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Pawan Bhat
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Journal Articles

Distinct Transcriptomic Cell States Differentiate Low-Risk MDS from Healthy Marrow

Pawan Bhat, Joseph C. Van Amburg, Thomas J. Gracie, Justin A Cartailler, Chad R Potts, Alexander G. Bick, Robert Welner, P. Brent Ferrell, Jr.
Journal: Blood
Blood (2024) 144 (Supplement 1): 1814.
https://doi.org/10.1182/blood-2024-211672
Published: 2024
Journal Articles

Bone Marrow Spatial Multi-Omics Identifies Reduced Interactions between Hematopoietic Stem Cells and Myeloid Cells in Myelodysplastic Syndrome

Alyssa C. Parker, Joseph C. Van Amburg, Tianzi Zhang, Diane C. Saunders, Thomas J. Gracie, Pawan Bhat, J. Brett Heimlich, John W. Hickey, Emily F. Mason, Ashwin Kishtagari, P. Brent Ferrell, Jr., Alexander G. Bick
Journal: Blood
Blood (2024) 144 (Supplement 1): 4577.
https://doi.org/10.1182/blood-2024-210307
Published: 2024
Journal Articles

DNMT3A R882H Exhibits Greater Inflammatory Potential Than R882C in Primary Hematopoietic Stem and Progenitor Cell Knock-in Model and Population Data

Alexander J Silver, Donovan J Brown, Caitlyn Vlasschaert, Pawan Bhat, Fabio Puddu, Joseph C Van Amburg, Matthew T Villaume, Melissa A Fischer, Maria P Arrate, Yu Wang, Jamie Scotcher, Kristy Stengel, Brianna Nicole Smith, Brian Sharber, Chad R Potts, Mark Consugar, Jonathan Brett Heimlich, Yaomin Xu, P. Brent Ferrell, Jr., Alexander G. Bick, Michael R. Savona
Journal: Blood
Blood (2023) 142 (Supplement 1): 815.
https://doi.org/10.1182/blood-2023-187244
Published: 2023
Journal Articles

Combined Single-Cell Transcriptomics and Mitochondrial Lineage Tracing Identify IL-6 Signaling Responses in TET2 Clonal Hematopoiesis of Indeterminate Potential

Pawan Bhat, J. Brett Heimlich, Alyssa Parker, Matthew T. Jenkins, Chad R. Potts, Jessica Ulloa, Alexander J. Silver, Donovan J. Brown, Peter Van Galen, Michael R. Savona, Alexander G. Bick, Brent Ferrell
Journal: Blood
Blood (2022) 140 (Supplement 1): 2891–2892.
https://doi.org/10.1182/blood-2022-167850
Published: 2022
Journal Articles

Primary HSPC-Derived Monocytes with DNMT3A p.R882H Exhibit Activated Myeloid Cell Gene Signatures

Alexander J. Silver, Donovan J. Brown, Maria P. Arrate, Yu Wang, Melissa A. Fischer, Pawan Bhat, J. Brett Heimlich, Alexander G. Bick, P. Brent Ferrell, Yaomin Xu, Michael R. Savona
Journal: Blood
Blood (2022) 140 (Supplement 1): 2885–2886.
https://doi.org/10.1182/blood-2022-170803
Published: 2022
Journal Articles

Epigenetic Dysregulation Leads to Enhanced IL-1β Signaling and Transcriptional Responses in TET2 Deficient HSPCs

Matthew T. Jenkins, Timothy J Scott, Lindsey N Guerin, Alana M Franceski, Yunli E Chu, Pawan Bhat, Chad R. Potts, Robert S. Welner, Emily Hodges, Brent Ferrell
Journal: Blood
Blood (2022) 140 (Supplement 1): 2883–2884.
https://doi.org/10.1182/blood-2022-169568
Published: 2022