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Journal Articles

Outcome of Intensively Treated Elderly AML Patients Reported to the Harmony Alliance Compares Well to Outcome of Control Patients of the Prospective Randomized HOVON 103 Study in Elderly AML

Sjoerd J.F. Hermans, Jurjen Versluis, Yvette van Norden, Erik D. van Werkhoven, Jeroen J.W.M. Janssen, Gerwin A. Huls, Bob Lowenberg, Thomas Pabst, Dimitri A. Breems, Elizabeth Berkx, Avinash G. Dinmohamed, Peter C. Huijgens, Eric Sträng, Jesús María Hernández-Rivas, Hartmut Döhner, Marta Sobas, Lars Bullinger, Rosa Ayala, Joaquin Martinez-Lopez, Klaus H Metzeler, Torsten Haferlach, Christian Thiede, Carin A. Uyl-De Groot, Gert J. Ossenkoppele, Francesco Pignatti, Jan J. Cornelissen
Journal: Blood
Blood (2023) 142 (Supplement 1): 2854.
https://doi.org/10.1182/blood-2023-186277
Published: 2023
Journal Articles

Machine Learning Provides Individualized Prediction of Outcomes after First Complete Remission in Adult AML Patients - Results from the Harmony Platform

Alberto Hernández Sánchez, Javier Martínez Elicegui, Marta Sobas, Eric Sträng, Axel Benner, María Abáigar, Gastone Castellani, Laura Tur, Peter J. M. Valk, Angela Villaverde Ramiro, Klaus H Metzeler, Raúl Azibeiro Melchor, Jurjen Versluis, Daniele Dall'Olio, Teresa González, Jesse M. Tettero, Joaquin Martinez-Lopez, Helena Fidalgo, Jorge Sierra, Frederik Damm, Ken I Mills, Soren Lehmann, Ian Thomas, Jiří Mayer, Christian Thiede, Maria Teresa Voso, Guillermo Sanz, Konstanze Döhner, Michael Heuser, Torsten Haferlach, Amin T. Turki, Dirk Reinhardt, Michel van Speybroeck, Renate Schulze-Rath, Martje Barbus, John E Butler, Jesús María Hernández-Rivas, Brian Huntly, Gert Ossenkoppele, Hartmut Döhner, Lars Bullinger
Journal: Blood
Blood (2023) 142 (Supplement 1): 62.
https://doi.org/10.1182/blood-2023-183029
Published: 2023
Journal Articles

Machine Learning Allows the Identification of New Co-Mutational Patterns with Prognostic Implications in NPM1 Mutated AML - Results of the European Harmony Alliance

Alberto Hernández Sánchez, Angela Villaverde Ramiro, Eric Sträng, Castellani Gastone, Caroline A. Heckman, Jurjen Versluis, María Abáigar, Marta Anna Sobas, Raúl Azibeiro Melchor, Axel Benner, Peter JM Valk, Klaus H. Metzeler, Teresa González, Daniele Dall'Olio, Jesse M. Tettero, Javier Martinez Elicegui, Joaquín Martínez-López, Marta Pratcorona, Frederik Damm, Ken I Mills, Christian Thiede, Maria Teresa Voso, Guillermo Sanz, Konstanze Döhner, Michael Heuser, Torsten Haferlach, Amin T. Turki, Rubén Villoria Medina, Michel van Speybroeck, Renate Schulze-Rath, Martje Barbus, John E Butler, Jesús María Hernández-Rivas, Brian James Patrick Huntly, Gert Ossenkoppele, Hartmut Döhner, Lars Bullinger
Journal: Blood
Blood (2022) 140 (Supplement 1): 739–742.
https://doi.org/10.1182/blood-2022-167138
Published: 2022
Journal Articles

Long-Term Follow-up of AML Patients Treated Intensively before the Era of Targeted Agents. a Big Data Analysis from the Harmony Collaboration

Marta Anna Sobas, Angela Villaverde Ramiro, Alberto Hernández Sánchez, Javier Martinez Elicegui, Teresa González, Raúl Azibeiro Melchor, María Abáigar, Laura Tur, Daniele Dall'Olio, Eric Sträng, Jesse M. Tettero, Castellani Gastone, Axel Benner, Konstanze Döhner, Christian Thiede, Amin T. Turki, Klaus H. Metzeler, Torsten Haferlach, Frederick Damm, Rosa Ayala, Joaquín Martínez-López, Ken I Mills, Jorge Sierra, Sören Lehmann, Matteo G. Della Porta, Jiri Mayer, Dirk Reinhardt, Rubén Villoria Medina, Renate Schulze-Rath, Martje Barbus, Jesús María Hernández-Rivas, Brian James Patrick Huntly, Gert Ossenkoppele, Hartmut Dohner, Lars Bullinger
Journal: Blood
Blood (2022) 140 (Supplement 1): 6053–6055.
https://doi.org/10.1182/blood-2022-165088
Published: 2022
Journal Articles

Rapid and Reproducible Karyotyping with Nanopore Sequencing in AML Patients

Michael Heuser, Nouraldin Damrah, Razif Gabdoulline, Courteney K. Lai, Eric Sträng, Mustafa Salim, Gudrun Göhring, Yvonne L. Behrens, Ekaterina Jahn, Martin Wichmann, Jens F. Schrezenmeier, Yasmine Alwie, Joerg Westermann, Frederick Damm, Brigitte Schlegelberger, Frank G. Rücker, Hartmut Döhner, Arnold Ganser, Felicitas R. Thol, Olga Blau, Konstanze Döhner, Lars Bullinger, Anna Dolnik
Journal: Blood
Blood (2022) 140 (Supplement 1): 6070–6072.
https://doi.org/10.1182/blood-2022-163035
Published: 2022
Journal Articles

Rearrangements Involving 11q23/ KMT2A : Mutational Landscape and Prognostic Implications - Results of the Harmony Alliance AML Database

Alberto Hernández Sánchez, Teresa González, Marta Anna Sobas, Eric Sträng, Castellani Gastone, María Abáigar, Peter JM Valk, Angela Villaverde Ramiro, Axel Benner, Klaus H. Metzeler, Jesse M. Tettero, Joaquín Martínez-López, Marta Pratcorona, Javier Martinez Elicegui, Ken I Mills, Christian Thiede, Guillermo Sanz, Konstanze Döhner, Michael Heuser, Torsten Haferlach, Amin T. Turki, Dirk Reinhardt, Renate Schulze-Rath, Martje Barbus, Jesús María Hernández-Rivas, Brian James Patrick Huntly, Gert Ossenkoppele, Hartmut Döhner, Lars Bullinger
Journal: Blood
Blood (2022) 140 (Supplement 1): 551–554.
https://doi.org/10.1182/blood-2022-167480
Published: 2022
Journal Articles

Harmony Alliance Provides a Machine Learning Researching Tool to Predict the Risk of Relapse after First Remission in AML Patients Treated without Allogeneic Haematopoietic Stem Cell Transplantation

Marta Sobas, Javier Martinez Elicegui, Angela Villaverde Ramiro, Teresa González, Alberto Hernandez-Sanchez, Raúl Azibeiro Melchor, Axel Benner, Eric Sträng, Castellani Gastone, Caroline A. Heckman, Ana Heredia Casanoves, Jurjen Versluis, María Abáigar, Laura Jamilis, Peter JM Valk, Klaus H. Metzeler, Rosa Ayala, Joaquin Martinez Lopez, Hervé Dombret, Jorge Sierra, Claude Preudomme, Frederick Damm, Ken I Mills, Jiří Mayer, Christian Thiede, Maria Teresa Voso, Sergio Amadori, Guillermo Sanz, Frederico Calado, Konstanze Döhner, Verena I Gaidzik, Michael Heuser, Torsten Haferlach, Amin T. Turki, Dirk Reinhardt, Rubén Villoria Medina, Michel Van Speybroeck, Renate Schulze-Rath, John E Butler, Brian J.P Huntly, Hartmut Dohner, Gert J. Ossenkoppele, Lars Bullinger, Jesus Maria Hernández-Rivas
Journal: Blood
Blood (2021) 138 (Supplement 1): 4041.
https://doi.org/10.1182/blood-2021-149521
Published: 2021
Journal Articles

Impact of Gender on Molecular AML Subclasses - a Harmony Alliance Study

Tommaso Matteuzzi, Daniele Dall'Olio, Eric Sträng, Alessandra Merlotti, Javier Martinez Elicegui, Axel Benner, Maral Saadati, Julia Krzykalla, Caroline A. Heckman, Ana Heredia Casanoves, Jurjen Versluis, María Abáigar, Alberto Hernandez-Sanchez, Laura Jamilis, Peter JM Valk, Klaus H. Metzeler, Rosa Ayala, Joaquin Martinez Lopez, Herve Dombret, Pau Montesinos, Jorge Sierra, Claude Preudomme, Frederick Damm, Ken I Mills, Raúl Azibeiro Melchor, Jiří Mayer, Christian Thiede, Maria Teresa Voso, Sergio Amadori, Guillermo Sanz, Frederico Calado, Konstanze Döhner, Verena I Gaidzik, Michael Heuser, Torsten Haferlach, Marta Sobas, Amin T. Turki, Dirk Reinhardt, Rubén Villoria Medina, Michel van Speybroeck, Renate Schulze-Rath, Jesús M Hernández Rivas, Brian J.P Huntly, Hartmut Döhner, Gert J. Ossenkoppele, Castellani Gastone, Lars Bullinger
Journal: Blood
Blood (2021) 138 (Supplement 1): 3438.
https://doi.org/10.1182/blood-2021-152215
Published: 2021
Journal Articles

Does RAD21 Co-Mutation Have a Role in DNMT3A Mutated AML? Results of Harmony Alliance AML Database

Raúl Azibeiro Melchor, Alberto Hernández Sánchez, Teresa González, Marta Sobas, Javier Martinez Elicegui, Angela Villaverde Ramiro, Axel Benner, Eric Sträng, Castellani Gastone, Caroline A. Heckman, Ana Heredia Casanoves, Jurjen Versluis, María Abáigar, Laura Jamilis, Peter JM Valk, Klaus H. Metzeler, Rosa Ayala, Herve Dombret, Jorge Sierra, Claude Preudomme, Frederick Damm, Ken I Mills, Jiří Mayer, Christian Thiede, Maria Teresa Voso, Sergio Amadori, Guillermo Sanz, Frederico Calado, Konstanze Döhner, Verena I Gaidzik, Michael Heuser, Torsten Haferlach, Amin T. Turki, Dirk Reinhardt, Rubén Villoria Medina, Michel van Speybroeck, Renate Schulze-Rath, John E Butler, Brian J.P Huntly, Jesús M Hernández Rivas, Lars Bullinger, Hartmut Döhner, Gert J. Ossenkoppele
Journal: Blood
Blood (2021) 138 (Supplement 1): 608.
https://doi.org/10.1182/blood-2021-150766
Published: 2021
Journal Articles

Clonal evolution of acute myeloid leukemia with FLT3 -ITD mutation under treatment with midostaurin

Laura K. Schmalbrock, Anna Dolnik, Sibylle Cocciardi, Eric Sträng, Frauke Theis, Nikolaus Jahn, Ekaterina Panina, Tamara J. Blätte, Julia Herzig, Sabrina Skambraks, Frank G. Rücker, Verena I. Gaidzik, Peter Paschka, Walter Fiedler, Helmut R. Salih, Gerald Wulf, Thomas Schroeder, Michael Lübbert, Richard F. Schlenk, Felicitas Thol, Michael Heuser, Richard A. Larson, Arnold Ganser, Hendrik G. Stunnenberg, Saverio Minucci, Richard M. Stone, Clara D. Bloomfield, Hartmut Döhner, Konstanze Döhner, Lars Bullinger
Journal: Blood
Blood (2021) 137 (22): 3093–3104.
https://doi.org/10.1182/blood.2020007626
Published: 2021
Includes: Supplemental data
Journal Articles

Mutational Landscape of Relapsed Core-Binding Factor Acute Myeloid Leukemia (CBF-AML)

Anna Dolnik, Nikolaus Jahn, MD, Eric Sträng, PhD, Sibylle Cocciardi, PhD, Frank G. Rücker, MD, Ekaterina Panina, MD, Tamara J. Blätte, PhD, Julia Katharina Herzig, PhD, Andrea Corbacioglu, PhD, Daniela Weber, MSc, Anika Schrade, PhD, Verena I Gaidzik, MD, Sabrina Skambraks, Katharina S. Götze, Michael Luebbert, MD PhD, Walter Fiedler, MD, Thomas Schroeder, Corinna Hahn, Felicitas Thol, Michael Heuser, Arnold Ganser, Peter Paschka, MD, Hartmut Döhner, Konstanze Döhner, Lars Bullinger, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42.
https://doi.org/10.1182/blood-2020-142392
Published: 2020
Journal Articles

Integration of Hi-C and Nanopore Sequencing for Structural Variant Analysis in AML with a Complex Karyotype: (Chromothripsis)²

Marius-Konstantin Klever, Eric Sträng, PhD, Julius Jungnitsch, Uirá Souto Melo, Sara Hetzel, Anna Dolnik, Robert Schöpflin, Jens F. Schrezenmeier, Olga Blau, Jörg Westermann, Konstanze Döhner, Hubert Schrezenmeier, Malte Spielmann, Alexander Meissner, PhD, Stefan Mundlos, Lars Bullinger, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28.
https://doi.org/10.1182/blood-2020-133787
Published: 2020