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Matthew J Frigault
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Journal Articles

Rapcabtagene Autoleucel (YTB323) in Patients (Pts) with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL): Phase II Trial Clinical Update

Peter A. Riedell, Mi Kwon, Ian W. Flinn, Michael J. Dickinson, Carlos Solano, Ulrich Jaeger, Javier Briones, Koji Kato, Shaun Fleming, Emmanuel Bachy, Alessandro Rambaldi, Leyla O. Shune, Nirav N. Shah, Didier Blaise, Matthew J. Frigault, Aravind Ramakrishnan, Anne Yang, David Pearson, Aiesha Zia, Eduardo Segura, Aisha Masood, Pere Barba
Journal: Blood
Blood (2024) 144 (Supplement 1): 67.
https://doi.org/10.1182/blood-2024-204264
Published: 2024
Journal Articles

Previous HDM/ASCT Adversely Impacts PFS with BCMA-Directed CAR T-Cell Therapy in Multiple Myeloma

Joshua Gustine, Diana Cirstea, Andrew R. Branagan, Andrew J. Yee, Marcela Maus, Matthew J. Frigault, Noopur Raje
Journal: Blood
Blood (2024) 144 (Supplement 1): 79.
https://doi.org/10.1182/blood-2024-212135
Published: 2024
Journal Articles

A Phase 1/2 Study of a ROR1-Targeting CAR T Cell Therapy (ONCT-808) in Adult Patients with Relapsed/Refractory (R/R) Aggressive B Cell Lymphomas (BCL)

Michael Wang, Patrick Connor Johnson, Salim Yazji, Yisrael Katz, Angela Pietrofeso, James Robinson, Matthew Mei, Matthew J. Frigault, James B. Breitmeyer, Caron A. Jacobson
Journal: Blood
Blood (2024) 144 (Supplement 1): 1743.
https://doi.org/10.1182/blood-2024-200998
Published: 2024
Journal Articles

Phase 1 study of CAR-37 T cells in patients with relapsed or refractory CD37 + lymphoid malignancies

Clinical Trials & Observations
Matthew J. Frigault, Charlotte E. Graham, Trisha R. Berger, Julie Ritchey, Nora K. Horick, Areej El-Jawahri, Irene Scarfò, Andrea Schmidts, Nicholas J. Haradhvala, Marc Wehrli, Won-Ho Lee, Aiyana L. Parker, Hadley R. Wiggin, Amanda Bouffard, Aonkon Dey, Mark B. Leick, Katelin Katsis, Eva L. Elder, Maria A. Dolaher, Daniella T. Cook, Alena A. Chekmasova, Lu Huang, Sarah Nikiforow, Heather Daley, Jerome Ritz, Myriam Armant, Fred Preffer, John F. DiPersio, Valentina Nardi, Yi-Bin Chen, Kathleen M. E. Gallagher, Marcela V. Maus
Journal: Blood
Blood (2024) 144 (11): 1153–1167.
https://doi.org/10.1182/blood.2024024104
Published: 2024
Includes: Supplemental data
Journal Articles

Two years later: CD19 CAR-T going the distance

Clinical Trials & Observations
Eli P. Darnell, Matthew J. Frigault
Journal: Blood
Blood (2024) 143 (5): 379–380.
https://doi.org/10.1182/blood.2023022670
Published: 2024
Journal Articles

Itacitinib for the Prevention of Immune Effector Cell Therapy-Associated Cytokine Release Syndrome: Results from the Phase 2 Incb 39110-211 Placebo-Controlled Randomized Cohort

Matthew J. Frigault, Richard T Maziarz, Jae H. Park, Aleksandr Lazaryan, Nirav N. Shah, Jakub Svoboda, Lazaros J. Lekakis, Ran Reshef, Christine L Phillips, Lea M Burke, Jing Lei, Rodica Morariu-Zamfir, John F. DiPersio
Journal: Blood
Blood (2023) 142 (Supplement 1): 356.
https://doi.org/10.1182/blood-2023-180205
Published: 2023
Journal Articles

Real-World Tisagenlecleucel Outcomes in Richter-Transformed Chronic Lymphocytic Leukemia: A Center for International Blood & Marrow Transplant Research (CIBMTR) Analysis

Mazyar Shadman, Matthew J Frigault, Stephen Ronan Foley, Brian T. Hill, Grant Schofield, Caron Jacobson, Samantha M. Jaglowski, Frederick L. Locke, Daniel J. Landsburg, Ron Ram, Peter A Riedell, Gunjan L. Shah, Leslie L. Popplewell, Ranjan Tiwari, Stephen Lim, Harald Jakob Maier, Marta Majdan, Marcelo Pasquini
Journal: Blood
Blood (2023) 142 (Supplement 1): 3497.
https://doi.org/10.1182/blood-2023-180233
Published: 2023
Journal Articles

Phase 1 Study of CART-Ddbcma for the Treatment of Patients with Relapsed and/or Refractory Multiple Myeloma: Results from at Least 1-Year Follow-up in All Patients

Matthew J. Frigault, Jacalyn Rosenblatt, Binod Dhakal, Noopur S. Raje, Daniella Cook, Mahmoud Gaballa, Estelle Emmanuel-Alejandro, Danielle Nissen, Kamalika C Banerjee, Anand Rotte, Christopher R Heery, David Avigan, Andrzej J Jakubowiak, Michael R. Bishop
Journal: Blood
Blood (2023) 142 (Supplement 1): 1023.
https://doi.org/10.1182/blood-2023-189761
Published: 2023
Journal Articles

Chimeric Antigen Receptor T-Cell (CAR-T) Therapy in Secondary Central Nervous System Large B-Cell Lymphoma (SCNSL): A Multicenter Retrospective Analysis

Gulrayz Ahmed, Aseel Alsouqi, Aniko Szabo, Alexandra E. Rojek, Peter A. Riedell, Farrukh T. Awan, Laura Samples, Mazyar Shadman, Marie Hu, Veronika Bachanova, William Wesson, Nausheen Ahmed, Madiha Iqbal, Mohamed A. Kharfan-Dabaja, Michael Scordo, Patrick Connor Johnson, Yi-Bin Chen, Sawa Ito, Mehdi Hamadani, Matthew J. Frigault
Journal: Blood
Blood (2023) 142 (Supplement 1): 3088.
https://doi.org/10.1182/blood-2023-184345
Published: 2023
Journal Articles

Durable Efficacy and Manageable Safety in Patients Age ≥ 75 Years with Relapsed/Refractory Large B-Cell Lymphoma Treated with Tisagenlecleucel in the Real-World Setting

Daniel J. Landsburg, Michael Heim, Amy Moskop, Stephen Ronan Foley, Brian T. Hill, Grant Schofield, Caron Jacobson, Samantha M. Jaglowski, Frederick L. Locke, Ron Ram, Peter A Riedell, Gunjan L. Shah, Leslie L. Popplewell, Ranjan Tiwari, Stephen Lim, Harald Jakob Maier, Marta Majdan, Marcelo Pasquini, Matthew J Frigault
Journal: Blood
Blood (2023) 142 (Supplement 1): 3496.
https://doi.org/10.1182/blood-2023-179387
Published: 2023
Journal Articles

Trial-in-Progress: A Phase 1/2 Multi-Center Study of Onct-808, a ROR1-Specific CAR T, in Adult Patients with Relapsed/Refractory Aggressive B Cell Lymphoma

Michael L. Wang, Matthew J. Frigault, Salim Yazji, Yisrael Katz, James Robinson, James B. Breitmeyer, Matthew G. Mei, Caron A Jacobson
Journal: Blood
Blood (2023) 142 (Supplement 1): 4857.
https://doi.org/10.1182/blood-2023-180989
Published: 2023
Journal Articles

Use of Cilta-Cel CAR T Cells Following Previous Use of a BCMA-Directed CAR T-Cell Product in Heavily Treated Patients with Relapsed/Refractory Multiple Myeloma: A Single Institution Case Series

Narsis Attar, Diana Cirstea, Andrew R. Branagan, Andrew J. Yee, Matthew J. Frigault, Noopur Raje
Journal: Blood
Blood (2023) 142 (Supplement 1): 6924.
https://doi.org/10.1182/blood-2023-182212
Published: 2023
Journal Articles

Chemotherapy-induced reversal of ciltacabtagene autoleucel–associated movement and neurocognitive toxicity

Clinical Trials & Observations
Charlotte E. Graham, Won-Ho Lee, Hadley R. Wiggin, Valentina M. Supper, Mark B. Leick, Filippo Birocchi, Andrew J. Yee, Angelina Petrichenko, John Everett, Frederic D. Bushman, Hossein Sadrzadeh, Otto Rapalino, Daniel Chiu, Isabel Arrillaga-Romany, Marcela V. Maus, Matthew J. Frigault, Kathleen M. E. Gallagher
Journal: Blood
Blood (2023) 142 (14): 1248–1252.
https://doi.org/10.1182/blood.2023021429
Published: 2023
Includes: Supplemental data
Journal Articles

Neurologic toxicities following adoptive immunotherapy with BCMA-directed CAR T cells

Clinical Trials & Observations
Philipp Karschnia, Kevin C. Miller, Andrew J. Yee, Kai Rejeski, P. Connor Johnson, Noopur Raje, Matthew J. Frigault, Jorg Dietrich
Journal: Blood
Blood (2023) 142 (14): 1243–1248.
https://doi.org/10.1182/blood.2023020571
Published: 2023
Journal Articles

Clonal hematopoiesis of indeterminate potential and risk of death from COVID-19

Peter G. Miller, Geoffrey G. Fell, Brody H. Foy, Allison K. Scherer, Christopher J. Gibson, Adam S. Sperling, Bala B. Burugula, Tetsushi Nakao, Md M. Uddin, Hailey Warren, Lynn Bry, Olga Pozdnyakova, Matthew J. Frigault, Alex G. Bick, Donna Neuberg, John M. Higgins, Michael K. Mansour, Pradeep Natarajan, Annette S. Kim, Jacob O. Kitzman, Benjamin L. Ebert
Journal: Blood
Blood (2022) 140 (18): 1993–1997.
https://doi.org/10.1182/blood.2022018052
Published: 2022
Includes: Supplemental data
Journal Articles

Safety and efficacy of tisagenlecleucel in primary CNS lymphoma: a phase 1/2 clinical trial

Clinical Trials & Observations
Matthew J. Frigault, Jorg Dietrich, Kathleen Gallagher, Mark Roschewski, Justin T. Jordan, Deborah Forst, Scott R. Plotkin, Daniella Cook, Keagan S. Casey, Kevin A. Lindell, Gabriel D. Depinho, Katelin Katsis, Eva Lynn Elder, Mark B. Leick, Bryan Choi, Nora Horick, Frederic Preffer, Meredith Saylor, Steven McAfee, Paul V. O’Donnell, Thomas R. Spitzer, Bimalangshu Dey, Zachariah DeFilipp, Areej El-Jawahri, Tracy T. Batchelor, Marcela V. Maus, Yi-Bin Chen
Journal: Blood
Blood (2022) 139 (15): 2306–2315.
https://doi.org/10.1182/blood.2021014738
Published: 2022
Includes: Supplemental data
Journal Articles

Real-World Efficacy and Safety Outcomes for Patients with Relapsed or Refractory (R/R) Aggressive B-Cell Non-Hodgkin's Lymphoma (aBNHL) Treated with Commercial Tisagenlecleucel: Update from the Center for International Blood and Marrow Transplant Research (CIBMTR) Registry

Daniel J Landsburg, Matthew J. Frigault, Zhen-Huan Hu, Samantha Jaglowski, Frederick L. Locke, Christine Ho, Miguel-Angel Perales, Caron Jacobson, Brian T. Hill, Stephen Ronan Foley, Peter A. Riedell, Ranjan Tiwari, Aisha Masood, Stephen Lim, Marta Majdan, Marcelo C Pasquini, Cameron J. Turtle
Journal: Blood
Blood (2021) 138 (Supplement 1): 429.
https://doi.org/10.1182/blood-2021-146397
Published: 2021
Journal Articles

Rational Chemical and Genetic Modifications Enhance Avidity and Function of CD70-Directed CAR-T-Cells for Myeloid Leukemia

Mark B. Leick, Harrison Silva, Irene Scarfò, Rebecca Larson, Bryan D. Choi, Amanda A Bouffard, Kathleen M.E. Gallagher, Andrea Schmidts, Stefanie R. Bailey, Michael C. Kann, Max Jan, Marc Wehrli, Korneel Grauwet, Matthew J. Frigault, Marcela V. Maus
Journal: Blood
Blood (2021) 138 (Supplement 1): 405.
https://doi.org/10.1182/blood-2021-150596
Published: 2021
Journal Articles

A Phase II Trial of Anakinra for the Prevention of CAR-T Cell Mediated Neurotoxicity

Matthew J. Frigault, Kathleen M.E. Gallagher, Marc Wehrli, Betsy Valles, Keagan Casey, Kevin Lindell, Michael Trailor, Hana Cho, Jami L. Brown, Nora K. Horick, Justin Chou, Rhine R. Shen, Simone Filosto, Adrian Bot, Marcela V. Maus
Journal: Blood
Blood (2021) 138 (Supplement 1): 2814.
https://doi.org/10.1182/blood-2021-146927
Published: 2021
Journal Articles

Tisagenlecleucel Demonstrates Safety, Efficacy and CNS Trafficking in Primary CNS Lymphoma

Matthew J. Frigault, Jorg Dietrich, Kathleen M.E. Gallagher, Irene Scarfò, Mark Roschewski, Justin T Jordan, Deborah A. Forst, Scott R Plotkin, Daniella Cook, Keagan Casey, Katelin Katsis, Kevin Lindell, Michael Trailor, Nora Horick, Steven McAfee, Paul V O'Donnell, Thomas R Spitzer, Bimalangshu R Dey, Zachariah Defilipp, Areej El-Jawahri, Tracy Batchelor, Marcela V. Maus, Yi-Bin Chen
Journal: Blood
Blood (2021) 138 (Supplement 1): 258.
https://doi.org/10.1182/blood-2021-148444
Published: 2021