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Journal Articles

SASH3 variants cause a novel form of X-linked combined immunodeficiency with immune dysregulation

Blood (2021) 138 (12): 1019–1033.

https://doi.org/10.1182/blood.2020008629

Published: 2021

Includes: Supplemental data

Journal Articles

EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene

Rajesh Somasundaram, Christina T. Jensen, Johanna Tingvall-Gustafsson, Josefine Åhsberg, Kazuki Okuyama, Mahadesh Prasad, James R. Hagman, Xun Wang, Shamit Soneji, Tobias Strid, Jonas Ungerbäck, Mikael Sigvardsson

Blood (2021) 137 (22): 3037–3049.

https://doi.org/10.1182/blood.2020009564

Published: 2021

Includes: Supplemental data

Journal Articles

Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL

Blood (2021) 137 (18): 2463–2480.

https://doi.org/10.1182/blood.2019004547

Published: 2021

Includes: Supplemental data

Journal Articles

JAK2 -V617F and interferon-α induce megakaryocyte-biased stem cells characterized by decreased long-term functionality

Tata Nageswara Rao, Nils Hansen, Jan Stetka, Damien Luque Paz, Milena Kalmer, Julian Hilfiker, Max Endele, Nouraiz Ahmed, Lucia Kubovcakova, Margareta Rybarikova, Hui Hao-Shen, Florian Geier, Christian Beisel, Stefan Dirnhofer, Timm Schroeder, Tim H. Brümmendorf, Dominik Wolf, Steffen Koschmieder, Radek C. Skoda

Blood (2021) 137 (16): 2139–2151.

https://doi.org/10.1182/blood.2020005563

Published: 2021

Includes: Supplemental data

Journal Articles

Hematopoietic Stem Cells Increase Quiescence during Aging

Larisa V. Kovtonyuk, PhD, Peter Ashcroft, PhD, Gianluca Spaltro, MD, Nageswara Rao Tata, Radek C. Skoda, Sebastian Bonhoeffer, Markus G. Manz, Prof.Dr.MD

Blood (2019) 134 (Supplement_1): 2484.

https://doi.org/10.1182/blood-2019-130668

Published: 2019

Journal Articles

O-Glcnacylation Is Essential for Erythropoiesis

Matthew P Parker, BS, Halyna Fedosyuk, MS, Lesya V Novikova, PhD, Zhen Zhang, PhD, Chad Slawson, PhD, Kenneth R Peterson, PhD

Blood (2019) 134 (Supplement_1): 2218.

https://doi.org/10.1182/blood-2019-129468

Published: 2019

Journal Articles

Leukemogenic Functions of Mutant ASXL1 Are Regulated By CDK-Mediated Phosphorylation

Shuhei Asada, MD PhD, Susumu Goyama, MD PhD, Reina Takeda, MD, Keita Yamamoto, MD, Hiroko Kozuka-Hata, PhD, Masaaki Oyama, PhD, Daichi Inoue, MD PhD, Hiroaki Honda, MD PhD, Toshio Kitamura, MD PhD

Blood (2019) 134 (Supplement_1): 731.

https://doi.org/10.1182/blood-2019-125959

Published: 2019

Journal Articles

Mutant ASXL1 Promotes Expansion of the Phenotypic Hematopoietic Stem Cell Compartment

Takeshi Fujino, MD, Susumu Goyama, MD PhD, Yuki Sugiura, PhD, Daichi Inoue, MD PhD, Satoshi Yamasaki, PhD, Akiko Matsumoto, Naru Sato, MD, Hironobu Morinaga, PhD, Shiori Shikata, Tomofusa Fukuyama, MD PhD, Yosuke Tanaka, PhD, Shuhei Asada, MD PhD, Tsuyoshi Fukushima, MD PhD, Hiroaki Honda, MD PhD, Emi K Nishimura, MD PhD, Tatsuhiro Shibata, MD PhD, Makoto Suematsu, MD PhD, Toshio Kitamura, MD PhD

Blood (2019) 134 (Supplement_1): 821.

https://doi.org/10.1182/blood-2019-127904

Published: 2019

Journal Articles

Notch1 mutation in B Chronic Lymphocytic Lymphocytes Induces Proliferation through Cell Cycle G1/S Phase-Specific Cyclin Overexpression

Ana M Hurtado López, Tzu Hua Chen-Liang, María Zurdo, Anna Puiggros, PhD, Andrea Gómez-Llonín, B.Sc., María-Dolores García-Malo, MD, Francisco José Ortuño, Vicente Vicente Garcia, MD PhD, Blanca Espinet, PhD, Andres Jerez

Blood (2019) 134 (Supplement_1): 851.

https://doi.org/10.1182/blood-2019-127960

Published: 2019

Journal Articles

KIFC1 Mediates Centrosome Clustering Prior to Proplatelet Formation from Megakaryocytes

Adrian R. Wilkie, PhD, Leila J. Noetzli, PhD, Genevieve Couldwell, Anthony R. Sciaudone, Anjana Ray, PhD, Kellie R. Machlus, PhD, Joseph E. Italiano, Jr., BS, PhD

Blood (2019) 134 (Supplement_1): 721.

https://doi.org/10.1182/blood-2019-130803

Published: 2019

Journal Articles

DNMT3A with Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

Kartika Venugopal, MS, Daniil E Shabashvili, PhD, Jianping Li, MD, Luisa M Posada, Richard Lynn Bennett, PhD, Yang Feng, MS, Daphne Dupere Richer, PhD, Alberto Riva, PhD, Santhi Pondugula, PhD, Jonathan E. Bird, PhD, Jonathan D. Licht, MD, Olga A Guryanova, MD PhD

Blood (2019) 134 (Supplement_1): 535.

https://doi.org/10.1182/blood-2019-128213

Published: 2019

Journal Articles

PRMT5 Inhibition Modulates E2F1 Methylation and Gene Regulatory Networks Leading to Therapeutic Efficacy in JAK2VF Mutant MPN

Blood (2019) 134 (Supplement_1): 473.

https://doi.org/10.1182/blood-2019-127122

Published: 2019

Journal Articles

Deconstructing the Clonal Advantage and Clonal Stability of 5q- Candidate Genes in Del(5q) MDS on a Single Cell Level

Ursula S.A. Stalmann, MD, Fabio Ticconi, MSc, Ronghui Li, MSc, Aaron B. Wong, PhD, Glenn Cowley, PhD, David E. Root, PhD, Dirk Heckl, PhD, Inge Snoeren, MSc, Sergio Martinez, PhDMSc, Tim H Brümmendorf, MD, Andreas Schuppert, PhD, Ivan Costa, PhD, Benjamin L. Ebert, MD PhD, Rebekka K. Schneider, MD PhD

Blood (2019) 134 (Supplement_1): 559.

https://doi.org/10.1182/blood-2019-122588

Published: 2019

Journal Articles

Autism-Associated Chromatin Remodeler CHD8 Governs the Survival and Differentiation of Hematopoietic Stem/Progenitor Cells

Zhaowei Tu, PhD, Chen Wang, MSc, Chuntao Zhao, PhD, Lei Huang, PhD, Nathan Salomonis, PhD, Richard Q Lu, PhD, Yi Zheng, PhD

Blood (2019) 134 (Supplement_1): 1191.

https://doi.org/10.1182/blood-2019-127313

Published: 2019

Journal Articles

Critical Requirement of U2AF1 in the Maintenance and Function of Hematopoietic Stem Cells

Avik Dutta, PhD, Yue Yang, PhD, Bao Le, Golam Mohi, PhD

Blood (2019) 134 (Supplement_1): 1195.

https://doi.org/10.1182/blood-2019-132007

Published: 2019

Journal Articles

Preclinical Activity of the MPS1 Inhibitor S81694 in Acute Lymphoblastic Leukemia (ALL)

Anna Kaci, PhD, Emilie Adiceam, Melanie Dupont, Marine Garrido, Jeannig Berrou, Hanane Djamai, Andre Baruchel, Mike Burbridge, Claude Gardin, Herve Dombret, MD PhD, Thorsten Braun, MD

Blood (2019) 134 (Supplement_1): 2631.

https://doi.org/10.1182/blood-2019-125641

Published: 2019

Journal Articles

Investigation of Cell-Contact Dependent Alterations in Immune Synapse Formation between T Cells and BCP-ALL Cells

Britta Wenske, PhD, Lothar Marischen, PhD, Julia Welzenbach, André Heimbach, PhD, Per Hoffmann, PhD, Selim Corbacioglu, MD, David A Williams, MD, Anja Troeger, MD

Blood (2019) 134 (Supplement_1): 2754.

https://doi.org/10.1182/blood-2019-128835

Published: 2019

Journal Articles

The Dual Cell Cycle Kinase Inhibitor JNJ-7706621 Reverses Resistance to CD37 Targeted Radioimmunotherapy in Activated B Cell like Diffuse Large B Cell Lymphoma Cell Lines

Gro Elise Rødland, PhD, Katrine Melhus, Roman Generalov, Sania Gilani, Francesco Bertoni, MD, Jostein Dahle, PhD, Randi Syljuåsen, PhD, Sebastian Patzke, PhD

Blood (2019) 134 (Supplement_1): 2574.

https://doi.org/10.1182/blood-2019-123287

Published: 2019

Journal Articles

Marcks Is a Critical Downstream Mediator of IL-1-Driven AML Progression

Mona M.Hosseini, BS, Hsin-Yun Lin, MS, Gabby Dewson, BA, Ruthey Vivier, Anupriya Agarwal, PhD

Blood (2019) 134 (Supplement_1): 2679.

https://doi.org/10.1182/blood-2019-129427

Published: 2019

Journal Articles

Identification of Potent Quiescent Human Hematopoietic Stem Cells Using Mitochondrial Profile

Jiajing Qiu, PhD, Jana Gjini, Miao Lin, Msc, Tasleem Arif, PhD, Saghi Ghaffari, PhD MD

Blood (2019) 134 (Supplement_1): 5602.

https://doi.org/10.1182/blood-2019-129913

Published: 2019

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SASH3 variants cause a novel form of X-linked combined immunodeficiency with immune dysregulation

EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene

Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL

JAK2 -V617F and interferon-α induce megakaryocyte-biased stem cells characterized by decreased long-term functionality

Hematopoietic Stem Cells Increase Quiescence during Aging

O-Glcnacylation Is Essential for Erythropoiesis

Leukemogenic Functions of Mutant ASXL1 Are Regulated By CDK-Mediated Phosphorylation

Mutant ASXL1 Promotes Expansion of the Phenotypic Hematopoietic Stem Cell Compartment

Notch1 mutation in B Chronic Lymphocytic Lymphocytes Induces Proliferation through Cell Cycle G1/S Phase-Specific Cyclin Overexpression

KIFC1 Mediates Centrosome Clustering Prior to Proplatelet Formation from Megakaryocytes

DNMT3A with Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

PRMT5 Inhibition Modulates E2F1 Methylation and Gene Regulatory Networks Leading to Therapeutic Efficacy in JAK2VF Mutant MPN

Deconstructing the Clonal Advantage and Clonal Stability of 5q- Candidate Genes in Del(5q) MDS on a Single Cell Level

Autism-Associated Chromatin Remodeler CHD8 Governs the Survival and Differentiation of Hematopoietic Stem/Progenitor Cells

Critical Requirement of U2AF1 in the Maintenance and Function of Hematopoietic Stem Cells

Preclinical Activity of the MPS1 Inhibitor S81694 in Acute Lymphoblastic Leukemia (ALL)

Investigation of Cell-Contact Dependent Alterations in Immune Synapse Formation between T Cells and BCP-ALL Cells

The Dual Cell Cycle Kinase Inhibitor JNJ-7706621 Reverses Resistance to CD37 Targeted Radioimmunotherapy in Activated B Cell like Diffuse Large B Cell Lymphoma Cell Lines

Marcks Is a Critical Downstream Mediator of IL-1-Driven AML Progression

Identification of Potent Quiescent Human Hematopoietic Stem Cells Using Mitochondrial Profile

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