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Journal Articles

The aptamer BT200 blocks interaction of K1405-K1408 in the VWF-A1 domain with macrophage LRP1

Alain Chion, Ciara Byrne, Ferdows Atiq, Dearbhla Doherty, Sonia Aguila, Judicael Fazavana, Patricia Lopes, Ellie Karampini, Aamir Amin, Roger J. S. Preston, Ross I. Baker, Thomas A. J. McKinnon, Shuhao Zhu, James C. Gilbert, Jonas Emsley, Bernd Jilma, James S. O’Donnell

Blood (2024) 144 (13): 1445–1456.

https://doi.org/10.1182/blood.2024024055

Published: 2024

Includes: Supplemental data

Journal Articles

Thrombogenesis Mechanisms of High Doses of Ponatinib in Patients with Chronic Myeloid Leukemia (CML) Compared to Tyrosine Kinase Inhibitors

Blood (2022) 140 (Supplement 1): 6730–6732.

https://doi.org/10.1182/blood-2022-163070

Published: 2022

Journal Articles

Hydroxyurea Reduces Neutrophil Extracellular Trap Formation in Myeloproliferative Neoplasms

Ernesto J Cuenca, Nieves García Gisbert, BSc, Ascensión M de Los Reyes-García, PhDStudent, Cristina Aroca, MD, Lorena Martinez-Montesinos, MD, Marcio Andrade, MD PhD, Sonia Aguila, PhD, Pedro J Guijarro-Carrillo, Rosa Cifuentes-Riquelme, PhDStudent, Rocio González-Conejero, PhD, Constantino Martínez, PhD, Vicente Vicente, MD PhD, Alberto Alvarez-Larrán, MD, Beatriz Bellosillo, PhD, Raul Teruel-Montoya, PhD, Francisca Ferrer Marin, MD PhD

Blood (2020) 136 (Supplement 1): 20–21.

https://doi.org/10.1182/blood-2020-139368

Published: 2020

Journal Articles

TNF-α–driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging

Blood (2019) 134 (9): 727–740.

https://doi.org/10.1182/blood.2019000200

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

Increased galactose expression and enhanced clearance in patients with low von Willebrand factor

Sonia Aguila, Michelle Lavin, Niall Dalton, Sean Patmore, Alain Chion, George D. Trahan, Kenneth L. Jones, Catriona Keenan, Teresa M. Brophy, Niamh M. O’Connell, Kevin Ryan, Mary Byrne, Margaret Nolan, Anjali Patel, Roger J. S. Preston, Paula James, Jorge Di Paola, Jamie M. O’Sullivan, James S. O’Donnell

Blood (2019) 133 (14): 1585–1596.

https://doi.org/10.1182/blood-2018-09-874636

Published: 2019

Includes: Supplemental data

Journal Articles

The Low Von Willebrand Factor in Ireland Cohort Study - Defining Optimal Management for Procedures in Patients with Low VWF (30-50 IU/dL)

Dearbhla Doherty, MB, MRCPI, Anjali Patel, Margaret Nolan, Mary Byrne, Sonia Aguila, PhD, Jamie M O'Sullivan, Kevin Ryan, MB, FRCPath, Niamh M O'Connell, MB, PhD FRCPath, Michelle Lavin, MB, PhD FRCPath, James S O'Donnell, MD PhD

Blood (2018) 132 (Supplement 1): 1178.

https://doi.org/10.1182/blood-2018-99-115946

Published: 2018

Journal Articles

TNF-α Driven Inflammation and Mitochondrial Dysfunction Characterize the Platelet Hyperreactivity of Aging and Myeloproliferative Neoplasms (MPN)

Pavel Davizon-Castillo, MD, Brandon McMahon, MD, Sonia Aguila, PhD, Kenneth L. Jones, PhD, George D Trahan, MS, Katrina J. Ashworth, MS, David Bark, PhD, Robert A. Campbell, PhD, Kelly Higa, MS, Lauren Christine Shih, BA, Natalie Saunders, MD, James DeGregori, Matthew T. Rondina, MD, Jorge Di Paola, MD

Blood (2018) 132 (Supplement 1): 1134.

https://doi.org/10.1182/blood-2018-99-119620

Published: 2018

Journal Articles

Defining the Molecular Mechanisms through Which the Macrophage Galactose Lectin (MGL) Receptor Regulates Von Willebrand Factor Clearance

Soracha E Ward, BSc, Jamie M O'Sullivan, Sonia Aguila Martinez, BSc, PhD, Clive Drakeford, BSc, Thomas Anthony Jude McKinnon, BSc, PhD, Alain Chion, BSc, PhD, James S O'Donnell, MD PhD

Blood (2018) 132 (Supplement 1): 980.

https://doi.org/10.1182/blood-2018-99-114775

Published: 2018

Journal Articles

A novel role for the macrophage galactose-type lectin receptor in mediating von Willebrand factor clearance

Soracha E. Ward, Jamie M. O’Sullivan, Clive Drakeford, Sonia Aguila, Christopher N. Jondle, Jyotika Sharma, Padraic G. Fallon, Teresa M. Brophy, Roger J. S. Preston, Paul Smyth, Orla Sheils, Alain Chion, James S. O’Donnell

Blood (2018) 131 (8): 911–916.

https://doi.org/10.1182/blood-2017-06-787853

Published: 2018

Includes: Supplemental data

Journal Articles

A CRISPR-Cas9 Generated Etv6 mutant Mouse Exhibits Decreased Platelet Counts and Functional Platelet Defects

Leila Noetzli, BS, Jesse W Rowley, PhD, Pavel Davizon-Castillo, MD, Greg Kirkpatrick, Katrina J. Ashworth, MS, Sonia Aguila, PhD, Christopher C. Porter, MD, Eric Martin Pietras, PhD, Andrew S. Weyrich, PhD, Jorge Di Paola, MD

Blood (2017) 130 (Supplement 1): 1035.

https://doi.org/10.1182/blood.V130.Suppl_1.1035.1035

Published: 2017

Journal Articles

Aging-Associated Inflammation Due to Elevated Levels of TNF-α Increases Activation of the Integrin αIIbβ3 and the Procoagulant Potential of Platelets

Pavel Davizon-Castillo, MD, Ken L. Jones, PhD, Sonia Aguila, PhD, David Bark, PhD, Katrina J. Ashworth, MS, Kelly Higa, MS, Eric Martin Pietras, PhD, Robert A. Campbell, PhD, Lauren Christine Shih, BA, Natalie Saunders, MD, James DeGregori, Matthew T. Rondina, MD, Jorge Di Paola, MD

Blood (2017) 130 (Supplement 1): 292.

https://doi.org/10.1182/blood.V130.Suppl_1.292.292

Published: 2017

Journal Articles

Novel insights into the clinical phenotype and pathophysiology underlying low VWF levels

Michelle Lavin, Sonia Aguila, Sonja Schneppenheim, Niall Dalton, Kenneth L. Jones, Jamie M. O’Sullivan, Niamh M. O’Connell, Kevin Ryan, Barry White, Mary Byrne, Marie Rafferty, Mairead M. Doyle, Margaret Nolan, Roger J. S. Preston, Ulrich Budde, Paula James, Jorge Di Paola, James S. O’Donnell

Blood (2017) 130 (21): 2344–2353.

https://doi.org/10.1182/blood-2017-05-786699

Published: 2017

Includes: Supplemental data

Journal Articles

Novel Insights into the Clinical Phenotype and Pathophysiology Underlying Low VWF Levels: The Low Von Willebrand Factor in Ireland Cohort (LoVIC) Study

Michelle Lavin, MB FRCPath, Sonia Aguila, PhD, Sonja Schneppenheim, MD, Niall Dalton, BSc, Jamie M O'Sullivan, PhD, Niamh M O'Connell, MB, FRCPath, PhD, Kevin M. Ryan, MB, Mary Byrne, MSc, Margaret Nolan, BSc, Roger Preston, PhD, Ulrich Budde, MD, Paula D. James, MD, Jorge Di Paola, MD, James S O'Donnell, MD PhD

Blood (2016) 128 (22): 873.

https://doi.org/10.1182/blood.V128.22.873.873

Published: 2016

Journal Articles

N-linked glycans within the A2 domain of von Willebrand factor modulate macrophage-mediated clearance

Alain Chion, Jamie M. O’Sullivan, Clive Drakeford, Gudmundur Bergsson, Niall Dalton, Sonia Aguila, Soracha Ward, Padraic G. Fallon, Teresa M. Brophy, Roger J. S. Preston, Lauren Brady, Orla Sheils, Michael Laffan, Thomas A. J. McKinnon, James S. O’Donnell

Blood (2016) 128 (15): 1959–1968.

https://doi.org/10.1182/blood-2016-04-709436

Published: 2016

Includes: Supplemental data

Journal Articles

Amelioration of the severity of heparin-binding antithrombin mutations by posttranslational mosaicism

Irene Martínez-Martínez, José Navarro-Fernández, Alice Østergaard, Ricardo Gutiérrez-Gallego, José Padilla, Nataliya Bohdan, Antonia Miñano, Cristina Pascual, Constantino Martínez, María Eugenia de la Morena-Barrio, Sonia Águila, Shona Pedersen, Søren Risom Kristensen, Vicente Vicente, Javier Corral

Blood (2012) 120 (4): 900–904.

https://doi.org/10.1182/blood-2012-01-406207

Published: 2012

NARROW

The aptamer BT200 blocks interaction of K1405-K1408 in the VWF-A1 domain with macrophage LRP1

Thrombogenesis Mechanisms of High Doses of Ponatinib in Patients with Chronic Myeloid Leukemia (CML) Compared to Tyrosine Kinase Inhibitors

Hydroxyurea Reduces Neutrophil Extracellular Trap Formation in Myeloproliferative Neoplasms

TNF-α–driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging

Increased galactose expression and enhanced clearance in patients with low von Willebrand factor

The Low Von Willebrand Factor in Ireland Cohort Study - Defining Optimal Management for Procedures in Patients with Low VWF (30-50 IU/dL)

TNF-α Driven Inflammation and Mitochondrial Dysfunction Characterize the Platelet Hyperreactivity of Aging and Myeloproliferative Neoplasms (MPN)

Defining the Molecular Mechanisms through Which the Macrophage Galactose Lectin (MGL) Receptor Regulates Von Willebrand Factor Clearance

A novel role for the macrophage galactose-type lectin receptor in mediating von Willebrand factor clearance

A CRISPR-Cas9 Generated Etv6 mutant Mouse Exhibits Decreased Platelet Counts and Functional Platelet Defects

Aging-Associated Inflammation Due to Elevated Levels of TNF-α Increases Activation of the Integrin αIIbβ3 and the Procoagulant Potential of Platelets

Novel insights into the clinical phenotype and pathophysiology underlying low VWF levels

Novel Insights into the Clinical Phenotype and Pathophysiology Underlying Low VWF Levels: The Low Von Willebrand Factor in Ireland Cohort (LoVIC) Study

N-linked glycans within the A2 domain of von Willebrand factor modulate macrophage-mediated clearance

Amelioration of the severity of heparin-binding antithrombin mutations by posttranslational mosaicism

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American Society of Hematology

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American Society of Hematology

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