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Journal Articles

Break the lifeline of AML cells

Yoko Tabe, Marina Konopleva

Blood (2021) 137 (25): 3465–3467.

https://doi.org/10.1182/blood.2021011475

Published: 2021

Journal Articles

Very long chain fatty acid metabolism is required in acute myeloid leukemia

Matthew Tcheng, Alessia Roma, Nawaz Ahmed, Richard W. Smith, Preethi Jayanth, Mark D. Minden, Aaron D. Schimmer, David A. Hess, Kristin Hope, Kevin A. Rea, Tariq A. Akhtar, Eric Bohrnsen, Angelo D’Alessandro, Al-Walid Mohsen, Jerry Vockley, Paul A. Spagnuolo

Blood (2021) 137 (25): 3518–3532.

https://doi.org/10.1182/blood.2020008551

Published: 2021

Includes: Supplemental data

Journal Articles

Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease

Blood (2021) 137 (22): 3116–3126.

https://doi.org/10.1182/blood.2020009063

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

TWIST1 preserves hematopoietic stem cell function via the CACNA1B/Ca 2+ /mitochondria axis

Nan Wang, Jing Yin, Na You, Shangda Yang, Dan Guo, Yangyang Zhao, Yongxin Ru, Xiaoyan Liu, Hui Cheng, Qian Ren, Tao Cheng, Xiaotong Ma

Blood (2021) 137 (21): 2907–2919.

https://doi.org/10.1182/blood.2020007489

Published: 2021

Includes: Supplemental data

Journal Articles

Defective palmitoylation of transferrin receptor triggers iron overload in Friedreich ataxia fibroblasts

Floriane Petit, Anthony Drecourt, Michaël Dussiot, Coralie Zangarelli, Olivier Hermine, Arnold Munnich, Agnès Rötig

Blood (2021) 137 (15): 2090–2102.

https://doi.org/10.1182/blood.2020006987

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Impact of arginine therapy on mitochondrial function in children with sickle cell disease during vaso-occlusive pain

Claudia R. Morris, Lou Ann S. Brown, Michael Reynolds, Carlton D. Dampier, Peter A. Lane, Amanda Watt, Polly Kumari, Frank Harris, Shaminy Manoranjithan, Reshika D. Mendis, Janet Figueroa, Sruti Shiva

Blood (2020) 136 (12): 1402–1406.

https://doi.org/10.1182/blood.2019003672

Published: 2020

Includes: Supplemental data

Journal Articles

Arginine for mitochondrial oxidative enzymopathy

Daniel B. Kim-Shapiro, Mark T. Gladwin

Blood (2020) 136 (12): 1376–1378.

https://doi.org/10.1182/blood.2020006732

Published: 2020

Journal Articles

MDH1-mediated malate-aspartate NADH shuttle maintains the activity levels of fetal liver hematopoietic stem cells

Blood (2020) 136 (5): 553–571.

https://doi.org/10.1182/blood.2019003940

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Mitochondrial carrier homolog 2 is necessary for AML survival

Blood (2020) 136 (1): 81–92.

https://doi.org/10.1182/blood.2019000106

Published: 2020

Includes: Supplemental data

Journal Articles

Heme-regulated eIF2α kinase in erythropoiesis and hemoglobinopathies

Jane-Jane Chen, Shuping Zhang

Blood (2019) 134 (20): 1697–1707.

https://doi.org/10.1182/blood.2019001915

Published: 2019

Journal Articles

Protein Phosphatase 2A Activation Dependent Down Regulation of PGC1-Alpha and FOXO1 Phosphorylation with OSU-2S in Human Lymphoma Cells

Sohaila Mohamed Khalil, Swagata Goswami, MSc, Xiaokui Mo, PhD MAS, Natarajan Muthusamy, DVM,PhD

Blood (2019) 134 (Supplement_1): 3977.

https://doi.org/10.1182/blood-2019-129224

Published: 2019

Journal Articles

Synergistic Effect of Carfilzomib and Metformin in Vascular Plasticity; The Emerging Role of Autophagy

Panagiotis Efentakis, PhD, Ioanna Andreadou, PhD, Panagiota-Efstathia Nikolaou, PhD, Claudius Witzler, Svenja Siemer, Eftathios Kastritis, Philip Wenzel, MD PhD, Meletios A. Dimopoulos, MD, Evangelos Terpos, MD PhD

Blood (2019) 134 (Supplement_1): 3797.

https://doi.org/10.1182/blood-2019-123522

Published: 2019

Journal Articles

The Splenic Microenvironment Is a Novel Site of Relapse Following ABT-199 Treatment

Alessandra Di Grande, BSc, Sofie Piers, Pieter Van Vlierberghe, PhD, Triona Ni Chonghaile, PhD BSc

Blood (2019) 134 (Supplement_1): 3800.

https://doi.org/10.1182/blood-2019-127970

Published: 2019

Journal Articles

Leptin Receptor As a Functional Marker for Long-Term Repopulating Hematopoietic Stem Cells

Thao Trinh, BS, Scott Cooper, MS, Arafat Aljoufi, MD, Edward F. Srour, PhD, Hal E. Broxmeyer, PhD

Blood (2019) 134 (Supplement_1): 3712.

https://doi.org/10.1182/blood-2019-128659

Published: 2019

Journal Articles

Inhibiting Very Long Chain Acyl-CoA Dehydrogenase (VLCAD) Induces Selective Leukemia Cell Death

Matthew Tcheng, BSc, Alessia Roma, BSc, Nawaz Ahmed, MSc, Richard Smith, PhD, Preethi Jayanth, PhD, Mark D. Minden, MD PhD, Rose Hurren, BSc, Aaron D Schimmer, MD PhD, Gale Bozzo, PhD, David Hess, PhD, Kristin Hope, PhD, Kevin Rea, MSc, Tariq A. Akhtar, PhD, Al-Walid Mohsen, PhD, Jerry Vockley, MD PhD, Paul A. Spagnuolo, PhD

Blood (2019) 134 (Supplement_1): 3922.

https://doi.org/10.1182/blood-2019-122262

Published: 2019

Journal Articles

Characterization of Mechanisms of Acquired Venetoclax-Insensitivity in B-Cell Precursor Acute Lymphoblastic Leukemia

Alexandra Niedermayer, MSc, Stefanie Enzenmüller, PhD, Eugen Tausch, Stephan Stilgenbauer, MD, Felix Seyfried, MD, Klaus-Michael Debatin, MD, Lüder Hinrich Meyer, MD

Blood (2019) 134 (Supplement_1): 3954.

https://doi.org/10.1182/blood-2019-126582

Published: 2019

Journal Articles

Loss of Gpr68 Enhances Hematopoietic Stem Cell Function during Aging

Xiaofei He, B.S., Caleb Hawkins, B.S., Lauren Lawley, B.S., Yan Xu, PhD, Xiang-ming Zha, PhD, Jing Fang, MD PhD

Blood (2019) 134 (Supplement_1): 3719.

https://doi.org/10.1182/blood-2019-125168

Published: 2019

Journal Articles

RUNX2 Regulates Cell Migration in T-Cell Lineage Acute Lymphoblastic Leukemia

Nitesh Devinarayan Sharma, PhD, Christian C. Nickl, Huining Kang, PhD, Wojciech Ornatowski, PhD, Stuart S. Winter, MD, Mignon L. Loh, MD, Stephen P. Hunger, MD, Ksenia Matlawska-Wasowska, PhD

Blood (2019) 134 (Supplement_1): 3947.

https://doi.org/10.1182/blood-2019-129337

Published: 2019

Journal Articles

Enhancer Rewiring Dependent Switch from BCL2 to MCL1 Dependency Predicts NOTCH1 Inhibition Response in T-ALL

Valeriya Dimitrova, Huiyoung Yun, PhD, Sayalee Potdar, Alexandria Nicole Van Scoyk, BS, Shruti Bhatt, PhD, Praveen Anand, PhD, Monica S. Nair, Jake A. Kloeber, Antonis Kokkalis, PhD MSc, Julia Frede, PhD MPhil, Johannes M. Waldschmidt, MD, Anthony G. Letai, MD PhD, David M. Weinstock, MD, Jon C. Aster, MD PhD, Jens G. Lohr, MD PhD, Birgit Knoechel, MD PhD

Blood (2019) 134 (Supplement_1): 3948.

https://doi.org/10.1182/blood-2019-131148

Published: 2019

Journal Articles

Inhibiting Mitochondria Function By Bcl-2 Inhibitor Venetoclax and Complex I Inhibitor Iacs-010759 Eliminate Leukemia Cells in Pre-Clinical AML Models

Qi Zhang, PhD, Alessia Lodi, PhD, Shannon Renee Sweeney, PhD, Lina Han, PhD, Tianyu Cai, PhD, Vinitha Mary Kuruvilla, MSc, Antonio Cavazos, Helen Ma, MS, Yoko Tabe, MD PhD, Joseph R Marszalek, PhD, Stefano Tiziani, PhD, Marina Y Konopleva, MD PhD

Blood (2019) 134 (Supplement_1): 3927.

https://doi.org/10.1182/blood-2019-124494

Published: 2019

NARROW

Break the lifeline of AML cells

Very long chain fatty acid metabolism is required in acute myeloid leukemia

Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease

TWIST1 preserves hematopoietic stem cell function via the CACNA1B/Ca 2+ /mitochondria axis

Defective palmitoylation of transferrin receptor triggers iron overload in Friedreich ataxia fibroblasts

Impact of arginine therapy on mitochondrial function in children with sickle cell disease during vaso-occlusive pain

Arginine for mitochondrial oxidative enzymopathy

MDH1-mediated malate-aspartate NADH shuttle maintains the activity levels of fetal liver hematopoietic stem cells

Mitochondrial carrier homolog 2 is necessary for AML survival

Heme-regulated eIF2α kinase in erythropoiesis and hemoglobinopathies

Protein Phosphatase 2A Activation Dependent Down Regulation of PGC1-Alpha and FOXO1 Phosphorylation with OSU-2S in Human Lymphoma Cells

Synergistic Effect of Carfilzomib and Metformin in Vascular Plasticity; The Emerging Role of Autophagy

The Splenic Microenvironment Is a Novel Site of Relapse Following ABT-199 Treatment

Leptin Receptor As a Functional Marker for Long-Term Repopulating Hematopoietic Stem Cells

Inhibiting Very Long Chain Acyl-CoA Dehydrogenase (VLCAD) Induces Selective Leukemia Cell Death

Characterization of Mechanisms of Acquired Venetoclax-Insensitivity in B-Cell Precursor Acute Lymphoblastic Leukemia

Loss of Gpr68 Enhances Hematopoietic Stem Cell Function during Aging

RUNX2 Regulates Cell Migration in T-Cell Lineage Acute Lymphoblastic Leukemia

Enhancer Rewiring Dependent Switch from BCL2 to MCL1 Dependency Predicts NOTCH1 Inhibition Response in T-ALL

Inhibiting Mitochondria Function By Bcl-2 Inhibitor Venetoclax and Complex I Inhibitor Iacs-010759 Eliminate Leukemia Cells in Pre-Clinical AML Models

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American Society of Hematology

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American Society of Hematology

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