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David H. K. Chui
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Journal Articles

Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis

Cuong Quang Le, Greggory Myers, Alawi Habara, Natee Jearawiriyapaisarn, George J. Murphy, David H. K. Chui, Martin H. Steinberg, James Douglas Engel, Shuaiying Cui
Journal: Blood
Blood (2019) 133 (22): 2455–2459.
https://doi.org/10.1182/blood.2018892737
Published: 2019
Includes: Supplemental data
Journal Articles

Editing aberrant splice sites efficiently restores β-globin expression in β-thalassemia

Brief Report
Shuqian Xu, Kevin Luk, Qiuming Yao, Anne H. Shen, Jing Zeng, Yuxuan Wu, Hong-Yuan Luo, Christian Brendel, Luca Pinello, David H. K. Chui, Scot A. Wolfe, Daniel E. Bauer
Journal: Blood
Blood (2019) 133 (21): 2255–2262.
https://doi.org/10.1182/blood-2019-01-895094
Published: 2019
Includes: Supplemental data
Journal Articles

A phase 2 trial of HQK-1001 in HbE-β thalassemia demonstrates HbF induction and reduced anemia

Clinical Trials & Observations
Poramin Patthamalai, Suthat Fuchareon, Nattawara Chaneiam, Richard G. Ghalie, David H. K. Chui, Michael S. Boosalis, Susan P. Perrine
Journal: Blood
Blood (2014) 123 (12): 1956–1957.
https://doi.org/10.1182/blood-2013-11-538470
Published: 2014
Journal Articles

Fetal hemoglobin in sickle cell anemia: a glass half full?

Martin H. Steinberg, David H. K. Chui, George J. Dover, Paola Sebastiani, Abdulrahman Alsultan
Journal: Blood
Blood (2014) 123 (4): 481–485.
https://doi.org/10.1182/blood-2013-09-528067
Published: 2014
Journal Articles

HbC disorders

Martin H. Steinberg, David H. K. Chui
Journal: Blood
Blood (2013) 122 (22): 3698.
https://doi.org/10.1182/blood-2013-09-526764
Published: 2013
Journal Articles

The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation

Brenden W. Smith, Sarah S. Rozelle, Amy Leung, Jessalyn Ubellacker, Ashley Parks, Shirley K. Nah, Deborah French, Paul Gadue, Stefano Monti, David H. K. Chui, Martin H. Steinberg, Andrew L. Frelinger, Alan D. Michelson, Roger Theberge, Mark E. McComb, Catherine E. Costello, Darrell N. Kotton, Gustavo Mostoslavsky, David H. Sherr, George J. Murphy
Journal: Blood
Blood (2013) 122 (3): 376–385.
https://doi.org/10.1182/blood-2012-11-466722
Published: 2013
Includes: Supplemental data
Journal Articles

Fetal hemoglobin in sickle cell anemia

Idowu Akinsheye, Abdulrahman Alsultan, Nadia Solovieff, Duyen Ngo, Clinton T. Baldwin, Paola Sebastiani, David H. K. Chui, Martin H. Steinberg
Journal: Blood
Blood (2011) 118 (1): 19–27.
https://doi.org/10.1182/blood-2011-03-325258
Published: 2011
Includes: Supplemental data
Journal Articles

A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression

John J. Farrell, Richard M. Sherva, Zhi-yi Chen, Hong-yuan Luo, Benjamin F. Chu, Shau Yin Ha, Chi Kong Li, Anselm C. W. Lee, Rever C. H. Li, Chi Keung Li, Hui Leung Yuen, Jason C. C. So, Edmond S. K. Ma, Li Chong Chan, Vivian Chan, Paola Sebastiani, Lindsay A. Farrer, Clinton T. Baldwin, Martin H. Steinberg, David H. K. Chui
Journal: Blood
Blood (2011) 117 (18): 4935–4945.
https://doi.org/10.1182/blood-2010-11-317081
Published: 2011
Includes: Supplemental data
Journal Articles

Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5′ olfactory receptor gene cluster

Nadia Solovieff, Jacqueline N. Milton, Stephen W. Hartley, Richard Sherva, Paola Sebastiani, Daniel A. Dworkis, Elizabeth S. Klings, Lindsay A. Farrer, Melanie E. Garrett, Allison Ashley-Koch, Marilyn J. Telen, Supan Fucharoen, Shau Yin Ha, Chi-Kong Li, David H. K. Chui, Clinton T. Baldwin, Martin H. Steinberg
Journal: Blood
Blood (2010) 115 (9): 1815–1822.
https://doi.org/10.1182/blood-2009-08-239517
Published: 2010
Journal Articles

THAL for THAL?

David H. K. Chui
Journal: Blood
Blood (2007) 110 (8): 2788–2789.
https://doi.org/10.1182/blood-2007-08-102913
Published: 2007
Journal Articles

α4-Integrin + endothelium derived from primate embryonic stem cells generates primitive and definitive hematopoietic cells

Gen Shinoda, Katsutsugu Umeda, Toshio Heike, Masato Arai, Akira Niwa, Feng Ma, Hirofumi Suemori, Hong Yuan Luo, David H. K. Chui, Ryuzo Torii, Masabumi Shibuya, Norio Nakatsuji, Tatsutoshi Nakahata
Journal: Blood
Blood (2006) 109 (6): 2406–2415.
https://doi.org/10.1182/blood-2006-06-031039
Published: 2006
Includes: Supplemental data
Journal Articles

Screening and counseling for thalassemia

David H. K. Chui, Melody J. Cunningham, Hong-yuan Luo, Lawrence C. Wolfe, Ellis J. Neufeld, Martin H. Steinberg
Journal: Blood
Blood (2006) 107 (4): 1735–1737.
https://doi.org/10.1182/blood-2005-09-3557
Published: 2006
Journal Articles

Patients with thalassemia in the United States

Hong-yuan Luo, Jeanne Boudreaux, Martin H. Steinberg, David H. K. Chui
Journal: Blood
Blood (2005) 105 (12): 4896–4897.
https://doi.org/10.1182/blood-2005-03-0856
Published: 2005
Journal Articles

Hemoglobin H disease: not necessarily a benign disorder

Clinical Trials & Observations
David H. K. Chui, Suthat Fucharoen, Vivian Chan
Journal: Blood
Blood (2003) 101 (3): 791–800.
https://doi.org/10.1182/blood-2002-07-1975
Published: 2003