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Journal Articles

Spatial transcriptomics reveals profound subclonal heterogeneity and T-cell dysfunction in extramedullary myeloma

Blood (2024) 144 (20): 2121–2135.

https://doi.org/10.1182/blood.2024024590

Published: 2024

Includes: Supplemental data

Journal Articles

The Role of Clonally Expanded CD8 + Non-CAR-T Cells in Neurocognitive and Hypokinetic Movement Disorder after BCMA-Targeting CAR-T Cell Therapy

Blood (2024) 144 (Supplement 1): 7086.

https://doi.org/10.1182/blood-2024-202348

Published: 2024

Journal Articles

Implementing Hifi Sequencing for Enhanced Genomic and Methylome Characterization in Multiple Myeloma

Seungbin Han, Nazia Afrin, Bas Tolhuis, Marietta Truger, Peter Raab, Umair Munawar, Cornelia Vogt, Shilpa Kurian, Silvia Nerreter, Xiang Zhou, Claudia Haferlach, Hermann Einsele, Johannes Waldschmidt, Leo Rasche, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 7490.

https://doi.org/10.1182/blood-2024-207422

Published: 2024

Journal Articles

Multi-Omics Analysis of Proteasome Inhibitor Resistance in Multiple Myeloma

Seungbin Han, Chien-Yun Lee, Lenka Besse, Umair Munawar, Andrej Besse, Ann-Sohpie Hainold, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Xiang Zhou, Larissa Haertle, Johannes Waldschmidt, Christoph Driessen, Hermann Einsele, Leo Rasche, Bernhard Kuster, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 6817.

https://doi.org/10.1182/blood-2024-203352

Published: 2024

Journal Articles

Classic Anti-Myeloma Treatments Alter Circulating Immune Cell Subsets with Potential Implications for T Cell Immunotherapies in Multiple Myeloma

Xiang Zhou, Sarah Wiethe, Angelika Wolff, Max J Steinhardt, Nazia Afrin, Mara John, Christine Riedhammer, Xianghui Xiao, Umair Munawar, Julia Mersi, Seungbin Han, Johannes Waldschmidt, Angela Riedel, Max S. Topp, Johannes Duell, Hermann Einsele, K. Martin Kortüm, Leo Rasche

Blood (2024) 144 (Supplement 1): 4705.

https://doi.org/10.1182/blood-2024-203391

Published: 2024

Journal Articles

Phase 2 Study of Teclistamab-Based Induction Regimens in Patients with Transplant-Eligible (TE) Newly Diagnosed Multiple Myeloma (NDMM): Results from the GMMG-HD10/DSMM-XX (MajesTEC-5) Trial

Blood (2024) 144 (Supplement 1): 493.

https://doi.org/10.1182/blood-2024-206003

Published: 2024

Journal Articles

Balancing Treatment Intervals and Quality of Life in Multiple Myeloma Patients: Patient Perspectives and Recommendations

Anna Fleischer, Mohammad Barakat, Sofie-Katrin Kadel, Julia Mersi, Johannes Waldschmidt, Hermann Einsele, K. Martin Kortüm, Imad Maatouk, Leo Rasche

Blood (2024) 144 (Supplement 1): 284.

https://doi.org/10.1182/blood-2024-205037

Published: 2024

Journal Articles

Delayed Neurotoxicity after CAR-T in Multiple Myeloma: Results from a Global IMWG Registry

Blood (2024) 144 (Supplement 1): 4758.

https://doi.org/10.1182/blood-2024-201783

Published: 2024

Journal Articles

Bi-Allelic GPRC5D Alterations Provide Proliferative Advantage in Presence of Talquetamab

Umair Munawar, Seungbin Han, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Patrick Eiring, Julia Weingart, Xiang Zhou, Markus Sauer, Hermann Einsele, Leo Rasche, Johannes Waldschmidt, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 593.

https://doi.org/10.1182/blood-2024-200593

Published: 2024

Journal Articles

Activity of CAR-T Cells and Bispecific Antibodies in Multiple Myeloma with Extramedullary Involvement

Blood (2024) 144 (Supplement 1): 3792.4.

https://doi.org/10.1182/blood-2024-206735

Published: 2024

Journal Articles

GPRC5D Status Impacts CD38 Expression in Multiple Myeloma

Umair Munawar, Julia Weingart, Patrick Eiring, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Seungbin Han, Max J Steinhardt, Xiang Zhou, Markus Sauer, Hermann Einsele, Leo Rasche, Johannes Waldschmidt, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 3267.

https://doi.org/10.1182/blood-2024-204863

Published: 2024

Journal Articles

Resolving therapy resistance mechanisms in multiple myeloma by multiomics subclone analysis

Blood (2023) 142 (19): 1633–1646.

https://doi.org/10.1182/blood.2023019758

Published: 2023

Includes: Supplemental data

Journal Articles

Functional Characterization of GPRC5D alteration and Its Impact on Talquetamab Resistance in Relapsed/ Refractory Multiple Myeloma

Seungbin Han, Umair Munawar, Larissa Haertle, Cornelia Vogt, Silvia Nerreter, Eva Teufel, Xiang Zhou, Max Steinhardt, Florian Eisele, Peter Raab, Marietta Truger, Sara Dorado, Santiago Barrio, Claudia Haferlach, Joaquin Martínez-López, Hermann Einsele, Leo Rasche, Johannes M Waldschmidt, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 3323.

https://doi.org/10.1182/blood-2023-181607

Published: 2023

Journal Articles

Euroflow-Based Ultrasensitive NGF for the Evaluation of Bone Marrow Minimal Residual Disease in Multiple Myeloma

Paula Tabares Gaviria, Katharina Schmiedgen, Jayabhuvaneshwari Dhanraj, Hüsniye Dagdeviren, Amy Wilnit, Maria Ulbrich, Bruno Paiva, K. Martin Kortüm, Leo Rasche, Hermann Einsele, Andreas Beilhack, Johannes M Waldschmidt

Blood (2023) 142 (Supplement 1): 3342.

https://doi.org/10.1182/blood-2023-189095

Published: 2023

Journal Articles

Immune-Effector-Cell-Associated-Neurotoxicity-Syndrome (ICANS) Pathophysiology Is Mediated By Microglia TGF-β-Activated Kinase-1 Signaling

Janaki Manoja Vinnakota, Francesca Biavasco, Marius Schwabenland, Chintan Chhatbar, Rachael C Adams, Daniel Erny, Sandra Duquesne, Nadia El Khawanky, Henrike Salié, Dimitrios Athanassopoulos, Lukas Braun, Dominik Schmidt, Viktor Fetsch, Rebeka N. Javorniczky, Jenny N.H.G Ho, Reinhard Marks, Ralph Wäsch, Federico Simonetta, Geoffroy Andrieux, Dietmar Pfeifer, Gianni Monaco, Christian Capitini, Terry J. Fry, Thomas Blank, Bruce R Blazar, Eva-Maria Wagner Drouet, Matthias Theobald, Clemens Sommer, Matthias Stelljes, Christian Reicherts, Astrid Jeibmann, Jens Schittenhelm, Camelia-Maria Monoranu, Andreas Rosenwald, K. Martin Kortüm, Leo Rasche, Hermann Einsele, Philipp Tobias Meyer, Joachim Brumberg, Andreas Mackensen, Michael von Bergwelt-Baildon, Roland Coras, Nathalie L. Albert, Laura M. Bartos, Matthias Brendel, Adrien Holzgreve, Melanie Boerries, Crystal L. Mackall, Justus Duyster, Natalie Koehler, Felix Strübing, Bertram Bengsch, Marco Ruella, Marion Subklewe, Louisa von Baumgarten, Saar Gill, Marco Prinz, Robert Zeiser

Blood (2023) 142 (Supplement 1): 100.

https://doi.org/10.1182/blood-2023-184867

Published: 2023

Journal Articles

Differential CD38 Expression on Daratumumab-Naïve Vs. Resistant Multiple Myeloma - a Direct Stochastic Optical Reconstruction Microscopy ( d STORM) Analysis in 53 Patients

Maximilian J Steinhardt, Patrick Eiring, Cornelia Vogt, Umair Munawar, Seungbin Han, Larissa Haertle, Silvia Nerreter, Eva Teufel, Julia Mersi, Xiang Zhou, Michael Hudecek, Joaquin Martinez-Lopez, Johannes M Waldschmidt, Hermann Einsele, Leo Rasche, Markus Sauer, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 1992.

https://doi.org/10.1182/blood-2023-189741

Published: 2023

Journal Articles

Clinical and Diagnostic Challenges in Patients with Concomitant Plasma Cell Disorders and Myeloproliferative Neoplasms

Maximilian J Steinhardt, Thomas Bumm, Xiang Zhou, Umair Munawar, Seungbin Han, Julia Mersi, Hermann Einsele, Leo Rasche, K. Martin Kortüm, Johannes M Waldschmidt

Blood (2023) 142 (Supplement 1): 6771.

https://doi.org/10.1182/blood-2023-189528

Published: 2023

Journal Articles

Secondary Genetic Events Impact the Expression of Key Immunotargets on the Surface of Multiple Myeloma Cells

Umair Munawar, Patrick Eiring, Cornelia Vogt, Larissa Haertle, Seungbin Han, Silvia Nerreter, Eva Teufel, Max Steinhardt, Xiang Zhou, Santiago Barrio, Hermann Einsele, Johannes M Waldschmidt, Leo Rasche, Markus Sauer, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 451.

https://doi.org/10.1182/blood-2023-180638

Published: 2023

Journal Articles

The Impact of Treatment-Free Intervals on T-Cell Exhaustion and Clonotypic Diversity in Myeloma Patients Treated with BCMA Bispecific Antibodies

Florian Eisele, Nazia Afrin, Emilia Stanojkovska, Mara John, Moutaz Helal, Lars Grundheber, Philipp Weis, Christine Riedhammer, Sofie-Katrin Kadel, Max Steinhardt, Johannes Duell, Johannes M Waldschmidt, Hermann Einsele, Angela Riedel, K. Martin Kortüm, Leo Rasche

Blood (2023) 142 (Supplement 1): 1938.

https://doi.org/10.1182/blood-2023-189042

Published: 2023

Journal Articles

Intracytoplasmatic BCMA Point Mutation and Teclistamab Resistance: Genomic Assessment of a Multidrug-Resistant Multiple Myeloma Patient

Natalia Buenache Cuenda, Hipolito Nicolas Cuesta Hernández, Alicia Giménez Sánchez, Laura Carneros Blanco, Juan Manuel Rosa-Rosa, Yanira Ruiz-Heredia, Enrique Revilla, Seungbin Han, Umair Munawar, Inmaculada Rapado, Rosa Ayala, K. Martin Kortüm, Antonio Valeri, Santiago Barrio, Joaquin Martinez Lopez, Larissa Haertle

Blood (2023) 142 (Supplement 1): 1925.

https://doi.org/10.1182/blood-2023-184824

Published: 2023

NARROW

Spatial transcriptomics reveals profound subclonal heterogeneity and T-cell dysfunction in extramedullary myeloma

The Role of Clonally Expanded CD8 + Non-CAR-T Cells in Neurocognitive and Hypokinetic Movement Disorder after BCMA-Targeting CAR-T Cell Therapy

Implementing Hifi Sequencing for Enhanced Genomic and Methylome Characterization in Multiple Myeloma

Multi-Omics Analysis of Proteasome Inhibitor Resistance in Multiple Myeloma

Classic Anti-Myeloma Treatments Alter Circulating Immune Cell Subsets with Potential Implications for T Cell Immunotherapies in Multiple Myeloma

Phase 2 Study of Teclistamab-Based Induction Regimens in Patients with Transplant-Eligible (TE) Newly Diagnosed Multiple Myeloma (NDMM): Results from the GMMG-HD10/DSMM-XX (MajesTEC-5) Trial

Balancing Treatment Intervals and Quality of Life in Multiple Myeloma Patients: Patient Perspectives and Recommendations

Delayed Neurotoxicity after CAR-T in Multiple Myeloma: Results from a Global IMWG Registry

Bi-Allelic GPRC5D Alterations Provide Proliferative Advantage in Presence of Talquetamab

Activity of CAR-T Cells and Bispecific Antibodies in Multiple Myeloma with Extramedullary Involvement

GPRC5D Status Impacts CD38 Expression in Multiple Myeloma

Resolving therapy resistance mechanisms in multiple myeloma by multiomics subclone analysis

Functional Characterization of GPRC5D alteration and Its Impact on Talquetamab Resistance in Relapsed/ Refractory Multiple Myeloma

Euroflow-Based Ultrasensitive NGF for the Evaluation of Bone Marrow Minimal Residual Disease in Multiple Myeloma

Immune-Effector-Cell-Associated-Neurotoxicity-Syndrome (ICANS) Pathophysiology Is Mediated By Microglia TGF-β-Activated Kinase-1 Signaling

Differential CD38 Expression on Daratumumab-Naïve Vs. Resistant Multiple Myeloma - a Direct Stochastic Optical Reconstruction Microscopy ( d STORM) Analysis in 53 Patients

Clinical and Diagnostic Challenges in Patients with Concomitant Plasma Cell Disorders and Myeloproliferative Neoplasms

Secondary Genetic Events Impact the Expression of Key Immunotargets on the Surface of Multiple Myeloma Cells

The Impact of Treatment-Free Intervals on T-Cell Exhaustion and Clonotypic Diversity in Myeloma Patients Treated with BCMA Bispecific Antibodies

Intracytoplasmatic BCMA Point Mutation and Teclistamab Resistance: Genomic Assessment of a Multidrug-Resistant Multiple Myeloma Patient

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American Society of Hematology

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American Society of Hematology

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