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Donovan J Brown
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Journal Articles

DNMT3A R882H Exhibits Greater Inflammatory Potential Than R882C in Primary Hematopoietic Stem and Progenitor Cell Knock-in Model and Population Data

Alexander J Silver, Donovan J Brown, Caitlyn Vlasschaert, Pawan Bhat, Fabio Puddu, Joseph C Van Amburg, Matthew T Villaume, Melissa A Fischer, Maria P Arrate, Yu Wang, Jamie Scotcher, Kristy Stengel, Brianna Nicole Smith, Brian Sharber, Chad R Potts, Mark Consugar, Jonathan Brett Heimlich, Yaomin Xu, P. Brent Ferrell, Jr., Alexander G. Bick, Michael R. Savona
Journal: Blood
Blood (2023) 142 (Supplement 1): 815.
https://doi.org/10.1182/blood-2023-187244
Published: 2023
Journal Articles

Clonal Hematopoiesis and Inflammation in the Vasculature (CHIVE), a Prospective, Longitudinal Clonal Hematopoiesis Cohort and Biorepository

Jonathan Heimlich, Morgan Shannon, Sydney Olson, Alexander J Silver, Ariana Debevec, Zachary Copeland, Caitlyn Vlasschaert, Christina Snider, Ashwin Kishtagari, Donovan J Brown, Travis Spaulding, Manasa R Bhatta, Kelly Pugh, Shannon S Stockton, Jessica Ulloa, Yaomin Xu, Muhamed Baljevic, Sanjay Mohan, Javid J. Moslehi, Eiman Jahangir, Brent Ferrell, Jr., David Slosky, Alexander G. Bick, Michael R. Savona
Journal: Blood
Blood (2023) 142 (Supplement 1): 5594.
https://doi.org/10.1182/blood-2023-189808
Published: 2023
Journal Articles

Lactate Utilization Provides a Metabolic Escape to Resist the Antileukemic Activity of BET Inhibition in Acute Myeloid Leukemia

Andrew J. Monteith, Haley E. Ramsey, Dalton Greenwood, Maria P. Arrate, Londa Fuller, Agnieszka E. Gorska, Alexander J. Silver, Donovan J. Brown, Sarah D. Olmstead, Jackson Watke, Matthew J. Stubbs, Jeffrey C. Rathmell, Michael R. Savona
Journal: Blood
Blood (2022) 140 (Supplement 1): 8709–8710.
https://doi.org/10.1182/blood-2022-164701
Published: 2022
Journal Articles

Combined Single-Cell Transcriptomics and Mitochondrial Lineage Tracing Identify IL-6 Signaling Responses in TET2 Clonal Hematopoiesis of Indeterminate Potential

Pawan Bhat, J. Brett Heimlich, Alyssa Parker, Matthew T. Jenkins, Chad R. Potts, Jessica Ulloa, Alexander J. Silver, Donovan J. Brown, Peter Van Galen, Michael R. Savona, Alexander G. Bick, Brent Ferrell
Journal: Blood
Blood (2022) 140 (Supplement 1): 2891–2892.
https://doi.org/10.1182/blood-2022-167850
Published: 2022
Journal Articles

Primary HSPC-Derived Monocytes with DNMT3A p.R882H Exhibit Activated Myeloid Cell Gene Signatures

Alexander J. Silver, Donovan J. Brown, Maria P. Arrate, Yu Wang, Melissa A. Fischer, Pawan Bhat, J. Brett Heimlich, Alexander G. Bick, P. Brent Ferrell, Yaomin Xu, Michael R. Savona
Journal: Blood
Blood (2022) 140 (Supplement 1): 2885–2886.
https://doi.org/10.1182/blood-2022-170803
Published: 2022