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Journal Articles

All-trans retinoic acid mitigates IL-1β-driven NEU1-mediated megakaryocyte desialylation and dysfunction in immune thrombocytopenia

Peng Zhao, Jing-Li Han, Hai-Xia Fu, Zhuo-Yu An, Yue Jin, Lan-Ping Xu, Xiaojun Huang, Xiaohui Zhang

Blood (2025) 146 (Supplement 1): 1243.

https://doi.org/10.1182/blood-2025-1243

Published: 2025

Journal Articles

Novel insights from the largest cohort to date: Elucidating risk factors, clinical outcomes, and prognostic predictors in autoimmune hemolytic anemia following allogeneic hematopoietic stem cell transplantation

Liqian Zhang, Zhuo-Yu An, Peng Zhao, Hai-Xia Fu, Yuanyuan Zhang, Xiao-Dong Mo, Fengrong Wang, Yuqian Sun, Meng Lv, Xiangyu Zhao, YuHong Chen, Yu Wang, Ying-Jun Chang, Lan-Ping Xu, Xiaojun Huang, Xiaohui Zhang

Blood (2025) 146 (Supplement 1): 6046.

https://doi.org/10.1182/blood-2025-6046

Published: 2025

Journal Articles

Stratos: An AI-driven biomarker signature for prognostic risk stratification in transplant-associated thrombotic microangiopathy - a nationwide, multicenter study

Blood (2025) 146 (Supplement 1): 120.

https://doi.org/10.1182/blood-2025-120

Published: 2025

Journal Articles

Iguratimod plus low-dose rituximab as second-line treatment in adults with primary immune thrombocytopenia: A multicenter, open-label, randomized, controlled, Phase 2 trial

Qiu-Sha Huang, Zhuo-Yu An, Peng Zhao, Qi Chen, Jin Wu, Hai-Xia Fu, Yujun Dong, Hongmei Jing, Liping Dou, Hui Liu, Yi Liu, Lanping Xu, Xiaojun Huang, Xiaohui Zhang

Blood (2025) 146 (Supplement 1): 3044.

https://doi.org/10.1182/blood-2025-3044

Published: 2025

Journal Articles

Development and prospective validation of a prognostic model for diffuse alveolar hemorrhage after allogeneic hematopoietic stem cell transplantation

Qiu-Sha Huang, Zhuo-Yu An, Peng Zhao, Xiaolu Zhu, Yun He, Hai-Xia Fu, Fengrong Wang, Yuanyuan Zhang, Xiao-Dong Mo, Wei Han, Chen-hua Yan, Ting-ting Han, Yao Chen, Yu Wang, Ying-Jun Chang, Xiang-Yu Zhao, Lanping Xu, Xiaojun Huang, Xiaohui Zhang

Blood (2025) 146 (Supplement 1): 4276.

https://doi.org/10.1182/blood-2025-4276

Published: 2025

Journal Articles

The selective JAK1 inhibitor upadacitinib restores impaired neutrophil chemotaxis in the proplatelet formation of immune thrombocytopenia

Qiu-Sha Huang, Qing-Yuan Qu, Zhuo-Yu An, Peng Zhao, Qi Chen, Jin Wu, Hai-Xia Fu, Ying-Jun Chang, Xiang-Yu Zhao, Lanping Xu, Xiaojun Huang, Xiaohui Zhang

Blood (2025) 146 (Supplement 1): 197.

https://doi.org/10.1182/blood-2025-197

Published: 2025

Journal Articles

Management and outcomes of acute coronary syndromes in patients with immune thrombocytopenia: A single-center real-world study

Jin Wu, Liqin Cao, Qiu-Sha Huang, Zhuo-Yu An, Peng Zhao, Hai-Xia Fu, Xiaohui Zhang

Blood (2025) 146 (Supplement 1): 4822.

https://doi.org/10.1182/blood-2025-4822

Published: 2025

Journal Articles

The JAK1/2 inhibitor baricitinib revealed unique immune biomarkers in multirefractory immune thrombocytopenia patients

Zhuo-Yu An, Peng Zhao, Hai-Xia Fu, Xiaolu Zhu, Yun He, Qiu-Sha Huang, Xiaohui Zhang

Blood (2025) 146 (Supplement 1): 4820.

https://doi.org/10.1182/blood-2025-4820

Published: 2025

Journal Articles

Baricitinib reveals LGALS3BP as a novel pathogenic factor and therapeutic target in immune thrombocytopenia

Kexin Shen, Jingli Han, Zhuo-Yu An, Peng Zhao, Hai-Xia Fu, Qiu-Sha Huang, Jin Wu, Li-Ping Yang, Yuanyuan Zhang, Ying-jun Chang, Xiangyu Zhao, Yu Wang, Lan-Ping Xu, Xiaojun Huang, Xiaohui Zhang

Blood (2025) 146 (Supplement 1): 846.

https://doi.org/10.1182/blood-2025-846

Published: 2025

Journal Articles

Beyond the unknown: Leveraging machine learning to predict adverse outcomes in pregnant women with aplastic anemia from a representative nationwide cohort

Blood (2025) 146 (Supplement 1): 1413.

https://doi.org/10.1182/blood-2025-1413

Published: 2025

Journal Articles

Tandem CAR-T-Cell Therapy Targeting CD5 and CD7: Facilitating Condition-Free Engraftment of Epitope-Edited Allogeneic HSCs

Guo-Ling Wang, Ting Wang, Jing-Li Han, Li-Xin Wu, Xuan-Zhong Chen, Zhuo-Yu An, Chen-Cong Wang, Peng Zhao, Lu-Lu Wang, Meng-Tong Zang, Wei Zheng, Hai-Xia Fu, Jia Feng, Hong-Yu Zhang, Xiaohui Zhang

Blood (2024) 144 (Supplement 1): 2041.

https://doi.org/10.1182/blood-2024-208043

Published: 2024

Journal Articles

β2-Adrenergic Receptor Agonist Terbutaline Regulates Macrophage Polarization Via HMGB1 in Immune Thrombocytopenia

Qiuyu Guo, Ye-Jun Wu, Gao-Chao Zhang, Yu-Xiu Chen, Meng-Lin Li, Meng-Yu Xiao, Jian-Ying Zhou, Lu-Lu Wang, Meng-Tong Zang, Zhuo-Yu An, Hai-Xia Fu, Xiao-Jun Huang, Xiao-Hui Zhang

Blood (2024) 144 (Supplement 1): 425.

https://doi.org/10.1182/blood-2024-203555

Published: 2024

Journal Articles

Genetic Associations and Platelet Count Trajectories in Gestational Thrombocytopenia and Immune Thrombocytopenia during Pregnancy

Kexin Shen, Chen Zhao, Lulu Wang, Mengtong Zang, Peng Zhao, Zhuo-Yu An, Xiaolu Zhu, Qiusha Huang, HaiXia Fu, Xiaojun Huang, Xiaohui Zhang

Blood (2024) 144 (Supplement 1): 2566.

https://doi.org/10.1182/blood-2024-205459

Published: 2024

Journal Articles

Effects of Low-Molecular-Weight Heparin on Pregnancy Outcomes in Protein S Deficiency: A Prospective, Randomized Controlled Phase II Clinical

Mengtong Zang, HaiXia Fu, Yuxiu Chen, Menglin Li, Jianying Zhou, Mengyu Xiao, Lulu Wang, Zhuo-Yu An, Xiaolu Zhu, Yun He, Chen-Cong Wang, KaiYan Liu, LanPing Xu, Xiao Jun Huang, Xiaohui Zhang

Blood (2024) 144 (Supplement 1): 300.

https://doi.org/10.1182/blood-2024-204674

Published: 2024

Journal Articles

Projected Global Trends in Hematological Malignancies: Incidence, Mortality, and Disability-Adjusted Life Years from 2020 to 2030

Zhuo-Yu An, Haixia Fu, Yun He, Xiaolu Zhu, Qiu-Sha Huang, Jin Wu, Kaiyan Liu, Xiaohui Zhang

Blood (2023) 142 (Supplement 1): 3810.

https://doi.org/10.1182/blood-2023-187856

Published: 2023

Journal Articles

Tacrolimus and Danazol Combination As a Second-Line Therapeutic Strategy for Steroid-Resistant or Relapsed Immune Thrombocytopenia: A Prospective, Randomized, Multicenter, Open-Label Study

Zhuo-Yu An, Yun He, Xiao-lu Zhu, Qiu-Sha Huang, Jin Wu, Haixia Fu, Yuan-Yuan Zhang, Ying-jun Chang, Xiangyu Zhao, Kaiyan Liu, Xiaohui Zhang

Blood (2023) 142 (Supplement 1): 2582.

https://doi.org/10.1182/blood-2023-188139

Published: 2023

Journal Articles

Evaluation of ISTH Severe Bleeding Criteria and Development of a Mortality Prognosis Model for Hospitalized Immune Thrombocytopenia Patients: A Multicenter, Retrospective and Prospective Cohort Study

Zhuo-Yu An, Haixia Fu, Yun He, Xiaolu Zhu, Jin Wu, Qiu-Sha Huang, Kaiyan Liu, Xiaohui Zhang

Blood (2023) 142 (Supplement 1): 2580.

https://doi.org/10.1182/blood-2023-187920

Published: 2023

Journal Articles

Real-World Study of the Use of Iguratimod to Treat Chronic/Refractory ITP

Blood (2022) 140 (Supplement 1): 5567–5568.

https://doi.org/10.1182/blood-2022-167362

Published: 2022

Journal Articles

Endothelial cell-derived angiopoietin-like protein 2 supports hematopoietic stem cell activities in bone marrow niches

Zhuo Yu, Wenqian Yang, Xiaoxiao He, Chiqi Chen, Wenrui Li, Limin Zhao, Ligen Liu, Junling Liu, Li Xie, Yaping Zhang, Junke Zheng

Blood (2022) 139 (10): 1529–1540.

https://doi.org/10.1182/blood.2021011644

Published: 2022

Includes: Supplemental data

Journal Articles

Tacrolimus Plus High-Dose Dexamethasone Versus High-Dose Dexamethasone Alone As First-Line Treatment for Adult Immune Thrombocytopenia: The Phase 2, Open Label, Randomized Trial (TARGET 020)

Blood (2021) 138 (Supplement 1): 13.

https://doi.org/10.1182/blood-2021-152111

Published: 2021

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All-trans retinoic acid mitigates IL-1β-driven NEU1-mediated megakaryocyte desialylation and dysfunction in immune thrombocytopenia

Novel insights from the largest cohort to date: Elucidating risk factors, clinical outcomes, and prognostic predictors in autoimmune hemolytic anemia following allogeneic hematopoietic stem cell transplantation

Stratos: An AI-driven biomarker signature for prognostic risk stratification in transplant-associated thrombotic microangiopathy - a nationwide, multicenter study

Iguratimod plus low-dose rituximab as second-line treatment in adults with primary immune thrombocytopenia: A multicenter, open-label, randomized, controlled, Phase 2 trial

Development and prospective validation of a prognostic model for diffuse alveolar hemorrhage after allogeneic hematopoietic stem cell transplantation

The selective JAK1 inhibitor upadacitinib restores impaired neutrophil chemotaxis in the proplatelet formation of immune thrombocytopenia

Management and outcomes of acute coronary syndromes in patients with immune thrombocytopenia: A single-center real-world study

The JAK1/2 inhibitor baricitinib revealed unique immune biomarkers in multirefractory immune thrombocytopenia patients

Baricitinib reveals LGALS3BP as a novel pathogenic factor and therapeutic target in immune thrombocytopenia

Beyond the unknown: Leveraging machine learning to predict adverse outcomes in pregnant women with aplastic anemia from a representative nationwide cohort

Tandem CAR-T-Cell Therapy Targeting CD5 and CD7: Facilitating Condition-Free Engraftment of Epitope-Edited Allogeneic HSCs

β2-Adrenergic Receptor Agonist Terbutaline Regulates Macrophage Polarization Via HMGB1 in Immune Thrombocytopenia

Genetic Associations and Platelet Count Trajectories in Gestational Thrombocytopenia and Immune Thrombocytopenia during Pregnancy

Effects of Low-Molecular-Weight Heparin on Pregnancy Outcomes in Protein S Deficiency: A Prospective, Randomized Controlled Phase II Clinical

Projected Global Trends in Hematological Malignancies: Incidence, Mortality, and Disability-Adjusted Life Years from 2020 to 2030

Tacrolimus and Danazol Combination As a Second-Line Therapeutic Strategy for Steroid-Resistant or Relapsed Immune Thrombocytopenia: A Prospective, Randomized, Multicenter, Open-Label Study

Evaluation of ISTH Severe Bleeding Criteria and Development of a Mortality Prognosis Model for Hospitalized Immune Thrombocytopenia Patients: A Multicenter, Retrospective and Prospective Cohort Study

Real-World Study of the Use of Iguratimod to Treat Chronic/Refractory ITP

Endothelial cell-derived angiopoietin-like protein 2 supports hematopoietic stem cell activities in bone marrow niches

Tacrolimus Plus High-Dose Dexamethasone Versus High-Dose Dexamethasone Alone As First-Line Treatment for Adult Immune Thrombocytopenia: The Phase 2, Open Label, Randomized Trial (TARGET 020)

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American Society of Hematology

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