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Issue Archive

Volume 124, Issue 16
October 16 2014
Issue Cover

Table of Contents

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
Life, genes, and death in Ph− MPNs
Clinical Trials & Observations
Richard T. Silver
View Articletitled, Life, genes, and death in Ph<sup>−</sup> MPNs
INSIDE BLOOD COMMENTARY
The hemangioblast revisited
Marella de Bruijn
View Articletitled, The hemangioblast revisited
INSIDE BLOOD COMMENTARY
Inherited macrothrombocytopenias on the rise
Carolina Landolt-Marticorena,Walter H. A. Kahr
View Articletitled, Inherited macrothrombocytopenias on the rise
INSIDE BLOOD COMMENTARY
PMNs deliver first aid to clot
Donna S. Woulfe
View Articletitled, PMNs deliver first aid to clot
INSIDE BLOOD COMMENTARY
HLA-DP1 matching: are we there yet?
Arnon Nagler
View Articletitled, HLA-DP1 matching: are we there yet?

REVIEW ARTICLE

Impact of interferon-γ on hematopoiesis
Alexander M. de Bruin,Carlijn Voermans,Martijn A. Nolte
View Articletitled, Impact of interferon-γ on hematopoiesis
Bedside to bench in juvenile myelomonocytic leukemia: insights into leukemogenesis from a rare pediatric leukemia
Tiffany Y. Chang,Christopher C. Dvorak,Mignon L. Loh
View Articletitled, Bedside to bench in juvenile myelomonocytic leukemia: insights into leukemogenesis from a rare pediatric leukemia

CLINICAL TRIALS AND OBSERVATIONS

Long-term follow-up from a phase 1/2 study of single-agent bortezomib in relapsed systemic AL amyloidosis
Clinical Trials & Observations
Donna E. Reece,Ute Hegenbart,Vaishali Sanchorawala,Giampaolo Merlini,Giovanni Palladini,Joan Bladé,Jean-Paul Fermand,Hani Hassoun,Leonard Heffner,Vishal Kukreti,Robert A. Vescio,Lixia Pei,Christopher Enny,Dixie-Lee Esseltine,Helgi van de Velde,Andrew Cakana,Raymond L. Comenzo
View Articletitled, Long-term follow-up from a phase 1/2 study of single-agent bortezomib in relapsed systemic AL amyloidosis
Supplemental data
Long-term survival and blast transformation in molecularly annotated essential thrombocythemia, polycythemia vera, and myelofibrosis
CME Clinical Trials & Observations
Ayalew Tefferi,Paola Guglielmelli,Dirk R. Larson,Christy Finke,Emnet A. Wassie,Lisa Pieri,Naseema Gangat,Rajmonda Fjerza,Alem A. Belachew,Terra L. Lasho,Rhett P. Ketterling,Curtis A. Hanson,Alessandro Rambaldi,Guido Finazzi,Juergen Thiele,Tiziano Barbui,Animesh Pardanani,Alessandro M. Vannucchi
View Articletitled, Long-term survival and blast transformation in molecularly annotated essential thrombocythemia, polycythemia vera, and myelofibrosis
Supplemental data

GENE THERAPY

Towards gene therapy for EBV-associated posttransplant lymphoma with genetically modified EBV-specific cytotoxic T cells
Ida Ricciardelli,Michael Patrick Blundell,Jennifer Brewin,Adrian Thrasher,Martin Pule,Persis J. Amrolia
View Articletitled, Towards gene therapy for EBV-associated posttransplant lymphoma with genetically modified EBV-specific cytotoxic T cells
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Clonal analysis identifies hemogenic endothelium as the source of the blood-endothelial common lineage in the mouse embryo
Laura Padrón-Barthe,Susana Temiño,Cristina Villa del Campo,Laura Carramolino,Joan Isern,Miguel Torres
View Articletitled, Clonal analysis identifies hemogenic endothelium as the source of the blood-endothelial common lineage in the mouse embryo
Supplemental data

IMMUNOBIOLOGY

Role for early-differentiated natural killer cells in infectious mononucleosis
Tarik Azzi,Anna Lünemann,Anita Murer,Seigo Ueda,Vivien Béziat,Karl-Johan Malmberg,Georg Staubli,Claudine Gysin,Christoph Berger,Christian Münz,Obinna Chijioke,David Nadal
View Articletitled, Role for early-differentiated natural killer cells in infectious mononucleosis
Supplemental data

LYMPHOID NEOPLASIA

Exome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients
Noel F. C. C. de Miranda,Konstantinos Georgiou,Longyun Chen,Chenglin Wu,Zhibo Gao,Apostolos Zaravinos,Susana Lisboa,Gunilla Enblad,Manuel R. Teixeira,Yixin Zeng,Roujun Peng,Qiang Pan-Hammarström
View Articletitled, Exome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients
Supplemental data

PLATELETS AND THROMBOPOIESIS

A new form of macrothrombocytopenia induced by a germ-line mutation in the PRKACG gene
Vladimir T. Manchev,Morgane Hilpert,Eliane Berrou,Ziane Elaib,Achille Aouba,Siham Boukour,Sylvie Souquere,Gerard Pierron,Philippe Rameau,Robert Andrews,François Lanza,Regis Bobe,William Vainchenker,Jean-Philippe Rosa,Marijke Bryckaert,Najet Debili,Remi Favier,Hana Raslova
View Articletitled, A new form of macrothrombocytopenia induced by a germ-line mutation in the <em>PRKACG</em> gene
Supplemental data
Carboxyl-terminal-dependent recruitment of nonmuscle myosin II to megakaryocyte contractile ring during polyploidization
Brief Report
Idinath Badirou,Jiajia Pan,Céline Legrand,Aibing Wang,Larissa Lordier,Siham Boukour,Anita Roy,William Vainchenker,Yunhua Chang
View Articletitled, Carboxyl-terminal-dependent recruitment of nonmuscle myosin II to megakaryocyte contractile ring during polyploidization
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Erythroferrone contributes to recovery from anemia of inflammation
Léon Kautz,Grace Jung,Elizabeta Nemeth,Tomas Ganz
View Articletitled, Erythroferrone contributes to recovery from anemia of inflammation
Supplemental data

THROMBOSIS AND HEMOSTASIS

P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice
Roxane Darbousset,Céline Delierneux,Soraya Mezouar,Alexandre Hego,Christelle Lecut,Isabelle Guillaumat,Markus A. Riederer,Richard J. Evans,Françoise Dignat-George,Laurence Panicot-Dubois,Cécile Oury,Christophe Dubois
View Articletitled, P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice

TRANSPLANTATION

MiR-146a regulates the TRAF6/TNF-axis in donor T cells during GVHD
Natalie Stickel,Gabriele Prinz,Dietmar Pfeifer,Peter Hasselblatt,Annette Schmitt-Graeff,Marie Follo,Robert Thimme,Jürgen Finke,Justus Duyster,Ulrich Salzer,Robert Zeiser
View Articletitled, MiR-146a regulates the TRAF6/TNF-axis in donor T cells during GVHD
Supplemental data
Nonpermissive HLA-DPB1 mismatch increases mortality after myeloablative unrelated allogeneic hematopoietic cell transplantation
Clinical Trials & Observations
Joseph Pidala,Stephanie J. Lee,Kwang Woo Ahn,Stephen Spellman,Hai-Lin Wang,Mahmoud Aljurf,Medhat Askar,Jason Dehn,Marcelo Fernandez Viña,Alois Gratwohl,Vikas Gupta,Rabi Hanna,Mary M. Horowitz,Carolyn K. Hurley,Yoshihiro Inamoto,Adetola A. Kassim,Taiga Nishihori,Carlheinz Mueller,Machteld Oudshoorn,Effie W. Petersdorf,Vinod Prasad,James Robinson,Wael Saber,Kirk R. Schultz,Bronwen Shaw,Jan Storek,William A. Wood,Ann E. Woolfrey,Claudio Anasetti
View Articletitled, Nonpermissive HLA-DPB1 mismatch increases mortality after myeloablative unrelated allogeneic hematopoietic cell transplantation

BLOOD WORK

Lymphoproliferative disorder with Auer rod–like inclusions
Matthew J. Oberley,David T. Yang
View Articletitled, Lymphoproliferative disorder with Auer rod–like inclusions
Sequential development of different acute leukemia types in the same patient
Ioannis Kotsianidis,Constantinos Tsatalas
View Articletitled, Sequential development of different acute leukemia types in the same patient
Childhood myelodysplastic syndrome associated with an acquired Bernard-Soulier–like platelet dysfunction
Marco Frigeni,Monica Galli
View Articletitled, Childhood myelodysplastic syndrome associated with an acquired Bernard-Soulier–like platelet dysfunction

CORRESPONDENCE

The BRAF-V600E mutation in circulating cell-free DNA is a promising biomarker of high-risk adult Langerhans cell histiocytosis
Masayuki Kobayashi,Arinobu Tojo
View Articletitled, The <em>BRAF</em>-V600E mutation in circulating cell-free DNA is a promising biomarker of high-risk adult Langerhans cell histiocytosis
Calreticulin mutation does not modify the IPSET score for predicting the risk of thrombosis among 1150 patients with essential thrombocythemia
Clinical Trials & Observations
Guido Finazzi,Alessandra Carobbio,Paola Guglielmelli,Chiara Cavalloni,Silvia Salmoiraghi,Alessandro M. Vannucchi,Mario Cazzola,Francesco Passamonti,Alessandro Rambaldi,Tiziano Barbui
View Articletitled, Calreticulin mutation does not modify the IPSET score for predicting the risk of thrombosis among 1150 patients with essential thrombocythemia
New nucleotide polymerase inhibitors to rapidly permit hematopoietic stem cell donation from a positive HCV-RNA donor
Clinical Trials & Observations
Florence Beckerich,Christophe Hézode,Christine Robin,Jean-Louis Beaumont,Eric Gautier,Sébastien Maury,Catherine Cordonnier
View Articletitled, New nucleotide polymerase inhibitors to rapidly permit hematopoietic stem cell donation from a positive HCV-RNA donor

CONTINUING MEDICAL EDUCATION (CME) QUESTIONS

Mutation-specific survival in MPN
CME
View Articletitled, Mutation-specific survival in MPN
All Issues

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