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Journal Articles

Dual Targeting of MDM2 and BCL2/Bclxl Demonstrates Potent Synergistic Activity in High-Risk Adult Acute Lymphoblastic Leukemia

Hayden L Bell, Mankaran Singh, Helen J Blair, Olaf Heidenreich, Frederik W. van Delft, Anthony V. Moorman, John Lunec, Julie Irving

Blood (2022) 140 (Supplement 1): 9181–9182.

https://doi.org/10.1182/blood-2022-159573

Published: 2022

Journal Articles

Preclinical Investigation of the p53-MDM2 Antagonist Idasanutlin (RG7388) Demonstrates Significant Activity in High Risk Adult Acute Lymphoblastic Leukemia

Hayden L Bell, Mankaran Singh, MSc, Helen J Blair, PhD, Frederik W. van Delft, MD PhD, Anthony V. Moorman, PhD, John Lunec, PhDMRCR(Hon) FRCPath, Julie Irving, PhD

Blood (2020) 136 (Supplement 1): 38.

https://doi.org/10.1182/blood-2020-139536

Published: 2020

Journal Articles

Disease evolution and outcomes in familial AML with germline CEBPA mutations

Blood (2015) 126 (10): 1214–1223.

https://doi.org/10.1182/blood-2015-05-647172

Published: 2015

Includes: Supplemental data

Journal Articles

The Sub-Clonal Complexity of STIL-TAL1 T-ALL

Caroline L Furness, MD, Marcela B Mansur, PhD, Victoria J Weston, PhD, Sarah Jenkinson, MSc, Frederik W van Delft, MDPhD, Lyndal Kearney, PhD, Ian Titley, PhD, Anthony M Ford, PhD, Rosemary E Gale, Pamela R Kearns, MBChB, PhD FRCPCH, Adolfo A. Ferrando, MD PhD, Christine J. Harrison, Nicola E Potter, PhD, Mel Greaves, FRS

Blood (2014) 124 (21): 3788.

https://doi.org/10.1182/blood.V124.21.3788.3788

Published: 2014

Journal Articles

Cerebral Venous Thrombosis As a Complication of Treatment for Acute Lymphoblastic Leukaemia in Children and Young Adults

Kathryn M Musgrave, MBBS, Frederik W van Delft, MDPhD, Rachel M Clack, BA (hons), Elizabeth A Chalmers, MD, Ajay J. Vora, Tina T Biss, MD

Blood (2014) 124 (21): 585.

https://doi.org/10.1182/blood.V124.21.585.585

Published: 2014

Journal Articles

Clonal Evolution and Sub-Clonal Architecture In Paediatric T-Cell Acute Lymphoblastic Leukaemia (T-ALL)

Caroline L Furness, MD, Marcela B Mansur, PhD, Victoria J Weston, PhD, Frederik W Van Delft, MD PhD, Christine J Harrison, PhD, Lyndal Kearney, PhD, Anthony M Ford, PhD, Pamela R Kearns, MBChB, PhD, FRCPCH, Nicola E Potter, PhD, Jean Soulier, MD, PhD, Adolfo A. Ferrando, MD, PhD, Mel Greaves, PhD, FRS

Blood (2013) 122 (21): 1366.

https://doi.org/10.1182/blood.V122.21.1366.1366

Published: 2013

Journal Articles

Distinctive Genotypes In Infants With T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Marcela B Mansur, PhD, Frederik W Van Delft, MD PhD, Caroline L Furness, MD, Mariana Emerenciano, PhD, Susan M Colman, Emma Butcher, Helena Kempski, Emmanuelle Clappier, Hélène Cave, PhD, Jean Soulier, MD, PhD, Maria S. Pombo-de-Oliveira, MD, PhD, Mel Greaves, PhD, FRS, Anthony M Ford, PhD

Blood (2013) 122 (21): 1377.

https://doi.org/10.1182/blood.V122.21.1377.1377

Published: 2013

Journal Articles

Familial AML With Germline CEBPA Mutations: Extended Clinical Outcomes and Analysis Of Secondary Mutations Using Whole Exome Sequencing

Kiran Tawana, MD, Aline Renneville, Jun Wang, PhD, Panayiotis Georgiades, Xavier Thomas, MD, Valerie Mialou, MD, Aleksander Savic, MD, Frederik W Van Delft, MD PhD, Jennifer G. Treleaven, MD, Sameena Iqbal, Norio Asou, MD, PhD, Naokuni Uike, MD, Konstanze Döhner, MD, Lars Bullinger, MD, PhD, Matthias Stelljes, MD, Csaba Bödör, PhD, James D. Cavenagh, MD, Doris Steinemann, PhD, Tim Ripperger, MD, Brigitte Schlegelberger, MD, PhD, Peter Vandenberghe, MD, PhD, Anne Uyttebroeck, MD, Josep F. Nomdedeu, MD, Henrik Hjorth-Hansen, MD, PhD, Rosemary E Gale, PhD, Cynthia L. Toze, MD, FRCP(C), Michael J. Barnett, BMBS, FRCPC, FRCP, FRCPath, Marianna Zombori, MD, Krisztian Kallay, MD, Jiri Pavlu, MD, Pim Mutsaers, MD, Fred H Menko, MD, Angela Thomas, PhD, FRCPath, FRCP, MB, BS, Christine Wright, MD, Jessica Okosun, MD, Chey Loveday, PhD, Pierre Fenaux, MD, PhD, Hamish Scott, PhD, Claude Preudhomme, Claude Chelala, PhD, Alison Male, MD, Carolyn J. Owen, MD, FRCPC, Matthew Smith, MD, PhD, Jude Fitzgibbon, PhD

Blood (2013) 122 (21): 740.

https://doi.org/10.1182/blood.V122.21.740.740

Published: 2013

Journal Articles

Genetics of Teenage and Young Adult Acute Lymphoblastic T-Cell Leukaemia.

Frederik W Van Delft, MD PhD, Caroline L Furness, MA, MBBChir, MRCPCH, Marcela B Mansur, PhD, Lynne Minto, Julie Irving, Sameena Iqbal, Elda Noronha, Sue Colman, John G Gribben, Maria S Pombo-de-Oliveira, Mel Greaves, MD, PhD

Blood (2012) 120 (21): 2521.

https://doi.org/10.1182/blood.V120.21.2521.2521

Published: 2012

Journal Articles

Epigenetic Changes in CEBPα Gene and Xenotransplantation Model of B Cell Precursor Acute Lymphoblastic Leukemia Switching to Monocytoid Lineage During the Early Phase of the Treatment

Blood (2012) 120 (21): 876.

https://doi.org/10.1182/blood.V120.21.876.876

Published: 2012

Journal Articles

Sub-Clonal Genetic Heterogeneity in BCR-ABL1 Positive Acute Lymphoblastic Leukaemia

Maria-Jose Carnicer, PhD, Frederik W van Delft, MD, PhD, Lyndal Kearney, PhD, Mel Greaves, FRS

Blood (2011) 118 (21): 1348.

https://doi.org/10.1182/blood.V118.21.1348.1348

Published: 2011

Journal Articles

Developmental origins and impact of BCR-ABL1 fusion and IKZF1 deletions in monozygotic twins with Ph + acute lymphoblastic leukemia

Giovanni Cazzaniga, Frederik W. van Delft, Luca Lo Nigro, Anthony M. Ford, Joannah Score, Ilaria Iacobucci, Elena Mirabile, Mary Taj, Susan M. Colman, Andrea Biondi, Mel Greaves

Blood (2011) 118 (20): 5559–5564.

https://doi.org/10.1182/blood-2011-07-366542

Published: 2011

Journal Articles

Modeling the evolution of ETV6-RUNX1 –induced B-cell precursor acute lymphoblastic leukemia in mice

Louise van der Weyden, George Giotopoulos, Alistair G. Rust, Louise S. Matheson, Frederik W. van Delft, Jun Kong, Anne E. Corcoran, Mel F. Greaves, Charles G. Mullighan, Brian J. Huntly, David J. Adams

Blood (2011) 118 (4): 1041–1051.

https://doi.org/10.1182/blood-2011-02-338848

Published: 2011

Includes: Supplemental data

Journal Articles

Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia

Frederik W. van Delft, Sharon Horsley, Sue Colman, Kristina Anderson, Caroline Bateman, Helena Kempski, Jan Zuna, Cornelia Eckert, Vaskar Saha, Lyndal Kearney, Anthony Ford, Mel Greaves

Blood (2011) 117 (23): 6247–6254.

https://doi.org/10.1182/blood-2010-10-314674

Published: 2011

Includes: Supplemental data

Journal Articles

Clonal Origins of 'late' Relapses in ETV6-RUNX1 Acute Lymphoblastic Leukemia..

Frederik W van Delft, Sharon W Horsley, Kristina Anderson, Caroline M Bateman, MBBS, MRCP, Susan Colman, Jan Zuna, MD, PhD, Cornelia Eckert, PhD, MSc, Helena Kempski, Vaskar Saha, PhD, FRCP, FRCPath, Lyndal Kearney, Anthony Ford, Mel Greaves

Blood (2009) 114 (22): 1583.

https://doi.org/10.1182/blood.V114.22.1583.1583

Published: 2009

Journal Articles

Loss of Non-Inherited Maternal MHC and Materno-Fetal Transmission of p190 Type BCR-ABL Leukemia.

Takeshi Isoda, Anthony Ford, Daisuke Tomizawa, Frederik W van Delft, David Gonzalez de Castro, Noriko Mitsuiki, Joannah Score, Tomohiko Taki, Tomohiro Morio, Masatoshi Takagi, Hiroh Saji, Shuki Mizutani, Mel Greaves

Blood (2009) 114 (22): 980.

https://doi.org/10.1182/blood.V114.22.980.980

Published: 2009

Journal Articles

Complexity of Clonal Architecture in Childhood Acute Lymphoblastic Leukaemia

Kristina Anderson, Christoph Lutz, Frederik W. van Delft, Sue Colman, Yanping Guo, Helena Kempski, Anthony . Moorman, V, Tariq Enver, John Swansbury, Lyndal Kearney, Mel Greaves

Blood (2009) 114 (22): LBA-5.

https://doi.org/10.1182/blood.V114.22.LBA-5.LBA-5

Published: 2009

NARROW

Dual Targeting of MDM2 and BCL2/Bclxl Demonstrates Potent Synergistic Activity in High-Risk Adult Acute Lymphoblastic Leukemia

Preclinical Investigation of the p53-MDM2 Antagonist Idasanutlin (RG7388) Demonstrates Significant Activity in High Risk Adult Acute Lymphoblastic Leukemia

Disease evolution and outcomes in familial AML with germline CEBPA mutations

The Sub-Clonal Complexity of STIL-TAL1 T-ALL

Cerebral Venous Thrombosis As a Complication of Treatment for Acute Lymphoblastic Leukaemia in Children and Young Adults

Clonal Evolution and Sub-Clonal Architecture In Paediatric T-Cell Acute Lymphoblastic Leukaemia (T-ALL)

Distinctive Genotypes In Infants With T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Familial AML With Germline CEBPA Mutations: Extended Clinical Outcomes and Analysis Of Secondary Mutations Using Whole Exome Sequencing

Genetics of Teenage and Young Adult Acute Lymphoblastic T-Cell Leukaemia.

Epigenetic Changes in CEBPα Gene and Xenotransplantation Model of B Cell Precursor Acute Lymphoblastic Leukemia Switching to Monocytoid Lineage During the Early Phase of the Treatment

Sub-Clonal Genetic Heterogeneity in BCR-ABL1 Positive Acute Lymphoblastic Leukaemia

Developmental origins and impact of BCR-ABL1 fusion and IKZF1 deletions in monozygotic twins with Ph + acute lymphoblastic leukemia

Modeling the evolution of ETV6-RUNX1 –induced B-cell precursor acute lymphoblastic leukemia in mice

Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia

Clonal Origins of 'late' Relapses in ETV6-RUNX1 Acute Lymphoblastic Leukemia..

Loss of Non-Inherited Maternal MHC and Materno-Fetal Transmission of p190 Type BCR-ABL Leukemia.

Complexity of Clonal Architecture in Childhood Acute Lymphoblastic Leukaemia

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American Society of Hematology

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