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Tomohiko Tamura
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Journal Articles

Cbl Q367P Cooperates with Loss of Tet2 to Drive a Cnl-like Disease Via the NF-Kb Pathway

Takuma Ohashi, Hiroyoshi Kunimoto, Akiko Adachi, Ayaka Miura, Takayuki Sakuma, Junji Ikeda, Yoko Ino, Jotaro Harada, Yuko Shimosato, Keita Yamamoto, Yayoi Kimura, Susumu Goyama, Satoshi Fujii, Tomohiko Tamura, Hiroaki Honda, Sheng F. Cai, Hideaki Nakajima
Journal: Blood
Blood (2024) 144 (Supplement 1): 4515.
https://doi.org/10.1182/blood-2024-206175
Published: 2024
Journal Articles

Metabolic Reprogramming By PRDM16 Drives Cytarabine Resistance in Acute Myeloid Leukemia

Junji Ikeda, Hiroyoshi Kunimoto, Yusuke Saito, Shin-Ichi Tsujimoto, Takayuki Kurosawa, Masanobu Takeuchi, Ayaka Miura, Koichi Murakami, Ikuma Kato, Takako Hishiki, Noriyo Hayakawa, Tomomi Matsuura, Megumi Funakoshi-Tago, Akihiko Yokoyama, Kenichi Yoshida, Daisuke Tomizawa, Satoru Miyano, Akio Tawa, Souichi Adachi, Seishi Ogawa, Yasuhide Hayashi, Norio Shiba, Tomohiko Tamura, Shuichi Ito, Hideaki Nakajima
Journal: Blood
Blood (2023) 142 (Supplement 1): 2740.
https://doi.org/10.1182/blood-2023-181740
Published: 2023
Journal Articles

Dysfunctional Clusterin-Positive Hematopoietic Stem Cells Expand with Aging

Shuhei Koide, Motohiko Oshima, Akira Nishiyama, Koichi Murakami, Naoki Itokawa, Yaeko Nakajima-Takagi, Zhiqian Zheng, Nozomi Yusa, Kazuaki Yokoyama, Arinobu Tojo, Tomohiko Tamura, Atsushi Iwama
Journal: Blood
Blood (2022) 140 (Supplement 1): 2225–2226.
https://doi.org/10.1182/blood-2022-165787
Published: 2022
Journal Articles

Unraveling Heterogeneity of Aged Hematopoietic Stem Cells By Single-Cell RNA Sequence Analysis

Shuhei Koide, Motohiko Oshima, Akira Nishiyama, Koichi Murakami, Yuta Yamada, Naoki Itokawa, Yaeko Nakajima-Takagi, Zhiqian Zheng, Tomohiko Tamura, Atsushi Iwama
Journal: Blood
Blood (2021) 138 (Supplement 1): 4299.
https://doi.org/10.1182/blood-2021-149876
Published: 2021
Journal Articles

Epigenetic control of early dendritic cell lineage specification by the transcription factor IRF8 in mice

Daisuke Kurotaki, Wataru Kawase, Haruka Sasaki, Jun Nakabayashi, Akira Nishiyama, Herbert C. Morse, III, Keiko Ozato, Yutaka Suzuki, Tomohiko Tamura
Journal: Blood
Blood (2019) 133 (17): 1803–1813.
https://doi.org/10.1182/blood-2018-06-857789
Published: 2019
Includes: Supplemental data
Journal Articles

Regulation of Mitophagy By O -Linked N -Acetylglucosamine Transferase Is Essential for Hematopoietic Stem Cell Maintenance

Koichi Murakami, MD, Daisuke Kurotaki, PhD, Wataru Kawase, Graduate student, Shunsuke Soma, MD, Yumi Fukuchi, PhD, Hiroyoshi Kunimoto, MD PhD, Ryusuke Yoshimi, MD PhD, Shuhei Koide, PhD, Motohiko Oshima, PhD, Takako Hishiki, PhD, Noriyo Hayakawa, PhD, Tomomi Matsuura, PhD, Minoru Ko, MD PhD, Mayumi Oda, PhD, Kiichi Yanagisawa, Student, Hiroshi Kobayashi, MD PhD, Yoshitoshi Atobe, PhD, Kengo Funakoshi, MD PhD, Atsushi Iwama, MD PhD, Keiyo Takubo, MD PhD, Shinichiro Okamoto, MD PhD, Tomohiko Tamura, MD PhD, Hideaki Nakajima, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 171.
https://doi.org/10.1182/blood-2018-171
Published: 2018
Journal Articles

Enhancer Landscape Dynamics and the Role of IRF8 in Mononuclear Phagocyte Development

Daisuke Kurotaki, PhD, Jun Nakabayashi, MD, PhD, Akira Nishiyama, PhD, Haruka Sasaki, Naofumi Kaneko, Shin-ichi Koizumi, PhD, Keiko Ozato, PhD, Yutaka Suzuki, PhD, Tomohiko Tamura, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 2384.
https://doi.org/10.1182/blood.V126.23.2384.2384
Published: 2015
Journal Articles

Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells

Haruka Sasaki, Daisuke Kurotaki, Naoki Osato, Hideaki Sato, Izumi Sasaki, Shin-ichi Koizumi, Hongsheng Wang, Chika Kaneda, Akira Nishiyama, Tsuneyasu Kaisho, Hiroyuki Aburatani, Herbert C. Morse, III, Keiko Ozato, Tomohiko Tamura
Journal: Blood
Blood (2015) 125 (2): 358–369.
https://doi.org/10.1182/blood-2014-02-557983
Published: 2015
Includes: Supplemental data
Journal Articles

IRF8 Restrains Monocyte-Dendritic Cell Progenitors from Differentiating into Neutrophils by Inhibiting C/EBPα Activity

Daisuke Kurotaki, PhD, Michio Yamamoto, Akira Nishiyama, PhD, Kazuhiro Uno, Haruka Sasaki, Keiko Ozato, PhD, Tomohiko Tamura, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2438.
https://doi.org/10.1182/blood.V122.21.2438.2438
Published: 2013
Journal Articles

The Transcription Factor IRF8 is a Key Transcription Factor for Basophil Development

Daisuke Kurotaki, PhD, Haruka Sasaki, Naoki Osato, PhD, Izumi Sasaki, PhD, Chika Kaneda, Hideaki Sato, Akira Nishiyama, PhD, Tsuneyasu Kaisho, MD, PhD, Hiroyuki Aburatani, M.D., Ph.D., Herbert C. Morse, III, MD, Keiko Ozato, PhD, Tomohiko Tamura, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1197.
https://doi.org/10.1182/blood.V122.21.1197.1197
Published: 2013
Journal Articles

Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation

Daisuke Kurotaki, Naoki Osato, Akira Nishiyama, Michio Yamamoto, Tatsuma Ban, Hideaki Sato, Jun Nakabayashi, Marina Umehara, Noriko Miyake, Naomichi Matsumoto, Masatoshi Nakazawa, Keiko Ozato, Tomohiko Tamura
Journal: Blood
Blood (2013) 121 (10): 1839–1849.
https://doi.org/10.1182/blood-2012-06-437863
Published: 2013
Includes: Supplemental data
Journal Articles

The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse

Brief Report
Prafullakumar Tailor, Tomohiko Tamura, Herbert C. Morse, III, Keiko Ozato
Journal: Blood
Blood (2008) 111 (4): 1942–1945.
https://doi.org/10.1182/blood-2007-07-100750
Published: 2008
Includes: Supplemental data
Journal Articles

Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages

Tomohiko Tamura, Pratima Thotakura, Tetsuya S. Tanaka, Minoru S. H. Ko, Keiko Ozato
Journal: Blood
Blood (2005) 106 (6): 1938–1947.
https://doi.org/10.1182/blood-2005-01-0080
Published: 2005
Includes: Supplemental data
Journal Articles

The interferon regulatory factor ICSBP/IRF-8 in combination with PU.1 up-regulates expression of tumor suppressor p15 Ink4b in murine myeloid cells

Martina Schmidt, Juraj Bies, Tomohiko Tamura, Keiko Ozato, Linda Wolff
Journal: Blood
Blood (2004) 103 (11): 4142–4149.
https://doi.org/10.1182/blood-2003-01-0285
Published: 2004
Journal Articles

ICSBP/IRF-8 inhibits mitogenic activity of p210 Bcr/Abl in differentiating myeloid progenitor cells

Tomohiko Tamura, Hee Jeong Kong, Chainarong Tunyaplin, Hideki Tsujimura, Kathryn Calame, Keiko Ozato
Journal: Blood
Blood (2003) 102 (13): 4547–4554.
https://doi.org/10.1182/blood-2003-01-0291
Published: 2003
Journal Articles

ICSBP/IRF-8 retrovirus transduction rescues dendritic cell development in vitro

Hideki Tsujimura, Tomohiko Tamura, Celine Gongora, Julio Aliberti, Caetano Reis e Sousa, Alan Sher, Keiko Ozato
Journal: Blood
Blood (2003) 101 (3): 961–969.
https://doi.org/10.1182/blood-2002-05-1327
Published: 2003
Journal Articles

Vitamin A deficiency in mice causes a systemic expansion of myeloid cells

Takeshi Kuwata, I-Ming Wang, Tomohiko Tamura, Roshini M. Ponnamperuma, Rachel Levine, Kevin L. Holmes, Herbert C. Morse, III, Luigi M. De Luca, Keiko Ozato
Journal: Blood
Blood (2000) 95 (11): 3349–3356.
https://doi.org/10.1182/blood.V95.11.3349
Published: 2000