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Journal Articles

CD47-blockade induces programmed necroptosis and complements the effects of BCL-2 inhibition in lymphoid malignancies

Free
Stephen Chong, Rebecca Valentin, Jing Wang, Fen Zhu, Praful Gokhale, Benjamin Eschle, Filip Garbicz, Tomasz Sewastianik, Johany Penailillo, Jeremy Zhang, Liam Hackett, Mary Collins, Timothy Lehmberg, Marisa Peluso, Ammar Adam, Li Zhang, Caroline Armet, Matthew Rausch, Benjamin Lee, Pamela Holland, Vito Palombella, Alison Paterson, Li Ren Kong, Elisa Ten Hacken, Jennifer Guerriero, Charles Herbaux, Catherine Wu, Shazib Pervaiz, Carsten Niemann, Ruben Carrasco, Matthew S Davids
Journal: Blood
Blood (2025) 146 (Supplement 1): 1525.
https://doi.org/10.1182/blood-2025-1525
Published: 2025
Journal Articles

Effects of the Btk Inhibitor Ibrutinib on Monocyte Responses to Antibodies

Free
Li Ren, Amanda Campbell, Shalini Gautam, Huiqing Fang, Kavin Fatehchand, Andrew Stiff, Payal Mehta, Xiaokui Mo, PhD MAS, Xuexun Fang, John C. Byrd, MD, William Carson, Jonathan P. Butchar, PhD, Susheela Tridandapani, PhD
Journal: Blood
Blood (2015) 126 (23): 1017.
https://doi.org/10.1182/blood.V126.23.1017.1017
Published: 2015
Journal Articles

Transcriptome Profiling of Lenalidomide Treated Myeloma Patients Identifies an Interferon Signature Gene Response and a Novel IRF4/MYC Independent Mechanism of Resistance

Free
Paola E. Neri, MD PhD, Ines Tagoug, PhD, Li Ren, PhD, Ranjan Maity, PhD, Justin Simms, Peter Duggan, MD, Victor H Jimenez-Zepeda, MD, Jiri Slaby, MD, Howie Wu, Jackie Babich, Nizar J Bahlis, MD
Journal: Blood
Blood (2014) 124 (21): 170.
https://doi.org/10.1182/blood.V124.21.170.170
Published: 2014
Journal Articles

Cereblon (CRBN) Splice Isoform Lacking Exon 10 Attenuates Lenalidomide-Mediated Degradation of Aiolos and Is Upregulated in Immunomodulatory Drugs (IMiDs) Resistant Myeloma (MM) Patients

Free
Ranjan Maity, PhD, Paola E. Neri, MD PhD, Ines Tagoug, PhD, Li Ren, PhD, Jiri Slaby, MD, Victor H Jimenez-Zepeda, MD, Peter Duggan, MD, Justin Simms, Nizar J Bahlis, MD
Journal: Blood
Blood (2014) 124 (21): 639.
https://doi.org/10.1182/blood.V124.21.639.639
Published: 2014
Journal Articles

Lenalidomide Induced Degradation of Aiolos Disrupts RNA Polimerase I Activity and Ribosomal Biogenesis in Myeloma Cells

Free
Ines Tagoug, PhD, Jiri Slaby, MD, Paola E. Neri, MD PhD, Justin Simms, Jackie Babich, Ranjan Maity, PhD, Li Ren, PhD, Howie Wu, Nizar J Bahlis, MD
Journal: Blood
Blood (2014) 124 (21): 3422.
https://doi.org/10.1182/blood.V124.21.3422.3422
Published: 2014
Journal Articles

Lenalidomide Induces A Ribosomal Stress Response In Multiple Myeloma (MM) Cells

Free
Jiri Slaby, MD, Ines Tagoug, PhD, Paola Neri, MD, PhD, Justin Simms, Jacquelyn Babich, Kathy Gratton, Li Ren, PhD, Nizar J. Bahlis, MD
Journal: Blood
Blood (2013) 122 (21): 3161.
https://doi.org/10.1182/blood.V122.21.3161.3161
Published: 2013
Journal Articles

XPO1 Inhibition Disrupts Ribosomal Subunits Assembly and Induces Multiple Myeloma (MM) Cell Death

Free
Ines Tagoug, PhD, Paola Neri, MD, PhD, Jiri Slaby, MD, Jacquelyn Babich, Justin Simms, Kathy Gratton, Li Ren, PhD, Nizar J. Bahlis, MD
Journal: Blood
Blood (2013) 122 (21): 3165.
https://doi.org/10.1182/blood.V122.21.3165.3165
Published: 2013
Journal Articles

RNA-Sequencing Of Paired Pre-Treatment and Relapse Samples Reveals Differentially Expressed Genes Associated With Lenalidomide Resistance In Multiple Myeloma

Free
Paola Neri, MD, PhD, Kathy Gratton, Li Ren, PhD, Jiri Slaby, MD, Ines Tagoug, PhD, Nizar J. Bahlis, MD
Journal: Blood
Blood (2013) 122 (21): 530.
https://doi.org/10.1182/blood.V122.21.530.530
Published: 2013
Journal Articles

Outcomes and Correlative Studies Of a Phase I Trial With The Oral PARP1-2 Inhibitor Veliparib In Combination With Bortezomib In Patients With Relapsed Or Refractory Multiple Myeloma

Free
Paola Neri, MD, PhD, Peter Duggan, MD, FRCPC, Kathy Gratton, Li Ren, PhD, Douglas A. Stewart, MD, FRCP, Jonathan J Keats, PhD, Nizar J. Bahlis, MD
Journal: Blood
Blood (2013) 122 (21): 1978.
https://doi.org/10.1182/blood.V122.21.1978.1978
Published: 2013
Journal Articles

Role of Mir-30e in Multiple Myeloma Cells Resistance to Lenalidomide and Bortezomib

Free
Paola Neri, MD, PhD, Kathy Gratton, Li Ren, PhD, Jordan Johnson, Jiri Slaby, MD, Peter Duggan, MD, Douglas A. Stewart, MD, FRCP, Nizar J. Bahlis, MD
Journal: Blood
Blood (2012) 120 (21): 323.
https://doi.org/10.1182/blood.V120.21.323.323
Published: 2012
Journal Articles

High Cereblon Protein Expression Correlates with Improved Response and Survival in Myeloma Patients Treated with Lenalidomide

Free
Alexander Klimowicz, PhD, Paola Neri, MD, PhD, Andrew Belch, MD, Michelle Dean, Li Ren, PhD, Kathy Gratton, Jiri Slaby, MD, Jordan Johnson, Peter Duggan, MD, FRCPC, Douglas A. Stewart, MD, FRCPC, Nizar J. Bahlis, MD
Journal: Blood
Blood (2012) 120 (21): 931.
https://doi.org/10.1182/blood.V120.21.931.931
Published: 2012
Journal Articles

Lenalidomide Suppresses 5′-Cap-Independent C-MYC Translation in Multiple Myeloma Cells

Free
Jiri Slaby, MD, Jordan Johnson, Paola Neri, MD, PhD, K Gratton, Li Ren, PhD, Douglas A. Stewart, MD, FRCP, Peter Duggan, MD, FRCPC, Nizar J. Bahlis, MD
Journal: Blood
Blood (2012) 120 (21): 3943.
https://doi.org/10.1182/blood.V120.21.3943.3943
Published: 2012
Journal Articles

Phase I Study of the PARP1-2 Inhibitor Veliparib in Combination with Bortezomib in Patients with Relapsed or Refractory Multiple Myeloma

Free
Paola Neri, MD, PhD, Peter Duggan, MD, FRCPC, Kathy Gratton, Li Ren, PhD, Jordan Johnson, Jiri Slaby, MD, Douglas A. Stewart, MD, FRCP, Jonathan J Keats, PhD, Nizar J. Bahlis, MD
Journal: Blood
Blood (2012) 120 (21): 1862.
https://doi.org/10.1182/blood.V120.21.1862.1862
Published: 2012
Journal Articles

Bortezomib-induced “BRCAness” sensitizes multiple myeloma cells to PARP inhibitors

Free
Paola Neri, Li Ren, Kathy Gratton, Erin Stebner, Jordan Johnson, Alexander Klimowicz, Peter Duggan, Pierfrancesco Tassone, Adnan Mansoor, Douglas A. Stewart, Sagar Lonial, Lawrence H. Boise, Nizar J. Bahlis
Journal: Blood
Blood (2011) 118 (24): 6368–6379.
https://doi.org/10.1182/blood-2011-06-363911
Published: 2011
Includes: Supplemental data
Journal Articles

A miRNA Risk Score for the Prediction of Response to Lenalidomide in Multiple Myeloma (MM) Patients

Free
Paola Neri, MD, PhD, Andrew R Belch, MD, Jordan Johnson, Kathy J Gratton, Li Ren, PhD, Peter Duggan, MD, FRCPC, Adnan Mansoor, MD, FCPS, FRCP(C), FCAP, Douglas A. Stewart, MD, FRCP, Nizar Bahlis, MD
Journal: Blood
Blood (2011) 118 (21): 987.
https://doi.org/10.1182/blood.V118.21.987.987
Published: 2011
Journal Articles

Mir-34a Sensitizes Multiple Myeloma (MM) Cells to the Proteasome Inhibitor Bortezomib

Free
Erin Stebner, Paola Neri, MD, PhD, Jordan Johnson, Kathy J Gratton, Li Ren, PhD, Peter Duggan, MD, FRCPC, Douglas A. Stewart, MD, FRCP, Nizar Bahlis, MD
Journal: Blood
Blood (2011) 118 (21): 138.
https://doi.org/10.1182/blood.V118.21.138.138
Published: 2011
Journal Articles

Bortezomib Impairs Myeloma Cells (MM) Homologous Recombination Through Inhibition of the E2-Ubiquitin-Conjugating Enzyme UBC13

Free
Paola Neri, MD, PhD, Li Ren, PhD, Jordan Johnson, Kathy J Gratton, Erin Stebner, Carolyn J Owen, MD, FRCPC, Peter Duggan, MD, FRCPC, Douglas A. Stewart, MD, FRCP, Nizar Bahlis, MD
Journal: Blood
Blood (2011) 118 (21): 1834.
https://doi.org/10.1182/blood.V118.21.1834.1834
Published: 2011
Journal Articles

Integrin β7-mediated regulation of multiple myeloma cell adhesion, migration, and invasion

Free
Paola Neri, Li Ren, Abdel Kareem Azab, Matthew Brentnall, Kathy Gratton, Alexander C. Klimowicz, Charles Lin, Peter Duggan, Pierfrancesco Tassone, Adnan Mansoor, Douglas A. Stewart, Lawrence H. Boise, Irene M. Ghobrial, Nizar J. Bahlis
Journal: Blood
Blood (2011) 117 (23): 6202–6213.
https://doi.org/10.1182/blood-2010-06-292243
Published: 2011
Includes: Supplemental data
Journal Articles

Bortezomib Induced BRCAness Sensitizes Multiple Myeloma Cells to PARP Inhibitors

Free
Paola Neri, MD, PhD, Li Ren, PhD, Kathy Gratton, Erin Stebner, Carolyn J Owen, MD, FRCPC, Peter Duggan, MD, FRCPC, Adnan Mansoor, MD, FCPS, FRCP(C), FCAP, Douglas A. Stewart, MD, FRCP, Nizar J Bahlis, MD
Journal: Blood
Blood (2010) 116 (21): 789.
https://doi.org/10.1182/blood.V116.21.789.789
Published: 2010
Journal Articles

Integrin β7-Mediated Regulation of Multiple Myeloma Cell Adhesion, Migration and Survival.

Free
Paola Neri, M.D., Li Ren, Ph.D., Kathy Gratton, Alex Klimowicz, Ph.D., Adnan Mansoor, MD, FRCPC, Douglas A. Stewart, MD, FRCPC, Nizar J Bahlis, MD
Journal: Blood
Blood (2009) 114 (22): 949.
https://doi.org/10.1182/blood.V114.22.949.949
Published: 2009