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Journal Articles

Immunological Footprints of Pediatric Acute Myeloid Leukemia in Local Bone Marrow T Cells

Paula Rothämel, Semjon Willier, Jonas Wilhelm, Fiona AG Becker-Dettling, Theresa Kaeuferle, Franziska Blaeschke, Meino Rohlfs, Irene Schmid, Vera Binder, Christoph Klein, Thomas Walzthoeni, Matthias Heinig, Tobias Feuchtinger
Journal: Blood
Blood (2023) 142 (Supplement 1): 1587.
https://doi.org/10.1182/blood-2023-188947
Published: 2023
Journal Articles

Human genetic defects in SRP19 and SRPRA cause severe congenital neutropenia with distinctive proteome changes

Monika I. Linder, Yoko Mizoguchi, Sebastian Hesse, Gergely Csaba, Megumi Tatematsu, Marcin Łyszkiewicz, Natalia Ziȩtara, Tim Jeske, Maximilian Hastreiter, Meino Rohlfs, Yanshan Liu, Piotr Grabowski, Kaarin Ahomaa, Daniela Maier-Begandt, Marko Schwestka, Vahid Pazhakh, Abdulsalam I. Isiaku, Brenda Briones Miranda, Piers Blombery, Megumu K. Saito, Ejona Rusha, Zahra Alizadeh, Zahra Pourpak, Masao Kobayashi, Nima Rezaei, Ekrem Unal, Fabian Hauck, Micha Drukker, Barbara Walzog, Juri Rappsilber, Ralf Zimmer, Graham J. Lieschke, Christoph Klein
Journal: Blood
Blood (2023) 141 (6): 645–658.
https://doi.org/10.1182/blood.2022016783
Published: 2023
Includes: Supplemental data
Journal Articles

CLEC12A and CD33 coexpression as a preferential target for pediatric AML combinatorial immunotherapy

Semjon Willier, Paula Rothämel, Maximilian Hastreiter, Jonas Wilhelm, Dana Stenger, Franziska Blaeschke, Meino Rohlfs, Theresa Kaeuferle, Irene Schmid, Michael H. Albert, Vera Binder, Marion Subklewe, Christoph Klein, Tobias Feuchtinger
Journal: Blood
Blood (2021) 137 (8): 1037–1049.
https://doi.org/10.1182/blood.2020006921
Published: 2021
Includes: Supplemental data
Journal Articles

Novel Immune Checkpoint Deficiency and Susceptibility to EBV-Associated Lymphoma

Ido Somekh, Thomas Magg, PhD, Alejandro Gallón Duque, Tali Stauber, MD, Atar Lev, MSc, Ekrem Unal, MD, Amos J. Simon, PhD, Meino Rohlfs, PhD, Raffaele Conca, MSc, Megumi Tatematsu, PhD, Fabian Hauck, MD PhD, Raz Somech, MD PhD, Christoph Klein, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2326.
https://doi.org/10.1182/blood-2019-128296
Published: 2019
Journal Articles

CD137 deficiency causes immune dysregulation with predisposition to lymphomagenesis

Brief Report
Ido Somekh, Marini Thian, David Medgyesi, Nesrin Gülez, Thomas Magg, Alejandro Gallón Duque, Tali Stauber, Atar Lev, Ferah Genel, Ekrem Unal, Amos J. Simon, Yu Nee Lee, Artem Kalinichenko, Jasmin Dmytrus, Michael J. Kraakman, Ginette Schiby, Meino Rohlfs, Jeffrey M. Jacobson, Erdener Özer, Ömer Akcal, Raffaele Conca, Türkan Patiroglu, Musa Karakukcu, Alper Ozcan, Tala Shahin, Eliana Appella, Megumi Tatematsu, Catalina Martinez-Jaramillo, Ivan K. Chinn, Jordan S. Orange, Claudia Milena Trujillo-Vargas, José Luis Franco, Fabian Hauck, Raz Somech, Christoph Klein, Kaan Boztug
Journal: Blood
Blood (2019) 134 (18): 1510–1516.
https://doi.org/10.1182/blood.2019000644
Published: 2019
Includes: Supplemental data
Journal Articles

Bone Marrow T Cells Are Driven into Exhaustion By Acute Leukemia in Pediatric Patients Based on Protein and Transcriptome Analysis

Semjon Willier, MD, Paula Rothaemel, Jonas Wilhelm, Dana Stenger, Theresa Kaeuferle, PhD, Irene Schmid, MD, Michael H. Albert, MD, Vera Binder, MD, Meino Rohlfs, PhD, Sebastian Hollizeck, Christoph Klein, MD PhD, Franziska Blaeschke, MD, Tobias Feuchtinger, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3722.
https://doi.org/10.1182/blood-2018-99-112811
Published: 2018
Journal Articles

TIM-3 Expression on CD4 + Bone Marrow T Cells Predicts Relapse of Pediatric B-Precursor Acute Lymphoblastic Leukemia

Franziska Blaeschke, MD, Semjon Willier, MD, Dana Stenger, Mareike Lepenies, Martin A. Horstmann, MD, Gabriele Escherich, Martin Zimmermann, PhD, Theresa Kaeuferle, PhD, Meino Rohlfs, PhD, Irene Schmid, MD, Michael H. Albert, MD, Vera Binder, MD, Christoph Klein, MD PhD, Tobias Feuchtinger, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2833.
https://doi.org/10.1182/blood-2018-99-118376
Published: 2018
Journal Articles

Novel Mutations in RASGRP1 Are Associated with Immune Dysregulation and Predispose to EBV-Induced Lymphoma

Ido Somekh, MD, Benjamin Marquardt, MSc, Yanshan Liu, PhD, Meino Rohlfs, PhD, Shirly Frizinsky, MD, Ekrem Unal, MD, Daniel Kotlarz, MD PhD, Raz Somech, MD PhD, Christoph Klein, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2287.
https://doi.org/10.1182/blood.V130.Suppl_1.2287.2287
Published: 2017
Journal Articles

Rltpr Is a Central Scaffold Protein Regulating Human TCR Co-Signaling and Cytoskeletal Dynamics

Tilmann Schober, MD, Thomas Magg, PhD, Melanie Laschinger, PhD, Thomas Fröhlich, PhD, Meino Rohlfs, PhD, Yanshan Liu, PhD, Jacek Puchalka, PhD, Tanja Weisser, Karin Fehlner, PhD, Christoph Walz, MD, Natália Duarte Linhares, PhD, Sérgio D. Pena, MD PhD, Bernd H. Belohradsky, MD, Christoph Klein, MD PhD, Fabian Hauck, MD PhD
Journal: Blood
Blood (2016) 128 (22): 131.
https://doi.org/10.1182/blood.V128.22.131.131
Published: 2016
Journal Articles

SWI/SNF Protein SMARCD2 Orchestrates Transcriptional Networks Controlling Hematopoiesis and Neutrophil Granulocytes in Humans, Mice and Zebrafish

Maximilian Witzel, MD, Daniel Petersheim, Yanxin Fan, MSc, Ehsan Bahrami, MSc, Tomas Racek, PhD, Meino Rohlfs, PhD, Jacek Puchalka, PhD, Christian Mertes, MSc, Julien Gagneur, PhD, Christoph Ziegenhain, MSc, Wolfgang Enard, PhD, Asbjorg Stray-Pedersen, MD PhD, Peter D Arkwright, MD, Miguel R Abboud, MD, Vahid Pazhakh, MSc, Graham J Lieschke, PhD MBBS, BMedSc, FRACP, Peter K Krawitz, MD, Maik Dahlhoff, DVM, Marlon R Schneider, DVM, Eckhard Wolf, DVM, Hans-Peter Horny, MD, Heinrich Schmidt, MD, Alejandro A Schäffer, PhD, Christoph Klein, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2.
https://doi.org/10.1182/blood.V128.22.2.2
Published: 2016