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Abdel Kareem Azab
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Journal Articles

3D Tissue-Engineered Bone Marrow Culture Predicts Patient Response to Drugs in Multiple Myeloma

Kinan Alhallak, Amanda Jeske, Pilar De La Puente, Jennifer Sun, Mark A. Fiala, Feda Azab, Barbara Muz, Ilyas Sahin, Ravi Vij, John F. DiPersio, Abdel Kareem Azab
Journal: Blood
Blood (2021) 138 (Supplement 1): 2690.
https://doi.org/10.1182/blood-2021-153832
Published: 2021
Journal Articles

The Effects of BCMA Expression, Soluble BCMA, and Combination Therapeutics on the Anti-Tumor Activity of HPN217, a BCMA-Targeting Tri-Specific T Cell Engager Against Multiple Myeloma

Patrick P Ng, Wade Aaron, Evan Callihan, Golzar Hemmati, Che-Leung Law, Abdel Kareem Azab, Laura Sun
Journal: Blood
Blood (2021) 138 (Supplement 1): 1185.
https://doi.org/10.1182/blood-2021-151880
Published: 2021
Journal Articles

Inhibition of HIF-1a By PX-478 Normalizes Blood Vessels, Improves Drug Delivery and Suppresses Progression and Dissemination in Multiple Myeloma

Barbara Muz, PhDMSc, Katherine Wasden, Kinan Alhallak, BSc, Amanda Jeske, BS, Feda Azab, Jennifer Sun, BSc, Justin King, BS, Daniel R. Kohnen, MBA, Ravi Vij, MBBS, Abdel Kareem Azab, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3.
https://doi.org/10.1182/blood-2020-142154
Published: 2020
Journal Articles

3D-Tissue Engineered Bone Marrow (3DTEBM) Culture Retrospectively Predicts Treatment Clinical Outcomes of Multiple Myeloma Patients

Amanda Jeske, BS, Feda Azab, BPharm, Pilar De La Puente, PhD, Barbara Muz, PhDMSc, Justin King, Daniel R. Kohnen, MBA, Ravi Vij, MBBS, Abdel Kareem Azab, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1987.
https://doi.org/10.1182/blood-2018-99-118888
Published: 2018
Journal Articles

Overcoming Drug Resistance in Myeloma By Synchronized Delivery of Therapeutic and Bone Marrow Disrupting Agents By Nanoparticles Targeting Tumor-Associated Endothelium

Cinzia Federico, PhD, Barbara Muz, PhDMSc, Jennifer Sun, BSc, Kinan Alhallak, BSc, Justin King, Daniel R. Kohnen, MBA, Mark A. Fiala, BS, Aldo M. Roccaro, MDPhD, Ravi Vij, MBBS, Abdel Kareem Azab, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1931.
https://doi.org/10.1182/blood-2018-99-118251
Published: 2018
Journal Articles

Minimal Residual Disease (MRD) Analysis Using Multiparametric Flow Cytometry (MFC) and Identification of Differences in Subpopulations Using Next Generation Sequencing (NGS) in the Bone Marrow (BM) of Multiple Myeloma (MM) Patients (pts)

Sandra M. Dold, MSc, BSc, Veronika Riebl, Dagmar Wider, Marie Follo, PhD, Stefan J. Mueller, Ingrid Bartsch, Milena Pantic, PhD, Cornelius Miething, MD, Chrissoula Kiote-Schmidt, K. Martin Kortüm, MD, Mihaela Zlei, Abdel Kareem Azab, PhD, Mascha Binder, MD, Justyna Rawluk, Justus Duyster, Prof., Robert Zeiser, MD, Ralph Wäsch, MD, Monika Engelhardt, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3222.
https://doi.org/10.1182/blood-2018-99-112489
Published: 2018
Journal Articles

Targeting CD47 As a Novel Therapeutic Strategy in Multiple Myeloma

Barbara Muz, PhDMSc, Hubert D Kusdono, Justin King, Daniel Kohnen, Mark A. Fiala, BS, Ravi Vij, MDMBA, Ben Capoccia, PhD, Pamela T. Manning, PhD, Noha Nabil Salama, PhD, Abdel Kareem Azab, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3099.
https://doi.org/10.1182/blood.V130.Suppl_1.3099.3099
Published: 2017
Journal Articles

3D-Tissue Engineered Bone Marrow (3DTEBM) Culture Predicts Clinical Efficacy of Drugs Better Than Regular Culture Systems in Multiple Myeloma

Amanda Jeske, BS, Abdel Kareem Azab, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3147.
https://doi.org/10.1182/blood.V130.Suppl_1.3147.3147
Published: 2017
Journal Articles

Enhancing Proteasome-Inhibitory Activity and Specificity of Bortezomib By Endocytosis-Mediated Uptake of CD38 Targeted Nanoparticles in Multiple Myeloma

Pilar De La Puente, PhD M.Sc, Abbey Jin, Micah John Luderer, BS, MS, Christopher Egbulefu, Barbara Muz, PhDMSc, Cinzia Federico, PhD, Justin King, Daniel Kohnen, Noha Nabil Salama, PhD, Samuel Achilefu, Ravi Vij, MDMBA, Abdel Kareem Azab, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1876.
https://doi.org/10.1182/blood.V130.Suppl_1.1876.1876
Published: 2017
Journal Articles

Plasma-Derived 3D Culture for Leukemic Proliferation

Pilar De La Puente, PhD M.Sc, Ryan Soo Hoo, Michael P Rettig, PhD, Noha Nabil Salama, PhD, John F DiPersio, MD PhD, Abdel Kareem Azab, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3831.
https://doi.org/10.1182/blood.V130.Suppl_1.3831.3831
Published: 2017
Journal Articles

Epigenetic Modifications of the Bone Marrow (BM) Niche in Multiple Myeloma (MM) - a Three-Dimensional (3D) in Vitro Approach

Stefan J. Müller, PharmD, Dagmar Wider, Andreas R. Thomsen, MD, Marie Follo, PhD, Johannes M. Waldschmidt, MD, Gabriele Ihorst, Sandra M. Dold, MSc, Julia Felthaus, Johanna Senger, PhD, Julia Schüler, DVM, Justus Duyster, Abdel Kareem Azab, PhD, Martin J. Hug, PhD, Manfred Jung, PhD, Ralph Wäsch, MD, Monika Engelhardt
Journal: Blood
Blood (2017) 130 (Supplement 1): 1793.
https://doi.org/10.1182/blood.V130.Suppl_1.1793.1793
Published: 2017
Journal Articles

Anti-CD38 Targeted Nanoparticles for Drug Delivery in Multiple Myeloma

Pilar De La Puente, PhD, Abbey Jin, Micah John Luderer, BS, MS, Barbara Muz, PhD MSc, Justin A King, Ravi Vij, MD MBA, Abdel Kareem Azab, BPharm, PhD
Journal: Blood
Blood (2016) 128 (22): 2135.
https://doi.org/10.1182/blood.V128.22.2135.2135
Published: 2016
Journal Articles

Novel Flow Cytometry-Based Biomarkers Predict Recurrence in Myeloma Patients through Detection of MRD in the Bone Marrow and CTCs in Peripheral Blood

Barbara Muz, PhD MSc, Pilar De La Puente, PhD, Justin A King, Daniel R Kohnen, Ravi Vij, MD MBA, Abdel Kareem Azab, BPharm, PhD
Journal: Blood
Blood (2016) 128 (22): 2076.
https://doi.org/10.1182/blood.V128.22.2076.2076
Published: 2016
Journal Articles

Tris DBA Palladium Overcomes Hypoxia Mediated Drug Resistance in Multiple Myeloma

Pilar De La Puente, PhD, Barbara Muz, PhDMSc, Feda Azab, BPharm, Micah John Luderer, BS, MS, Jack L. Arbiser, MD, PhD, Abdel Kareem Azab, BPharm, PhD
Journal: Blood
Blood (2015) 126 (23): 2978.
https://doi.org/10.1182/blood.V126.23.2978.2978
Published: 2015
Journal Articles

Novel Method to Detect Minimal Residual Disease in Multiple Myeloma Predicts Recurrence Better Than CD138-Based Models

Barbara Muz, PhDMSc, Feda Azab, BPharm, Pilar De La Puente, PhD, Justin King, Micah John Luderer, BS, MS, Ravi Vij, MD MBA, Abdel Kareem Azab, BPharm, PhD
Journal: Blood
Blood (2015) 126 (23): 2985.
https://doi.org/10.1182/blood.V126.23.2985.2985
Published: 2015
Journal Articles

Final Results of the Phase I/II Study of Chemosensitization Using the CXCR4 Inhibitor Plerixafor in Combination with Bortezomib in Patients with Relapsed or Relapsed/Refractory Multiple Myeloma

Irene M. Ghobrial, MD, Kenneth H. Shain, MD, Jacob Laubach, MD, Patrick Henrick, James Vredenburg, MD, Pamela Crilley, MD, Michael Constantine, MD, Caroline Block, MD, Frank G. Basile, MD, Joseph Cappuccio, Abdel Kareem Azab, BPharm, PhD, Emily Lai, Aaron Caola, Ranjit Banwait, Alexandra Savell, Nikhil C. Munshi, MD, Claudia E. Paba-Prada, MD, Robert L. Schlossman, MD, Stacey Chuma, BSN, Kimberly Noonan, NP, Kenneth C. Anderson, MD, Paul G. Richardson, MD
Journal: Blood
Blood (2015) 126 (23): 4256.
https://doi.org/10.1182/blood.V126.23.4256.4256
Published: 2015
Journal Articles

Selinexor Is an Effective Cancer Treatment in Hypoxic Conditions and Synergizes with Proteasome Inhibitors to Treat Drug Resistant Multiple Myeloma

Barbara Muz, PhDMSc, Feda Azab, BPharm, Pilar De La Puente, PhD, Yosef Landesman, PhD, Abdel Kareem Azab, BPharm, PhD
Journal: Blood
Blood (2015) 126 (23): 3017.
https://doi.org/10.1182/blood.V126.23.3017.3017
Published: 2015
Journal Articles

Hypoxia Induces Pgp-Mediated Carfilzomib Resistance in Multiple Myeloma Cells and HIF Inhibition Significantly Enhances Sensitivity and Response to Carfilzomib In Vivo

Barbara Muz, PhDMSc, Joseph Abraham, Feda Azab, BPharm, Pilar De La Puente, PhD, Nicholas Potter, Benjamin Minch, Farideh Ordikhani, Noha Salama, Abdel Kareem Azab, BPharm, PhD
Journal: Blood
Blood (2015) 126 (23): 1286.
https://doi.org/10.1182/blood.V126.23.1286.1286
Published: 2015
Journal Articles

Integrin-Linked Kinase a Novel Therapeutic Target for Acute and Chronic Myeloid Leukemia

Pilar De La Puente, PhD, Ellen Weisberg, MD, Atsushi Nonami, MDPhD, Micah John Luderer, BS, MS, Richard M. Stone, MD, Junia V. Melo, MD PhD, James D Griffin, MD, Abdel Kareem Azab, BPharm, PhD
Journal: Blood
Blood (2015) 126 (23): 3694.
https://doi.org/10.1182/blood.V126.23.3694.3694
Published: 2015
Journal Articles

Tirapazamine As a Strategy to Overcome Hypoxia-Induced Drug Resistance in Multiple Myeloma

Barbara Muz, PhDMSc, Pilar De La Puente, PhD, Micah John Luderer, BS, MS, Farideh Ordikhani, Abdel Kareem Azab, BPharm, PhD
Journal: Blood
Blood (2015) 126 (23): 4436.
https://doi.org/10.1182/blood.V126.23.4436.4436
Published: 2015