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Journal Articles

Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease

Blood (2021) 137 (22): 3116–3126.

https://doi.org/10.1182/blood.2020009063

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Quantification of Anti-Sickling Effect of Aes-103 in Sickle Cell Disease Using an in Vitro Microfluidic Assay

E. Du, PhD, Laurel Mendelsohn, BS, James S. Nichols, RN, Ming Dao, PhD, Gregory J. Kato, MD

Blood (2014) 124 (21): 2699.

https://doi.org/10.1182/blood.V124.21.2699.2699

Published: 2014

Journal Articles

Iron, Expression of the Pattern Recognition Receptor-Inflammasome System, and Early Death in Adults with Sickle Cell Disease

Eduard J. van Beers, MD PhD, Yanqin Yang, MS, Nalini Raghavachari, PhD, Xin Tian, PhD, Darlene Allen, MT(ASCP), James S. Nichols, RN, Laurel Mendelsohn, BS, Sergei A. Nekhai, PhD, Victor R. Gordeuk, MD, James G. Taylor VI, MD, Gregory J. Kato, MD

Blood (2014) 124 (21): 2702.

https://doi.org/10.1182/blood.V124.21.2702.2702

Published: 2014

Journal Articles

Imaging flow cytometry documents incomplete resistance of human sickle F-cells to ex vivo hypoxia-induced sickling

Kleber Yotsumoto Fertrin, Eduard J. van Beers, Leigh Samsel, Laurel G. Mendelsohn, Rehan Saiyed, James S. Nichols, David A. Hepp, Christine A. Brantner, Mathew P. Daniels, J. Philip McCoy, Gregory J. Kato

Blood (2014) 124 (4): 658–660.

https://doi.org/10.1182/blood-2014-03-559054

Published: 2014

Journal Articles

Imaging Flow Cytometry and Microfluidic Flow Assays Demonstrate Heterocellular Aggregation Of Immature Sickle Erythrocytes To Neutrophils Via Mac-1/VLA-4 Interactions

Venina Marcela Dominical, M.Sc., Leigh Samsel, MS, Daiana Morelli Vital, B.Sc., James S Nichols, RN, Vanessa Tonin Garrido, Sara T O Saad, MD, PhD, Fernando Ferreira Costa, MD, PhD, J. Philip McCoy, PhD, Nicola Conran, PhD, Gregory J. Kato, M.D.

Blood (2013) 122 (21): 318.

https://doi.org/10.1182/blood.V122.21.318.318

Published: 2013

Journal Articles

The Anti-Sickling Agent Aes-103 Decreases Sickle Erythrocyte Fragility, Hypoxia-Induced Sickling and Hemolysis In Vitro

Laurel G. Mendelsohn, B.S., Leah Pedoeim, B.S., Yekai Kevin Wang, B.S., Rehan Saiyed, B.S., Christine A. Brantner, PhD, Mathew P. Daniels, PhD, James S. Nichols, RN, Xunde Wang, Ph.D., Eduard J. van Beers, MD, PhD, Gregory J. Kato, M.D.

Blood (2013) 122 (21): 940.

https://doi.org/10.1182/blood.V122.21.940.940

Published: 2013

Journal Articles

Imaging Flow Cytometry Documents Incomplete Resistance Of F-Cells To Hypoxia-Induced Sickling In Blood Samples From Patients With Sickle Cell Anemia

Kleber Yotsumoto Fertrin, MD, PhD, Eduard J. van Beers, MD, PhD, Leigh Samsel, MS, Laurel G. Mendelsohn, B.S., Rehan Saiyed, B.S., James S. Nichols, RN, David A. Hepp, Christine A. Brantner, PhD, Mathew P. Daniels, PhD, J. Philip McCoy, PhD, Gregory J. Kato, M.D.

Blood (2013) 122 (21): 183.

https://doi.org/10.1182/blood.V122.21.183.183

Published: 2013

Journal Articles

Imaging Flow Cytometry for Fully Automated Quantification of Percentage of Sickled Cells in Sickle Cell Anemia.

Eduard J. van Beers, MD, PhD, Leigh Samsel, MS, Laurel G. Mendelsohn, M.S., Rehan Saiyed, BS, James S Nichols, RN, J. Philip McCoy, Jr., PhD, Gregory J. Kato, M.D.

Blood (2012) 120 (21): 2105.

https://doi.org/10.1182/blood.V120.21.2105.2105

Published: 2012

Journal Articles

Effect of Aes-103 Anti-Sickling Agent On Oxygen Affinity and Stability of Red Blood Cells From Patients with Sickle Cell Anemia

Laurel G. Mendelsohn, M.S., Leah Pedoeim, BS, Eduard J. van Beers, MD, PhD, Rehan Saiyed, BS, James S Nichols, RN, Xunde Wang, Ph.D., Gregory J. Kato, M.D.

Blood (2012) 120 (21): 85.

https://doi.org/10.1182/blood.V120.21.85.85

Published: 2012

Journal Articles

Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease

Gregory J. Kato, Vicki McGowan, Roberto F. Machado, Jane A. Little, James Taylor, VI, Claudia R. Morris, James S. Nichols, Xunde Wang, Mirjana Poljakovic, Sidney M. Morris, Jr, Mark T. Gladwin

Blood (2006) 107 (6): 2279–2285.

https://doi.org/10.1182/blood-2005-06-2373

Published: 2006

Includes: Supplemental data

Journal Articles

Lactate Dehydrogenase as a Biomarker of Hemolysis-Associated Nitric Oxide Resistance, Priapism, Leg Ulceration, Pulmonary Hypertension and Death in Patients with Sickle Cell Disease.

Gregory J. Kato, MD, Vicki McGowan, BS, Roberto F. Machado, MD, Jane A. Little, MD, James Taylor, VI, MD, Claudia R. Morris, MD, James S. Nichols, RN, Xunde Wang, PhD, Mirjana Poljakovic, PhD, Sidney M. Morris, Jr., PhD, Mark T. Gladwin, MD

Blood (2005) 106 (11): 3188.

https://doi.org/10.1182/blood.V106.11.3188.3188

Published: 2005

Journal Articles

The Sickle Cell-Pulmonary Hypertension Screening Study: ECHO Findings at Two-Years of Follow Up.

Oswaldo Castro, MD, Gregory Kato, MD, Vandana Sachdev, MD, Roberto Machado, MD, Inez Ernst, RN, Wynona A. Coles, RRT, James S. Nichols, RN, Lori A. Hunter, RN, Mark T. Gladwin, MD

Blood (2005) 106 (11): 314.

https://doi.org/10.1182/blood.V106.11.314.314

Published: 2005

Journal Articles

Pulmonary Hypertension in Sickle Cell Disease: Cardiopulmonary Evaluation and Response to Chronic Phosphodiesterase 5 Inhibitor Therapy.

Roberto F. Machado, MD, Sabrina E. Martyr, BS, Anastasia Anthi, MD, Gregory J. Kato, MD, Lori A. Hunter, RN, Wynona A. Coles, RRT, James S. Nichols, RN, Oswaldo L. Castro, MD, Mark T. Gladwin, MD

Blood (2004) 104 (11): 235.

https://doi.org/10.1182/blood.V104.11.235.235

Published: 2004

NARROW

Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease

Quantification of Anti-Sickling Effect of Aes-103 in Sickle Cell Disease Using an in Vitro Microfluidic Assay

Iron, Expression of the Pattern Recognition Receptor-Inflammasome System, and Early Death in Adults with Sickle Cell Disease

Imaging flow cytometry documents incomplete resistance of human sickle F-cells to ex vivo hypoxia-induced sickling

Imaging Flow Cytometry and Microfluidic Flow Assays Demonstrate Heterocellular Aggregation Of Immature Sickle Erythrocytes To Neutrophils Via Mac-1/VLA-4 Interactions

The Anti-Sickling Agent Aes-103 Decreases Sickle Erythrocyte Fragility, Hypoxia-Induced Sickling and Hemolysis In Vitro

Imaging Flow Cytometry Documents Incomplete Resistance Of F-Cells To Hypoxia-Induced Sickling In Blood Samples From Patients With Sickle Cell Anemia

Imaging Flow Cytometry for Fully Automated Quantification of Percentage of Sickled Cells in Sickle Cell Anemia.

Effect of Aes-103 Anti-Sickling Agent On Oxygen Affinity and Stability of Red Blood Cells From Patients with Sickle Cell Anemia

Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease

Lactate Dehydrogenase as a Biomarker of Hemolysis-Associated Nitric Oxide Resistance, Priapism, Leg Ulceration, Pulmonary Hypertension and Death in Patients with Sickle Cell Disease.

The Sickle Cell-Pulmonary Hypertension Screening Study: ECHO Findings at Two-Years of Follow Up.

Pulmonary Hypertension in Sickle Cell Disease: Cardiopulmonary Evaluation and Response to Chronic Phosphodiesterase 5 Inhibitor Therapy.

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American Society of Hematology

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American Society of Hematology

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