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Michael D Jain
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Journal Articles

Antibiotic-induced loss of gut microbiome metabolic output correlates with clinical responses to CAR T-cell therapy

Rishika Prasad, Abdur Rehman, Lubna Rehman, Faezeh Darbaniyan, Viktoria Blumenberg, Maria-Luisa Schubert, Uria Mor, Eli Zamir, Sabine Schmidt, Tomo Hayase, Chang Chia-Chi, Lauren Kelley McDaniel, Ivonne Flores, Paolo Strati, Ranjit Nair, Dai Chihara, Luis E. Fayad, Sairah Ahmed, Swaminathan P. Iyer, Michael L Wang, Preetesh Jain, Loretta J. Nastoupil, Jason R Westin, Reetakshi Arora, Joel Gordon Turner, Fareed Khawaja, Ranran Wu, Jennifer B Dennison, Meghan Menges, Melanie Hidalgo-Vargas, Kayla M. Reid, Marco L. Davila, Peter Dreger, Felix Korell, Anita Schmitt, Mark R Tanner, Richard E. Champlin, Christopher R. Flowers, Elizabeth J Shpall, Samir Hanash, Sattva S. Neelapu, Michael Schmitt, Marion Subklewe, Johannes Fahrmann, Christoph Stein-Thoeringer, Eran Elinav, Michael D Jain, Eiko Hayase, Robert R Jenq, Neeraj Y Saini
Journal: Blood
Blood blood.2024025366.
https://doi.org/10.1182/blood.2024025366
Published: 2024
Includes: Supplemental data
Journal Articles

A Novel Composite Endpoint of Toxicity- and Progression-Free Survival after B-Cell Maturation Antigen (BCMA)-Directed Chimeric Antigen Receptor T-Cell Therapy for Relapsed/Refractory Multiple Myeloma

Razan Mohty, Whiting Junmin, Aditi Saha, Jongphil Kim, Taiga Nishihori, Gabriel De Avila, Salvatore Corallo, Marian Dam, Jessica Marin, Hien Liu, Sepideh Mokhtari, Michael D. Jain, Fabiana Perna, Brandon Blue, Ariel F. Grajales-Cruz, Omar Castaneda, Kenneth Shain, Rachid Baz, Ciara Louise L. Freeman, Melissa Alsina, Frederick L. Locke, Doris K. Hansen, Aleksandr Lazaryan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3336.
https://doi.org/10.1182/blood-2023-184406
Published: 2023
Journal Articles

Five Year Outcomes of Patients with Large B-Cell Lymphoma Treated with Standard-of-Care Axicabtagene Ciloleucel: Results from the US Lymphoma CAR-T Cell Consortium

Jay Y. Spiegel, Michael D. Jain, Loretta J. Nastoupil, John Tamaresis, Armin Ghobadi, Yi Lin, Lazaros J. Lekakis, Patrick M. Reagan, Olalekan O. Oluwole, Joseph P McGuirk, Abhinav Deol, Kathleen Dorritie, Alison R Sehgal, Andre Goy, Brian T. Hill, Charalambos Andreadis, Javier L. Munoz, Matthew L. Ulrickson, Jason Westin, Julio C. Chavez, Dilan A Patel, Miriam T. Jacobs, Radhika Bansal, N. Nora Bennani, Vivek Patel, Aaron P. Rapoport, Julie M. Vose, David B. Miklos, Sattva S. Neelapu, Frederick L. Locke, Matthew A Lunning, Saurabh Dahiya
Journal: Blood
Blood (2023) 142 (Supplement 1): 1032.
https://doi.org/10.1182/blood-2023-179868
Published: 2023
Journal Articles

Predictors of Cytokine Release Syndrome and Neurotoxicity in Patients with Large B-Cell Lymphoma and Their Impact on Survival

Roni Shouval, Christopher Strouse, Soyoung Kim, Temitope Oloyede, Sairah Ahmed, Farrukh T. Awan, Veronika Bachanova, Talha Badar, Pere Barba, Amer M. Beitinjaneh, Amanda F Cashen, Bhagirathbhai Dholaria, Mahmoud Elsawy, Siddhartha Ganguly, Praveen Ramakrishnan Geethakumari, Uri Greenbaum, Hamza Hashmi, Laquisa C. Hill, Michael D. Jain, Tania Jain, Partow Kebriaei, Adam S Kittai, Frederick L. Locke, Premal D. Lulla, Elena Mead, Joseph P McGuirk, Alberto Mussetti, Taiga Nishihori, Amanda L. Olson, Martina Pennisi, Miguel-Angel Perales, Peter A. Riedell, Wael Saber, Sayeef Mirza, Margarida Magalhaes-Silverman, Elizabeth J. Shpall, Mohamed Sorror, Kitsada Wudhikarn, Cameron J. Turtle, Marcelo Pasquini, Amy Moskop
Journal: Blood
Blood (2023) 142 (Supplement 1): 355.
https://doi.org/10.1182/blood-2023-181181
Published: 2023
Journal Articles

Applying the Novel EHA/EBMT Grading System for Icaht Following CAR-T Therapy: Comparative Incidence across Disease Entities and Association with Infections and Mortality

Kai Rejeski, Doris K. Hansen, Yucai Wang, Gloria Iacoboni, Emmanuel Bachy, Radhika Bansal, Olaf Penack, Fabian Mueller, Wolfgang Andreas Bethge, Javier L. Munoz, Razan Mohty, Veit L. Buecklein, Pere Barba, Frederick L. Locke, Yi Lin, Michael D. Jain, Marion Subklewe
Journal: Blood
Blood (2023) 142 (Supplement 1): 359.
https://doi.org/10.1182/blood-2023-180607
Published: 2023
Journal Articles

Poor Hematopoietic Reserve at the Time of CD19 CAR T-Cell Infusion Is Associated with Long Term B-Cell Aplasia

Grace Johnson, Kedar Patel, Brian Arciola, Ariel Perez Perez, Anthony Wood, Filip Ionescu, Jennifer M Logue, Omar Albanyan, Hassaan Yasin, Christina A Bachmeier, Kayla Reid, Meghan Menges, Salvatore Corallo, Bijal D. Shah, Julio C Chavez, Farhad Khimani, Taiga Nishihori, Rawan Faramand, Hien Liu, Aleksandr Lazaryan, Kai Rejeski, Marion Subklewe, Fabiana Perna, Marco Davila, Rahul Mhaskar, Frederick L. Locke, Michael D. Jain
Journal: Blood
Blood (2023) 142 (Supplement 1): 3512.
https://doi.org/10.1182/blood-2023-185097
Published: 2023
Journal Articles

CAR-T Phenotype and Efficacy Is Impaired By Lymphoma-Associated CD39 + T Cells

Michael D. Jain, Xiaoqing Yu, Reginald Atkins, Joel G. Turner, Jerald Noble, Meghan Menges, Kayla Reid, Salvatore Corallo, Ling Cen, Sean J. Yoder, Julieta Abraham Miranda, Samira Naderinezhad, Hien Liu, Bijal D. Shah, Julio C Chavez, Erin Dean, Johannes Fahrmann, Neeraj Y. Saini, Samir Hanash, Rebecca S. Hesterberg, Paulo C. Rodriguez, John L. Cleveland, Marco Davila, Xuefeng Wang, Frederick L. Locke
Journal: Blood
Blood (2023) 142 (Supplement 1): 3500.
https://doi.org/10.1182/blood-2023-178113
Published: 2023
Journal Articles

Impact of Sarcopenia and Subsequent Muscle Loss on Post-CAR T-Cell Outcomes in Relapsed/Refractory Large B-Cell Lymphoma

Khushali Jhaveri, Ram Thapa, Jerald Noble, Dalia Ercan, Pranit Singh, Johannes Fahrmann, Neeraj Y. Saini, Ranran Wu, Jennifer Dennison, Samir Hanash, Robert R. Jenq, Karnav Modi, Nicholas Figura, Julio C Chavez, Bijal D. Shah, Taiga Nishihori, Aleksandr Lazaryan, Farhad Khimani, Christina A Bachmeier, Kenneth Gage, Asmita Mishra, Fabiana Perna, Marco Davila, Kai Rejeski, Marion Subklewe, Frederick L. Locke, Ciara Louise L. Freeman, Nathan Parker, Michael D. Jain
Journal: Blood
Blood (2023) 142 (Supplement 1): 2130.
https://doi.org/10.1182/blood-2023-187294
Published: 2023
Journal Articles

Clinical Impact of Neoantigen Burden and HLA Loss in Aggressive B-Cell Lymphomas Treated with CD19 CAR T-Cell

Bachisio Ziccheddu, Michael D. Jain, Monika Chojnacka, Michael Durante, Julieta Abraham Miranda, Meghan Menges, Ola Landgren, Marco Davila, Jonathan H. Schatz, Francesco Maura, Frederick L. Locke
Journal: Blood
Blood (2023) 142 (Supplement 1): 4362.
https://doi.org/10.1182/blood-2023-182821
Published: 2023
Journal Articles

Is CAR T a Drug or a Therapeutic Pathway? Systematic Review, (Re-)Estimation of Efficacy Endpoints and Metanalyses in Large B-Cell Lymphoma Real World Reports

Pier Luigi Zinzani, Rossana Di Staso, Beatrice Casadei, Frederick L. Locke, Michael D. Jain, Timothy Voorhees, Adam S Kittai, Mariana Bastos-Oreiro, Antonio Gutiérrez, Alejandro Martin Garcia-Sancho, Maria Jose Terol, Monica Mead, Michael J. Maranzano, Gloria Iacoboni, Pere Barba, Mi Kwon, Rebeca Bailen, Juan Luis Reguera, Agrima Mian, Brian T. Hill, Emmanuel Bachy, Franck Morschhauser, Roch Houot, Catherine Thieblemont, Steven Le Gouill, Riccardo Masetti, Davide Gori, Lisa Argnani
Journal: Blood
Blood (2023) 142 (Supplement 1): 6938.
https://doi.org/10.1182/blood-2023-178526
Published: 2023
Journal Articles

Second-Line Chimeric Antigen Receptor T Cell Therapy (CAR-T) As Standard of Care for Relapsed-Refractory Large B-Cell Lymphoma (LBCL)

Saurabh Dahiya, Jay Y. Spiegel, Dasom Lee, Turab Mohammed, Forat Lutfi, Anmol Goyal, Caroline Hana, Julio C Chavez, Filip Ionescu, Matthew J. Frank, Sushma Bharadwaj, Jose Sandoval-Sus, Amer M. Beitinjaneh, Lazaros J. Lekakis, Joseph P McGuirk, Frederick L. Locke, David B. Miklos, Michael D. Jain
Journal: Blood
Blood (2023) 142 (Supplement 1): 4876.
https://doi.org/10.1182/blood-2023-188918
Published: 2023
Journal Articles

CD19 Intron Retention Is Mechanism of CAR-T Treatment Resistance in Non-Hodgkin Lymphoma

Jerald Noble, Frederick L. Locke, Constanza Savid-Frontera, Michael D. Jain, Joel G. Turner, Julieta Abraham Miranda, Thushara W Madanayake, Samira Naderinezhad, Salvatore Corallo, Meghan Menges, Kayla Reid, Timothy J Robinson
Journal: Blood
Blood (2023) 142 (Supplement 1): 3506.
https://doi.org/10.1182/blood-2023-185074
Published: 2023
Journal Articles

Impact of Sex on Clinical Outcomes after CD19 CAR T-Cell Therapy for Large B-Cell Lymphoma: Response and Survival Are Significantly Superior in Female Compared to Male Patients

Veit L. Buecklein, Kai Rejeski, Ariel Perez, Gloria Iacoboni, Vindi Jurinovic, Soraya Kharboutli, Viktoria Blumenberg, Josephine Ackermann, Lisa Frölich, Grace Johnson, Kedar Patel, Brian Arciola, Rahul Mhaskar, Christian Schmidt, Anthony Wood, Eva Hoster, Andreas Mackensen, Frederick L. Locke, Michael von Bergwelt-Baildon, Fabian Mueller, Pere Barba, Michael D. Jain, Marion Subklewe
Journal: Blood
Blood (2023) 142 (Supplement 1): 3787.
https://doi.org/10.1182/blood-2023-186510
Published: 2023
Journal Articles

A Novel Composite Endpoint of Toxicity-Free, Progression-Free Survival (TPFS) after CD19-Directed Chimeric Antigen Receptor T-Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma

Aditi Saha, Razan Mohty, Junmin Whiting, Kristen Flores, Jongphil Kim, Taiga Nishihori, Julio C Chavez, Farhad Khimani, Doris K. Hansen, Fabiana Perna, Hien Liu, Bijal D. Shah, Marian Dam, Muhammad Jaffer, Sepideh Mokhtari, Hany Elmariah, Rawan Faramand, Christina A Bachmeier, Nelli Bejanyan, Frederick L. Locke, Michael D. Jain, Aleksandr Lazaryan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1776.
https://doi.org/10.1182/blood-2023-185117
Published: 2023
Journal Articles

Clinical Outcomes of Adults Undergoing Allogeneic Stem Cell Transplant for Secondary Acute Lymphoblastic Leukemia

Vivian Irizarry Gatell, Denise Kalos, Joseph A. Pidala, Hany Elmariah, Farhad Khimani, Asmita Mishra, Taiga Nishihori, Michael D. Jain, Michael Neider, Lia Perez, Sayeef Mirza, Bijal D. Shah, Leidy Lismeris Isenalumhe, Nelli Bejanyan, Aleksandr Lazaryan, Rawan Faramand
Journal: Blood
Blood (2023) 142 (Supplement 1): 2830.
https://doi.org/10.1182/blood-2023-180321
Published: 2023
Journal Articles

Post-Transplant Cyclophosphamide Equalizes Clinical Outcomes of Allogeneic Hematopoietic Cell Transplantation across Racial and Ethnic Populations

Teresa Caprice, Wenyi Fan, Jongphil Kim, Rawan Faramand, Asmita Mishra, Lia Perez, Farhad Khimani, Aleksandr Lazaryan, Jose L. Ochoa-Bayona, Hien Liu, Michael D. Jain, Michael Nieder, Claudio Anasetti, Taiga Nishihori, Joseph A. Pidala, Nelli Bejanyan, Hany Elmariah
Journal: Blood
Blood (2023) 142 (Supplement 1): 390.
https://doi.org/10.1182/blood-2023-186738
Published: 2023
Journal Articles

Multicenter, Real-World Study in Patients with R/R Large B-Cell Lymphoma (LBCL) Who Received Lisocabtagene Maraleucel (liso-cel) in the United States (US)

Jennifer L. Crombie, Loretta J. Nastoupil, Charalambos Andreadis, Iris Isufi, Bradley Hunter, Allison Winter, Brian Hess, Stefan K. Barta, Michael J. Frigault, Maria Lia Palomba, Natalie S. Grover, Michael D. Jain, Tamara K. Moyo, Sagar S. Patel, Priyanka A Pophali, David Bernasconi, Charimar Santiago Parrilla, Amani Kitali, Fei Fei Liu, Mecide Gharibo, Marcelo Pasquini
Journal: Blood
Blood (2023) 142 (Supplement 1): 104.
https://doi.org/10.1182/blood-2023-180242
Published: 2023
Journal Articles

Cladribine and Cyclophosphamide Lymphodepletion Prior to Axicabtagene Ciloleucel in Relapsed or Refractory Large B-Cell Lymphoma

Filip Ionescu, Bijal D. Shah, Meghan Menges, Kayla Reid, Hanna Bailey, Elizabeth DiMaggio, Rebecca Gonzalez, Christina A Bachmeier, Salvatore Corallo, Luis Cuadrado Delgado, Turab Mohammed, Taiga Nishihori, Farhad Khimani, Aleksandr Lazaryan, Hien Liu, Marco Davila, Fabiana Perna, Julio C Chavez, Frederick L. Locke, Michael D. Jain
Journal: Blood
Blood (2023) 142 (Supplement 1): 4884.
https://doi.org/10.1182/blood-2023-187078
Published: 2023
Journal Articles

Cladribine and Cyclophosphamide Lymphodepletion Prior to Brexucabtagene Autoleucel in Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia and Mantle Cell Lymphoma

Filip Ionescu, Rawan Faramand, Hanna Bailey, Christina A Bachmeier, Elizabeth DiMaggio, Turab Mohammed, Leidy Lismeris Isenalumhe, Frederick L. Locke, Michael D. Jain, Bijal D. Shah
Journal: Blood
Blood (2023) 142 (Supplement 1): 6904.
https://doi.org/10.1182/blood-2023-190973
Published: 2023
Journal Articles

Radiomic Features Prognosticates Treatment Response in CAR-T Cell Therapy

Yoganand Balagurunathan, Zhouping Wei, Jin Qi, Erin A. Dean, Zachary Thompson, Jung Choi, Michael D. Jain, Frederick L. Locke
Journal: Blood
Blood (2023) 142 (Supplement 1): 6126.
https://doi.org/10.1182/blood-2023-181908
Published: 2023