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Journal Articles

One hundred thirty-four germ line PU.1 variants and the agammaglobulinemic patients carrying them

Ainsley V. C. Knox, Lauren Y. Cominsky, Di Sun, Emylette Cruz Cabrera, Brian E. Nolan, Edann Ofray, Elisa Benetti, Camilla Visconti, Federica Barzaghi, Sergio D. Rosenzweig, Monica G. Lawrence, Kathleen E. Sullivan, Samuel Yoon, Suzanna Rachimi, Nurcicek Padem, Erin Conboy, Maja Stojanovic, Gordana Petrovic, Srdjan Pasic, Joseph Church, Ronald M. Ferdman, Fabio Candotti, Tiphaine Arlabosse, Katerina Theodoropoulou, Cullen M. Dutmer, László Maródi, Gabriella Szücs, Arnon Broides, Amit Nahum, Jacov Levy, Kaisa Kettunen, Ravindra Daddali, Mikko Seppänen, Markku Vänttinen, Timi Martelius, Juha Grönholm, Matilde Peri, Chiara Azzari, Silvia Ricci, Samar Ojaimi, Emily S. J. Edwards, Menno C. van Zelm, Jinqiao Sun, Hassan Abolhassani, Qiang Pan-Hammarström, Hakon Hakonarson, Daniel Mayr, Kaan Boztug, Bertrand Boisson, Jean-Laurent Casanova, Carole Le Coz, Gregory M. K. Poon, Neil Romberg

Blood (2025) 145 (22): 2549–2560.

https://doi.org/10.1182/blood.2024026683

Published: 2025

Includes: Supplemental data

Journal Articles

A TIM-3–Fc decoy secreted by engineered T cells improves CD19 CAR T-cell therapy in B-cell acute lymphoblastic leukemia

Blood (2025) 145 (22): 2599–2613.

https://doi.org/10.1182/blood.2024025440

Published: 2025

Includes: Supplemental data

Journal Articles

Integrative genomic analysis of DLBCL identifies immune environments associated with bispecific antibody response

Blood (2025) 145 (21): 2460–2472.

https://doi.org/10.1182/blood.2024025355

Published: 2025

Includes: Supplemental data

Journal Articles

Up-front blinatumomab improves MRD clearance and outcome in adult Ph – B-lineage ALL: the GIMEMA LAL2317 phase 2 study

Blood (2025) 145 (21): 2447–2459.

https://doi.org/10.1182/blood.2024027500

Published: 2025

Includes: Supplemental data

Journal Articles

Imaging Mass Cytometry Reveals the Order of Events in the Pathogenesis of Immune-Mediated Aplastic Anemia

Emma S. Pool, Sietse J. Luk, Marieke E. IJsselsteijn, Vincent van Unen, Noel F.C.C. de Miranda, J.H. Frederik Falkenburg, Frits Koning, Mirjam H.M. Heemskerk, Jennifer M-L. Tjon

Blood blood.2025028723.

https://doi.org/10.1182/blood.2025028723

Published: 2025

Includes: Supplemental data

Journal Articles

Modeling the HLH immune synapse uncovers critical roles for IS termination, cytokine intensity, and target cell death

Anastasia M. Frank-Kamenetskii, Hannah Klinghoffer, Jemy Anna Varghese, Vinh Dang, Jeremy Morrissette, Joseph A. Fraietta, Caroline Diorio, Janis K. Burkhardt, Scott Canna

Blood blood.2024027179.

https://doi.org/10.1182/blood.2024027179

Published: 2025

Includes: Multimedia, Supplemental data

Journal Articles

Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells

Blood blood.2024025536.

https://doi.org/10.1182/blood.2024025536

Published: 2025

Includes: Supplemental data

Journal Articles

The JAK2 46/1 haplotype influences PD-L1 expression

Gonzalo Carreño-Tarragona, María Tiana, Raquel Rouco, Alejandra Leivas, Jesús Victorino, Roberto García-Vicente, Andrew J. Chase, Andrea Maidana, William J. Tapper, Rosa Ayala, Nicholas C. P. Cross, Joaquín Martínez-López, Miguel Manzanares

Blood (2025) 145 (19): 2196–2201.

https://doi.org/10.1182/blood.2023023787

Published: 2025

Includes: Supplemental data

Journal Articles

Defining pathogenic IL-17 and CSF-1 gene expression signatures in chronic graft-versus-host disease

Julie R. Boiko, Kathleen S. Ensbey, Olivia G. Waltner, Isaac C. Jenkins, Shruti S. Bhise, Kelli P. A. MacDonald, Bruce R. Blazar, A. Marcie Hall, Ted A. Gooley, Simone A. Minnie, Stephanie J. Lee, Scott N. Furlan, Geoffrey R. Hill

Blood (2025) 145 (19): 2214–2228.

https://doi.org/10.1182/blood.2024025337

Published: 2025

Includes: Supplemental data

Journal Articles

STING activation improves T-cell-engaging immunotherapy for acute myeloid leukemia

Andreas Linder, Daniel Nixdorf, Niklas Kuhl, Ignazio Piseddu, TengTeng Xu, Anne V. Holtermann, Gunnar Kuut, Rebekka Endres, Nora Philipp, Veit Bücklein, Johann de Graaff, Thomas Carell, Sebastian Kobold, Roman Kischel, Veit Hornung, Marion Subklewe

Blood (2025) 145 (19): 2149–2160.

https://doi.org/10.1182/blood.2024026934

Published: 2025

Includes: Supplemental data

Journal Articles

Reactive oxygen species regulate early development of the intestinal macrophage-microbiome interface

Zohreh Mansoori Moghadam, Bei Zhao, Candice Raynaud, Valentina Strohmeier, Jana Neuber, Anne Kathrin Lösslein, Sabrina Qureshi, Vitka Gres, Tara Ziegelbauer, Sebastian Baasch, Christoph Schell, Klaus Warnatz, Naohiro Inohara, Gabriel Nuñez, Thomas Clavel, Stephan P. Rosshart, Julia Kolter, Philipp Henneke

Blood (2025) 145 (18): 2025–2040.

https://doi.org/10.1182/blood.2024025240

Published: 2025

Includes: Supplemental data

Journal Articles

Donor regulatory T-cell therapy to prevent graft-versus-host disease

Blood (2025) 145 (18): 2012–2024.

https://doi.org/10.1182/blood.2024026446

Published: 2025

Includes: Supplemental data

Journal Articles

CAR T cells in autoimmunity: game changer or stepping stone?

Dimitrios Mougiakakos, Everett H. Meyer, Georg Schett

Blood (2025) 145 (17): 1841–1849.

https://doi.org/10.1182/blood.2024025413

Published: 2025

Includes: Supplemental data

Journal Articles

Common hereditary variants of the APOE gene and posttransplant outcome in acute myeloid leukemia

Blood (2025) 145 (17): 1943–1956.

https://doi.org/10.1182/blood.2024026886

Published: 2025

Includes: Supplemental data

Journal Articles

Emerging biomarkers for CD3×CD20 bispecific antibodies in lymphoma

Cameron S. Lewis, Allison Barraclough, Eliza A. Hawkes

Blood (2025) 145 (17): 1850–1857.

https://doi.org/10.1182/blood.2024025772

Published: 2025

Journal Articles

T-ICAHT: Grading and Prognostic Impact of Thrombocytopenia After CAR T-cell Therapy

Blood blood.2025028833.

https://doi.org/10.1182/blood.2025028833

Published: 2025

Includes: Supplemental data

Journal Articles

HSP-CAR30 with a high proportion of less-differentiated T cells promotes durable responses in refractory CD30 + lymphoma

Ana Carolina Caballero, Cristina Ujaldón-Miró, Paula Pujol-Fernández, Rosanna Montserrat-Torres, Maria Guardiola-Perello, Eva Escudero-López, Irene Garcia-Cadenas, Albert Esquirol, Rodrigo Martino, Paola Jara-Bustamante, Pol Ezquerra, José Manuel Soria, Eva Iranzo, Maria-Estela Moreno-Martinez, Mireia Riba, Jorge Sierra, Carmen Alvarez-Fernández, Laura Escribà-Garcia, Javier Briones

Blood (2025) 145 (16): 1788–1801.

https://doi.org/10.1182/blood.2024026758

Published: 2025

Includes: Supplemental data

Journal Articles

Tumor burden quantified by soluble B-cell maturation antigen and metabolic tumor volume determines myeloma CAR-T outcomes

Blood (2025) 145 (15): 1645–1657.

https://doi.org/10.1182/blood.2024024965

Published: 2025

Includes: Supplemental data

Journal Articles

How I Treat Wiskott-Aldrich syndrome

Tanja C Vallée, Michael H Albert, Sung-Yun Pai

Blood blood.2024026288.

https://doi.org/10.1182/blood.2024026288

Published: 2025

Includes: Supplemental data

Journal Articles

High-throughput drug screening identifies SMAC mimetics as enhancers of NK-cell cytotoxicity in chronic myeloid leukemia

Petra Nygrén, Jonas Bouhlal, Emmi Jokinen, Sofia Forstén, Essi Laajala, Diogo Dias, Shady Adnan-Awad, Aleksandr Ianevski, Jay Klievink, Hanna Lähteenmäki, Heikki Kuusanmäki, Mikko Myllymäki, Tiina Kasanen, Khalid Saeed, Dean A. Lee, Henrik Hjorth-Hansen, Tero Aittokallio, Olli Dufva, Satu Mustjoki

Blood (2025) 145 (15): 1670–1686.

https://doi.org/10.1182/blood.2024025286

Published: 2025

Includes: Supplemental data

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One hundred thirty-four germ line PU.1 variants and the agammaglobulinemic patients carrying them

A TIM-3–Fc decoy secreted by engineered T cells improves CD19 CAR T-cell therapy in B-cell acute lymphoblastic leukemia

Integrative genomic analysis of DLBCL identifies immune environments associated with bispecific antibody response

Up-front blinatumomab improves MRD clearance and outcome in adult Ph – B-lineage ALL: the GIMEMA LAL2317 phase 2 study

Imaging Mass Cytometry Reveals the Order of Events in the Pathogenesis of Immune-Mediated Aplastic Anemia

Modeling the HLH immune synapse uncovers critical roles for IS termination, cytokine intensity, and target cell death

Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells

The JAK2 46/1 haplotype influences PD-L1 expression

Defining pathogenic IL-17 and CSF-1 gene expression signatures in chronic graft-versus-host disease

STING activation improves T-cell-engaging immunotherapy for acute myeloid leukemia

Reactive oxygen species regulate early development of the intestinal macrophage-microbiome interface

Donor regulatory T-cell therapy to prevent graft-versus-host disease

CAR T cells in autoimmunity: game changer or stepping stone?

Common hereditary variants of the APOE gene and posttransplant outcome in acute myeloid leukemia

Emerging biomarkers for CD3×CD20 bispecific antibodies in lymphoma

T-ICAHT: Grading and Prognostic Impact of Thrombocytopenia After CAR T-cell Therapy

HSP-CAR30 with a high proportion of less-differentiated T cells promotes durable responses in refractory CD30 + lymphoma

Tumor burden quantified by soluble B-cell maturation antigen and metabolic tumor volume determines myeloma CAR-T outcomes

How I Treat Wiskott-Aldrich syndrome

High-throughput drug screening identifies SMAC mimetics as enhancers of NK-cell cytotoxicity in chronic myeloid leukemia

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