H.K. Chui, MD, Martin H. Steinberg, MD, Shuaiying Cui, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2254.
https://doi.org/10.1182/blood-2019-123959
Published: 2019
Journal Articles

Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis

Cuong Quang Le, Greggory Myers, Alawi Habara, Natee Jearawiriyapaisarn, George J. Murphy, David H. K. Chui, Martin H. Steinberg, James Douglas Engel, Shuaiying Cui
Journal: Blood
Blood (2019) 133 (22): 2455–2459.
https://doi.org/10.1182/blood.2018892737
Published: 2019
Includes: Supplemental data
Journal Articles

Primary polymerization prevention

Clinical Trials & Observations
Martin H Steinberg
Journal: Blood
Blood (2019) 133 (17): 1797–1798.
https://doi.org/10.1182/blood-2019-02-898767
Published: 2019
Journal Articles

Regulating Transcriptional Co-Activator PGC-1α for the Treatment of Sickle Cell Disease

Alawi Habara, MBBS, MSc, Cuong LE, PhD, George J Murphy, PhD, David H.K. Chui, MD, Martin H. Steinberg, MD, Shuaiying Cui, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2358.
https://doi.org/10.1182/blood-2018-99-111022
Published: 2018
Journal Articles

LSD1 Inhibitors Induce Fetal Hemoglobin in Primary Human Erythroid Cells

Cuong LE, PhD, Greggory Myers, Alawi Habara, MBBS, MSc, David H.K. Chui, MD, Martin H. Steinberg, MD, James Douglas Engel, PhD, Shuaiying Cui, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1066.
https://doi.org/10.1182/blood-2018-99-117675
Published: 2018
Journal Articles

Biomarker Signatures of Sickle Cell Disease Severity

Mengtian Du, BA, Sarah Van Ness, BA, Victor R. Gordeuk, MD, Mark T Gladwin, MD, Paola Sebastiani, PhD, Martin H. Steinberg, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 690.
https://doi.org/10.1182/blood.V130.Suppl_1.690.690
Published: 2017
Journal Articles

Induced Pluripotent Stem Cell (iPSC)-Based Mapping of Globin Expression throughout Human Erythropoietic Development

Kim Vanuytsel, PhD, Taylor Matte, Amy Leung, PhD, Zaw Htut Naing, Tasha A. Morrison, MPH,BA, David H.K. Chui, MD, Martin H. Steinberg, MD, George J Murphy, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 946.
https://doi.org/10.1182/blood.V130.Suppl_1.946.946
Published: 2017
Journal Articles

SIRT1 Increases the Expression of Fetal Hemoglobin Genes in Human Adult and Cord Blood Erythroblasts

Yan Dai, PhD, Tyngwei Chen, Heba Ijaz, Elizabeth Cho, Ryo Kurita, PhD, Yukio Nakamura, MD PhD, Martin H. Steinberg, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 287.
https://doi.org/10.1182/blood.V130.Suppl_1.287.287
Published: 2017
Journal Articles

A Long Noncoding RNA from the HBS1L-MYB Intergenic Region on Chr6q23 Regulates Human Fetal Hemoglobin Expression

Tasha A. Morrison, MPH,BA, Ibifiri Wilcox, BS, Hong-Yuan Luo, PhD, John Farrell, PhD, Ryo Kurita, PhD, Yukio Nakamura, MD PhD, George J Murphy, PhD, Shuaiying Cui, PhD, Martin H. Steinberg, MD, David H.K. Chui, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 288.
https://doi.org/10.1182/blood.V130.Suppl_1.288.288
Published: 2017
Journal Articles

In Vivo Effects of LSD1 Inhibition By Small Chemical Inhibitors in Sickle Cell Mice

Cuong Le, PhD, Greggory Myers, Alawi Habara, Natee Jearawiriyapaisarn, PhD, Mary Lee, PhD, David H.K. Chui, MD, Martin H. Steinberg, MD, James Engel, PhD, Shuaiying Cui, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 968.
https://doi.org/10.1182/blood.V130.Suppl_1.968.968
Published: 2017
Journal Articles

Genome-wide association study to identify variants associated with acute severe vaso-occlusive pain in sickle cell anemia

Shruti Chaturvedi, Pallav Bhatnagar, Christopher J. Bean, Martin H. Steinberg, Jaqueline N. Milton, James F. Casella, Emily Barron-Casella, Dan E. Arking, Michael R. DeBaun
Journal: Blood
Blood (2017) 130 (5): 686–688.
https://doi.org/10.1182/blood-2017-02-769661
Published: 2017
Includes: Supplemental data
Journal Articles

A Library of Sickle Cell Anemia Induced Pluripotent Stem Cells of Diverse Haplotypes and Ethnicities

Seonmi Park, Andreia Gianotti-Sommer, David H.K. Chui, MD, Maria Stella Figueiredo, MDPhD, Abdulrahman Alsultan, MD, Amein Al-Ali, Martin H Steinberg, Professor, of, MDcine, George J. Murphy, PhD, Gustavo Mostoslavsky
Journal: Blood
Blood (2015) 126 (23): 2354.
https://doi.org/10.1182/blood.V126.23.2354.2354
Published: 2015
Journal Articles

Polymorphisms Associated with the Arab-Indian Haplotype of Sickle Cell Anemia Are Candidate Fetal Hemoglobin Gene Modulators

Vinod Vathipadiekal, PhD, Abdulrahman Alsultan, MD, John Farrell, PhD, A.M Al-Rubaish, Fahad Al-Muhanna, Z Naserullah, A Alsuliman, P.K. Patra, Jacqueline Milton, Lindsay Farrer, David H.K. Chui, MD, Amein Al-Ali, Paola Sebastiani, PhD, Martin H. Steinberg, MD
Journal: Blood
Blood (2015) 126 (23): 3388.
https://doi.org/10.1182/blood.V126.23.3388.3388
Published: 2015