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Journal Articles

Clinical phenotype and pathophysiological mechanisms underlying qualitative Low VWF

Open Access
Ferdows Atiq, Robin Blok, Calvin van Kwawegen, Anne-Marije Hulshof, Dearbhla Doherty, Michelle Lavin, Johanna G van der Bom, Niamh M O'Connell, Joke de Meris, Kevin Ryan, Saskia E.M. Schols, Waander L. van Heerde, Mairead M Doyle, Mary B Byrne, Floor C.J.I. Heubel-Moenen, Karin P.M. van Galen, Roger J.S. Preston, Marjon H. Cnossen, Karin Fijnvandraat, Prof, Ross Ian Baker, Karina Meijer, Paula D. James, Jorge Di Paola, Jeroen C.J. Eikenboom, Frank W.G. Leebeek, James S. O'Donnell
Journal: Blood
Blood blood.2024028035.
https://doi.org/10.1182/blood.2024028035
Published: 2025
Includes: Supplemental data
Journal Articles

Enhanced α2-3 linked sialylation determines the extended half-life of CHO-rVWF

Open Access
Ciara Byrne, Soracha Ward, Jamie M O'Sullivan, Alain Chan Kwo Chion, Patricia Lopes, Bogdan Baci, Caoimhe Dowd, Darragh Jordan, Ross Ian Baker, Roger . Preston, Marco Monopoli, Peter L Turecek, Maximilianos Kotsias, Jack Cheeseman, Alan Moran, Richard A Gardner, Daniel I R Spencer, Ferdows Atiq, James S. O'Donnell
Journal: Blood
Blood blood.2024027038.
https://doi.org/10.1182/blood.2024027038
Published: 2025
Includes: Supplemental data
Journal Articles

Whole Genome Sequencing to Elucidate Genetic Modifiers of FVIII Clearance Heterogeneity in Patients with Hemophilia a

Free
Anne-Marije Hulshof, Lilian Antunes Heck, Ferdows Atiq, Einas Elsheikh, Claire Kelly, Michelle Lavin, Niamh Larkin, Niamh O'Connell, Kevin Ryan, Mary Byrne, Peter Turecek, Jorge Di Paola, James O'Donnell
Journal: Blood
Blood (2024) 144 (Supplement 1): 3958.
https://doi.org/10.1182/blood-2024-204546
Published: 2024
Journal Articles

The aptamer BT200 blocks interaction of K1405-K1408 in the VWF-A1 domain with macrophage LRP1

Free
Alain Chion, Ciara Byrne, Ferdows Atiq, Dearbhla Doherty, Sonia Aguila, Judicael Fazavana, Patricia Lopes, Ellie Karampini, Aamir Amin, Roger J. S. Preston, Ross I. Baker, Thomas A. J. McKinnon, Shuhao Zhu, James C. Gilbert, Jonas Emsley, Bernd Jilma, James S. O’Donnell
Journal: Blood
Blood (2024) 144 (13): 1445–1456.
https://doi.org/10.1182/blood.2024024055
Published: 2024
Includes: Supplemental data
Journal Articles

Novel functions for von Willebrand factor

Available to Purchase
Ferdows Atiq, James S. O’Donnell
Journal: Blood
Blood (2024) 144 (12): 1247–1256.
https://doi.org/10.1182/blood.2023021915
Published: 2024
Includes: Supplemental data
Journal Articles

Type 1 VWD classification revisited: novel insights from combined analysis of the LoVIC and WiN studies

Free
Ferdows Atiq, Robin Blok, Calvin B. van Kwawegen, Dearbhla Doherty, Michelle Lavin, Johanna G. van der Bom, Niamh M. O'Connell, Joke de Meris, Kevin Ryan, Saskia E. M. Schols, Mary Byrne, Floor C. J. I. Heubel-Moenen, Karin P. M. van Galen, Roger J. S. Preston, Marjon H. Cnossen, Karin Fijnvandraat, Ross I. Baker, Karina Meijer, Paula James, Jorge Di Paola, Jeroen Eikenboom, Frank W. G. Leebeek, James S. O'Donnell
Journal: Blood
Blood (2024) 143 (14): 1414–1424.
https://doi.org/10.1182/blood.2023022457
Published: 2024
Includes: Supplemental data
Journal Articles

Age Regulates Desmopressin Responses in Patients with Low Von Willebrand Factor and Type 1 Von Willebrand Disease in the Lovic and Win Studies

Free
Ferdows Atiq, Robin Blok, Calvin Van Kwawegen, Dearbhla Doherty, Michelle Lavin, Johanna G. Van Der Bom, Niamh O'Connell, Joke De Meris, Kevin Ryan, Saskia Schols, Mary Byrne, Floor Moenen, Karin PM Van Galen, Roger J.S Preston, Karin Fijnvandraat, Ross Baker, Karina Meijer, Paula James, Jorge Di Paola, Jeroen Eikenboom, James S. O'Donnell, Frank W.G. Leebeek
Journal: Blood
Blood (2023) 142 (Supplement 1): 510.
https://doi.org/10.1182/blood-2023-184734
Published: 2023
Journal Articles

The Relationship between Low Von Willebrand Factor, Type 1 Von Willebrand Disease and Ageing - Novel Insights from the Lovic and Win Cohort Studies

Free
Ferdows Atiq, Robin Blok, Calvin Van Kwawegen, Dearbhla Doherty, Michelle Lavin, Johanna G. Van Der Bom, Niamh O'Connell, Joke De Meris, Kevin Ryan, Saskia Schols, Mary Byrne, Floor Moenen, Karin PM Van Galen, Roger J.S Preston, Karin Fijnvandraat, Ross Baker, Karina Meijer, Paula James, Jorge Di Paola, Jeroen Eikenboom, Frank W.G. Leebeek, James S. O'Donnell
Journal: Blood
Blood (2023) 142 (Supplement 1): 509.
https://doi.org/10.1182/blood-2023-181603
Published: 2023
Journal Articles

Low Von Willebrand Factor: Cut-Off Value for Diagnosis and Risk Score to Predict Bleeding Incidence

Free
Ferdows Atiq, Esmee Wuijster, BSc, Moniek P.M. de Maat, PhD, Marieke J.H.A. Kruip, MD PhD, Marjon H. Cnossen, MD PhD, Frank W.G. Leebeek, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–19.
https://doi.org/10.1182/blood-2020-142375
Published: 2020
Journal Articles

Semiautomatic VWF Multimer Densitometric Analysis: Validation of the Clinical Accuracy and Clinical Implications in Von Willebrand Disease

Free
Ferdows Atiq, Johan Boender, MD, Marjon H. Cnossen, MD PhD, Johanna G van der Bom, MD PhD, Karin Fijnvandraat, MD PhD, Joke de Meris, Moniek P.M. de Maat, PhD, Karin P.M. Van Galen, MD MSc, PhD, Britta A.P. Laros-Van Gorkom, MD PhD, Karina Meijer, MD PhD, Jeroen C.J. Eikenboom, MD PhD, Frank W.G. Leebeek, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–16.
https://doi.org/10.1182/blood-2020-142287
Published: 2020
Journal Articles

VWF and FVIII Levels after Desmopressin Are Associated with the Bleeding Phenotype in Type 1 VWD

Free
Ferdows Atiq, Lisette M. Schütte, MD, Agnes E.M. Looijen, Bsc, Johan Boender, MD, Moniek P.M. de Maat, PhD, Marieke J.H.A. Kruip, MD PhD, Frank W.G. Leebeek, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1116.
https://doi.org/10.1182/blood-2019-123634
Published: 2019