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Issue Archive

Volume 133, Issue 22
May 30 2019
Issue Cover

Table of Contents

BLOOD COMMENTARIES

PLATELETS AND THROMBOPOIESIS
New IDEaS for HIT treatment, anyone?
Anand Padmanabhan
View Articletitled, New IDEaS for HIT treatment, anyone?
Red Cells, Iron, and Erythropoiesis
Brain O2 reserve in sickle cell disease
John C. Wood
View Articletitled, Brain O<sub>2</sub> reserve in sickle cell disease

BLOOD SPOTLIGHT

Tumor-educated platelets
Sjors G. J. G. In ‘t Veld,Thomas Wurdinger
View Articletitled, Tumor-educated platelets

REVIEW ARTICLE

RNA-binding proteins in hematopoiesis and hematological malignancy
Daniel J. Hodson,Michael Screen,Martin Turner
View Articletitled, RNA-binding proteins in hematopoiesis and hematological malignancy

HOW I TREAT

How I treat chronic myeloid leukemia in children and adolescents
Clinical Trials & Observations
Nobuko Hijiya,Meinolf Suttorp
View Articletitled, How I treat chronic myeloid leukemia in children and adolescents

HEMATOPOIESIS AND STEM CELLS

Asrij/OCIAD1 suppresses CSN5-mediated p53 degradation and maintains mouse hematopoietic stem cell quiescence
Saloni Sinha,Tirath Raj Dwivedi,Roja Yengkhom,Venkata Anudeep Bheemsetty,Takaya Abe,Hiroshi Kiyonari,K. VijayRaghavan,Maneesha S. Inamdar
View Articletitled, Asrij/OCIAD1 suppresses CSN5-mediated p53 degradation and maintains mouse hematopoietic stem cell quiescence
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas
Marién Pascual,María Mena-Varas,Eloy Francisco Robles,Maria-Jose Garcia-Barchino,Carlos Panizo,Sandra Hervas-Stubbs,Diego Alignani,Ainara Sagardoy,Jose Ignacio Martinez-Ferrandis,Karen L. Bunting,Stephen Meier,Xavier Sagaert,Davide Bagnara,Elizabeth Guruceaga,Oscar Blanco,Jon Celay,Alvaro Martínez-Baztan,Noelia Casares,Juan José Lasarte,Thomas MacCarthy,Ari Melnick,Jose Angel Martinez-Climent,Sergio Roa
View Articletitled, PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas
Supplemental data

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

Trib1 regulates eosinophil lineage commitment and identity by restraining the neutrophil program
Ethan A. Mack,Sarah J. Stein,Kelly S. Rome,Lanwei Xu,Gerald B. Wertheim,Rossana C. N. Melo,Warren S. Pear
View Articletitled, Trib1 regulates eosinophil lineage commitment and identity by restraining the neutrophil program
Supplemental data

PLATELETS AND THROMBOPOIESIS

Cleavage of anti-PF4/heparin IgG by a bacterial protease and potential benefit in heparin-induced thrombocytopenia
Claire Kizlik-Masson,Quentin Deveuve,Yuhang Zhou,Caroline Vayne,Gilles Thibault,Steven E. McKenzie,Claire Pouplard,Stéphane Loyau,Yves Gruel,Jérôme Rollin

There is a Blood Commentary on this article in this issue.

View Articletitled, Cleavage of anti-PF4/heparin IgG by a bacterial protease and potential benefit in heparin-induced thrombocytopenia
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Hydroxyurea reduces cerebral metabolic stress in patients with sickle cell anemia
Melanie E. Fields,Kristin P. Guilliams,Dustin Ragan,Michael M. Binkley,Amy Mirro,Slim Fellah,Monica L. Hulbert,Morey Blinder,Cihat Eldeniz,Katie Vo,Joshua S. Shimony,Yasheng Chen,Robert C. McKinstry,Hongyu An,Jin-Moo Lee,Andria L. Ford
View Articletitled, Hydroxyurea reduces cerebral metabolic stress in patients with sickle cell anemia

THROMBOSIS AND HEMOSTASIS

Dysfunctional endogenous FIX impairs prophylaxis in a mouse hemophilia B model
Brian Cooley,George J. Broze, Jr,David M. Mann,Feng-Chang Lin,Lee G. Pedersen,Darrel W. Stafford
View Articletitled, Dysfunctional endogenous FIX impairs prophylaxis in a mouse hemophilia B model

LETTERS TO BLOOD

Clinically indicated ibrutinib dose interruptions and reductions do not compromise long-term outcomes in CLL
Clinical Trials & Observations
Inhye E. Ahn,Neil Basumallik,Xin Tian,Susan Soto,Adrian Wiestner
View Articletitled, Clinically indicated ibrutinib dose interruptions and reductions do not compromise long-term outcomes in CLL
Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis
Cuong Quang Le,Greggory Myers,Alawi Habara,Natee Jearawiriyapaisarn,George J. Murphy,David H. K. Chui,Martin H. Steinberg,James Douglas Engel,Shuaiying Cui
View Articletitled, Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis
Supplemental data

BLOOD WORK

Follicular lymphoma with composite in situ mantle cell neoplasia
Antonio Subtil,Zhaodong Xu
View Articletitled, Follicular lymphoma with composite in situ mantle cell neoplasia
All Issues

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Data mining for second malignancies after CAR-T
Silva A, Almeida ARM, Cachucho A, et al. Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma. Blood. 2021;138(12):1040-1052.
MRD and EFS in pediatric T-lymphoblastic lymphoma
Outcomes of younger patients with mantle-cell lymphoma experiencing late relapse (>24 months): the LATE-POD study
Mutational profile of previously treated chronic lymphocytic leukemia patients progressing on acalabrutinib or ibrutinib

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