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Treatment of Relapsed/Refractory MCL

Clinical Trials & Observations
Elisabeth Silkenstedt, Martin Dreyling
Journal: Blood
Blood blood.2023022353.
https://doi.org/10.1182/blood.2023022353
Published: 2024
Journal Articles

Standardized indolent systemic mastocytosis evaluations across a health care system: implications for screening accuracy

Clinical Trials & Observations
Jeremy C. McMurray, Curtis S. Pacheco, Brandon J. Schornack, Xiaoping Sun, Janet A. Brunader, Alexis E. Scott, Juan S. Ariza, Chung-Ting J. Kou, Ryan C. Costantino, Luke M. Pittman, Karla E. Adams, Aubri M. Waters, Eric M. Pryor, Jonathan J. Lyons, Dean D. Metcalfe, Irina Maric, Nathan A. Boggs
Journal: Blood
Blood (2024) 144 (4): 408–419.
https://doi.org/10.1182/blood.2023023347
Published: 2024
Includes: Supplemental data
Journal Articles

Ibrutinib as part of risk-stratified treatment for posttransplant lymphoproliferative disorder: the phase 2 TIDaL trial

Clinical Trials & Observations
Sridhar Chaganti, Shanna Maycock, Graham McIlroy, Aimee Jackson, Rebecca Bishop, Sarah Johnson, Edward Kanfer, Shireen Kassam, Kate Cwynarski, David Wrench, Arvind Arumainathan, Christopher P. Fox, Rod Johnson, Pam McKay, Shankara Paneesha, Clare Rowntree, Constantine Balotis, Graham P. Collins, Andrew Davies, Josh Wright, Sarah Burns, Arian Laurence, Keith Wheatley, Tobias Menne
Journal: Blood
Blood (2024) 144 (4): 392–401.
https://doi.org/10.1182/blood.2024023847
Published: 2024
Includes: Supplemental data
Journal Articles

Does IPSS-R downstaging before transplantation improve the prognosis of patients with myelodysplastic neoplasms?

Clinical Trials & Observations
Christof Scheid, Diderik-Jan Eikema, Michel van Gelder, Urpu Salmenniemi, Johan Maertens, Jakob Passweg, Didier Blaise, Jennifer L. Byrne, Nicolaus Kröger, Katja Sockel, Patrice Chevallier, Jean Henri Bourhis, Jan J. Cornelissen, Henrik Sengeloev, Jürgen Finke, John A. Snowden, Tobias Gedde-Dahl, Jérôme Cornillon, Urs Schanz, Amit Patel, Linda Koster, Liesbeth C. de Wreede, Patrick Hayden, Kavita Raj, Joanna Drozd-Sokolowska, Carmelo Gurnari, Francesco Onida, Donal P. McLornan, Marie Robin, Ibrahim Yakoub-Agha
Journal: Blood
Blood (2024) 144 (4): 445–456.
https://doi.org/10.1182/blood.2023022273
Published: 2024
Includes: Supplemental data
Journal Articles

Increased risk of venous thromboembolism in young and middle-aged individuals with hereditary angioedema: a family study

Clinical Trials & Observations
Linda Sundler Björkman, MirNabi Pirouzifard, Steven P. Grover, Arne Egesten, Jan Sundquist, Kristina Sundquist, Bengt Zöller
Journal: Blood
Blood (2024) 144 (4): 435–444.
https://doi.org/10.1182/blood.2023022996
Published: 2024
Includes: Supplemental data
Journal Articles

EVIDENCE meta-analysis: evaluating minimal residual disease as an intermediate clinical end point for multiple myeloma

Clinical Trials & Observations
Ola Landgren, Thomas J. Prior, Tara Masterson, Christoph Heuck, Orlando F. Bueno, Ajeeta B. Dash, Hermann Einsele, Hartmut Goldschmidt, Stefan Knop, Cong Li, Ulf-Henrik Mellqvist, Ian McFadden, Corina Oprea, Jeremy A. Ross, Mihaela Talpes, Jay R. Hydren, Jennifer M. Ahlstrom, Dickran Kazandjian, Niels Weinhold, Rick Zhang, Maryalice Stetler-Stevenson, Gerald Marti, Sean M. Devlin
Journal: Blood
Blood (2024) 144 (4): 359–367.
https://doi.org/10.1182/blood.2024024371
Published: 2024
Includes: Supplemental data
Journal Articles

Ruxolitinib for pediatric patients with treatment-naïve and steroid-refractory acute graft-versus-host disease (REACH4)

Clinical Trials & Observations
Franco Locatelli, Hyoung Jin Kang, Benedicte Bruno, Virginie Gandemer, Fanny Rialland-Battisti, Maura Faraci, Yoshiyuki Takahashi, Katsuyoshi Koh, Henrique Bittencourt, Grace Cleary, Christine Rosko, Xuechan Li, Annie St. Pierre, Anirudh Cadapa Prahallad, Christina Diaz-de-Heredia
Journal: Blood
Blood blood.2023022565.
https://doi.org/10.1182/blood.2023022565
Published: 2024
Includes: Supplemental data
Journal Articles

JAK2/mTOR Inhibition Fails to Prevent Acute GVHD Despite Reduced Th1/Th17 cells: Final Phase II Trial Results

Clinical Trials & Observations
Joseph A Pidala, Shernan G Holtan, Kelly Walton, Jongphil Kim, Biwei Cao, Hany Elmariah, Asmita Mishra, Nelli Bejanyan, Taiga Nishihori, Farhad Khimani, Lia E Perez, Rawan G Faramand, Marco L. Davila, Shannon McSain, Jordan Pleskow, Jeffrey Baron, Claudio Anasetti, Carlos M Moran Segura, Daniel J Weisdorf, Bruce R Blazar, Jeffrey S. Miller, Veronika Bachanova, Najla El Jurdi, Brian C Betts
Journal: Blood
Blood blood.2024024789.
https://doi.org/10.1182/blood.2024024789
Published: 2024
Includes: Supplemental data
Journal Articles

Diagnostic Guidelines for Familial Hemophagocytic Lymphohistiocytosis Revisited

Clinical Trials & Observations
Jan-Inge Henter, Elena Sieni, Julia Eriksson, Elisabet Bergsten, Ida Hed Myrberg, Scott Canna, Maria Luisa Coniglio, Randy Q Cron, Kate F Kernan, Ashish R. Kumar, Kai Lehmberg, Francesca Minoia, Ahmed Naqvi, Angelo Ravelli, Yongmin Tang, Matteo Bottai, Yenan T Bryceson, AnnaCarin Horne, Michael B. Jordan
Journal: Blood
Blood blood.2024025077.
https://doi.org/10.1182/blood.2024025077
Published: 2024
Includes: Supplemental data
Journal Articles

How I (Diagnose and) Treat Myeloid / Lymphoid Neoplasms with Tyrosine Kinase Gene Fusions

Clinical Trials & Observations
Andreas Reiter, Georgia Metzgeroth, Nicholas C.P. Cross
Journal: Blood
Blood blood.2023022417.
https://doi.org/10.1182/blood.2023022417
Published: 2024
Journal Articles

Acalabrutinib, venetoclax, and obinutuzumab in relapsed/refractory CLL: final efficacy and ctDNA analysis of the CLL2-BAAG trial

Clinical Trials & Observations
Moritz Fürstenau, Adam Giza, Jonathan Weiss, Fanni Kleinert, Sandra Robrecht, Fabian Franzen, Janina Stumpf, Petra Langerbeins, Othman Al-Sawaf, Florian Simon, Anna-Maria Fink, Christof Schneider, Eugen Tausch, Johannes Schetelig, Peter Dreger, Sebastian Böttcher, Kirsten Fischer, Karl-Anton Kreuzer, Matthias Ritgen, Anke Schilhabel, Monika Brüggemann, Stephan Stilgenbauer, Barbara Eichhorst, Michael Hallek, Paula Cramer
Journal: Blood
Blood (2024) 144 (3): 272–282.
https://doi.org/10.1182/blood.2023022730
Published: 2024
Includes: Supplemental data
Journal Articles

Efficacy of CAR T-cell therapy is not impaired by previous bispecific antibody treatment in large B-cell lymphoma

Clinical Trials & Observations
Gilles Crochet, Gloria Iacoboni, Audrey Couturier, Emmanuel Bachy, Josu Iraola-Truchuelo, Thomas Gastinne, Guillaume Cartron, Tom Fradon, Bastien Lesne, Mi Kwon, Romain Gounot, Nuria Martínez-Cibrian, Cristina Castilla-Llorente, Pau Abrisqueta, Manuel Guerreiro, Clémentine Sarkozy, Jose María Aspa-Cilleruelo, Vincent Camus, Stéphanie Guidez, Adrien Chauchet, Eric Deconinck, Krimo Bouabdallah, Francesc Bosch, Pere Barba, Franck Morschhauser, Roch Houot
Journal: Blood
Blood (2024) 144 (3): 334–338.
https://doi.org/10.1182/blood.2024024526
Published: 2024
Includes: Supplemental data
Journal Articles

Obinutuzumab vs rituximab for transplant-eligible patients with mantle cell lymphoma

Clinical Trials & Observations
Clémentine Sarkozy, Mary Callanan, Catherine Thieblemont, Lucie Obéric, Barbara Burroni, Krimo Bouabdallah, Gandhi Damaj, Benoit Tessoulin, Vincent Ribrag, Roch Houot, Franck Morschhauser, Samuel Griolet, Clémentine Joubert, Victoria Cacheux, Vincent Delwail, Violaine Safar, Remy Gressin, Morgane Cheminant, Marie-Hélène Delfau-Larue, Olivier Hermine, Elizabeth Macintyre, Steven Le Gouill
Journal: Blood
Blood (2024) 144 (3): 262–271.
https://doi.org/10.1182/blood.2024023944
Published: 2024
Includes: Supplemental data
Journal Articles

Alternative donor transplantation for severe aplastic anemia: a comparative study of the SAAWP EBMT

CME Clinical Trials & Observations
Juan Montoro, Dirk-Jan Eikema, Joe Tuffnell, Victoria Potter, Krzysztof Kalwak, Constantijn J. M. Halkes, Alexander Kulagin, Matthew Collin, Robert F. Wynn, Stephen Robinson, Emma Nicholson, Henrik Sengeloev, Jennifer Clay, Khalid Halahleh, Elena Skorobogatova, Jaime Sanz, Jakob Passweg, Stephan Mielke, Samppa Ryhänen, Ben Carpenter, Tobias Gedde-Dahl, Eleni Tholouli, Renato Fanin, Philippe Lewalle, Austin Kulasekararaj, Antonio Risitano, Régis Peffault de Latour
Journal: Blood
Blood (2024) 144 (3): 323–333.
https://doi.org/10.1182/blood.2024024173
Published: 2024
Journal Articles

Chronic graft-versus-host disease: Unresolved complication or ancient history?

Clinical Trials & Observations
Joseph A Pidala, Theodore A Gooley, Leo Luznik, Bruce R Blazar
Journal: Blood
Blood blood.2023022735.
https://doi.org/10.1182/blood.2023022735
Published: 2024
Includes: Supplemental data
Journal Articles

Paroxysmal nocturnal hemoglobinuria–related thrombosis in the era of novel therapies: a 2043-patient-year analysis

Clinical Trials & Observations
Carmelo Gurnari, Hussein Awada, Simona Pagliuca, Danai Dima, Fauzia Ullah, Naomi Kawashima, Yasuo Kubota, Ceylan Colak, Valeria Visconte, Bhumika J. Patel, Vikram Dhillon, Naimisha Marneni, Suresh Kumar Balasubramanian, Ashwin Kishtagari, Taha Bat, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2024) 144 (2): 145–155.
https://doi.org/10.1182/blood.2024023988
Published: 2024
Journal Articles

Complete remission with partial hematological recovery as a palliative endpoint for treatment of acute myeloid leukemia

Clinical Trials & Observations
Robert Q. Le, Donna Przepiorka, Haiyan Chen, Yuan Li Shen, E. Dianne Pulte, Kelly Norsworthy, Marc R. Theoret, R. Angelo De Claro
Journal: Blood
Blood (2024) 144 (2): 206–215.
https://doi.org/10.1182/blood.2023023313
Published: 2024
Includes: Supplemental data
Journal Articles

A Phase 1 Clinical Trial of NKTR-255 with CD19-22 CAR-T Cell Therapy for Refractory B-cell Acute Lymphoblastic Leukemia

Clinical Trials & Observations
Hrishikesh Krishna Srinagesh, Clayton Jackson, Parveen Shiraz, Nikeshan Jeyakumar, Mark P Hamilton, Emily Egeler, Sharon Mavroukakis, Adam Kuo, Juancarlos Cancilla, Bita Sahaf, Neha Agarwal, Alyssa M Kanegai, Anne Marijn Kramer, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hitomi Hosoya, Laura J Johnston, Vanessa E Kennedy, Michaela Liedtke, Robert Lowsky, Lekha Mikkilineni, Robert S. Negrin, Andrew R. Rezvani, Surbhi Sidana, Judith A. Shizuru, Melody Smith, Wen-Kai Weng, Steven A Feldman, Matthew J. Frank, Zachary Lee, Mary Tagliaferri, A Mario Q. Marcondes, David B Miklos, Crystal L. Mackall, Lori Muffly
Journal: Blood
Blood blood.2024024952.
https://doi.org/10.1182/blood.2024024952
Published: 2024
Includes: Supplemental data
Journal Articles

Testing for t(3;8) in MYC/BCL6-rearranged large B-cell lymphoma identifies a high-risk subgroup with inferior survival

Clinical Trials & Observations
Bernard D. Maybury, Lisa James, Neil Phillips, Indrani Venkatadasari, Iman Qureshi, James Riley, Georgina Talbot, Shivir Moosai, Hannah Giles, Nicola Chadderton, James Dowds, Pallav Rakesh, Henry Crosland, Aidan Haslam, Sarah Lane, Monica Vega Gonzalez, David Davies, George Cherian, Amir Shenouda, Praveen Kaudlay, Jane Starczynski, Zbigniew Rudzki, Sridhar Chaganti
Journal: Blood
Blood (2024) 144 (1): 113–117.
https://doi.org/10.1182/blood.2024024048
Published: 2024
Includes: Supplemental data
Journal Articles

What clinicians should know about surrogate end points in hematologic malignancies

Clinical Trials & Observations
Côme Bommier, Matthew John Maurer, Jerome Lambert
Journal: Blood
Blood (2024) 144 (1): 11–20.
https://doi.org/10.1182/blood.2023022269
Published: 2024
Includes: Supplemental data