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Journal Articles

Elevated Clonal Hematopoiesis in Environmentally Exposed Responders Has Distinct Age-Related Patterns and Relies on IL1RAP for Clonal Expansion

Blood (2024) 144 (Supplement 1): 943.

https://doi.org/10.1182/blood-2024-194127

Published: 2024

Journal Articles

DNMT3A R882H Exhibits Greater Inflammatory Potential Than R882C in Primary Hematopoietic Stem and Progenitor Cell Knock-in Model and Population Data

Blood (2023) 142 (Supplement 1): 815.

https://doi.org/10.1182/blood-2023-187244

Published: 2023

Journal Articles

Clonal Hematopoiesis and Inflammation in the Vasculature (CHIVE), a Prospective, Longitudinal Clonal Hematopoiesis Cohort and Biorepository

Blood (2023) 142 (Supplement 1): 5594.

https://doi.org/10.1182/blood-2023-189808

Published: 2023

Journal Articles

A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic data sets

Caitlyn Vlasschaert, Taralynn Mack, J. Brett Heimlich, Abhishek Niroula, Md Mesbah Uddin, Joshua Weinstock, Brian Sharber, Alexander J. Silver, Yaomin Xu, Michael Savona, Christopher Gibson, Matthew B. Lanktree, Michael J. Rauh, Benjamin L. Ebert, Pradeep Natarajan, Siddhartha Jaiswal, Alexander G. Bick

Blood (2023) 141 (18): 2214–2223.

https://doi.org/10.1182/blood.2022018825

Published: 2023

Includes: Supplemental data

Journal Articles

Combined Single-Cell Transcriptomics and Mitochondrial Lineage Tracing Identify IL-6 Signaling Responses in TET2 Clonal Hematopoiesis of Indeterminate Potential

Pawan Bhat, J. Brett Heimlich, Alyssa Parker, Matthew T. Jenkins, Chad R. Potts, Jessica Ulloa, Alexander J. Silver, Donovan J. Brown, Peter Van Galen, Michael R. Savona, Alexander G. Bick, Brent Ferrell

Blood (2022) 140 (Supplement 1): 2891–2892.

https://doi.org/10.1182/blood-2022-167850

Published: 2022

Journal Articles

Primary HSPC-Derived Monocytes with DNMT3A p.R882H Exhibit Activated Myeloid Cell Gene Signatures

Alexander J. Silver, Donovan J. Brown, Maria P. Arrate, Yu Wang, Melissa A. Fischer, Pawan Bhat, J. Brett Heimlich, Alexander G. Bick, P. Brent Ferrell, Yaomin Xu, Michael R. Savona

Blood (2022) 140 (Supplement 1): 2885–2886.

https://doi.org/10.1182/blood-2022-170803

Published: 2022

Journal Articles

Integrating Mosaic Chromosomal Alterations and Single-Nucleotide Variants to Predict Evolution of Clonal Hematopoiesis

Ashwin Kishtagari, MA Wasay Khan, Yajing Li, Cosmin Bejan, Naimisha Marneni, Alexander J. Silver, Kelly von Beck, Travis Spaulding, Shannon Stockton, Christina A. Snider, Kelly Pugh, Andrew Sochacki, Dixon Dorand, Taralynn Mack, Caitlyn Vlasschaert, Brent Ferrell, Yaomin Xu, Michael R. Savona, Alexander G. Bick

Blood (2022) 140 (Supplement 1): 2868–2870.

https://doi.org/10.1182/blood-2022-170957

Published: 2022

Journal Articles

Lactate Utilization Provides a Metabolic Escape to Resist the Antileukemic Activity of BET Inhibition in Acute Myeloid Leukemia

Andrew J. Monteith, Haley E. Ramsey, Dalton Greenwood, Maria P. Arrate, Londa Fuller, Agnieszka E. Gorska, Alexander J. Silver, Donovan J. Brown, Sarah D. Olmstead, Jackson Watke, Matthew J. Stubbs, Jeffrey C. Rathmell, Michael R. Savona

Blood (2022) 140 (Supplement 1): 8709–8710.

https://doi.org/10.1182/blood-2022-164701

Published: 2022

Journal Articles

Children and Young Adults Admitted to a NYC Children's Hospital Had a Similar Rate of Severe COVID-19 Coagulopathy As That Reported in Older Adults

William Beau Mitchell, MD, Jennifer G. Davila, MD, Janine Keenan, RN, Jenai Jackson, Adit Tal, MD, Kerry A Morrone, MD, Ellen J Silver, PhD, Sarah H. O'Brien, MD, Deepa Manwani, MD

Blood (2020) 136 (Supplement 1): 27–28.

https://doi.org/10.1182/blood-2020-138794

Published: 2020

Journal Articles

Venous Thromboembolism Prophylaxis Practices for Patients with Sickle Cell Disease Pre and during the COVID-19 Pandemic

Jennifer G. Davila, MD, W. Beau Mitchell, MD, Kerry A Morrone, MD, Ellen J Silver, PhD, Caterina P Minniti, MD, Henny H. Billett, MD MSc, Payal Desai, MD, Sarah H. O'Brien, MD, Deepa Manwani, MD

Blood (2020) 136 (Supplement 1): 38–39.

https://doi.org/10.1182/blood-2020-137071

Published: 2020

Journal Articles

Loss-of-Function Mutations in Dnmt3a and Tet2 Lead to Accelerated Atherosclerosis and Convergent Macrophage Phenotypes in Mice

Philipp J. Rauch, MD, Alexander J. Silver, BA, Jk Gopakumar, BA, Marie McConkey, PhD, Eti Sinha, BS, Maia Fefer, BS, Eugenia Shvartz, BS, Galina Sukhova, PhD, Peter Libby, MD, Benjamin L. Ebert, MDPhD, Siddhartha Jaiswal, MD PhD

Blood (2018) 132 (Supplement 1): 745.

https://doi.org/10.1182/blood-2018-99-118288

Published: 2018

Journal Articles

PPM1D -truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells

Josephine D. Kahn, Peter G. Miller, Alexander J. Silver, Rob S. Sellar, Shruti Bhatt, Christopher Gibson, Marie McConkey, Dylan Adams, Brenton Mar, Philipp Mertins, Shaunt Fereshetian, Karsten Krug, Haoling Zhu, Anthony Letai, Steven A. Carr, John Doench, Siddhartha Jaiswal, Benjamin L. Ebert

Blood (2018) 132 (11): 1095–1105.

https://doi.org/10.1182/blood-2018-05-850339

Published: 2018

Includes: Supplemental data

Journal Articles

Thrombosis in Myeloproliferative Neoplasms Is Linked to Increased Neutrophil Extracellular Trap (NET) Formation

Ofir Wolach, MD, Rob S Sellar, MD, Kimberly Martinod, PhD, Marie E. McConkey, PhD, Alexander J. Silver, B.S., Ryan Chappell, Richard M. Stone, MD, Martha Wadleigh, MD, David P Steensma, MD, Daniel J. DeAngelo, MD PhD, Ilene Galinsky, MSN, ANPc, Rebekka K. Schneider, MD, Robert F. Padera, MD PhD, Ann Mullally, MD, Denisa D. Wagner, PhD, Benjamin L. Ebert, MD PhD

Blood (2016) 128 (22): 633.

https://doi.org/10.1182/blood.V128.22.633.633

Published: 2016

Journal Articles

PPM1D Truncating Mutations Confer Chemotherapy Resistance in Hematopoietic Stem Cells, Which Is Reversible By PPM1D Inhibition

Josephine Kahn, MD, Alexander J. Silver, B.S., Philipp Mertins, PhD, Steven Carr, PhD, Siddhartha Jaiswal, MD PhD, Benjamin L. Ebert, MD PhD

Blood (2016) 128 (22): 740.

https://doi.org/10.1182/blood.V128.22.740.740

Published: 2016

Journal Articles

Improving Outcomes and Reducing Costs for Cancer Associated Thrombosis Using a Centralized Service: The Cleveland Clinic Experience

Emma Rabinovich, Shiva Shrotriya, Keith R. McCrae, MD, John R. Bartholomew, MD, Bernard J. Silver, MD, Kristine Adams, Alok A. Khorana, MD

Blood (2015) 126 (23): 1122.

https://doi.org/10.1182/blood.V126.23.1122.1122

Published: 2015

Journal Articles

Post Operative Thrombosis Among Patients Testing Indeterminate for Lupus Anticoagulant

Natasha Catherine Edwin, MD, Suchitra Sundaram, MD, Keith R. McCrae, MD, Heesun J. Rogers, MD PhD, Bernard J. Silver, MD

Blood (2014) 124 (21): 4255.

https://doi.org/10.1182/blood.V124.21.4255.4255

Published: 2014

Journal Articles

Risk of Arterial and Venous Thrombosis in Patients with “Indeterminate” Lupus Anticoagulant Testing

Suchitra Sundaram, MD, Natasha Catherine Edwin, MD, Heesun J. Rogers, MD PhD, Bernard J. Silver, MD, Keith R. McCrae, MD

Blood (2014) 124 (21): 4249.

https://doi.org/10.1182/blood.V124.21.4249.4249

Published: 2014

Journal Articles

Somatic Mutations in Splicing Factor 3b, Subunit 1 (SF3B1) Are a Useful Biomarker to Differentiate Between Clonal and Non-Clonal Causes of Sideroblastic Anemia

Valeria Visconte, PhD, Ali Tabarroki, MD, Christopher Gerace, Karam Al-Issa, MD, Eric D. Hsi, MD, Heesun J. Rogers, MD PhD, Mikkael A. Sekeres, MD MS, Bernard J. Silver, MD, Alan E. Lichtin, MD, Sudipto Mukherjee, MD MPH, Ramon V. Tiu, MD

Blood (2014) 124 (21): 5597.

https://doi.org/10.1182/blood.V124.21.5597.5597

Published: 2014

Journal Articles

High-Throughput RNA Interference Screening Identifies Synthetic Lethality Between Oncogenic KRAS Dependency and Suppression of STK33

Claudia Scholl, Stefan Frohling, Ian F. Dunn, David A. Barbie, Anna C. Schinzel, So Young Kim, Serena J. Silver, Lars Bullinger, Peter Sandy, Jesse S. Boehm, David E. Root, Tyler Jacks, William C. Hahn, D. Gary Gilliland

Blood (2008) 112 (11): 3806.

https://doi.org/10.1182/blood.V112.11.3806.3806

Published: 2008

Journal Articles

Characterization of murine bone marrow and spleen-derived stromal cells: analysis of leukocyte marker and growth factor mRNA transcript levels

JM Gimble, C Pietrangeli, A Henley, MA Dorheim, J Silver, A Namen, M Takeichi, C Goridis, PW Kincade

Blood (1989) 74 (1): 303–311.

https://doi.org/10.1182/blood.V74.1.303.303

Published: 1989

NARROW

Elevated Clonal Hematopoiesis in Environmentally Exposed Responders Has Distinct Age-Related Patterns and Relies on IL1RAP for Clonal Expansion

DNMT3A R882H Exhibits Greater Inflammatory Potential Than R882C in Primary Hematopoietic Stem and Progenitor Cell Knock-in Model and Population Data

Clonal Hematopoiesis and Inflammation in the Vasculature (CHIVE), a Prospective, Longitudinal Clonal Hematopoiesis Cohort and Biorepository

A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic data sets

Combined Single-Cell Transcriptomics and Mitochondrial Lineage Tracing Identify IL-6 Signaling Responses in TET2 Clonal Hematopoiesis of Indeterminate Potential

Primary HSPC-Derived Monocytes with DNMT3A p.R882H Exhibit Activated Myeloid Cell Gene Signatures

Integrating Mosaic Chromosomal Alterations and Single-Nucleotide Variants to Predict Evolution of Clonal Hematopoiesis

Lactate Utilization Provides a Metabolic Escape to Resist the Antileukemic Activity of BET Inhibition in Acute Myeloid Leukemia

Children and Young Adults Admitted to a NYC Children's Hospital Had a Similar Rate of Severe COVID-19 Coagulopathy As That Reported in Older Adults

Venous Thromboembolism Prophylaxis Practices for Patients with Sickle Cell Disease Pre and during the COVID-19 Pandemic

Loss-of-Function Mutations in Dnmt3a and Tet2 Lead to Accelerated Atherosclerosis and Convergent Macrophage Phenotypes in Mice

PPM1D -truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells

Thrombosis in Myeloproliferative Neoplasms Is Linked to Increased Neutrophil Extracellular Trap (NET) Formation

PPM1D Truncating Mutations Confer Chemotherapy Resistance in Hematopoietic Stem Cells, Which Is Reversible By PPM1D Inhibition

Improving Outcomes and Reducing Costs for Cancer Associated Thrombosis Using a Centralized Service: The Cleveland Clinic Experience

Post Operative Thrombosis Among Patients Testing Indeterminate for Lupus Anticoagulant

Risk of Arterial and Venous Thrombosis in Patients with “Indeterminate” Lupus Anticoagulant Testing

Somatic Mutations in Splicing Factor 3b, Subunit 1 (SF3B1) Are a Useful Biomarker to Differentiate Between Clonal and Non-Clonal Causes of Sideroblastic Anemia

High-Throughput RNA Interference Screening Identifies Synthetic Lethality Between Oncogenic KRAS Dependency and Suppression of STK33

Characterization of murine bone marrow and spleen-derived stromal cells: analysis of leukocyte marker and growth factor mRNA transcript levels

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American Society of Hematology

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American Society of Hematology

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