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Journal Articles

Role of Autoantigen Induced-B-Cell Receptor Internalization and Its Inhibition for the Biology and Survival of Diffuse Large B-Cell Lymphoma (DLBCL) Cells

Patryk Gorniak, Ondrej Havránek, Anna Polak, Przemyslaw Juszczynski

Blood (2023) 142 (Supplement 1): 4141.

https://doi.org/10.1182/blood-2023-187046

Published: 2023

Journal Articles

Epigenetic and Transcriptional Consequences of PIM Kinase Activity and Inhibition in Diffuse Large B-Cell Lymphoma (DLBCL)

Sonia Debek, Dorota Komar, Filip Garbicz, Aleksandra Zolyniak, Michal Pawlak, Ewa Jablonska, Maciej Szydlowski, Magdalena Skrzypczak, Sylwia Radomska, Małgorzata Bajor, Nazli Serin, Bjoern Chapuy, Przemysław Juszczyński

Blood (2023) 142 (Supplement 1): 5713.

https://doi.org/10.1182/blood-2023-189958

Published: 2023

Journal Articles

Raman Spectroscopy Imaging in Evaluation of Immune Cells Activation Status

Paulina Laskowska, Aleksandra Borek-Dorosz, Anna Maria Nowakowska, Aleksandra Zolyniak, Ewa Kurtz, Maciej Szydlowski, Przemysław Juszczyński, Malgorzata Baranska, Katarzyna Majzner, Piotr Mrówka

Blood (2023) 142 (Supplement 1): 7157.

https://doi.org/10.1182/blood-2023-190418

Published: 2023

Journal Articles

Label-Free Identification of Biochemical Footprints of Key Mutations in Acute Myeloid Leukemia Using Raman Spectroscopy

Paulina Laskowska, Sylwia Orzechowska, Aleksandra Borek-Dorosz, Anna Maria Nowakowska, Wiktoria Korona, Adriana Adamczyk, Patrycja Leszczenko, Aleksandra Szlachetka, Małgorzata Zasowska, Maciej Szydlowski, Przemysław Juszczyński, Malgorzata Baranska, Katarzyna Majzner, Piotr Mrówka

Blood (2023) 142 (Supplement 1): 6022.

https://doi.org/10.1182/blood-2023-190220

Published: 2023

Journal Articles

Raman Spectroscopy Imaging As a Tool to Classify Diffused Large B-Cell Lymphoma Subtypes

Patrycja Dawiec, Paulina Laskowska, Patrycja Leszczenko, Anna Maria Nowakowska, Maciej Szydlowski, Przemysław Juszczyński, Malgorzata Baranska, Katarzyna Majzner, Piotr Mrówka

Blood (2023) 142 (Supplement 1): 5040.

https://doi.org/10.1182/blood-2023-189952

Published: 2023

Journal Articles

Transcriptomic Features Influencing Anti-Myeloma Drug Resistance in Human Multiple Myeloma Cell Lines

Filip Garbicz, Irena Misiewicz-Krzeminska, Ruben D. Carrasco, Przemysław Juszczyński

Blood (2023) 142 (Supplement 1): 1943.

https://doi.org/10.1182/blood-2023-190247

Published: 2023

Journal Articles

Novel Clinically Useful Inhibitor of Mediator Complex, RVU120, Relives Differentiation Block in MDS/AML

Blood (2023) 142 (Supplement 1): 3225.

https://doi.org/10.1182/blood-2023-186227

Published: 2023

Journal Articles

Targeting CDK8/CDK19 to Disrupt Leukemic Stem Cell-like Population in Acute Myeloid Leukemia: Exploring RVU120 As a Promising Frontline Therapy

Milena Mazan, Urszula Pakulska, Adrianna Moszyńska, Agnieszka Sroka-Porada, Krzysztof Tomasz Szade, Michał Mikula, Magdalena Kozakowska, Przemysław Juszczyński, Katarzyna Wiklik, Kristina Göller, Marta Obacz, Camille N. Abboud, Jan Maciej Zaucha, Ewa Lech Marańda, Noemi Angelosanto, Hendrik Nogai, Tomasz Rzymski

Blood (2023) 142 (Supplement 1): 4175.

https://doi.org/10.1182/blood-2023-188866

Published: 2023

Journal Articles

PIM1 Point Mutations Increase Migration of Diffuse Large B-Cell Lymphoma (DLBCL) Cells

Aleksandra Zolyniak, Dorota Komar, Sonia Debek, Filip Garbicz, Michal Pawlak, Przemysław Juszczyński

Blood (2023) 142 (Supplement 1): 2772.

https://doi.org/10.1182/blood-2023-189077

Published: 2023

Journal Articles

Super-Enhancer-Driven PIM Kinase Upregulation in Multiple Myeloma Maintains the Plasma Cell-Specific Oncogenic and Microenvironmental Circuits, and Can be Efficiently Targeted By the Pan-PIM Inhibitor MEN1703

Blood (2022) 140 (Supplement 1): 4189–4190.

https://doi.org/10.1182/blood-2022-168770

Published: 2022

Journal Articles

Multiomics Analysis Confirms Effective Target Engagement for RVU120 - a First-in-Class CDK8/19 Kinase Inhibitor in AML and MR-MDS Patients and Reveals the Mechanism of Action

Blood (2022) 140 (Supplement 1): 5939–5940.

https://doi.org/10.1182/blood-2022-168906

Published: 2022

Journal Articles

PIM Kinases Regulate Super-Enhancer-Dependent Gene Expression in Diffuse Large B-Cell Lymphoma

Sonia Debek, Dorota Komar, Filip Garbicz, Aleksandra Matrejek, Michał Pawlak, Ewa Jabłońska, Maciej Szydlowski, Magdalena Skrzypczak, Sylwia Radomska, Daniela Bellarosa, Nazli Serin, Malgorzata Bajor, Bjoern Chapuy, Przemyslaw Juszczynski

Blood (2022) 140 (Supplement 1): 3044–3045.

https://doi.org/10.1182/blood-2022-167734

Published: 2022

Journal Articles

MEN1703-Mediated PIM Kinases Inhibition Impairs Protumoral and Immunosuppressive Phenotype and Functions of Macrophages in Classical Hodgkin Lymphoma

Maciej Szydlowski, Filip Garbicz, Ewa Kurtz, Justyna Żurańska, Michał Seweryn, Michał Pawlak, Patryk Górniak, Kamil Sokół, Anna Szumera-Ciećkiewicz, Monika Kawecka, Daria Owczarek, Beata Puton, Monika Prochorec-Sobieszek, Daniela Bellarosa, Michał Kurlapski, Jan Zaucha, Paweł Wołkow, Przemyslaw Juszczynski

Blood (2022) 140 (Supplement 1): 6441–6442.

https://doi.org/10.1182/blood-2022-156894

Published: 2022

Journal Articles

CD180 As a Putative Target for Immunotherapy in Aggressive Mature B Cell Lymphomas

Klaudyna Fidyt, Marta Krawczyk, Monika Pepek, Katsiaryna Marhelava, Agnieszka Kraft, Malgorzata Bobrowicz, Aleksandra Kusowska, Joanna Barankiewicz, Przemyslaw Juszczynski, Michal Smida, Myron Czuczman, Francisco Hernandez-Ilizaliturri, Malgorzata Firczuk, Magdalena Winiarska

Blood (2022) 140 (Supplement 1): 10273–10274.

https://doi.org/10.1182/blood-2022-162292

Published: 2022

Journal Articles

Immunoregulatory CD71 + Erythroid Cells (CECs) Expand in Multiple Myeloma and Impair Control of L. Monocytogenes Infection

Tomasz M. Grzywa, Karol Czubak, Karolina Sidor, Zofia Pilch, Aneta Bragiel-Pieczonka, Grazyna Hoser, Anna Rodziewicz-Lurzynska, Milena Małecka-Giełdowska, Joanna Barankiewicz, Filip Garbicz, Olga Ciepiela, Przemyslaw Juszczynski, Michal Wegrzynowicz, Tomasz Skirecki, Jakub Golab, Dominika Nowis

Blood (2022) 140 (Supplement 1): 12538–12539.

https://doi.org/10.1182/blood-2022-164577

Published: 2022

Journal Articles

Preclinical and Clinical Signs of Efficacy of RVU120 (SEL120), a Specific CDK8/19 Inhibitor in DNMT3A-Mutated AML

Blood (2021) 138 (Supplement 1): 2371.

https://doi.org/10.1182/blood-2021-152273

Published: 2021

Journal Articles

RVU120 (SEL120) CDK8/19 Inhibitor - a Drug Candidate for the Treatment of MDS Can Induce Erythroid Differentiation

Blood (2021) 138 (Supplement 1): 1518.

https://doi.org/10.1182/blood-2021-150662

Published: 2021

Journal Articles

Inhibition of PIM Kinases in Diffuse Large B-Cell Lymphoma Cells Targets MYC-Dependent Transcriptional Program, Increases CD20 Expression and Augments the Efficacy of Anti-CD20 Antibodies

Blood (2020) 136 (Supplement 1): 33–34.

https://doi.org/10.1182/blood-2020-134778

Published: 2020

Journal Articles

SIRT1 and HSP90alpha Are Functionally Linked and Control Mitotic Chromosome Segregation and Cell Viability in a Subset of Dlbcls

Emilia Bialopiotrowicz, PhD, Monika Noyszewska-Kania, MSc, Ewa Jabłońska, PhD, Tomasz Sewastianik, PhD, Monika Stańczak, Msc, Anna Szumera-Ciećkiewicz, MD PhD, Katarzyna Borg, PhD, Aleksandra Bluszcz, Msc, Sonia Dębek, MSc, Monika Prochorec-Sobieszek, MD PhD, Anna Polak, PhD, Patryk Górniak, PhD, Maciej Szydlowski, PhD, Przemyslaw Juszczynski, MD PhD

Blood (2020) 136 (Supplement 1): 28–29.

https://doi.org/10.1182/blood-2020-139319

Published: 2020

Journal Articles

Hodgkin Lymphoma Reed-Sternberg Cells Induce Immunosuppressive and Pro-Angiogenic Phenotype of Tumor-Associated Macrophages in a Paracrine Manner

Maciej Szydlowski, PhD, Michał Pawlak, PhD, Filip Garbicz, MD, Patryk Górniak, PhD, Justyna Żurańska, PhD, Magdalena Król, PhD, Bartłomiej Taciak, Maciej Białasek, Anna Szumera-Ciećkiewicz, MD PhD, Kamil Sokół, Monika Stańczak, Msc, Daria Owczarek, Monika Prochorec-Sobieszek, MD PhD, Anna Polak, PhD, Emilia Bialopiotrowicz, PhD, Michał Kurlapski, Jan Zaucha, MDPhD, Paweł Wołkow, PhD, Przemyslaw Juszczynski, MD PhD

Blood (2020) 136 (Supplement 1): 30.

https://doi.org/10.1182/blood-2020-134886

Published: 2020

NARROW

Role of Autoantigen Induced-B-Cell Receptor Internalization and Its Inhibition for the Biology and Survival of Diffuse Large B-Cell Lymphoma (DLBCL) Cells

Epigenetic and Transcriptional Consequences of PIM Kinase Activity and Inhibition in Diffuse Large B-Cell Lymphoma (DLBCL)

Raman Spectroscopy Imaging in Evaluation of Immune Cells Activation Status

Label-Free Identification of Biochemical Footprints of Key Mutations in Acute Myeloid Leukemia Using Raman Spectroscopy

Raman Spectroscopy Imaging As a Tool to Classify Diffused Large B-Cell Lymphoma Subtypes

Transcriptomic Features Influencing Anti-Myeloma Drug Resistance in Human Multiple Myeloma Cell Lines

Novel Clinically Useful Inhibitor of Mediator Complex, RVU120, Relives Differentiation Block in MDS/AML

Targeting CDK8/CDK19 to Disrupt Leukemic Stem Cell-like Population in Acute Myeloid Leukemia: Exploring RVU120 As a Promising Frontline Therapy

PIM1 Point Mutations Increase Migration of Diffuse Large B-Cell Lymphoma (DLBCL) Cells

Super-Enhancer-Driven PIM Kinase Upregulation in Multiple Myeloma Maintains the Plasma Cell-Specific Oncogenic and Microenvironmental Circuits, and Can be Efficiently Targeted By the Pan-PIM Inhibitor MEN1703

Multiomics Analysis Confirms Effective Target Engagement for RVU120 - a First-in-Class CDK8/19 Kinase Inhibitor in AML and MR-MDS Patients and Reveals the Mechanism of Action

PIM Kinases Regulate Super-Enhancer-Dependent Gene Expression in Diffuse Large B-Cell Lymphoma

MEN1703-Mediated PIM Kinases Inhibition Impairs Protumoral and Immunosuppressive Phenotype and Functions of Macrophages in Classical Hodgkin Lymphoma

CD180 As a Putative Target for Immunotherapy in Aggressive Mature B Cell Lymphomas

Immunoregulatory CD71 + Erythroid Cells (CECs) Expand in Multiple Myeloma and Impair Control of L. Monocytogenes Infection

Preclinical and Clinical Signs of Efficacy of RVU120 (SEL120), a Specific CDK8/19 Inhibitor in DNMT3A-Mutated AML

RVU120 (SEL120) CDK8/19 Inhibitor - a Drug Candidate for the Treatment of MDS Can Induce Erythroid Differentiation

Inhibition of PIM Kinases in Diffuse Large B-Cell Lymphoma Cells Targets MYC-Dependent Transcriptional Program, Increases CD20 Expression and Augments the Efficacy of Anti-CD20 Antibodies

SIRT1 and HSP90alpha Are Functionally Linked and Control Mitotic Chromosome Segregation and Cell Viability in a Subset of Dlbcls

Hodgkin Lymphoma Reed-Sternberg Cells Induce Immunosuppressive and Pro-Angiogenic Phenotype of Tumor-Associated Macrophages in a Paracrine Manner

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American Society of Hematology

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American Society of Hematology

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