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So you know how to treat iron deficiency anemia
Oral iron supplements increase hepcidin and decrease iron absorption from daily or twice-daily doses in iron-depleted young women
Prediction of high- and low-risk multiple myeloma based on gene expression and the International Staging System
Paris-Trousseau thrombocytopenia is phenocopied by the autosomal recessive inheritance of a DNA-binding domain mutation in FLI1
Hemostatic efficacy, safety, and pharmacokinetics of a recombinant von Willebrand factor in severe von Willebrand disease
No evidence of transmission of chronic lymphocytic leukemia through blood transfusion
Outcome of patients with distinct molecular genotypes and cytogenetically normal AML after allogeneic transplantation
Issue Archive
October 22 2015
Table of Contents
BLOOD COMMENTARIES
INSIDE BLOOD COMMENTARY
So you know how to treat iron deficiency anemia
Clinical Trials & Observations
CLINICAL TRIALS AND OBSERVATIONS
Oral iron supplements increase hepcidin and decrease iron absorption from daily or twice-daily doses in iron-depleted young women
Clinical Trials & Observations
Diego Moretti,Jeroen S. Goede,Christophe Zeder,Markus Jiskra,Vaiya Chatzinakou,Harold Tjalsma,Alida Melse-Boonstra,Gary Brittenham,Dorine W. Swinkels,Michael B. Zimmermann
LYMPHOID NEOPLASIA
Prediction of high- and low-risk multiple myeloma based on gene expression and the International Staging System
Clinical Trials & Observations
Rowan Kuiper,Mark van Duin,Martin H. van Vliet,Annemiek Broijl,Bronno van der Holt,Laila el Jarari,Erik H. van Beers,George Mulligan,Hervé Avet-Loiseau,Walter M. Gregory,Gareth Morgan,Hartmut Goldschmidt,Henk M. Lokhorst,Pieter Sonneveld
MYELOID NEOPLASIA
Overexpression and knockout of miR-126 both promote leukemogenesis
Zejuan Li,Ping Chen,Rui Su,Yuanyuan Li,Chao Hu,Yungui Wang,Stephen Arnovitz,Miao He,Sandeep Gurbuxani,Zhixiang Zuo,Abdel G. Elkahloun,Shenglai Li,Hengyou Weng,Hao Huang,Mary Beth Neilly,Shusheng Wang,Eric N. Olson,Richard A. Larson,Michelle M. Le Beau,Jiwang Zhang,Xi Jiang,Minjie Wei,Jie Jin,Paul P. Liu,Jianjun Chen
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
Identification and characterization of VEGF-A–responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans
Sara Massena,Gustaf Christoffersson,Evelina Vågesjö,Cédric Seignez,Karin Gustafsson,François Binet,Carmen Herrera Hidalgo,Antoine Giraud,Jalal Lomei,Simone Weström,Masabumi Shibuya,Lena Claesson-Welsh,Pär Gerwins,Michael Welsh,Johan Kreuger,Mia Phillipson
PLATELETS AND THROMBOPOIESIS
Paris-Trousseau thrombocytopenia is phenocopied by the autosomal recessive inheritance of a DNA-binding domain mutation in FLI1
Brief Report
William S. Stevenson,David J. Rabbolini,Lucinda Beutler,Qiang Chen,Sara Gabrielli,Joel P. Mackay,Timothy A. Brighton,Christopher M. Ward,Marie-Christine Morel-Kopp
RED CELLS, IRON, AND ERYTHROPOIESIS
THROMBOSIS AND HEMOSTASIS
Hemostatic efficacy, safety, and pharmacokinetics of a recombinant von Willebrand factor in severe von Willebrand disease
Clinical Trials & Observations
Joan C. Gill,Giancarlo Castaman,Jerzy Windyga,Peter Kouides,Margaret Ragni,Frank W. G. Leebeek,Ortrun Obermann-Slupetzky,Miranda Chapman,Sandor Fritsch,Borislava G. Pavlova,Isabella Presch,Bruce Ewenstein
Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense
Joni M. Prasad,Oleg V. Gorkun,Harini Raghu,Sherry Thornton,Eric S. Mullins,Joseph S. Palumbo,Ya-Ping Ko,Magnus Höök,Tovo David,Shaun R. Coughlin,Jay L. Degen,Matthew J. Flick
TRANSFUSION MEDICINE
No evidence of transmission of chronic lymphocytic leukemia through blood transfusion
Clinical Trials & Observations
Brief Report
Henrik Hjalgrim,Klaus Rostgaard,Senthil K. Vasan,Henrik Ullum,Christian Erikstrup,Ole B. V. Pedersen,Kaspar R. Nielsen,Kjell-Einar Titlestad,Mads Melbye,Olof Nyrén,Gustaf Edgren
TRANSPLANTATION
Outcome of patients with distinct molecular genotypes and cytogenetically normal AML after allogeneic transplantation
Clinical Trials & Observations
Christoph Schmid,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Myriam Labopin,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Gerard Socié,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Etienne Daguindau,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Liisa Volin,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Anne Huynh,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Jean Henri Bourhis,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Noel Milpied,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Jan Cornelissen,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Patrice Chevallier,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Johan Maertens,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Pavel Jindra,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Didier Blaise,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Stig Lenhoff,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Norbert Ifrah,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Frédéric Baron,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Fabio Ciceri,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Claude Gorin,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Bipin Savani,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Sebastian Giebel,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Emmanuelle Polge,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Jordi Esteve,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Arnon Nagler,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation,Mohamad Mohty,on behalf of the Acute Leukemia Working Party of the European Group of Blood and Bone Marrow Transplantation
BLOOD WORK
ERRATA
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Cover Image
Cover Image
![issue cover]()
Extravascular fibrin polymer is deposited in a wound field following a liver puncture injury. The image is a scanning electron micrograph of a wound field 5 minutes after a 2 mm deep puncture to the right medial hepatic lobe of a wild-type mouse (original magnification ×10 000). Fibrin polymer, with associated entrapped red blood cells, is formed in the damaged zone. The contribution of soluble fibrinogen vs fibrin polymer to hemostasis, thrombosis, wound healing, and disease processes may now be determined utilizing FibAEK mice, which carry normal levels of a mutant fibrinogen that cannot be converted to fibrin polymer by thrombin. See the article by Prasad et al on page 2047.
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