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Journal Articles

How I treat pediatric acute myeloid leukemia

Jeffrey E. Rubnitz, Gertjan J. L. Kaspers
Journal: Blood
Blood (2021) 138 (12): 1009–1018.
https://doi.org/10.1182/blood.2021011694
Published: 2021
Journal Articles

Cryptic insertion of KMT2A , a rare t(9;11) variant

Nada Assaf, Christine Terré
Journal: Blood
Blood (2021) 137 (13): 1843.
https://doi.org/10.1182/blood.2020010442
Published: 2021
Journal Articles

CLEC12A and CD33 coexpression as a preferential target for pediatric AML combinatorial immunotherapy

Semjon Willier, Paula Rothämel, Maximilian Hastreiter, Jonas Wilhelm, Dana Stenger, Franziska Blaeschke, Meino Rohlfs, Theresa Kaeuferle, Irene Schmid, Michael H. Albert, Vera Binder, Marion Subklewe, Christoph Klein, Tobias Feuchtinger
Journal: Blood
Blood (2021) 137 (8): 1037–1049.
https://doi.org/10.1182/blood.2020006921
Published: 2021
Includes: Supplemental data
Journal Articles

Immunogenomic identification and characterization of granulocytic myeloid-derived suppressor cells in multiple myeloma

Cristina Perez, Cirino Botta, Aintzane Zabaleta, Noemi Puig, Maria-Teresa Cedena, Ibai Goicoechea, Daniel Alameda, Edurne San José-Eneriz, Juana Merino, Paula Rodríguez-Otero, Catarina Maia, Diego Alignani, Patricia Maiso, Irene Manrique, David Lara-Astiaso, Amaia Vilas-Zornoza, Sarai Sarvide, Caterina Riillo, Marco Rossi, Laura Rosiñol, Albert Oriol, María-Jesús Blanchard, Rafael Rios, Anna Sureda, Jesus Martin, Rafael Martinez, Joan Bargay, Javier de la Rubia, Miguel-Teodoro Hernandez, Joaquin Martinez-Lopez, Alberto Orfao, Xabier Agirre, Felipe Prosper, Maria-Victoria Mateos, Juan-José Lahuerta, Joan Blade, Jesús F. San-Miguel, Bruno Paiva
Journal: Blood
Blood (2020) 136 (2): 199–209.
https://doi.org/10.1182/blood.2019004537
Published: 2020
Includes: Supplemental data
Journal Articles

Mutational profile and benefit of gemtuzumab ozogamicin in acute myeloid leukemia

Clinical Trials & Observations Brief Report
Elise Fournier, Nicolas Duployez, Benoît Ducourneau, Emmanuel Raffoux, Pascal Turlure, Denis Caillot, Xavier Thomas, Alice Marceau-Renaut, Sylvain Chantepie, Jean-Valère Malfuson, Emilie Lemasle, Meyling Cheok, Karine Celli-Lebras, Estelle Guerin, Christine Terré, Juliette Lambert, Cécile Pautas, Hervé Dombret, Sylvie Castaigne, Claude Preudhomme, Nicolas Boissel
Journal: Blood
Blood (2020) 135 (8): 542–546.
https://doi.org/10.1182/blood.2019003471
Published: 2020
Includes: Supplemental data
Journal Articles

How I treat acute myeloid leukemia in the era of new drugs

Courtney D. DiNardo, Andrew H. Wei
Journal: Blood
Blood (2020) 135 (2): 85–96.
https://doi.org/10.1182/blood.2019001239
Published: 2020
Includes: Supplemental data
Journal Articles

Phase 1 Trial of Cladribine, High-Dose Cytarabine, G-CSF, and Dose-Escalated Mitoxantrone (CLAG-M) Plus Gemtuzumab Ozogamicin in Adults with Newly-Diagnosed Acute Myeloid Leukemia (AML) or Other High-Grade Myeloid Neoplasm

Colin D. Godwin, MDMPhil, Megan Othus, PhD, Mary-Elizabeth M. Percival, MD, Bart L. Scott, MD, Pamela S. Becker, MD PhD, Kelda M. Gardner, PA-C, Sioban B. Keel, MD, Tejaswini M. Dhawale, MD, Vivian G. Oehler, MD, Janis L. Abkowitz, MD, Anna B. Halpern, MD, Paul C. Hendrie, MD PhD, Kaysey F. Orlowski, Alice Woo, Elihu H. Estey, MD, Roland B. Walter, MD PhD MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 3892.
https://doi.org/10.1182/blood-2019-126009
Published: 2019
Journal Articles

Latent Membrane Protein 1 Contributes to Deficient Cellular Immunity in NKTCL Patients

Xiaoyan Feng, Yue Song, Zhaoming Li, MD PhD, Xudong Zhang, Lugui Qiu, MD PhD, Mingzhi Zhang, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3969.
https://doi.org/10.1182/blood-2019-128622
Published: 2019
Journal Articles

BrUOG 345: Fractionated Gemtuzumab Ozogamicin Followed By Non-Engraftment Donor Leukocyte Infusions for Relapsed/Refractory Acute Myeloid Leukemia

Adam Zayac, MD, Pamela C Egan, MD, Thomas A Ollila, MD, Adam J Olszewski, MD, Peter Barth, MD, Matthew I. Quesenberry, MD, James Butera, MD, Loren D. Fast, PhD, Rabin Niroula, MBBS, Peter J. Quesenberry, MD, John L Reagan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4460.
https://doi.org/10.1182/blood-2019-123789
Published: 2019
Journal Articles

CRISPR/Cas9-Mediated Protection of Normal Hematopoiesis Combined with the CD33/CD3 Bispecific T-Cell Engager (BiTE) Antibody AMG330 for Improved AML Therapy

Olivier Humbert, PhD, Mallory J Llewellyn, George S. Laszlo, PhD, Roland B. Walter, MD PhD MS, Hans-Peter Kiem, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4427.
https://doi.org/10.1182/blood-2019-129399
Published: 2019
Journal Articles

Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in AML

Sagarajit Mohanty, MSc, Nidhi Jyotsana, PhD, Amit Sharma, PhD, Basem Othman, Arnold Kloos, PhD, Madhvi Mandhania, MSc, Renate Schottmann, Euan Ramsay, PhD, Hans- Peter Vornlocher, PhD, Arnold Ganser, MD, Felicitas Thol, MD, Michael Heuser, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2545.
https://doi.org/10.1182/blood-2019-123709
Published: 2019
Journal Articles

Preclinical Assessment of Non-Virally Engineered CD33.CAR Cytokine-Induced Killer (CIK) Cells in Chemoresistant AML Patient-Derived Xenografts

Maria Caterina Rotiroti, PhD, Chiara Buracchi, PhD, Silvia Arcangeli, PhD, Chiara F Magnani, PhD, Claudia Cappuzzello, PhD, Zsuzsanna Izsvak, PhD, Stefania Galimberti, PhD, Maria Grazia Valsecchi, PhD, Giuseppe Dastoli, MD, Marta Serafini, PhD, Ettore Biagi, MD, Andrea Biondi, MD, Sarah Tettamanti, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2665.
https://doi.org/10.1182/blood-2019-130399
Published: 2019
Journal Articles

Investigation of Homing Capacity As Prognostic Marker in Human Acute Myeloid Leukemia

Pauline Hanns, MSc, Marcelle Baer, MSc, Anna M Paczulla, PhD, Martina Konantz, PhD, Claudia Lengerke, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2701.
https://doi.org/10.1182/blood-2019-127647
Published: 2019
Journal Articles

Preclinical Characterization of Prgn-3006 Ultracar-T™ for the Treatment of AML and MDS: Non-Viral, Multigenic Autologous CAR-T Cells Administered One Day after Gene Transfer

Tim Chan, PhD, Xiaohong Ma, Fernando Carvajal-Borda, DVM, Jose Velez, Jacques Plummer, Lindsey Shepard, Rutul R Shah, David A Sallman, MD, Helen Sabzevari, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2660.
https://doi.org/10.1182/blood-2019-130617
Published: 2019
Journal Articles

Lintuzumab Ac-225 in Combination with CLAG-M Chemotherapy in Relapsed/Refractory AML: Interim Results of a Phase I Study

Sameem Abedin, MD, Guru Subramanian Guru Murthy, MBBS, Lyndsey Runaas, MD, Laura C. Michaelis, MD, Ehab L. Atallah, MD, Mehdi Hamadani, MD, Alexandra M. Harrington, MDMT(ASCP), Karen Carlson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2605.
https://doi.org/10.1182/blood-2019-122487
Published: 2019
Journal Articles

Poor-Risk AML with Complex, Monosomal Karyotype: In Vivo Therapeutic Efficacy of Decitabine (DAC) in Patient-Derived Xenograft (PDX) Mouse Models

Gabriele Greve, PhD, Julia Schüler, DVM, Eva Oswald, PhD, Michael Lübbert
Journal: Blood
Blood (2019) 134 (Supplement_1): 2644.
https://doi.org/10.1182/blood-2019-126514
Published: 2019
Journal Articles

Liposomal Cytarabine and Daunorubicin (CPX-351) in Combination with Gemtuzumab Ozogamicin (GO) in Relapsed Refractory (R/R) Patients with Acute Myeloid Leukemia (AML) and Post-Hypomethylating Agent (Post-HMA) Failure High-Risk Myelodysplastic Syndrome (HR-MDS)

Jorge M. Ramos Perez, Tapan M. Kadia, MD, Guillermo Montalban-Bravo, MD, Christopher B. Benton, MD, Stefan Faderl, Koji Sasaki, MD, Kiran Naqvi, MDMPH, Jorge E. Cortes, MD, Naval G. Daver, MD, Courtney D. DiNardo, MDMSc, Elias Jabbour, MD, Gautam M. Borthakur, MD, Hind Al Azzawi, Naveen Pemmaraju, MD, Marina Y Konopleva, MD PhD, Sherry A. Pierce, BSN, BA, Nitin Jain, MD, Maro Ohanian, DO, Guillermo Garcia-Manero, MD, Michael Andreeff, MD PhD, Hagop M. Kantarjian, MD, Farhad Ravandi, MD, Yesid Alvarado, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2642.
https://doi.org/10.1182/blood-2019-129137
Published: 2019
Journal Articles

Anti-Apoptotic BCL-2 Family Members Confer Resistance to Calicheamicin-Based Antibody-Drug Conjugate Therapy of Acute Leukemia

Colin D. Godwin, MDMPhil, Olivia M. Bates, BA, Sae Rin Jean, PhD, George S. Laszlo, PhD, Eliotte E. Garling, BA, Mary E. Beddoe, BS, Michael H. Cardone, PhD, Roland B. Walter, MD PhD MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2561.
https://doi.org/10.1182/blood-2019-126110
Published: 2019
Journal Articles

Redirecting T-Cells Against AML in a Multidimensional Targeting Space Using T-Cell Engaging Antibody Circuits (TEAC)

Eleanor Minogue, BSc, David Millar, PhD, Yan Chuan, PhD, Songfa Zhang, MD PhD, Korneel Grauwet, PhD, Mei Guo, Adam Langenbucher, Cyril H Benes, James Heather, PhD, Jeremy Minshull, PhD, Michael S. Lawrence, PhD, Rupa Narayan, David M. Langenau, PhD, Timothy A. Graubert, MD, Mark Cobbold
Journal: Blood
Blood (2019) 134 (Supplement_1): 2653.
https://doi.org/10.1182/blood-2019-127634
Published: 2019
Journal Articles

Defining the Differentiation States of Multiple Myeloma at Single Cell Resolution Reveals Opportunities for Immunotherapy

Julia Frede, PhD MPhil, Praveen Anand, PhD, Andrew J. Yee, MD, Tushara Vijaykumar, Monica S. Nair, Johannes M. Waldschmidt, MD, Sayalee V. Potdar, Jake A. Kloeber, Antonis Kokkalis, PhD MSc, Guangwu Guo, PhD, Samantha J. Shapiro, Mason L. Mann, Robb S Friedman, MD, Brea C. Lipe, MD, Erica L. Campagnaro, MD, Craig E. Cole, MD, Elizabeth K. O'Donnell, MD, Thomas Guerrero, MD, Omar Nadeem, MD, Jacob P. Laubach, MD, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Noopur Raje, MD, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3091.
https://doi.org/10.1182/blood-2019-130247
Published: 2019