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Paul Sinclair
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Journal Articles

The genomic landscape of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

Qingsong Gao, Sarra L. Ryan, Ilaria Iacobucci, Pankaj S. Ghate, Ruth E. Cranston, Claire Schwab, Abdelrahman H. Elsayed, Lei Shi, Stanley Pounds, Shaohua Lei, Pradyuamna Baviskar, Deqing Pei, Cheng Cheng, Matthew Bashton, Paul Sinclair, David R. Bentley, Mark T. Ross, Zoya Kingsbury, Terena James, Kathryn G. Roberts, Meenakshi Devidas, Yiping Fan, Wenan Chen, Ti-Cheng Chang, Gang Wu, Andrew Carroll, Nyla Heerema, Virginia Valentine, Marcus Valentine, Wenjian Yang, Jun J. Yang, Anthony V. Moorman, Christine J. Harrison, Charles G. Mullighan
Journal: Blood
Blood (2023) 142 (8): 711–723.
https://doi.org/10.1182/blood.2022019094
Published: 2023
Includes: Supplemental data
Journal Articles

Improved Diagnosis of Intrachromosomal Amplification of Chromosome 21 (iAMP21) By Copy Number Profiling

Claire Schwab, Paul Sinclair, PhD, Anthony V. Moorman, PhD, Stephen Hunger, MD, Mignon L. Loh, MD, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Christine Harrison
Journal: Blood
Blood (2016) 128 (22): 1733.
https://doi.org/10.1182/blood.V128.22.1733.1733
Published: 2016
Journal Articles

The ability to cross the blood–cerebrospinal fluid barrier is a generic property of acute lymphoblastic leukemia blasts

Mark T. S. Williams, Yasar M. Yousafzai, Alex Elder, Klaus Rehe, Simon Bomken, Liron Frishman-Levy, Sigal Tavor, Paul Sinclair, Katie Dormon, Dino Masic, Tracey Perry, Victoria J. Weston, Pamela Kearns, Helen Blair, Lisa J. Russell, Olaf Heidenreich, Julie A. E. Irving, Shai Izraeli, Josef Vormoor, Gerard J. Graham, Christina Halsey
Journal: Blood
Blood (2016) 127 (16): 1998–2006.
https://doi.org/10.1182/blood-2015-08-665034
Published: 2016
Includes: Supplemental data
Journal Articles

A Targeted Functional Clone Tracking Assay for the Identification of Tumour Suppressor Genes in BCP- ALL Implicates the Transcription Factors FOXO3 and PRDM1

Paul Sinclair, PhD, Joanna Cheng, Prahlad Raninga, Rebecca Hanna, Shaun Hollern, Amir Enshaei, PhD, Helen Blair, PhD, Sirintra Nakjang, Sarra Ryan, PhD, Jeyanthy Eswaran, PhD, Lars Buechler, Olaf Heidenreich, PhD, Christine Harrison, PhDFRCPath FMedSci
Journal: Blood
Blood (2015) 126 (23): 2449.
https://doi.org/10.1182/blood.V126.23.2449.2449
Published: 2015
Journal Articles

Oncogenomic Screening Strategies to Identify Tumour Suppressor Genes on Chromosome 12 in Acute Myeloid Leukaemia

Jake Clayton, Joanna Cheng, Sarra Ryan, Christine J. Harrison, Paul Sinclair
Journal: Blood
Blood (2014) 124 (21): 898.
https://doi.org/10.1182/blood.V124.21.898.898
Published: 2014
Journal Articles

Identification of Cmtm Family Proteins As Tumor Suppressor and Membrane Regulator in B Cell Precursor Acute Lymphoblastic Leukemia

Jeyanthy Eswaran, PhD, Paul Sinclair, Sirintra Nakjang, PhD, Christine J. Harrison
Journal: Blood
Blood (2014) 124 (21): 3582.
https://doi.org/10.1182/blood.V124.21.3582.3582
Published: 2014
Journal Articles

Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia

Vikki Rand, Helen Parker, Lisa J. Russell, Claire Schwab, Hannah Ensor, Julie Irving, Lisa Jones, Dino Masic, Lynne Minto, Heather Morrison, Sarra Ryan, Hazel Robinson, Paul Sinclair, Anthony V. Moorman, Jonathan C. Strefford, Christine J. Harrison
Journal: Blood
Blood (2011) 117 (25): 6848–6855.
https://doi.org/10.1182/blood-2011-01-329961
Published: 2011
Includes: Supplemental data
Journal Articles

What Is the Initiating Mechanism of iAMP21 in Childhood B Cell Precursor ALL?.

Vikki Rand, Helen Parker, Lisa J Russell, Julie Irving, Lisa Jones, Dino Masic, Lynne Minto, Heather Morrison, Hazel Robinson, Claire Schwab, Paul Sinclair, Anthony V Moorman, Jonathan C Strefford, Christine J Harrison
Journal: Blood
Blood (2009) 114 (22): 581.
https://doi.org/10.1182/blood.V114.22.581.581
Published: 2009