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Seiya Imoto
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Journal Articles

Installment of Automation and Modernized Culture Methods Updates a Drug-Sensitivity Screening Platform and Paves the Way to Next-Generation of Precision Medicine

Kimihito Cojin Kawabata, Chao Li, Hideaki Kakinuma, Yoshiharu Takama, Hayato Tsuji, Hironobu Komori, Bo Gong, Yasumasa Kimura, Hideki Tanomura, Atsushi Okamoto, Maiko Morita, Hiroyuki Takamori, Hidehito Fukushima, Kazuaki Yokoyama, Takaaki Konuma, Nobuhiro Ohno, Susumu Goyama, Satoshi Yamazaki, Tetsushi Oka, Gen Kudo, Ari M Melnick, Yasuhito Nannya, Seiya Imoto, Satoshi Takahashi
Journal: Blood
Blood (2024) 144 (Supplement 1): 7475.
https://doi.org/10.1182/blood-2024-199921
Published: 2024
Journal Articles

Whole-Genome Sequencing of 95 Japanese Patients with Pediatric Acute Myeloid Leukemia

Kaito Mimura, Norio Shiba, Ai Okada, Kenichi Chiba, Kentaro Watanabe, Takao Deguchi, Kentaro Ohki, Kotoe Katayama, Seiya Imoto, Akiko M Saito, Yasuhiro Okamoto, Souichi Adachi, Daisuke Tomizawa, Takashi Taga, Yuichi Shiraishi, Hiroshi Moritake, Motohiro Kato, Kenichi Yoshida
Journal: Blood
Blood (2024) 144 (Supplement 1): 5720.
https://doi.org/10.1182/blood-2024-200476
Published: 2024
Journal Articles

Genetic Profile of Myeloid Neoplasms Developed with Fanconi Anemia and Aldehyde Degradation Deficiency Syndrome

Mayu Morishita, Miharu Yabe, Nobuyuki Kakiuchi, Minoru Takata, Kotoe Katayama, Seiya Imoto, Seishi Ogawa, Hiromasa Yabe, Kenichi Yoshida
Journal: Blood
Blood (2023) 142 (Supplement 1): 2738.
https://doi.org/10.1182/blood-2023-184552
Published: 2023
Journal Articles

Clonal Hematopoiesis Is Associated with Severe COVID-19 Enhancing Inflammatory Responses in Myeloid Cells

Ryunosuke Saiki, Ryuya Edahiro, Kyuto Sonehara, Qingbo S Wang, Ho Namkoong, Takanori Hasegawa, Hiromu Tanaka, Shuhei Azekawa, Shotaro Chubachi, Shinichi Namba, Kenichi Yamamoto, Nobuyuki Kakiuchi, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Hideki Makishima, Yasuhito Nannya, Ryuji Koike, Tomomi Takano, Makoto Ishii, Akinori Kimura, Seiya Imoto, Satoru Miyano, Takanori Kanai, Koichi Fukunaga, Yukinori Okada, Seishi Ogawa
Journal: Blood
Blood (2023) 142 (Supplement 1): 1321.
https://doi.org/10.1182/blood-2023-181354
Published: 2023
Journal Articles

Transposable Elements Are Differentially Expressed in MDS Stem Cells in a Disease-Stage-Specific Manner

Shuhei Kurosawa, Motohiko Oshima, Yaeko Nakajima-Takagi, Naoya Takayama, Daisuke Shinoda, Satoshi Kaito, Takahiro Kamiya, Yuta Yamada, Shohei Andoh, Kensuke Kayamori, Emiko Sakaida, Eriko Sato, Nozomi Yusa, Kazuaki Yokoyama, Yasuhito Nannya, Arinobu Tojo, Seiya Imoto, Bahityar Rahmutulla, Atsushi Kaneda, Kiyoshi Yamaguchi, Yoichi Furukawa, Noriko Doki, Kei Nishikawa, Ye Ding, Tomohiro Myojo, Yuka Harada, Hironori Harada, Atsushi Iwama
Journal: Blood
Blood (2023) 142 (Supplement 1): 6458.
https://doi.org/10.1182/blood-2023-172607
Published: 2023
Journal Articles

Detailed Analysis of the Impact of Clonal Hematopoiesis on the Risk of Severe COVID-19 Infection

Ryunosuke Saiki, Ho Namkoong, Ryuya Edahiro, Kyuto Sonehara, Qingbo S Wang, Takanori Hasegawa, Yukihide Momozawa, Hideki Makishima, Yasuhito Nannya, Nobuyuki Kakiuchi, Chikashi Terao, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Koichi Matsuda, Takayuki Morisaki, Yoshinori Murakami, Yoichiro Kamatani, Michiaki Kubo, Akinori Kimura, Seiya Imoto, Satoru Miyano, Takanori Kanai, Koich Fukunaga, Yukinori Okada, Seishi Ogawa
Journal: Blood
Blood (2022) 140 (Supplement 1): 5747–5748.
https://doi.org/10.1182/blood-2022-160436
Published: 2022
Journal Articles

Genomic Analysis of Therapy-Related Myeloid Neoplasms and Tracking of the Founder Clone By Circulating Tumor DNA

Kanya Kondoh, MD, Kazuaki Yokoyama, MD PhD, Nozomi Yusa, Mika Ito, Eigo Shimizu, Sousuke Nakamura, MD, Miho Ogawa, MD, Tomomi Takei, MD, Asako Kobayashi, Rika Kasajima, PhD, Yuka Wada, Rui Yamaguchi, PhD, Seiya Imoto, PhD, Tokiko Nagamura-Inoue, MD PhD, Kaoru Uchimaru, MD, PhD, Satoru Miyano, PhD, Arinobu Tojo, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5393.
https://doi.org/10.1182/blood-2019-127611
Published: 2019
Journal Articles

Prognostic impact of circulating tumor DNA status post–allogeneic hematopoietic stem cell transplantation in AML and MDS

Clinical Trials & Observations
Sousuke Nakamura, Kazuaki Yokoyama, Eigo Shimizu, Nozomi Yusa, Kanya Kondoh, Miho Ogawa, Tomomi Takei, Asako Kobayashi, Mika Ito, Masamichi Isobe, Takaaki Konuma, Seiko Kato, Rika Kasajima, Yuka Wada, Tokiko Nagamura-Inoue, Rui Yamaguchi, Satoshi Takahashi, Seiya Imoto, Satoru Miyano, Arinobu Tojo
Journal: Blood
Blood (2019) 133 (25): 2682–2695.
https://doi.org/10.1182/blood-2018-10-880690
Published: 2019
Includes: Supplemental data
Journal Articles

Prognostic Impact of Circulating Tumor DNA Status Post-Allogeneic Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia and Myelodysplastic Syndrome

Sousuke Nakamura, MD, Kazuaki Yokoyama, MD PhD, Eigo Shimizu, Nozomi Yusa, Miho Ogawa, MD, Tomomi Takei, MD, Asako Kobayashi, Mika Ito, Masamichi Isobe, MD PhD, Takaaki Konuma, MD PhD, Seiko Kato, MD PhD, Rika Kasajima, PhD, Yuka Wada, Tokiko Nagamura-Inoue, MDPhD, Rui Yamaguchi, PhD, Satoshi Takahashi, MD PhD, Seiya Imoto, PhD, Satoru Miyano, PhD, Arinobu Tojo, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 247.
https://doi.org/10.1182/blood-2018-99-117938
Published: 2018
Journal Articles

Artificial Intelligence Guided Precision Medicine Approach to Hematological Disease

Tomomi Takei, MD, Kazuaki Yokoyama, MD PhD, Nozomi Yusa, Sousuke Nakamura, MD, Miho Ogawa, MD, Kanya Kondoh, MD, Masayuki Kobayashi, MD, Asako Kobayashi, Mika Ito, Eigo Shimizu, Mako Yamamoto, Rika Kasajima, PhD, Koichiro Yuji, MD PhD, Rui Yamaguchi, PhD, Yoichi Furukawa, MD PhD, Seiya Imoto, PhD, Satoru Miyano, PhD, Arinobu Tojo, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2254.
https://doi.org/10.1182/blood-2018-99-117941
Published: 2018
Journal Articles

Personalized Circulating Tumor DNA Dynamically Predicts Response and/or Relapse in Hematological Malignancies

Sousuke Nakamura, MD, Kazuaki Yokoyama, MD PhD, Nozomi Yusa, Miho Ogawa, MD, Tomomi Takei, MD, Asako Kobayashi, Mika Ito, Masayuki Kobayashi, MD, Eigo Shimizu, Rika Kasajima, PhD, Yuka Wada, Rui Yamaguchi, PhD, Seiya Imoto, PhD, Yoichi Furukawa, MD PhD, Tokiko Nagamura-Inoue, MDPhD, Satoru Miyano, PhD, Arinobu Tojo, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1406.
https://doi.org/10.1182/blood.V130.Suppl_1.1406.1406
Published: 2017
Journal Articles

A Novel Mutant Wasp in X-Linked Neutropenia Partially Recapitulates Defective Neutrophil Production through Its Expression in WASP-Deficient NB4 Cells

Masayuki Kobayashi, MD, Bidisha Chanda, MD PhD, Muneyoshi Futami, MD PhD, Mizuho Yamashita, Mitsuhito Hirano, MD, Kazuaki Yokoyama, MD PhD, Yoichi Imai, MDPhD, Eigo Shimizu, Nozomi Yusa, Rui Yamaguchi, PhD, Seiya Imoto, PhD, Satoru Miyano, PhD, Arinobu Tojo, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3560.
https://doi.org/10.1182/blood.V130.Suppl_1.3560.3560
Published: 2017
Journal Articles

Personalized Circulating Tumor DNA Predicts Relapse after Allogeneic Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia and Myelodysplastic Syndrome

Sousuke Nakamura, MD, Kazuaki Yokoyama, MD PhD, Nozomi Yusa, Miho Ogawa, MD, Tomomi Takei, MD, Asako Kobayashi, Mika Ito, Masayuki Kobayashi, MD, Koji Jimbo, MD, Susumu Tanoue, MD, Masamichi Isobe, MD PhD, Takaaki Konuma, MD PhD, Seiko Kato, MD PhD, Eigo Shimizu, Rika Kasajima, PhD, Yuka Wada, Rui Yamaguchi, PhD, Seiya Imoto, PhD, Yoichi Furukawa, MD PhD, Tokiko Nagamura-Inoue, MDPhD, Satoshi Takahashi, MD PhD, Satoru Miyano, PhD, Arinobu Tojo, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3268.
https://doi.org/10.1182/blood.V130.Suppl_1.3268.3268
Published: 2017
Journal Articles

Exploratory Introduction of Cognitive Computing to Clinical Sequencing in Hematological Malignancies

Kazuaki Yokoyama, MD PhD, Nozomi Yusa, Mika Itoh, Asako Suzuki, Sosuke Nakamura, Miho Ogawa, Koji Jimbo, Masayuki Kobayashi, Toyotaka Kawamata, Takaaki Konuma, Rika Kasajima, Hiroaki Yui, Eigo Shimizu, Takahiko Koyama, Nobuhiro Ohno, Yoichi Imai, Satoshi Takahashi, Kaoru Uchimaru, Rui Yamaguchi, Seiya Imoto, Yoichi Furukawa, Satoru Miyano, Arinobu Tojo
Journal: Blood
Blood (2016) 128 (22): 5262.
https://doi.org/10.1182/blood.V128.22.5262.5262
Published: 2016