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Issue Archive

Volume 140, Issue 14
October 6 2022
Issue Cover

Table of Contents

Editorial

The demise of Roe v Wade: a hematologist’s perspective
Nancy Berliner
View Articletitled, The demise of <em>Roe v Wade</em>: a hematologist’s perspective

Blood Commentaries

STAT1 and MHCII: guardians of stressed HSCs
Sebastian Kollmann,Veronika Sexl
View Articletitled, STAT1 and MHCII: guardians of stressed HSCs
TLR1/2-stimulated DCs “prime” HSCs via IL-1β
Francisco Caiado,Markus G. Manz
View Articletitled, TLR1/2-stimulated DCs “prime” HSCs via IL-1β
Two’s company but three’s a blast!
Deena Iskander
View Articletitled, Two’s company but three’s a blast!
HSCT for adults with immunodeficiencies
Sridhar Rao,Larisa Broglie
View Articletitled, HSCT for adults with immunodeficiencies

Review Article

ROR1: an orphan becomes apparent
Thomas J. Kipps
View Articletitled, ROR1: an orphan becomes apparent

Hematopoiesis and Stem Cells

STAT1 is essential for HSC function and maintains MHCIIhi stem cells that resist myeloablation and neoplastic expansion
Juan Li,Matthew J. Williams,Hyun Jung Park,Hugo P. Bastos,Xiaonan Wang,Daniel Prins,Nicola K. Wilson,Carys Johnson,Kendig Sham,Michelle Wantoch,Sam Watcham,Sarah J. Kinston,Dean C. Pask,Tina L. Hamilton,Rachel Sneade,Amie K. Waller,Cedric Ghevaert,George S. Vassiliou,Elisa Laurenti,David G. Kent,Berthold Göttgens,Anthony R. Green
View Articletitled, STAT1 is essential for HSC function and maintains MHCII<sup>hi</sup> stem cells that resist myeloablation and neoplastic expansion
Supplemental data
IL-1β expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function
Sidan Li,Juo-Chin Yao,Karolyn A. Oetjen,Joseph R. Krambs,Jun Xia,Jingzhu Zhang,Amy P. Schmidt,Nichole M. Helton,Robert S. Fulton,Sharon E. Heath,Isaiah R. Turnbull,Gabriel Mbalaviele,Timothy J. Ley,Matthew J. Walter,Daniel C. Link
View Articletitled, IL-1β expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function
Supplemental data

Red Cells, Iron, and Erythropoiesis

Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis
Laurel Romano,Katie G. Seu,Julien Papoin,David E. Muench,Diamantis Konstantinidis,André Olsson,Katrina Schlum,Kashish Chetal,Joel Anne Chasis,Narla Mohandas,Betsy J. Barnes,Yi Zheng,H. Leighton Grimes,Nathan Salomonis,Lionel Blanc,Theodosia A. Kalfa
View Articletitled, Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis
Supplemental data

Transplantation

Hematopoietic stem cell transplantation for adolescents and adults with inborn errors of immunity: an EBMT IEWP study
Clinical Trials & Observations
Michael H. Albert,Tiarlan Sirait,Dirk-Jan Eikema,Katerina Bakunina,Claudia Wehr,Felipe Suarez,Maria Laura Fox,Nizar Mahlaoui,Andrew R. Gennery,Arjan C. Lankester,Rita Beier,Maria Ester Bernardo,Venetia Bigley,Caroline A. Lindemans,Siobhan O. Burns,Ben Carpenter,Jaroslaw Dybko,Tayfun Güngör,Fabian Hauck,Su Han Lum,Dmitry Balashov,Roland Meisel,Despina Moshous,Ansgar Schulz,Carsten Speckmann,Mary A. Slatter,Brigitte Strahm,Duygu Uckan-Cetinkaya,Isabelle Meyts,Tanja C. Vallée,Robert Wynn,Bénédicte Neven,Emma C. Morris,for the Inborn Errors Working Party (IEWP) of the European Society for Blood and Marrow Transplantation (EBMT) and the European Society for Immunodeficiencies (ESID)
View Articletitled, Hematopoietic stem cell transplantation for adolescents and adults with inborn errors of immunity: an EBMT IEWP study
Supplemental data

Letter to Blood

Clonal hematopoiesis is not significantly associated with COVID-19 disease severity
Clinical Trials & Observations
Yifan Zhou,Ruba Shalhoub,Stephanie N. Rogers,Shiqin Yu,Muxin Gu,Margarete A. Fabre,Pedro M. Quiros,Tae-Hoon Shin,Arch Diangson,Wenhan Deng,Shubha Anand,Wenhua Lu,Matthew Cullen,Anna L. Godfrey,Jacobus Preller,Jerome Hadjadj,Emmanuelle Jouanguy,Aurélie Cobat,Laurent Abel,Frederic Rieux-Laucat,Benjamin Terrier,Alain Fischer,Lara Novik,Ingelise J. Gordon,Larisa Strom,Martin R. Gaudinski,Andrea Lisco,Irini Sereti,Thomas J. Gniadek,Andrea Biondi,Paolo Bonfanti,Luisa Imberti,Clifton L. Dalgard,Yu Zhang,Kerry Dobbs,Helen C. Su,Luigi D. Notarangelo,Colin O. Wu,Peter J. M. Openshaw,Malcolm G. Semple,Ziad Mallat,Kenneth Baillie,Cynthia E. Dunbar,George S. Vassiliou
View Articletitled, Clonal hematopoiesis is not significantly associated with COVID-19 disease severity
Supplemental data

Blood Work

Blastic plasmacytoid dendritic cell neoplasm in ocular adnexa
Sasan Zandi,Hasan Ghaffar
View Articletitled, Blastic plasmacytoid dendritic cell neoplasm in ocular adnexa
  • Cover Image

    Cover Image

    issue cover

    A hematoxylin and eosin–stained cytospin image of erythroblastic islands from mouse bone marrow highlights the presence of immature granulocytes among the maturing erythroblasts. Both associate closely with the central macrophages, which exhibit transcriptional heterogeneity as revealed by cellular indexing of transcriptome and epitopes sequencing (CITE-seq). See the article by Romano et al on page 1621

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Data mining for second malignancies after CAR-T
Silva A, Almeida ARM, Cachucho A, et al. Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma. Blood. 2021;138(12):1040-1052.
MRD and EFS in pediatric T-lymphoblastic lymphoma
Outcomes of younger patients with mantle-cell lymphoma experiencing late relapse (>24 months): the LATE-POD study
Mutational profile of previously treated chronic lymphocytic leukemia patients progressing on acalabrutinib or ibrutinib

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