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Journal Articles

Mechanistic Insights and Clinical Implications of the Thrombotic Risks of a Highly Prevalent GRK5 Variant Affecting Platelets

Yanki Yarman, Xuefei Zhao, Hyun Sook Ahn, Hannah Thomson, Meghan Roberts, Deborah L. French, Jeffrey Benovic, Timothy J. Stalker, Mortimer Poncz, Peisong Ma

Blood (2024) 144 (Supplement 1): 424.

https://doi.org/10.1182/blood-2024-205760

Published: 2024

Journal Articles

Alterations in GATA1s Chromatin Occupancy Lead to Hyperproliferative, Cytokine-Independent Megakaryopoiesis

Kaoru Takasaki, Kristin Murphy, Eric K. Wafula, Christopher S. Thom, Sara S. Kumar, Ying Ting Sit, Alyssa Gagne, Deborah L. French, Laurie A. Steiner, Stella T. Chou

Blood (2024) 144 (Supplement 1): 1170.

https://doi.org/10.1182/blood-2024-211769

Published: 2024

Journal Articles

Megakaryocyte-induced contraction of plasma clots: cellular mechanisms and structural mechanobiology

Oleg V. Kim, Rustem I. Litvinov, Alyssa L. Gagne, Deborah L. French, Lawrence F. Brass, John W. Weisel

Blood (2024) 143 (6): 548–560.

https://doi.org/10.1182/blood.2023021545

Published: 2024

Includes: Multimedia, Supplemental data

Journal Articles

Mechanobiology of Megakaryocyte-Driven Contraction of Plasma Clots

Oleg Kim, Rustem I. Litvinov, Deborah L. French, Lawrence F. Brass, John W. Weisel

Blood (2023) 142 (Supplement 1): 5392.

https://doi.org/10.1182/blood-2023-191105

Published: 2023

Journal Articles

Single-Cell Transcriptomics Reveal Altered Hematopoietic Mechanisms Driven By T21 and GATA1s

Kaoru Takasaki, Christopher S. Thom, David Smith, Sara S. Kumar, Ying Ting Sit, Alyssa Gagne, Deborah L. French, Stella T. Chou

Blood (2023) 142 (Supplement 1): 2685.

https://doi.org/10.1182/blood-2023-185278

Published: 2023

Journal Articles

LNK/SH2B3 As a Novel Driver in Juvenile Myelomonocytic Leukemia

Astrid Wintering, Anna Hecht, Julia Meyer, Eric Brandon Wong, Deborah L French, Jean Ann Maguire, Chintan Jobaliya, Marta Rojas Vasquez, Sunil J. Desai, Robin Yates Dulman, Eneida R. Nemecek, Farid F Chehab, Mignon L. Loh, Elliot Stieglitz

Blood (2022) 140 (Supplement 1): 6863–6864.

https://doi.org/10.1182/blood-2022-164527

Published: 2022

Journal Articles

Intersection of GATA1 and DYRK1A in Trisomy 21 Leukemogenesis

Ying Ting Sit, Hyun Hyung An, Alyssa Gagne, Deborah L French, Stella T. Chou

Blood (2022) 140 (Supplement 1): 5842–5843.

https://doi.org/10.1182/blood-2022-169399

Published: 2022

Journal Articles

The use of pluripotent stem cells to generate diagnostic tools for transfusion medicine

Hyun Hyung An, Alyssa L. Gagne, Jean Ann Maguire, Giulia Pavani, Osheiza Abdulmalik, Paul Gadue, Deborah L. French, Connie M. Westhoff, Stella T. Chou

Blood (2022) 140 (15): 1723–1734.

https://doi.org/10.1182/blood.2022015883

Published: 2022

Includes: Supplemental data

Journal Articles

In Situ Microscopy Studies of Infused Megakaryocytes: Implications in Thrombopoiesis

Hyunjun Kim, Danuta Jadwiga Jarocha, Ian Johnston, Hyunsook Ahn, Deborah L French, Lubica Rauova, Mortimer Poncz

Blood (2021) 138 (Supplement 1): 4287.

https://doi.org/10.1182/blood-2021-150764

Published: 2021

Journal Articles

Insights into Endogenous Vs Exogenous Cargo-Containing Platelet Alpha-Granules

Sergey Zaytsev, Hyunsook Ahn, Victoria Stepanova, M. Anna Kowalska, Khalil Bdeir, Deborah L French, Rodney M. Camire, Douglas B. Cines, Mortimer Poncz

Blood (2021) 138 (Supplement 1): 1028.

https://doi.org/10.1182/blood-2021-153348

Published: 2021

Journal Articles

Detection of Rh Antibodies in Patient Plasma Using Genome Engineered Induced Pluripotent Stem Cell-Derived Red Cells

Hyun Hyung An, Jean Ann Maguire, Alyssa Gagne, Paul Gadue, Deborah L French, Connie M. Westhoff, Stella T. Chou

Blood (2021) 138 (Supplement 1): 350.

https://doi.org/10.1182/blood-2021-151202

Published: 2021

Journal Articles

RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells

Brian Estevez, Sara Borst, Danuta Jarocha, Varun Sudunagunta, Michael Gonzalez, James Garifallou, Hakon Hakonarson, Peng Gao, Kai Tan, Paul Liu, Sumedha Bagga, Nicholas Holdreith, Wei Tong, Nancy Speck, Deborah L. French, Paul Gadue, Mortimer Poncz

Blood (2021) 137 (19): 2662–2675.

https://doi.org/10.1182/blood.2020006389

Published: 2021

Includes: Supplemental data

Journal Articles

Manipulation of Tropomysin 1 in iPSCs to Enhance in Vitro Blood Cell Production

Christopher Thom, MD PhD, Chintan Jobaliya, Benjamin F Voight, PhD, Stella P Chou, MD, Deborah L French, PhD

Blood (2020) 136 (Supplement 1): 34–35.

https://doi.org/10.1182/blood-2020-142317

Published: 2020

Journal Articles

Utilizing CRISPR-CAS9 Gene Editing Technology in Human Pluripotent Stem Cells to Study Platelet Integrin αIIbβ3 Function

Karen Fong, MD PhD, Chintan Jobaliya, Jean Ann Maguire, PhD, Mortimer Poncz, MD, Deborah L French, PhD, Joel S. Bennett, MD

Blood (2020) 136 (Supplement 1): 3.

https://doi.org/10.1182/blood-2020-134268

Published: 2020

Journal Articles

Tropomyosin 1 Genetically Constrains in Vitro Megakaryopoiesis

Christopher Thom, MD PhD, Chintan Jobaliya, Kimberly Lorenz, PhD, Jean Ann Maguire, PhD, Alyssa Gagne, Paul Gadue, PhD, Deborah L French, PhD, Benjamin F Voight, PhD

Blood (2019) 134 (Supplement_1): 3612.

https://doi.org/10.1182/blood-2019-121538

Published: 2019

Journal Articles

A Novel Approach for Generating Platelet-Delivered FVIII: Role of Transient LRP1 Expression during Megakaryopoiesis

John Tkaczynski, BS, Randolph Lyde, PhD, Hyunsook Ahn, MSc, Francis Ayombil, PhD, Sara Borst, BS, Paul Gadue, PhD, Deborah L French, PhD, Denise Sabatino, PhD, Rodney M. Camire, PhD, Mortimer Poncz, MD

Blood (2019) 134 (Supplement_1): 1102.

https://doi.org/10.1182/blood-2019-124788

Published: 2019

Journal Articles

The Inherited Platelet Disorder of RUNX1 Haploinsufficiency (Familial Platelet Disorder with Associated Myeloid Malignancy (FPDMM)) Has a Marked Deficiency of Megakaryocyte-Biased Hematopoietic Progenitor Cells: Mechanistic Studies and Drug Correction

Brian Estevez, PhD, Sara Borst, BS, Danuta Jadwiga Jarocha, PhD, Varun Sudunagunta, Michael Gonzalez, PhD, Peng Gao, Kai Tan, Deborah L French, PhD, Paul Gadue, PhD, Mortimer Poncz, MD

Blood (2019) 134 (Supplement_1): 220.

https://doi.org/10.1182/blood-2019-124851

Published: 2019

Journal Articles

Customized Induced Pluripotent Stem Cell-Derived Red Cell Reagents

David Posocco, Hyun H An, Jean Ann Maguire, Judith Aeschlimann, Deborah L French, PhD, Paul Gadue, PhD, Connie M. Westhoff, PhD, Stella T Chou, MD

Blood (2017) 130 (Supplement 1): 3.

https://doi.org/10.1182/blood.V130.Suppl_1.3.3

Published: 2017

Journal Articles

Mutation-Specific Signaling Profiles and Therapeutic Vulnerabilities of Induced Pluripotent Stem Cell Models of Juvenile Myelomonocytic Leukemia

Sarah K Tasian, MD, Jessica A Casas, MD MPH, David Posocco, Shilpa Gandre-Babbe, Alyssa Gagne, Ge Liang, Mignon L. Loh, MD, Mitchell J Weiss, MD PhD, Deborah L French, PhD, Stella T Chou, MD

Blood (2017) 130 (Supplement 1): 1678.

https://doi.org/10.1182/blood.V130.Suppl_1.1678.1678

Published: 2017

Journal Articles

Identifying and enriching platelet-producing human stem cell–derived megakaryocytes using factor V uptake

Xiuli Sim, Danuta Jarocha, Vincent Hayes, Hayley A. Hanby, Michael S. Marks, Rodney M. Camire, Deborah L. French, Mortimer Poncz, Paul Gadue

Blood (2017) 130 (2): 192–204.

https://doi.org/10.1182/blood-2017-01-761049

Published: 2017

Includes: Supplemental data

NARROW

Mechanistic Insights and Clinical Implications of the Thrombotic Risks of a Highly Prevalent GRK5 Variant Affecting Platelets

Alterations in GATA1s Chromatin Occupancy Lead to Hyperproliferative, Cytokine-Independent Megakaryopoiesis

Megakaryocyte-induced contraction of plasma clots: cellular mechanisms and structural mechanobiology

Mechanobiology of Megakaryocyte-Driven Contraction of Plasma Clots

Single-Cell Transcriptomics Reveal Altered Hematopoietic Mechanisms Driven By T21 and GATA1s

LNK/SH2B3 As a Novel Driver in Juvenile Myelomonocytic Leukemia

Intersection of GATA1 and DYRK1A in Trisomy 21 Leukemogenesis

The use of pluripotent stem cells to generate diagnostic tools for transfusion medicine

In Situ Microscopy Studies of Infused Megakaryocytes: Implications in Thrombopoiesis

Insights into Endogenous Vs Exogenous Cargo-Containing Platelet Alpha-Granules

Detection of Rh Antibodies in Patient Plasma Using Genome Engineered Induced Pluripotent Stem Cell-Derived Red Cells

RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells

Manipulation of Tropomysin 1 in iPSCs to Enhance in Vitro Blood Cell Production

Utilizing CRISPR-CAS9 Gene Editing Technology in Human Pluripotent Stem Cells to Study Platelet Integrin αIIbβ3 Function

Tropomyosin 1 Genetically Constrains in Vitro Megakaryopoiesis

A Novel Approach for Generating Platelet-Delivered FVIII: Role of Transient LRP1 Expression during Megakaryopoiesis

The Inherited Platelet Disorder of RUNX1 Haploinsufficiency (Familial Platelet Disorder with Associated Myeloid Malignancy (FPDMM)) Has a Marked Deficiency of Megakaryocyte-Biased Hematopoietic Progenitor Cells: Mechanistic Studies and Drug Correction

Customized Induced Pluripotent Stem Cell-Derived Red Cell Reagents

Mutation-Specific Signaling Profiles and Therapeutic Vulnerabilities of Induced Pluripotent Stem Cell Models of Juvenile Myelomonocytic Leukemia

Identifying and enriching platelet-producing human stem cell–derived megakaryocytes using factor V uptake

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American Society of Hematology

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ASH Publications

American Society of Hematology

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