1-11 of 11
Pavel Davizon-Castillo
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Declining Autophagic Flux Underlies Mitochondrial and Platelet Defects in Aging

Guadalupe Rojas-Sanchez, Jorge Calzada-Martinez, Orlando Esparza, Giovanny Hernandez, Gabriela Dveksler, Ken Jones, Lucas Ting, Catherine Jankowski, Marguerite Kelher, Marilyn Manco-Johnson, Andrew Thorburn, Paola Maycotte, José A López, Pavel Davizon-Castillo
Journal: Blood
Blood (2024) 144 (Supplement 1): 2547.
https://doi.org/10.1182/blood-2024-211413
Published: 2024
Journal Articles

Inflammation Mediated By TNFα Disrupts the Autophagic Flux and Oxidative Phosphorylation of Megakaryocytes and Platelets through the Downregulation of STX17

Guadalupe Rojas-Sanchez, Jorge Calzada-Martinez, Brandon McMahon, Orlando Esparza, Giovanny Hernandez, Dennis L Le, Eric Wartchow, Tzu Phang, Travis Nemkov, Angelo D'Alessandro, Paola Maycotte, Andrew Thorburn, Jose A. Lopez, Pavel Davizon-Castillo
Journal: Blood
Blood (2023) 142 (Supplement 1): 2567.
https://doi.org/10.1182/blood-2023-185498
Published: 2023
Journal Articles

Dysregulated Autophagy in Platelets from JAK2 V617F -Positive Polycythemia Vera and Essential Thrombocythemia Underlies Bioenergetic Failure As a Possible Mechanism for Thrombohemorrhagic Complications

Guadalupe Rojas Sanchez, Orlando Esparza, Brandon McMahon, Giovanny Hernandez, Dennis Le, Travis Nemkov, Angelo D'Alessandro, Andrew Thorburn, José A. López, Pavel Davizon-Castillo
Journal: Blood
Blood (2022) 140 (Supplement 1): 9590–9591.
https://doi.org/10.1182/blood-2022-170014
Published: 2022
Journal Articles

The Therapeutic Modalities of Sickle Cell Disease Reprogram the Platelet Functional-Bioenergetic Profile

Orlando Esparza, Giovanny Hernandez, Rachelle Nuss, David Irwin, Marguerite Kelher, Christopher C. Silliman, Kathryn L. Hassell, Pavel Davizon-Castillo
Journal: Blood
Blood (2021) 138 (Supplement 1): 957.
https://doi.org/10.1182/blood-2021-153908
Published: 2021
Journal Articles

Characterizing the Metabolic Determinants of Thromboinflammation in Myeloproliferative Neoplasms

Orlando Esparza, Brandon McMahon, Giovanny Hernandez, Travis Nemkov, Angelo D'Alessandro, Pavel Davizon-Castillo
Journal: Blood
Blood (2021) 138 (Supplement 1): 4596.
https://doi.org/10.1182/blood-2021-153736
Published: 2021
Journal Articles

TNF-α–driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging

Pavel Davizon-Castillo, Brandon McMahon, Sonia Aguila, David Bark, Katrina Ashworth, Ayed Allawzi, Robert A. Campbell, Emilie Montenont, Travis Nemkov, Angelo D’Alessandro, Nathan Clendenen, Lauren Shih, Natalie A. Sanders, Kelly Higa, Allaura Cox, Zavelia Padilla-Romo, Giovanni Hernandez, Eric Wartchow, George D. Trahan, Eva Nozik-Grayck, Kenneth Jones, Eric M. Pietras, James DeGregori, Matthew T. Rondina, Jorge Di Paola
Journal: Blood
Blood (2019) 134 (9): 727–740.
https://doi.org/10.1182/blood.2019000200
Published: 2019
Includes: Multimedia, Supplemental data
Journal Articles

Single-Cell RNA-Seq Analysis of Native Murine Megakaryocytes from Young and Old Mice Reveals Significant Metabolic and Mitochondrial Differences throughout Megakaryocyte Development

Pavel Davizon-Castillo, MD, Kenneth L. Jones, PhD, George D Trahan, MS, Jorge Di Paola, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1286.
https://doi.org/10.1182/blood-2018-99-120006
Published: 2018
Journal Articles

TNF-α Driven Inflammation and Mitochondrial Dysfunction Characterize the Platelet Hyperreactivity of Aging and Myeloproliferative Neoplasms (MPN)

Pavel Davizon-Castillo, MD, Brandon McMahon, MD, Sonia Aguila, PhD, Kenneth L. Jones, PhD, George D Trahan, MS, Katrina J. Ashworth, MS, David Bark, PhD, Robert A. Campbell, PhD, Kelly Higa, MS, Lauren Christine Shih, BA, Natalie Saunders, MD, James DeGregori, Matthew T. Rondina, MD, Jorge Di Paola, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1134.
https://doi.org/10.1182/blood-2018-99-119620
Published: 2018
Journal Articles

Aging-Associated Inflammation Due to Elevated Levels of TNF-α Increases Activation of the Integrin αIIbβ3 and the Procoagulant Potential of Platelets

Pavel Davizon-Castillo, MD, Ken L. Jones, PhD, Sonia Aguila, PhD, David Bark, PhD, Katrina J. Ashworth, MS, Kelly Higa, MS, Eric Martin Pietras, PhD, Robert A. Campbell, PhD, Lauren Christine Shih, BA, Natalie Saunders, MD, James DeGregori, Matthew T. Rondina, MD, Jorge Di Paola, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 292.
https://doi.org/10.1182/blood.V130.Suppl_1.292.292
Published: 2017
Journal Articles

A CRISPR-Cas9 Generated Etv6 mutant Mouse Exhibits Decreased Platelet Counts and Functional Platelet Defects

Leila Noetzli, BS, Jesse W Rowley, PhD, Pavel Davizon-Castillo, MD, Greg Kirkpatrick, Katrina J. Ashworth, MS, Sonia Aguila, PhD, Christopher C. Porter, MD, Eric Martin Pietras, PhD, Andrew S. Weyrich, PhD, Jorge Di Paola, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1035.
https://doi.org/10.1182/blood.V130.Suppl_1.1035.1035
Published: 2017
Journal Articles

Pro-Inflammatory Cytokines Drive the Development of a Prothrombotic Platelet Phenotype in Inflammation and Aging

Pavel Davizon-Castillo, Katrina Ashworth, MS, Kelly Higa, MS, Giovanny Hernandez, Sumitra Acharya, Robert A. Campbell, PhD, Matthew Rondina, MD, Colm B. Collins, PhD, Anthony Donato, MD, Lisa Lesniewski, James DeGregori, Michael Holer, Nirmal Banda, Jorge Di Paola, MD, Eric Martin Pietras, PhD
Journal: Blood
Blood (2016) 128 (22): 3747.
https://doi.org/10.1182/blood.V128.22.3747.3747
Published: 2016