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David Gonzalez de Castro
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Journal Articles

Deep-Sequencing Reveals the Molecular Landscape of Splenic Marginal Zone Lymphoma: Biological and Clinical Implications

Matthew JJ Rose-Zerilli, PhD, Marina Parry, Viktor Ljungstrom, Jane Gibson, Jun Wang, Renata Walewska, Helen Parker, PhD, Anton Parker, Zadie Davis, Anne Catherine Gardiner, Neil McIver-Brown, Christina H. Kalpadakis, MD, Aliki Xochelli, Achilles Anagnostopoulos, Claudia Fazi, PhD, David Gonzalez de Castro, PhD, Claire Dearden, MD, Guy Pratt, Richard Rosenquist, MD PhD, Margaret Ashton-Keys, Francesco Forconi, Andrew Collins, PhD, Paolo Ghia, MD PhD, Estella Matutes, MD PhD, Gerassimos A Pangalis, Kostas Stamatopoulos, David G Oscier, MD, Jonathan C Strefford, PhD
Journal: Blood
Blood (2014) 124 (21): 76.
https://doi.org/10.1182/blood.V124.21.76.76
Published: 2014
Journal Articles

CYP2B6*6 is an independent determinant of inferior response to fludarabine plus cyclophosphamide in chronic lymphocytic leukemia

Gillian G. Johnson, Ke Lin, Trevor F. Cox, Melanie Oates, David R. Sibson, Richard Eccles, Bryony Lloyd, Laura-Jayne Gardiner, Daniel F. Carr, Munir Pirmohamed, Jonathan C. Strefford, David G. Oscier, David Gonzalez de Castro, Monica Else, Daniel Catovsky, Andrew R. Pettitt
Journal: Blood
Blood (2013) 122 (26): 4253–4258.
https://doi.org/10.1182/blood-2013-07-516666
Published: 2013
Includes: Supplemental data
Journal Articles

A Rapid and Robust Molecular Diagnostic Approach For Multiple Myeloma – Results From a Large Trial Cohort

Martin F. Kaiser, MD, Dil Begum, BSc, Paula Proszek, MSc, Nasrin Dahir, BSc, David Gonzalez de Castro, PhD, Charlotte Pawlyn, MD, Annamaria Brioli, MD, Suvi Savola, PhD, Walter Gregory, PhD, Roger G. Owen, MD, Graham H. Jackson, MD, Faith E Davies, MD, Brian A Walker, PhD, Gareth J Morgan, MD PhD
Journal: Blood
Blood (2013) 122 (21): 3097.
https://doi.org/10.1182/blood.V122.21.3097.3097
Published: 2013
Journal Articles

The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial

CME Clinical Trials & Observations
David G. Oscier, Matthew J. J. Rose-Zerilli, Nils Winkelmann, David Gonzalez de Castro, Belen Gomez, Jade Forster, Helen Parker, Anton Parker, Anne Gardiner, Andrew Collins, Monica Else, Nicholas C. P. Cross, Daniel Catovsky, Jonathan C. Strefford
Journal: Blood
Blood (2013) 121 (3): 468–475.
https://doi.org/10.1182/blood-2012-05-429282
Published: 2013
Includes: Supplemental data
Journal Articles

Telomere Length Is An Independent Predictor of Outcome After Therapy in CLL: Results From the UKCLL4 Trial,

Anton Parker, Jade Forster, Stacey Reichter, David Gonzalez de Castro, PhD, Daniel Catovsky, MD, David Oscier, MD
Journal: Blood
Blood (2011) 118 (21): 3884.
https://doi.org/10.1182/blood.V118.21.3884.3884
Published: 2011
Journal Articles

Resistance to Selective FLT3 Inhibitors, Driven by FLT3 Ligand and FLT3 Point Mutations, Can Be Overcome with the Dual FLT3-Aurora Kinase Inhibitor CCT241736,

Andrew S. Moore, MBBS, FRACP, Amir Faisal, Vassilios Bavetsias, David Gonzalez de Castro, PhD, Chongbo Sun, Butrus Atrash, Melanie Valenti, Alexis de Haven Brandon, Sian Avery, Andrew DJ Pearson, Paul Workman, Julian Blagg, Florence I Raynaud, Suzanne A Eccles, Spiros Linardopoulos
Journal: Blood
Blood (2011) 118 (21): 3492.
https://doi.org/10.1182/blood.V118.21.3492.3492
Published: 2011
Journal Articles

XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments

Brief Report
Tina Bagratuni, Ping Wu, David Gonzalez de Castro, Emma L. Davenport, Nicholas J. Dickens, Brian A. Walker, Kevin Boyd, David C. Johnson, Walter Gregory, Gareth J. Morgan, Faith E. Davies
Journal: Blood
Blood (2010) 116 (2): 250–253.
https://doi.org/10.1182/blood-2010-01-263236
Published: 2010
Journal Articles

Loss of Non-Inherited Maternal MHC and Materno-Fetal Transmission of p190 Type BCR-ABL Leukemia.

Takeshi Isoda, Anthony Ford, Daisuke Tomizawa, Frederik W van Delft, David Gonzalez de Castro, Noriko Mitsuiki, Joannah Score, Tomohiko Taki, Tomohiro Morio, Masatoshi Takagi, Hiroh Saji, Shuki Mizutani, Mel Greaves
Journal: Blood
Blood (2009) 114 (22): 980.
https://doi.org/10.1182/blood.V114.22.980.980
Published: 2009
Journal Articles

Specific JAK2 mutation ( JAK2 R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia

Brief Report
Lyndal Kearney, David Gonzalez De Castro, Jenny Yeung, Julia Procter, Sharon W. Horsley, Minenori Eguchi-Ishimae, Caroline M. Bateman, Kristina Anderson, Tracy Chaplin, Bryan D. Young, Christine J. Harrison, Helena Kempski, Chi Wai E. So, Anthony M. Ford, Mel Greaves
Journal: Blood
Blood (2009) 113 (3): 646–648.
https://doi.org/10.1182/blood-2008-08-170928
Published: 2009
Includes: Supplemental data
Journal Articles

XBP1 Expression Is An Important Prognostic Factor for Newly Diagnosed Myeloma Patients.

Tina Bagratuni, Ping Wu, David Gonzalez de Castro, Emma L Davenport, Brian A Walker, Matthew W Jenner, David C Johnson, Gareth J. Morgan, Faith E Davies
Journal: Blood
Blood (2008) 112 (11): 1686.
https://doi.org/10.1182/blood.V112.11.1686.1686
Published: 2008
Journal Articles

Acquired Genetic Abnormalities in Acute Lymphoblastic Leukaemia in Patients with Down Syndrome.

Lyndal Kearney, Sharon W. Horsley, Caroline M. Bateman, David Gonzalez De Castro, Bryan D. Young, Tracy Chaplin, Minenori Eguchi, Mel Greaves
Journal: Blood
Blood (2007) 110 (11): 984.
https://doi.org/10.1182/blood.V110.11.984.984
Published: 2007
Journal Articles

The Impact of T h 1/T h 2 Response Variations on Risk of Developing Childhood Leukaemia: A Pilot Study.

Zara M. Josephs, PhD, David Gonzalez de Castro, PhD, David C. Johnson, B.Sc, Astrid Novosel, MD, Arndt Borkhardt, Pr, Katherine Pritchard-Jones, Mel F. Greaves
Journal: Blood
Blood (2005) 106 (11): 849.
https://doi.org/10.1182/blood.V106.11.849.849
Published: 2005
Journal Articles

Molecular Characterization in Hairy Cell Leukemia (HCL): Rearrangement Analysis of Heavy Chain in Immunoglobulin Genes (IgH).

Patricia Martín-Jiménez, Miguel Alcoceba, Maria E. Sarasquete, Ana Balanzategui, David Gonzalez de Castro, Maria C. Chillón, J. A. Queizán, M. Barbón, F. Ortega, M. J. Peñarrubia, D. Borrego, M. Cabezudo, Lorena Blázquez, Adriana Armellini, Carina Fernández, Ramón García-Sanz, Marcos González, J.F. San Miguel
Journal: Blood
Blood (2004) 104 (11): 4798.
https://doi.org/10.1182/blood.V104.11.4798.4798
Published: 2004