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Journal Articles

Myeloid Neoplasms with t(12;22)(p13;q12) and MN1 Ectopia Are Refractory to Chemotherapy and Can Benefit from Hematopoietic Stem Cell Transplantation

Tong Wang, Xue Chen, MD, Shuang Hui, Jingbo Ni, Ying Yin, Wei Cao, Yan Zhang, Xinyu Wang, Xiaoli Ma, Panxiang Cao, Mingyue Liu, Kylan N. Chen, Fang Wang, MD, Yang Zhang, MD, Daijing Nie, MD, Lili Yuan, Hongxing Liu

Blood (2019) 134 (Supplement_1): 2721.

https://doi.org/10.1182/blood-2019-131610

Published: 2019

Journal Articles

Arsenic Trioxide Abrogate MN1 Mediated RA-Resistance in Acute Promyelocytic Leukemia

Blood (2019) 134 (Supplement_1): 5166.

https://doi.org/10.1182/blood-2019-131595

Published: 2019

Journal Articles

MN1 Expression Is an Indepedent Prognostic Marker in FLT3-Mutated Acute Myeloid Leukemia and Is Involved in the Resistance to FLT3 Inhibitors

Diego A Pereira-Martins, MSc, Juan L Coelho-Silva, BSc, MSc, Isabel Weinhäuser, MSc, Carol Hassibe Thomé, César Alexander Ortiz Rojas, BSc, Luíse A A Simões, BSc, Fabiola Traina, MD PhD, Michael Heuser, MD, Arnold Ganser, MD, Antonio R. Lucena-Araujo, PhD, Eduardo M Rego, MD PhD

Blood (2019) 134 (Supplement_1): 1403.

https://doi.org/10.1182/blood-2019-131542

Published: 2019

Journal Articles

Loss of the selective autophagy receptor p62 impairs murine myeloid leukemia progression and mitophagy

The Duy Nguyen, Shabnam Shaid, Olesya Vakhrusheva, Sebastian E. Koschade, Kevin Klann, Marlyn Thölken, Fatima Baker, Jing Zhang, Thomas Oellerich, Duran Sürün, Anja Derlet, Isabella Haberbosch, Stefan Eimer, Heinz D. Osiewacz, Christian Behrends, Christian Münch, Ivan Dikic, Christian H. Brandts

Blood (2019) 133 (2): 168–179.

https://doi.org/10.1182/blood-2018-02-833475

Published: 2019

Includes: Supplemental data

Journal Articles

Menin Is a Therapeutic Target in MN1 High Leukemia

Clara Libbrecht, MD, Simone Stefanie Riedel, PhD, Jessica Haladyna, BA,MS, Kathrin M. Bernt, MD

Blood (2018) 132 (Supplement 1): 758.

https://doi.org/10.1182/blood-2018-99-115551

Published: 2018

Journal Articles

LSD1 Inhibition Leads to Differentiation in Hoxa9/Meis1- but Not in MN1-Induced Acute Myeloid Leukemia

Jessica Barth, Anna-Maria Scheder, Sebastian Mohr, Johannes Schulz-Fincke, Martin Schmitt, PhD, Alexandra Walter, Milica Tosic, Eric Metzger, Gesine Bug, MD, Michael Lübbert, Manfred Jung, PhD, Hubert Serve, Roland Schüle, PhD, Tobias Berg, MD

Blood (2017) 130 (Supplement 1): 1246.

https://doi.org/10.1182/blood.V130.Suppl_1.1246.1246

Published: 2017

Journal Articles

Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia

Martin Neumann, Michael P Schroeder, PhD, Lorenz Bastian, Jutta Ortiz Tanchez, Cornelia Schlee, Konstandina Isaakidis, Alva Rani James, Lars R. Fransecky, Sebastian Vosberg, Stefan Krebs, PhD, Helmut Blum, PhD, Stefan Schwartz, MD, Thomas Burmeister, Dieter Hoelzer, MD PhD, Philipp A. Greif, MD, Monika Brüggemann, Nicola Goekbuget, MD, Claudia D. Baldus, MD

Blood (2017) 130 (Supplement 1): 2725.

https://doi.org/10.1182/blood.V130.Suppl_1.2725.2725

Published: 2017

Journal Articles

Targeting Meningeoma-1 Driven AML through Epigenetic Modulation of the Cell of Origin

Simone Riedel, PhD, Kathrin M Bernt, MD, Jessica Haladyna, BA, Matthew Bezzant, Brett Stevens, PhD, Daniel A. Pollyea, MD MS, Amit U. Sinha, PhD, Scott A. Armstrong, MD PhD, Qi Wei, PhD, Craig T. Jordan, PhD, Tobias Neff, MD

Blood (2014) 124 (21): 838.

https://doi.org/10.1182/blood.V124.21.838.838

Published: 2014

Journal Articles

DNA Methylation Profiling of Pediatric AML Reveals That Hypomethylation of MN1 Is Characteristic of Inv(16) AML and a Driver of MN1 Overexpression

Nicole S.D. Larmonie, Marry M. van den Heuvel-Eibrink, Askar Obulkasim, Valerie de Haas, Dirk Reinhardt, Martin Zimmermann, Jan Trka, Andre Baruchel, Ronald W. Stam, Rob Pieters, Maarten W.J. Fornerod, C. Michel Zwaan

Blood (2014) 124 (21): 867.

https://doi.org/10.1182/blood.V124.21.867.867

Published: 2014

Journal Articles

Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13

Suzan Imren, Michael Heuser, Maura Gasparetto, Philip A. Beer, Gudmundur L. Norddahl, Ping Xiang, Ling Chen, Tobias Berg, Garrett W. Rhyasen, Patricia Rosten, Gyeongsin Park, Yeonsook Moon, Andrew P. Weng, Connie J. Eaves, R. Keith Humphries

Blood (2014) 124 (24): 3608–3612.

https://doi.org/10.1182/blood-2014-04-564666

Published: 2014

Includes: Supplemental data

Journal Articles

NPM1 Mutated AML Is Associated With Lower Expression Of Poor Prognostic Markers BAALC, ERG and MN1 In Adult Patients With Acute Myeloid Leukaemia

Poonkuzhali Balasubramanian, Ph.D, Ashok kumar Jayavelu, M.Sc, Ajay Abraham, M.Sc, Savitha Varatharajan, M.Sc, Sreeja Karathedath, M.Sc, Senthamizhselvi Anandan, M.Sc, Vivi Srivastava, MD, Aby Abraham, MD, Auro Viswabandya, MD, Alok Srivastava, MD, Vikram Mathews, MD, DM

Blood (2013) 122 (21): 4945.

https://doi.org/10.1182/blood.V122.21.4945.4945

Published: 2013

Journal Articles

Modeling and Targeting MLL-PTD/RUNX1 Related MDS/AML In Mouse

Yue Zhang, MD, Xiaomei Yan, Aili Chen, Goro Sashida, MD, PhD, Zhijian Xiao, MD, Gang Huang, PhD

Blood (2013) 122 (21): 2746.

https://doi.org/10.1182/blood.V122.21.2746.2746

Published: 2013

Journal Articles

The Clinical and Prognostic Influence Of Mutations In The Cohesin Complex In Acute Myeloid Leukemia

Blood (2013) 122 (21): 1314.

https://doi.org/10.1182/blood.V122.21.1314.1314

Published: 2013

Journal Articles

Functional Dissection and Targeting Of Bmi1 Independence Of MN1 Leukemia

Jan-Henrik Mikesch, MD, Maria F Arteaga, PHD, Clemence Virely, PHD, Chi Wai Eric So, PHD

Blood (2013) 122 (21): 474.

https://doi.org/10.1182/blood.V122.21.474.474

Published: 2013

Journal Articles

Adverse Prognostic Impact of GAS6 Expression in De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) (CALGB 8461, 9665, 20202; Alliance)

Susan Whitman, PhD, Jessica Kohlschmidt, PhD, Kati Maharry, MAS, Deedra Nicolet, MS, Sebastian Schwind, MD, Heiko Becker, MD, Klaus H. Metzeler, MD, Krzysztof Mrózek, MD, PhD, Jason H. Mendler, MD, PhD, Ann-Kathrin Eisfeld, MD, Stefano Volinia, PhD, Bayard L. Powell, MD, Thomas H. Carter, MD, PhD, Jonathan E. Kolitz, MD, Richard M. Stone, MD, Il-Kyoo Park, Michael A. Caligiuri, M.D., Guido Marcucci, MD, Clara D. Bloomfield, MD

Blood (2012) 120 (21): 1293.

https://doi.org/10.1182/blood.V120.21.1293.1293

Published: 2012

Journal Articles

BAALC and EVI1 Prognostic Gene Expression in Adult Acute Myeloid Leukemia Using the Amlprofiler Custom Microarray

Erik H van Beers, PhD, Jaap Brand, PhD, Martin H. van Vliet, PhD, Henk E Vietor, MD, PhD, Peter J. M. Valk, PhD, Bob Lowenberg, MD, PhD

Blood (2012) 120 (21): 1420.

https://doi.org/10.1182/blood.V120.21.1420.1420

Published: 2012

Journal Articles

Frequency and Prognostic Impact of NUP98/NSD1 Translocations in Adult AML and MDS Patients

Felicitas Thol, MD, Britta Kölking, Iris H.I.M. Hollink, MD, PhD, Frederik Damm, MD, Marry M. van den Heuvel-Eibrink, C. Michel Zwaan, MD, PhD, Gesine Bug, Oliver G. Ottmann, MD, Katharina Wagner, MD, Michael A Morgan, PhD, Wolf-Karsten Hofmann, Gudrun Göhring, MD, Brigitte Schlegelberger, Jürgen Krauter, Prof. Dr. med., Arnold Ganser, Michael Heuser, MD

Blood (2012) 120 (21): 1402.

https://doi.org/10.1182/blood.V120.21.1402.1402

Published: 2012

Journal Articles

An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model

Blood (2012) 119 (19): 4512–4523.

https://doi.org/10.1182/blood-2010-04-281428

Published: 2012

Includes: Supplemental data

Journal Articles

Over Expression of MN1 Accelerates Leukemia Onset and Confers Resistance to Chemotherapy by Suppression of p53 and Bim

Timothy Pardee, MD, PhD

Blood (2011) 118 (21): 2501.

https://doi.org/10.1182/blood.V118.21.2501.2501

Published: 2011

Journal Articles

ERG, BAALC, and MN1 RNA Levels Are Correlatively Over-Expressed, and Relate to Risk-Defining Prognostic Mutations in Intermediate-Risk Acute Myeloid Leukemia

Fei Yang, Franklin Moore, M.D., Ph.D., Dean Westberry, Miriam Hough, Julie Partain, William H Fleming, MD, PhD, Tibor Kovacsovics, MD, Richard D. Press, MD, PhD

Blood (2011) 118 (21): 1471.

https://doi.org/10.1182/blood.V118.21.1471.1471

Published: 2011

NARROW

Myeloid Neoplasms with t(12;22)(p13;q12) and MN1 Ectopia Are Refractory to Chemotherapy and Can Benefit from Hematopoietic Stem Cell Transplantation

Arsenic Trioxide Abrogate MN1 Mediated RA-Resistance in Acute Promyelocytic Leukemia

MN1 Expression Is an Indepedent Prognostic Marker in FLT3-Mutated Acute Myeloid Leukemia and Is Involved in the Resistance to FLT3 Inhibitors

Loss of the selective autophagy receptor p62 impairs murine myeloid leukemia progression and mitophagy

Menin Is a Therapeutic Target in MN1 High Leukemia

LSD1 Inhibition Leads to Differentiation in Hoxa9/Meis1- but Not in MN1-Induced Acute Myeloid Leukemia

Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia

Targeting Meningeoma-1 Driven AML through Epigenetic Modulation of the Cell of Origin

DNA Methylation Profiling of Pediatric AML Reveals That Hypomethylation of MN1 Is Characteristic of Inv(16) AML and a Driver of MN1 Overexpression

Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13

NPM1 Mutated AML Is Associated With Lower Expression Of Poor Prognostic Markers BAALC, ERG and MN1 In Adult Patients With Acute Myeloid Leukaemia

Modeling and Targeting MLL-PTD/RUNX1 Related MDS/AML In Mouse

The Clinical and Prognostic Influence Of Mutations In The Cohesin Complex In Acute Myeloid Leukemia

Functional Dissection and Targeting Of Bmi1 Independence Of MN1 Leukemia

Adverse Prognostic Impact of GAS6 Expression in De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) (CALGB 8461, 9665, 20202; Alliance)

BAALC and EVI1 Prognostic Gene Expression in Adult Acute Myeloid Leukemia Using the Amlprofiler Custom Microarray

Frequency and Prognostic Impact of NUP98/NSD1 Translocations in Adult AML and MDS Patients

An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model

Over Expression of MN1 Accelerates Leukemia Onset and Confers Resistance to Chemotherapy by Suppression of p53 and Bim

ERG, BAALC, and MN1 RNA Levels Are Correlatively Over-Expressed, and Relate to Risk-Defining Prognostic Mutations in Intermediate-Risk Acute Myeloid Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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