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Melissa A. Fischer
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Journal Articles

Application of a Phenotype-Based Predictive Analytic in a Phase Ib Study of Selinexor and Venetoclax in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Somedeb Ball, Michael T. Byrne, Melissa A Fischer, Farrukh T. Awan, Ben K. Tomlinson, Tess Stopczynski, Lokesh Patil, Christine J. Gu, Chris Leonardi, Katherine J. Walsh, Gregory Dan Ayers, Ashwin Kishtagari, Kateryna Fedorov, Markus D. Lacher, Joseph Wagner, Sanjay R Mohan, Michael R. Savona
Journal: Blood
Blood (2024) 144 (Supplement 1): 6012.
https://doi.org/10.1182/blood-2024-209403
Published: 2024
Journal Articles

Prediction of Volasertib Sensitivity in Acute Myeloid Leukemia Relapsed or Refractory to Venetoclax Plus Azacitidine

Lokesh Patil, Christine J. Gu, Cristina Tognon, Nicola Long, Kara Johnson, Melissa A Fischer, Somedeb Ball, Michael R. Savona, Chris Leonardi, Joseph Wagner, Glenn Michelson, Markus D. Lacher
Journal: Blood
Blood (2024) 144 (Supplement 1): 5818.
https://doi.org/10.1182/blood-2024-206299
Published: 2024
Journal Articles

Preliminary Results from a Phase 1b Dose De-Escalation Stage of Abnl-Marro 001: An International MDS/MPN Working Group Study

Ashwin Kishtagari, Melissa A Fischer, Adam C. Seegmiller, Eric Padron, Thomas Cluzeau, Blanca Xicoy, Sylvain Garciaz, Maria Diez-Campelo, Robert Wallace Corty, Tamara K. Moyo, Theodore P Braun, Jason H. Mendler, Mrinal M. Patnaik, Emily Ferguson Mason, Aaron C. Shaver, Michael Pfeilstoecker, Henry Durivage, Nadjat Medeghri, Barry Anderson, Uwe Platzbecker, Pierre Fenaux, Valeria Santini, Michael R. Savona
Journal: Blood
Blood (2023) 142 (Supplement 1): 1874.
https://doi.org/10.1182/blood-2023-181673
Published: 2023
Journal Articles

DNMT3A R882H Exhibits Greater Inflammatory Potential Than R882C in Primary Hematopoietic Stem and Progenitor Cell Knock-in Model and Population Data

Alexander J Silver, Donovan J Brown, Caitlyn Vlasschaert, Pawan Bhat, Fabio Puddu, Joseph C Van Amburg, Matthew T Villaume, Melissa A Fischer, Maria P Arrate, Yu Wang, Jamie Scotcher, Kristy Stengel, Brianna Nicole Smith, Brian Sharber, Chad R Potts, Mark Consugar, Jonathan Brett Heimlich, Yaomin Xu, P. Brent Ferrell, Jr., Alexander G. Bick, Michael R. Savona
Journal: Blood
Blood (2023) 142 (Supplement 1): 815.
https://doi.org/10.1182/blood-2023-187244
Published: 2023
Journal Articles

Primary HSPC-Derived Monocytes with DNMT3A p.R882H Exhibit Activated Myeloid Cell Gene Signatures

Alexander J. Silver, Donovan J. Brown, Maria P. Arrate, Yu Wang, Melissa A. Fischer, Pawan Bhat, J. Brett Heimlich, Alexander G. Bick, P. Brent Ferrell, Yaomin Xu, Michael R. Savona
Journal: Blood
Blood (2022) 140 (Supplement 1): 2885–2886.
https://doi.org/10.1182/blood-2022-170803
Published: 2022
Journal Articles

Variable Response to BCL2 Inhibition in MDS Is Enhanced across MDS Subtypes with Synergistic Combination of BCL2+MCL1 Inhibition

Melissa A. Fischer, MSc, PhD, Maria Arrate, MSc, Merrida A Childress, PhD, Brianna N Smith, MD MS, Yuanbin Song, MD, Rana Gbyli, MS, Thomas Stricker, MD PhD, Stephanie Halene, MD, Michael R. Savona, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2982.
https://doi.org/10.1182/blood-2019-126578
Published: 2019
Journal Articles

Oral Azacitidine and Cedazuridine Approximate Azacitidine Efficacy in a Murine Model

Haley E. Ramsey, PhDMSc, Maria Arrate, MSc, Londa Fuller, Agnieszka E. Gorska, MSc, Kelli Boyd, DVM, PhD, Melissa A. Fischer, MSc, PhD, Aram Oganesian, PhD, Mohammad Azab, MD, Michael R. Savona, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1376.
https://doi.org/10.1182/blood-2019-125899
Published: 2019
Journal Articles

Combination of Selective Inhibitor of Nuclear Export (SINE) Compounds, Selinexor and KPT-8602, with Venetoclax (ABT-199) Displays Enhanced Activity in Leukemia and Large Cell Lymphoma

Melissa A. Fischer, PhD, Sharon Friedlander, PhD, Leah Hogdal, PhD, Pia Arrate, Hua Chang, PhD, Trinayan Kashyap, MS, Christian Argueta, PhD, Boris Klebanov, MA, MS, William Senapedis, PhD, Erkan Baloglu, PhD MBA, Margaret S. Lee, PhD, Sharon Shacham, PhD MBA, Michael R. Savona, MD
Journal: Blood
Blood (2016) 128 (22): 3949.
https://doi.org/10.1182/blood.V128.22.3949.3949
Published: 2016