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Residual DNA methylation at remission is prognostic in adult Philadelphia chromosome–negative acute lymphocytic leukemia
Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma
Issue Archive
February 26 2009
In this Issue
Table of Contents
INSIDE BLOOD
PHAGOCYTES & GRANULOCYTES
Long-lived life: a detriment
In this issue of Blood, Fernandez-Boyanapalli and colleagues report that macrophages isolated from X-linked CGD mice exhibit decreased recognition and removal of apoptotic inflammatory cells secondary to attenuated endogenous IL-4 production.
PLATELETS & THROMBOPOIESIS
Orai1: a channel to safer antithrombotic therapy
In this issue of Blood, Braun and colleagues identify Orai1 as the major component of the store-operated Ca2+ entry channel in platelets. Their findings have significance for the development of safer antithrombotic drugs.
THROMBOSIS & HEMOSTASIS
Supercharged blood coagulation
In this issue of Blood, Undas and colleagues show that patients with AMI are able to mount an enhanced blood clotting response in the peripheral microvasculature.
REVIEW ARTICLES
Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet
Miguel A. Sanz,David Grimwade,Martin S. Tallman,Bob Lowenberg,Pierre Fenaux,Elihu H. Estey,Tomoki Naoe,Eva Lengfelder,Thomas Büchner,Hartmut Döhner,Alan K. Burnett,Francesco Lo-Coco
CLINICAL TRIALS AND OBSERVATIONS
Residual DNA methylation at remission is prognostic in adult Philadelphia chromosome–negative acute lymphocytic leukemia
Clinical Trials & Observations
Hui Yang,Tapan Kadia,Lianchun Xiao,Carlos E. Bueso-Ramos,Koyu Hoshino,Deborah Ann Thomas,Susan O'Brien,Elias Jabbour,Sherry Pierce,Gary L. Rosner,Hagop M. Kantarjian,Guillermo Garcia-Manero
Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma
Clinical Trials & Observations
Joanne S. Colt,Nathaniel Rothman,Richard K. Severson,Patricia Hartge,James R. Cerhan,Nilanjan Chatterjee,Wendy Cozen,Lindsay M. Morton,Anneclaire J. De Roos,Scott Davis,Stephen Chanock,Sophia S. Wang
GENE THERAPY
Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1
Robert C. Carlisle,Ying Di,Anna M. Cerny,Andreas F.-P. Sonnen,Robert B. Sim,Nicola K. Green,Vladimir Subr,Karel Ulbrich,Robert J. C. Gilbert,Kerry D. Fisher,Robert W. Finberg,Leonard W. Seymour
HEMATOPOIESIS AND STEM CELLS
IMMUNOBIOLOGY
Blood diffusion and Th1-suppressive effects of galectin-9–containing exosomes released by Epstein-Barr virus–infected nasopharyngeal carcinoma cells
Jihène Klibi,Toshiro Niki,Alexander Riedel,Catherine Pioche-Durieu,Sylvie Souquere,Eric Rubinstein,Sylvestre Le Moulec,Joël Guigay,Mitsuomi Hirashima,Fethi Guemira,Dinesh Adhikary,Josef Mautner,Pierre Busson
Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes
Ulrich Salzer,Chiara Bacchelli,Sylvie Buckridge,Qiang Pan-Hammarström,Stephanie Jennings,Vassilis Lougaris,Astrid Bergbreiter,Tina Hagena,Jennifer Birmelin,Alessandro Plebani,A. David B. Webster,Hans-Hartmut Peter,Daniel Suez,Helen Chapel,Andrew McLean-Tooke,Gavin P. Spickett,Stephanie Anover-Sombke,Hans D. Ochs,Simon Urschel,Bernd H. Belohradsky,Sanja Ugrinovic,Dinakantha S. Kumararatne,Tatiana C. Lawrence,Are M. Holm,Jose L. Franco,Ilka Schulze,Pascal Schneider,E. Michael Gertz,Alejandro A. Schäffer,Lennart Hammarström,Adrian J. Thrasher,H. Bobby Gaspar,Bodo Grimbacher
LYMPHOID NEOPLASIA
Defining the target specificity of ABT-737 and synergistic antitumor activities in combination with histone deacetylase inhibitors
Kate F. Whitecross,Amber E. Alsop,Leonie A. Cluse,Adrian Wiegmans,Kellie-Marie Banks,Claudia Coomans,Melissa J. Peart,Andrea Newbold,Ralph K. Lindemann,Ricky W. Johnstone
Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis
Haiming Chen,Richard A. Campbell,Yunchao Chang,Mingjie Li,Cathy S. Wang,Jennifer Li,Eric Sanchez,Michael Share,Jeffrey Steinberg,Ariana Berenson,Dror Shalitin,Zhaohui Zeng,Dorina Gui,Pablo Perez-Pinera,Ronald J. Berenson,Jonathan Said,Benjamin Bonavida,Thomas F. Deuel,James R. Berenson
Modification of the cysteine residues in IκBα kinase and NF-κB (p65) by xanthohumol leads to suppression of NF-κB–regulated gene products and potentiation of apoptosis in leukemia cells
Kuzhuvelil B. Harikumar,Ajaikumar B. Kunnumakkara,Kwang S. Ahn,Preetha Anand,Sunil Krishnan,Sushovan Guha,Bharat B. Aggarwal
MYELOID NEOPLASIA
Clonal analysis of deletions on chromosome 20q and JAK2-V617F in MPD suggests that del20q acts independently and is not one of the predisposing mutations for JAK2-V617F
Franz X. Schaub,Roland Jäger,Renate Looser,Hui Hao-Shen,Sylvie Hermouet,François Girodon,Andre Tichelli,Heinz Gisslinger,Robert Kralovics,Radek C. Skoda
High-affinity neurotrophin receptors and ligands promote leukemogenesis
Zhixiong Li,Gernot Beutel,Mathias Rhein,Johann Meyer,Christian Koenecke,Thomas Neumann,Min Yang,Jürgen Krauter,Nils von Neuhoff,Michael Heuser,Helmut Diedrich,Gudrun Göhring,Ludwig Wilkens,Brigitte Schlegelberger,Arnold Ganser,Christopher Baum
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
PLATELETS AND THROMBOPOIESIS
THROMBOSIS AND HEMOSTASIS
TRANSFUSION MEDICINE
Plasma from stored packed red blood cells and MHC class I antibodies causes acute lung injury in a 2-event in vivo rat model
Marguerite R. Kelher,Tomhiko Masuno,Ernest E. Moore,Sagar Damle,Xianzhong Meng,Yong Song,Xiayuan Liang,Jerry Niedzinski,Steven S. Geier,Samina Y. Khan,Fabia Gamboni-Robertson,Christopher C. Silliman
TRANSPLANTATION
Hematopoietic stem cell transplantation for core binding factor acute myeloid leukemia: t(8;21) and inv(16) represent different clinical outcomes
Yachiyo Kuwatsuka,Koichi Miyamura,Ritsuro Suzuki,Masaharu Kasai,Atsuo Maruta,Hiroyasu Ogawa,Ryuji Tanosaki,Satoshi Takahashi,Kyuhei Koda,Kazuhiro Yago,Yoshiko Atsuta,Takashi Yoshida,Hisashi Sakamaki,Yoshihisa Kodera
VASCULAR BIOLOGY
CORRESPONDENCE
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Cover Image
Cover Image
![issue cover]()
GFP-positive monocytes (green) injected into SCID mice in combination with human myeloma cells contribute to Tie-2 positive (red) tumor endothelium as evidenced by dual fluorescence (yellow) in new vessels found in tumor sections. See the article by Chen et al on page 1992.
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